James Topping

Journal Article J Am Med Inform Assoc · August 16, 2022 OBJECTIVE: The Rapid Acceleration of Diagnostics-Underserved Populations (RADx-UP) program is a consortium of community-engaged research projects with the goal of increasing access to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) tests in un ... Full text Link to item Cite

Improving and sustaining the site investigator community: Recommendations from the Clinical Trials Transformation Initiative.

Journal Article Contemp Clin Trials Commun · December 2019 The Clinical Trials Transformation Initiative (CTTI) Strengthening the Investigator Community Project was prompted by the need to understand the reasons for high rates of turnover among investigators who lead US Food and Administration-regulated clinical t ... Full text Link to item Cite

Trends in clinical trial investigator workforce and turnover: An analysis of the U.S. FDA 1572 BMIS database.

Journal Article Contemp Clin Trials Commun · September 2019 BACKGROUND: High turnover rates among clinical trial investigators contribute to inefficiency, instability, and increased costs for the clinical research enterprise; however, factors contributing to investigator turnover have not been well characterized. M ... Full text Link to item Cite

Compliance with results reporting at ClinicalTrials.gov.

Journal Article N Engl J Med · March 12, 2015 BACKGROUND: The Food and Drug Administration Amendments Act (FDAAA) mandates timely reporting of results of applicable clinical trials to ClinicalTrials.gov. We characterized the proportion of applicable clinical trials with publicly available results and ... Full text Open Access Link to item Cite

Effects of exercise training amount on physical activity energy expenditure.

Journal Article Med Sci Sports Exerc · August 2009 INTRODUCTION: We examined the effects of three exercise training interventions on total physical activity energy expenditure (PAEE) or nonexercise PAEE in a randomized controlled trial where sedentary, overweight, and obese men and women were assigned to i ... Full text Link to item Cite

Relation of serum retinol to acute phase proteins and malarial morbidity in Papua New Guinea children.

Journal Article The American journal of clinical nutrition · June 2000 BackgroundAcute phase proteins (APPs) are associated with malaria-induced hyporetinemia (serum retinol <0.70 micromol/L); however, the degree of the association is not well documented.ObjectiveThe association between malaria-induced hypor ... Full text Cite