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Readability of Pediatric Otolaryngology Information: Comparing AI-Generated Content With Google Search Results.

Journal article Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · December 2025 ObjectiveThis study evaluates and compares the readability of pediatric otolaryngology patient education materials generated by ChatGPT4o and those retrieved from Google searches. The goal is to determine whether artificial intelligence (AI)-gener ... Full text Cite

Factors influencing likelihood of inpatient frenotomy in newborns with ankyloglossia.

Journal article International journal of pediatric otorhinolaryngology · December 2025 ObjectiveThis study investigates national trends in inpatient frenotomy for newborns with ankyloglossia, focusing on the association between demographic, socioeconomic, and regional factors and the likelihood of undergoing the procedure.Method ... Full text Cite

Evaluating tracheostomy techniques in severe coronavirus disease 2019: open vs. percutaneous approaches.

Journal article The Journal of laryngology and otology · November 2025 ObjectivesThis study compares outcomes of open versus percutaneous tracheostomies in coronavirus disease 2019 patients to guide clinical decision-making based on disease severity.MethodsA retrospective cohort study using the 2020 National ... Full text Cite

Understanding Non-Attendance in Pediatric Otolaryngology: A Retrospective Study of Demographics, Socioeconomics, and Pandemic Effects.

Journal article The Annals of otology, rhinology, and laryngology · October 2025 ObjectiveThe objective of this study is to identify factors associated with missed pediatric otolaryngology appointments at a large safety net hospital, focusing on demographic, socioeconomic, COVID-related, and appointment-related factors.Met ... Full text Cite

Understanding paediatric laryngomalacia: a study of social determinants and associated diseases.

Journal article The Journal of laryngology and otology · June 2025 ObjectiveThis study investigated the influence of socioeconomic factors on the incidence of laryngomalacia in paediatric in-patients.MethodsData from the 2016 Healthcare Cost and Utilization Project Kid Inpatient Database were analysed. V ... Full text Cite

Funding, Publication Rate and Characteristics of Paediatric Sleep Apnea Clinical Trials: A Cross-Sectional Analysis.

Journal article Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · May 2025 ObjectiveThe objective of this study is to characterise available clinical trial information for paediatric obstructive sleep apnea (OSA) and identify opportunities for future research to better treat children with this condition.MethodsA ... Full text Cite

Pediatric Acute Otitis Media Clinical Trials: An Analysis of Diversity.

Journal article Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · April 2025 ObjectiveThis study aims to assess the diversity and equity of pediatric acute otitis media (AOM) trials using ClinicalTrials.gov, focusing on participant demographics and representation to identify gaps in inclusivity and inform strategies for pr ... Full text Cite

Seasonal and regional distribution of laryngomalacia in paediatric in-patients.

Journal article The Journal of laryngology and otology · March 2025 ObjectivesThis study investigates the seasonal and regional distribution of paediatric laryngomalacia admissions in the United States, hypothesizing higher admission rates in winter and colder regions due to reduced sunlight exposure affecting vit ... Full text Cite

Study Protocol Evaluating Breastfeeding for Mother-Infant Dyads Experiencing Infant Ankyloglossia.

Journal article Nursing research · March 2025 BackgroundTongue-tie is associated with nipple pain and early breastfeeding cessation. To date, research has been limited by small sample sizes and a dearth of evidence on the effects of tongue-tie on infant feeding symptoms and physiologic breast ... Full text Cite

Assessing the Efficacy of Acupuncture in the Treatment of Olfactory Dysfunction: A Systematic Review.

Journal article The Annals of otology, rhinology, and laryngology · February 2025 ObjectiveThis article seeks to systematically review existing literature on the use of acupuncture in treating olfactory dysfunction in order to better understand the methodology and efficacy of this alternative treatment modality.Methods ... Full text Cite

The Impact of COVID-19 and Socioeconomic Determinants on Appointment Non-Attendance in an Urban Otolaryngology Clinic: A Retrospective Analysis From a Safety Net Hospital.

Journal article The Annals of otology, rhinology, and laryngology · February 2025 ObjectiveThe objective of this study is to investigate various demographic, socioeconomic, COVID-related, and clinical factors associated with missed otolaryngology appointments in the outpatient setting at Boston Medical Center (BMC), an urban sa ... Full text Cite

Appointment Factors Contributing to Children with Speech Disorders Missing Speech and Language Pathology Appointments.

Journal article Clinical pediatrics · December 2024 This study explores missed pediatric speech and language pathology (SLP) appointments to identify barriers for patients with speech disorders. Data from 839 referrals at Boston Medical Center, including demographics, appointment details, COVID-19 lockdown, ... Full text Cite

AI-generated text in otolaryngology publications: a comparative analysis before and after the release of ChatGPT.

Journal article European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · November 2024 PurposeThis study delves into the broader implications of artificial intelligence (AI) text generation technologies, including large language models (LLMs) and chatbots, on the scientific literature of otolaryngology. By observing trends in AI-gen ... Full text Cite

Understanding pediatric inpatient conductive hearing loss: An analysis of patient demographics.

Journal article American journal of otolaryngology · November 2024 ObjectiveHearing loss is a common sensory impairment in children that affects quality of life and development. Early intervention, such as hearing aids and communication therapies, can help children overcome these challenges and lessen the impact ... Full text Cite

Navigating ChatGPT's alignment with expert consensus on pediatric OSA management.

Journal article International journal of pediatric otorhinolaryngology · November 2024 ObjectiveThis study aimed to evaluate the potential integration of artificial intelligence (AI), specifically ChatGPT, into healthcare decision-making, focusing on its alignment with expert consensus statements regarding the management of persiste ... Full text Cite

Factors influencing hospital charges for tonsillectomy to treat obstructive sleep apnea in children.

Journal article Sleep & breathing = Schlaf & Atmung · October 2024 PurposeThis study investigates the impact of patient characteristics and demographics on hospital charges for tonsillectomy as a treatment for pediatric obstructive sleep apnea (OSA). The aim is to identify potential disparities in hospital charge ... Full text Cite

Discrepancies in pediatric OSA surgery hospital stay length across regions.

Journal article International journal of pediatric otorhinolaryngology · September 2024 ObjectiveTo investigate regional disparities in the length of hospital stay (LOS) for pediatric patients undergoing tonsillectomy for obstructive sleep apnea (OSA) in the United States.MethodsWe utilized the Healthcare Cost and Utilizatio ... Full text Cite

Emerging Roles of Circular RNA in Macrophage Activation and Inflammatory Lung Responses.

Journal article Cells · August 2024 Circular RNA (circRNA) is a type of single-stranded RNA that forms a covalently closed continuous loop, unlike linear RNA. The expression of circRNAs in mammals is often conserved across species and shows tissue and cell specificity. Some circRNA serve as ... Full text Cite

Assessing ChatGPT's Responses to Otolaryngology Patient Questions.

Journal article The Annals of otology, rhinology, and laryngology · July 2024 ObjectiveThis study aims to evaluate ChatGPT's performance in addressing real-world otolaryngology patient questions, focusing on accuracy, comprehensiveness, and patient safety, to assess its suitability for integration into healthcare.Method ... Full text Cite

Extracellular Vesicles: An Emerging Clinical Opportunity in Musculoskeletal Disease.

Journal article Tissue engineering. Part B, Reviews · June 2024 Extracellular vesicles (EVs) are important mediators of cell-to-cell communication in the extracellular space. These membranous nanoparticles carry various molecules, often referred to as "cargo," which are delivered to nearby target cells. In the past dec ... Full text Cite

Speech Outcomes of Frenectomy for Tongue-Tie Release: A Systematic Review and Meta-Analysis.

Journal article The Annals of otology, rhinology, and laryngology · June 2024 ObjectiveTongue-tie, which is also known as ankyloglossia, is a common condition where the lingual frenulum is unusually tight or short. While most literature investigates the impact of tongue-tie on breastfeeding, recent articles have examined it ... Full text Cite

Comparison of ChatGPT knowledge against 2020 consensus statement on ankyloglossia in children.

Journal article International journal of pediatric otorhinolaryngology · May 2024 ObjectiveThis paper evaluates ChatGPT's accuracy and consistency in providing information on ankyloglossia, a congenital oral condition. Assessing alignment with expert consensus, the study explores potential implications for patients relying on A ... Full text Cite

Advances in the Use of Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Persistent Obstructive Sleep Apnea-A Systematic Review.

Journal article The Annals of otology, rhinology, and laryngology · March 2024 IntroductionThe Hypoglossal Nerve Stimulator (HNS) is a novel therapy that has been extensively studied in adults and more recently, it has been incorporated in children with Down Syndrome (DS) with persistent obstructive sleep apnea after adenoto ... Full text Cite

Patient characteristics of pediatric inpatients with sensorineural hearing loss: Insights from the 2016 KID database.

Journal article American journal of otolaryngology · January 2024 This study examines how patient demographics impact pediatric sensorineural hearing loss (SNHL) prevalence using the 2016 Kids' Inpatient Database (KID). By analyzing age, gender, race, income, insurance, and region, the study provides insights for early i ... Full text Cite

Exploring the appointment factors affecting pediatric patients with swallow disorders: Implications for speech and language pathology attendance.

Journal article International journal of pediatric otorhinolaryngology · December 2023 IntroductionFeeding and swallowing disorders have become increasingly prevalent among children, necessitating effective management to prevent long-term complications. Speech and language pathology (SLP) services play a crucial role in diagnosing a ... Full text Cite

Artificial Intelligence in Orthopaedic Surgery: Can a Large Language Model "Write" a Believable Orthopaedic Journal Article?

Journal article The Journal of bone and joint surgery. American volume · September 2023 Abstract➢ Natural language processing with large language models is a subdivision of artificial intelligence (AI) that extracts meaning from text with use of linguistic rules, statistics, and machine learning to generate appropriate text responses ... Full text Cite

An Analysis of Laryngomalacia and Its Interplay With Obesity and Obstructive Sleep Apnea in Pediatric Inpatients.

Journal article Cureus · September 2023 Objective  This study aimed to investigate the potential relationship between laryngomalacia and obesity as well as explore the interplay between laryngomalacia and obstructive sleep apnea using the Kids' Inpatient Database (KID) for the year 2016. Methods ... Full text Cite

The effect of frenectomy for tongue-tie, lip-tie, or cheek-tie on breastfeeding outcomes: A systematic review of articles over time and suggestions for management.

Journal article International journal of pediatric otorhinolaryngology · August 2023 ObjectiveTongue-tie, or ankyloglossia, is a common condition characterized by an abnormally short or tight lingual frenulum and is known to cause breastfeeding difficulties, leading to damage to the nipple, early discontinuation of breastfeeding, ... Full text Cite

Bacterial Outer Membrane Vesicles Promote Lung Inflammatory Responses and Macrophage Activation via Multi-Signaling Pathways.

Journal article Biomedicines · February 2023 Emerging evidence suggests that Gram-negative bacteria release bacterial outer membrane vesicles (OMVs) and that these play an important role in the pathogenesis of bacterial infection-mediated inflammatory responses and organ damage. Despite the fact that ... Full text Cite

The Role of Extracellular Vesicles in Diseases of the Ear, Nose, and Throat.

Journal article Medical sciences (Basel, Switzerland) · December 2022 Extracellular vesicles (EVs) are membranous nanoparticles produced by most cell types into the extracellular space and play an important role in cell-to-cell communication. Historically, EVs were categorized based on their methods of biogenesis and size in ... Full text Cite

Microvesicle-Derived miRNAs Regulate Proinflammatory Macrophage Activation in the Lung Following Ozone Exposure.

Journal article Toxicological sciences : an official journal of the Society of Toxicology · April 2022 Ozone is a ubiquitous air pollutant that causes lung damage and altered functioning. Evidence suggests that proinflammatory macrophages contribute to ozone toxicity. Herein, we analyzed the role of extracellular vesicles (EVs) and microRNA (miRNA) cargo in ... Full text Cite

Extracellular vesicles in respiratory disease.

Book section · January 2022 Extracellular vesicles (EVs) are membranous nanoparticles secreted by nearly all cell types and play a critical role in cell-to-cell crosstalk. EVs can be categorized based on their size, surface markers, or the cell type from which they originate. EVs car ... Full text Cite

Low concentration of polyethylene glycol facilitates separation of extracellular vesicles from bronchoalveolar lavage fluid.

Journal article American journal of physiology. Lung cellular and molecular physiology · April 2021 Extracellular vesicles (EVs) in bodily fluids play an essential role in cell-cell cross talk and potentially serve as novel biomarkers in "liquid biopsy." It is crucial to have a consistent, efficient, and reliable method to separate EVs from bodily fluids ... Full text Cite

Extracellular Vesicles: A Novel Opportunity for Precision Medicine in Respiratory Diseases.

Journal article Frontiers in medicine · January 2021 Extracellular vesicles are membrane-bound nanoparticles secreted by cells which play a well-known role in cell to cell communication. The most update to date nomenclature categorizes extracellular vesicles based on their relative size, protein markers, and ... Full text Cite

The Evolving Role of Caveolin-1: A Critical Regulator of Extracellular Vesicles.

Journal article Medical sciences (Basel, Switzerland) · November 2020 Emerging evidence suggests that extracellular vesicles (EVs) play an essential role in mediating intercellular communication and inter-organ crosstalk both at normal physiological conditions and in the pathogenesis of human diseases. EV cargos are made up ... Full text Cite

Pretreated household materials carry similar filtration protection against pathogens when compared with surgical masks.

Journal article American journal of infection control · August 2020 ObjectiveThe past 4 months, the emergence and spread of novel 2019 SARS-Cov-2 (COVID-19) has led to a global pandemic which is rapidly depleting supplies of personal protective equipment worldwide. There are currently over 1.6 million confirmed ca ... Full text Cite

Single-step RT-qPCR for detection of extracellular vesicle microRNAs in vivo: a time- and cost-effective method.

Journal article American journal of physiology. Lung cellular and molecular physiology · April 2020 Emerging evidence suggests that extracellular vesicle (EV)-associated microRNAs (miRNAs) are a potential diagnostic tool for liquid biopsy in various human diseases. However, the experimental procedure for the detection of EV-associated miRNAs (EV-miRNAs) ... Full text Cite

Post-translational Modification Regulates Formation and Cargo-Loading of Extracellular Vesicles.

Journal article Frontiers in immunology · January 2020 Accumulating evidence suggests that post-translational modifications (PTMs) regulate the selective encapsulation of non-coding RNA molecules into extracellular vesicles (EVs) and contribute to the downstream functions of EVs or EV-cargo non-coding RNAs. EV ... Full text Cite

Extracellular vesicle-cargo miR-185-5p reflects type II alveolar cell death after oxidative stress.

Journal article Cell death discovery · January 2020 Acute respiratory distress syndrome (ARDS) is a devastating syndrome responsible for significant morbidity and mortality. Diffuse alveolar epithelial cell death, including but not limited to apoptosis and necroptosis, is one of the hallmarks of ARDS. Curre ... Full text Cite

Isolation and characterization of extracellular vesicles from Broncho-alveolar lavage fluid: a review and comparison of different methods.

Journal article Respiratory research · October 2019 Extracellular vesicles (EVs) are cell-derived membranous vesicles secreted by cells into the extracellular space, which play a role in cell to cell communication. EVs are categorized into 3 groups depending on their size, surface marker, and method of rele ... Full text Cite

Extracellular Vesicle-Shuttling MicroRNAs Regulate the Development of Inflammatory Lung Responses.

Journal article Annals of pulmonary and critical care medicine · October 2018 MicroRNAs are small single-stranded, non-coding RNAs which have a known role in post-transcriptional regulation of gene expression. Recent studies have reported that extracellular vesicles are capable of specific delivery of miRNAs to a target cell or tiss ... Cite