Skip to main content

Josh Huang

Morris N. Broad Distinguished Professor of Neurobiology
Neurobiology
311 Research Drive, Box 3209, Durham, NC 27710
311 Research Drive, Box 3209, Durham, NC 27710

Scholarly Works - Preprints


Motor Cortical Output Integrates Distorted Proprioceptive Feedback.

Preprint · November 13, 2025 Proprioceptive feedback from muscles is essential for continuous monitoring and precise control of limb movement, yet how such peripheral feedback is integrated into ongoing descending motor cortical dynamics remains largely unclear. Here we used precisely ... Full text Link to item Cite

RNA-programmable cell type monitoring and manipulation in the human cortex with CellREADR.

Preprint · May 9, 2025 Reliable and systematic access to diverse cell types is necessary for understanding the organization, function, and pathophysiology of human neural circuits. Methods for targeting human neural populations are scarce and currently center on identifying tran ... Full text Link to item Cite

Cortico-thalamic communication for action coordination in a skilled motor sequence.

Preprint · October 30, 2024 The coordination of forelimb and orofacial movements to compose an ethological reach-to-consume behavior likely involves neural communication across brain regions. Leveraging wide-field imaging and photo-inhibition to survey across the cortex, we identifie ... Full text Link to item Cite

A cortical circuit for orchestrating oromanual food manipulation

Preprint · 2022 ABSTRACT The seamless coordination of hands and mouth—whether in humans eating corn on the cob or mice extracting sunflower seeds—represents one of evolution’s most sophisticated motor achievements. Whereas spinal and brainstem circuits implement ... Full text Cite

An integrated transcriptomic and epigenomic atlas of mouse primary motor cortex cell types

Preprint · 2020 Single cell transcriptomics has transformed the characterization of brain cell identity by providing quantitative molecular signatures for large, unbiased samples of brain cell populations. With the proliferation of taxonomies based on individual datasets, ... Full text Cite