Jessilyn Dunn
Assistant Professor of Biomedical Engineering
Developing new tools and infrastructure for multi-modal biomedical data integration to drive precision/personalized methods for early detection, intervention, and prevention of disease.
Current Appointments & Affiliations
- Assistant Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2019
- Assistant Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2019
- Assistant Professor in the Department of Electrical and Computer Engineering, Electrical and Computer Engineering, Pratt School of Engineering 2020
- Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2018
Contact Information
- Suite 1102 Hock Plaza, Box 2721, Durham, NC 27708
- Suite 1102 Hock Plaza, Box 2721, Durham, NC 27710
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Dunn Lab
- Background
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Education, Training, & Certifications
- Ph.D., Georgia Institute of Technology 2015
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Duke Appointment History
- Visiting AssistantProfessor in the Department of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2018
- Recognition
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In the News
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FEB 10, 2021 -
AUG 25, 2020 Duke Magnify -
JUL 22, 2020 School of Medicine -
JUN 15, 2020 Pratt School of Engineering -
MAY 15, 2020 -
APR 8, 2020 Pratt School of Engineering -
APR 6, 2020 -
FEB 11, 2020 Pratt School of Engineering -
JUN 5, 2018 Duke University Pratt School of Engineering
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- Research
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Selected Grants
- Duke RDS2 (Respondent-Driven Sampling, Respiratory Disease Surveillance) the SNOWBALL Sampling Study awarded by Centers for Disease Control and Prevention 2020 - 2022
- AMETHYST Trial Collaboration awarded by AstraZeneca LP 2020 - 2022
- CovIdentify: Using Mobile Health Technologies to Detect and Monitor COVID-19 in Essential Workers in North Carolina awarded by North Carolina Biotechnology Center 2020 - 2021
- Expanding the Open mHealth Platform to include a Digital Biomarker Discovery Pipeline (DBDP) awarded by Chan Zuckerberg Initiative 2020 - 2021
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External Relationships
- AstraZeneca
- Chan Zuckerberg Initiative / Silicon Valley Community Fund
- Clinetic (formerly MedBlue Data)
- Peloton
- The Digital Medicine Society
- npj Digital Medicine
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Bent, Brinnae, Oana M. Enache, Benjamin Goldstein, Warren Kibbe, and Jessilyn P. Dunn. “Reply: Matters Arising 'Investigating sources of inaccuracy in wearable optical heart rate sensors'.” Npj Digit Med 4, no. 1 (February 26, 2021): 39. https://doi.org/10.1038/s41746-021-00409-4.Full Text Link to Item
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Bent, Brinnae, Ida Sim, and Jessilyn P. Dunn. “Digital Medicine Community Perspectives and Challenges: Survey Study.” Jmir Mhealth and Uhealth 9, no. 2 (February 3, 2021): e24570. https://doi.org/10.2196/24570.Full Text
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Bent, Brinnae, Ke Wang, Emilia Grzesiak, Chentian Jiang, Yuankai Qi, Yihang Jiang, Peter Cho, et al. “The digital biomarker discovery pipeline: An open-source software platform for the development of digital biomarkers using mHealth and wearables data.” Journal of Clinical and Translational Science 5, no. 1 (2021). https://doi.org/10.1017/cts.2020.511.Full Text
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Bent, Brinnae, and Jessilyn P. Dunn. “Optimizing sampling rate of wrist-worn optical sensors for physiologic monitoring.” Journal of Clinical and Translational Science 5, no. 1 (2021). https://doi.org/10.1017/cts.2020.526.Full Text
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Bent, Brinnae, and Jessilyn P. Dunn. “Wearables in the SARS-CoV-2 Pandemic: What Are They Good for?” Jmir Mhealth and Uhealth 8, no. 12 (December 22, 2020): e25137. https://doi.org/10.2196/25137.Full Text
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Jiang, Yihang, Yuankai Qi, Will Ke Wang, Brinnae Bent, Robert Avram, Jeffrey Olgin, and Jessilyn Dunn. “EventDTW: An Improved Dynamic Time Warping Algorithm for Aligning Biomedical Signals of Nonuniform Sampling Frequencies.” Sensors (Basel, Switzerland) 20, no. 9 (May 9, 2020). https://doi.org/10.3390/s20092700.Full Text
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Bent, Brinnae, Benjamin A. Goldstein, Warren A. Kibbe, and Jessilyn P. Dunn. “Investigating sources of inaccuracy in wearable optical heart rate sensors.” Npj Digit Med 3, no. 1 (February 10, 2020): 18. https://doi.org/10.1038/s41746-020-0226-6.Full Text Link to Item
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Bent, Brinnae, Benjamin A. Goldstein, Warren A. Kibbe, and Jessilyn P. Dunn. “Investigating sources of inaccuracy in wearable optical heart rate sensors.” Npj Digit Med 3 (2020): 18. https://doi.org/10.1038/s41746-020-0226-6.Full Text Open Access Copy Link to Item
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Goldsack, Jennifer C., Andrea Coravos, Jessie P. Bakker, Brinnae Bent, Ariel V. Dowling, Cheryl Fitzer-Attas, Alan Godfrey, et al. “Verification, analytical validation, and clinical validation (V3): the foundation of determining fit-for-purpose for Biometric Monitoring Technologies (BioMeTs).” Npj Digital Medicine 3 (January 2020): 55. https://doi.org/10.1038/s41746-020-0260-4.Full Text
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Witt, Daniel R., Ryan A. Kellogg, Michael P. Snyder, and Jessilyn Dunn. “Windows into human health through wearables data analytics.” Current Opinion in Biomedical Engineering 9 (March 2019): 28–46. https://doi.org/10.1016/j.cobme.2019.01.001.Full Text Open Access Copy
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Rego, Shannon, Orit Dagan-Rosenfeld, Wenyu Zhou, M Reza Sailani, Patricia Limcaoco, Elizabeth Colbert, Monika Avina, et al. “High-frequency actionable pathogenic exome variants in an average-risk cohort.” Molecular Case Studies 4, no. 6 (December 2018): a003178–a003178. https://doi.org/10.1101/mcs.a003178.Full Text
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Dunn, Jessilyn, Ryan Runge, and Michael Snyder. “Wearables and the medical revolution.” Personalized Medicine 15, no. 5 (September 2018): 429–48. https://doi.org/10.2217/pme-2018-0044.Full Text Open Access Copy
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Kellogg, Ryan A., Jessilyn Dunn, and Michael P. Snyder. “Personal Omics for Precision Health.” Circulation Research 122, no. 9 (April 27, 2018): 1169–71. https://doi.org/10.1161/circresaha.117.310909.Full Text Open Access Copy
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Dunn, Jessilyn, Rachel Simmons, Salim Thabet, and Hanjoong Jo. “The role of epigenetics in the endothelial cell shear stress response and atherosclerosis.” The International Journal of Biochemistry & Cell Biology 67 (October 2015): 167–76. https://doi.org/10.1016/j.biocel.2015.05.001.Full Text
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Dunn, Jessilyn, Haiwei Qiu, Soyeon Kim, Daudi Jjingo, Ryan Hoffman, Chan Woo Kim, Inhwan Jang, et al. “Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis.” Journal of Clinical Investigation 124, no. 7 (July 1, 2014): 3187–99. https://doi.org/10.1172/jci74792.Full Text
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Annaluru, Narayana, Héloïse Muller, Leslie A. Mitchell, Sivaprakash Ramalingam, Giovanni Stracquadanio, Sarah M. Richardson, Jessica S. Dymond, et al. “Total Synthesis of a Functional Designer Eukaryotic Chromosome.” Science 344, no. 6179 (April 4, 2014): 55–58. https://doi.org/10.1126/science.1249252.Full Text
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Tarbell, John M., Zhong-Dong Shi, Jessilyn Dunn, and Hanjoong Jo. “Fluid Mechanics, Arterial Disease, and Gene Expression.” Annual Review of Fluid Mechanics 46, no. 1 (January 3, 2014): 591–614. https://doi.org/10.1146/annurev-fluid-010313-141309.Full Text
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Dunn, Jessilyn, Sarah Gutbrod, Alanah Webb, Alina Pak, Simran K. Jandu, Anil Bhunia, Dan E. Berkowitz, and Lakshmi Santhanam. “S-Nitrosation of arginase 1 requires direct interaction with inducible nitric oxide synthase.” Molecular and Cellular Biochemistry 355, no. 1–2 (September 2011): 83–89. https://doi.org/10.1007/s11010-011-0841-2.Full Text
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Santhanam, Lakshmi, Eric C. Tuday, Alanah K. Webb, Phillip Dowzicky, Jae Hyung Kim, Young Jun Oh, Gautam Sikka, et al. “Decreased S -Nitrosylation of Tissue Transglutaminase Contributes to Age-Related Increases in Vascular Stiffness.” Circulation Research 107, no. 1 (July 9, 2010): 117–25. https://doi.org/10.1161/circresaha.109.215228.Full Text
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Bent, Brinnae, Ida Sim, and Jessilyn P. Dunn. “Digital Medicine Community Perspectives and Challenges: Survey Study (Preprint),” n.d. https://doi.org/10.2196/preprints.24570.Full Text
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Bent, Brinnae, and Jessilyn P. Dunn. “Wearables in the SARS-CoV-2 Pandemic: What Are They Good for? (Preprint),” n.d. https://doi.org/10.2196/preprints.25137.Full Text
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Dunn, Jessilyn P., Marios Hadjimichael, Yuriy Isparyan, Diyalo Manral, and Ryan Runge. “MoveIt! Smartphone Application for Promoting Healthy Living,” n.d., 1–1.
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Dunn, Jessilyn, Salim Thabet, and Hanjoong Jo. “Flow-Dependent Epigenetic DNA Methylation in Endothelial Gene Expression and Atherosclerosis,” n.d., 9–9.
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Li, Xiao, Jessilyn Dunn, Denis Salins, Gao Zhou, Wenyu Zhou, Sophia Miryam Schüssler-Fiorenza Rose, Dalia Perelman, et al. “Digital Health: Tracking Physiomes and Activity Using Wearable Biosensors Reveals Useful Health-Related Information.” Plos Biology 15, no. 1 (n.d.): e2001402–e2001402. https://doi.org/10.1371/journal.pbio.2001402.Full Text Open Access Copy
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Yeh, Hugh, Jessilyn Dunn, Thomas Prieto, Franklin Luc, Srikanth Muppidi, Scott Delp, and Michael P. Snyder. “Consumer-grade wrist-worn PPG sensors can be used to detect differences in heart rate variability among a heterogeneous prediabetic population,” n.d., 1–1.
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- Teaching & Mentoring
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Recent Courses
- BME 590: Special Topics in Biomedical Engineering 2021
- BME 791: Graduate Independent Study 2021
- HLTHPOL 395: Bass Connections COVID-19 Research Team 2021
- HLTHPOL 795: Bass Connections COVID-19 Research Team 2021
- BME 493: Projects in Biomedical Engineering (GE) 2020
- BME 494: Projects in Biomedical Engineering (GE) 2020
- BME 590: Special Topics in Biomedical Engineering 2020
- BME 791: Graduate Independent Study 2020
- BME 792: Continuation of Graduate Independent Study 2020
- EGR 393: Research Projects in Engineering 2020
- HLTHPOL 395: Bass Connections COVID-19 Research Team 2020
- HLTHPOL 795: Bass Connections COVID-19 Research Team 2020
- BME 493: Projects in Biomedical Engineering (GE) 2019
- BME 494: Projects in Biomedical Engineering (GE) 2019
- BME 590: Special Topics in Biomedical Engineering 2019
- BME 791: Graduate Independent Study 2019
- Scholarly, Clinical, & Service Activities
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Outreach & Engaged Scholarship
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