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Kirubel Asfaw

Bioinformatician, Senior
Duke Clinical Research Institute
DUMC 104028, Durham, NC 27710
DCRI, 200 Morris Street, Durham, NC 27701

Scholarly Works


Clinical Patterns and Appropriateness of Apixaban Dosing in Patients With Atrial Fibrillation.

Journal article JACC Adv · June 29, 2026 BACKGROUND: Apixaban is a direct oral anticoagulant for stroke prevention in patients with atrial fibrillation (AF) or atrial flutter (AFL), with dose reduction being recommended based on age, body weight, and creatinine. OBJECTIVES: The objective of the s ... Full text Link to item Cite

Predictors of ischemic stroke and major bleeding among patients with atrial fibrillation in clinical practice.

Journal article Am Heart J · May 19, 2026 BACKGROUND: Numerous risk scores exist to quantify the risk of ischemic stroke risk in patients with atrial fibrillation or flutter (AF/AFL). However, how these tools perform in cohorts or those already on oral anticoagulation (OAC) therapy is unclear. MET ... Full text Link to item Cite

The CHI-RON Study: Using PCORnet® and Patient Engagement Strategies to Improve Diversity Among Research Participants in the Congenital Heart Initiative.

Journal article Med Care · February 1, 2026 BACKGROUND: The Congenital Heart Initiative-Redefining Outcomes and Navigation to Adult-Centered Care (CHI-RON) study is a unique collaboration between the PCORnet and Congenital Heart Initiative (CHI), the first patient powered registry for adult congenit ... Full text Link to item Cite

Abstract 4360264: Real World Evaluation of the Eligibility, Uptake, and Cardiometabolic Effects of Tirzepatide: An Analysis from the Platform for Evidence GeneraTion in CArdiometabolic HeaLth (PETAL) Study

Conference Circulation · November 4, 2025 Background: Tirzepatide is a dual glucose-dependent insulinotropic polypeptide and glucagon like peptide-1 receptor agonist that has been shown to have cardiometabolic benefits. Howeve ... Full text Cite

Concordance Between Survey and Electronic Health Record Data in the COVID-19 Citizen Science Study: Retrospective Cohort Analysis.

Journal article JMIR Form Res · July 28, 2025 BACKGROUND: Real-world data reported by patients and extracted from electronic health records (EHRs) are increasingly leveraged for research, policy, and clinical decision-making. However, it is not always obvious the extent to which these 2 data sources a ... Full text Link to item Cite