Kyle Walsh
Associate Professor in Neurosurgery
Dr. Walsh is Associate Professor of Neurosurgery and Pathology, Director of the Division of Neuro-epidemiology, and a Senior Fellow in the Duke Center for the Study of Aging and Human Development. He leads Duke’s Neuro-epidemiology Lab, which integrates bench science with statistical methods to study the neurobiology of glial senescence and gliomagenesis. This research interrogates human genomic and epigenomic profiles to identify both heritable and modifiable factors that contribute to neurologic and physical decline, applying these approaches to studying the shared neurobiology of cognition, glial senescence, and gliomagenesis. The lab has a long history studying telomere maintenance in pre-malignant cells and its role in the development of cancer, most notably glioblastoma.
Current Appointments & Affiliations
- Associate Professor in Neurosurgery, Neurosurgery, Neurosurgery 2021
- Associate Professor in Pathology, Pathology, Clinical Science Departments 2020
- Associate Professor in Pediatrics, Pediatrics, Children's Health Discovery Institute, Pediatrics 2020
- Associate Professor in Population Health Sciences, Population Health Sciences, Basic Science Departments 2020
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2017
Contact Information
- 571 Research Drive, Msrb-1, Rm 442, Durham, NC 27710
- DUMC Box 3050, Durham, NC 27710
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kyle.walsh@duke.edu
(919) 684-8732
- Background
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Education, Training, & Certifications
- Ph.D., Yale University School of Medicine 2011
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Previous Appointments & Affiliations
- Associate Professor of Neurosurgery, Neurosurgery, Neurosurgery 2017 - 2020
- Associate Professor in Population Health Sciences, Population Health Sciences, Basic Science Departments 2018 - 2020
- Associate Professor in Pediatrics, Pediatrics, Children's Health Discovery Institute, Pediatrics 2018 - 2020
- Associate Professor in Pathology, Pathology, Clinical Science Departments 2018 - 2020
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Leadership & Clinical Positions at Duke
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Director, Division of Neuro-epidemiology
Co-leader, DCI Neuro-Oncology Research Program
Genes and Biology Leader, Children's Health and Discovery Institute
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Director, Division of Neuro-epidemiology
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Academic Positions Outside Duke
- Assistant Professor of Neurological Surgery, University of California, San Francisco. 2013 - 2017
- Recognition
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In the News
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AUG 3, 2022 Duke Health News -
NOV 19, 2021 Duke Health News -
FEB 22, 2021 Duke Health News
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- Expertise
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Subject Headings
- Research
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Selected Grants
- NINDS Research Education Programs for Residents and Fellows in Neurosurgery awarded by National Institutes of Health 2009 - 2025
- Viral Oncology Training Grant awarded by National Institutes of Health 1980 - 2024
- 6-Thio-Deoxyguanosine: A novel telomerase-mediated therapy for oligodendroglioma linking cell-intrinsic DNA damage to immune activation awarded by Oligo Nation 2021 - 2023
- Characterizing germline and somatic alterations by glioma subtypes and clinical outcome awarded by Stanford University 2022 - 2023
- Genomic and Epigenomic Blood sample Analysis for FIG Study awarded by Olivia Newton-John Cancer Research Institute 2021 - 2022
- Identifying transplacental correlates of protection against congenital CMV transmission awarded by Moderna Therapeutics, Inc. 2021 - 2022
- Immune Correlates and Mechanisms of Perinatal Cytomegalovirus Infection and Later lLife ALL Development awarded by National Institutes of Health 2019 - 2022
- Serologic and genomic modifiers of beta-amyloid levels in an immuno-compromised cohort of adult Down syndrome patients awarded by Infectious Diseases Society of America 2021 - 2022
- The role of rare and common variants in genetic predisposition to medulloblastoma awarded by Sontag Foundation 2017 - 2021
- Genetic Susceptibility to Pediatric Glioma in Individuals and Diverse populations awarded by University of Southern California 2019 - 2021
- 2020 Pediatric Oncology Student Training (POST) Program awarded by Alex's Lemonade Stand 2020
- My Childhood Cancer: Survey Series awarded by Alex's Lemonade Stand 2018 - 2020
- Genetic Susceptibility to pediatric Osteosarcoma and Interaction with Measures of Childhood Growth awarded by Alex's Lemonade Stand 2017 - 2018
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External Relationships
- BP America, Inc
- John Wiley & Sons, Inc.
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Davis, Elizabeth S., Courtney E. Wimberly, Lisa Towry, Emily E. Johnston, and Kyle M. Walsh. “Financial hardships and psychosocial outcomes among parents of children who die of cancer.” Pediatr Blood Cancer 70, no. 2 (February 2023): e30066. https://doi.org/10.1002/pbc.30066.Full Text Link to Item
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Yuile, Alexander, Mustafa Khasraw, Justin T. Low, Kyle M. Walsh, Eric Lipp, Joanne Sy, Laveniya Satgunaseelan, et al. “Patterns of care in adult histone mutant gliomas: Results of an international survey.” Neurooncol Pract 9, no. 6 (December 2022): 520–25. https://doi.org/10.1093/nop/npac047.Full Text Link to Item
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Khaire, Archita S., Courtney E. Wimberly, Eleanor C. Semmes, Jillian H. Hurst, and Kyle M. Walsh. “An integrated genome and phenome-wide association study approach to understanding Alzheimer's disease predisposition.” Neurobiol Aging 118 (October 2022): 117–23. https://doi.org/10.1016/j.neurobiolaging.2022.05.011.Full Text Link to Item
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Li, Shaobo, Charleston W. K. Chiang, Swe Swe Myint, Katti Arroyo, Tsz Fung Chan, Libby Morimoto, Catherine Metayer, Adam J. de Smith, Kyle M. Walsh, and Joseph L. Wiemels. “Localized variation in ancestral admixture identifies pilocytic astrocytoma risk loci among Latino children.” Plos Genet 18, no. 9 (September 2022): e1010388. https://doi.org/10.1371/journal.pgen.1010388.Full Text Link to Item
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Semmes, Eleanor C., Itzayana G. Miller, Courtney E. Wimberly, Caroline T. Phan, Jennifer A. Jenks, Melissa J. Harnois, Stella J. Berendam, et al. “Maternal Fc-mediated non-neutralizing antibody responses correlate with protection against congenital human cytomegalovirus infection.” J Clin Invest 132, no. 16 (August 15, 2022). https://doi.org/10.1172/JCI156827.Full Text Open Access Copy Link to Item
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Gulrajani, Natalie B., Samuel Montes, Daniel McGough, Courtney E. Wimberly, Ameera Khattab, Eleanor C. Semmes, Lisa Towry, et al. “Assisted reproductive technology and association with childhood cancer subtypes.” Cancer Med, August 5, 2022. https://doi.org/10.1002/cam4.5114.Full Text Link to Item
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Byun, Jinyoung, Younghun Han, Yafang Li, Jun Xia, Erping Long, Jiyeon Choi, Xiangjun Xiao, et al. “Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer.” Nat Genet 54, no. 8 (August 2022): 1167–77. https://doi.org/10.1038/s41588-022-01115-x.Full Text Link to Item
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Walsh, Kyle M., Corey Neff, Melissa L. Bondy, Carol Kruchko, Jason T. Huse, Christopher I. Amos, Jill S. Barnholtz-Sloan, and Quinn T. Ostrom. “Influence of county-level geographic/ancestral origin on glioma incidence and outcomes in US Hispanics.” Neuro Oncol, July 22, 2022. https://doi.org/10.1093/neuonc/noac175.Full Text Link to Item
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Xu, Keren, Shaobo Li, Ivo S. Muskens, Natalina Elliott, Swe Swe Myint, Priyatama Pandey, Helen M. Hansen, et al. “Accelerated epigenetic aging in newborns with Down syndrome.” Aging Cell 21, no. 7 (July 2022): e13652. https://doi.org/10.1111/acel.13652.Full Text Link to Item
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Wimberly, Courtney E., Lisa Towry, Elizabeth Davis, Emily E. Johnston, and Kyle M. Walsh. “SARS-CoV-2 vaccine acceptability among caregivers of childhood cancer survivors.” Pediatr Blood Cancer 69, no. 6 (June 2022): e29443. https://doi.org/10.1002/pbc.29443.Full Text Link to Item
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Semmes, Eleanor C., Shuk Hang Li, Jillian H. Hurst, Zidanyue Yang, Donna Niedzwiecki, Genevieve G. Fouda, Joanne Kurtzberg, Kyle M. Walsh, and Sallie R. Permar. “Congenital Human Cytomegalovirus Infection Is Associated With Decreased Transplacental IgG Transfer Efficiency Due to Maternal Hypergammaglobulinemia.” Clin Infect Dis 74, no. 7 (April 9, 2022): 1131–40. https://doi.org/10.1093/cid/ciab627.Full Text Open Access Copy Link to Item
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Qian, Danwen, Hongliang Liu, Lingling Zhao, Sheng Luo, Kyle M. Walsh, Jiaoti Huang, Chuan-Yuan Li, and Qingyi Wei. “A pleiotropic ATM variant (rs1800057 C>G) is associated with risk of multiple cancers.” Carcinogenesis 43, no. 1 (February 11, 2022): 60–66. https://doi.org/10.1093/carcin/bgab092.Full Text Open Access Copy Link to Item
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Byun, Jinyoung, Younghun Han, Kyle M. Walsh, Amy S. Park, Melissa L. Bondy, and Christopher I. Amos. “Shared genomic architecture between COVID-19 severity and numerous clinical and physiologic parameters revealed by LD score regression analysis.” Sci Rep 12, no. 1 (February 3, 2022): 1891. https://doi.org/10.1038/s41598-022-05832-5.Full Text Link to Item
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Kachuri, Linda, and Kyle M. Walsh. “Long telomeres in need of a SNP: Germline contributions of telomere maintenance to glioma.” Neuro Oncol 24, no. 2 (February 1, 2022): 182–83. https://doi.org/10.1093/neuonc/noab260.Full Text Link to Item
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Price, Meghan J., Rafael De la Garza Ramos, Tara Dalton, Edwin McCray, Zach Pennington, Melissa Erickson, Kyle M. Walsh, et al. “Insurance status as a mediator of clinical presentation, type of intervention, and short-term outcomes for patients with metastatic spine disease.” Cancer Epidemiol 76 (February 2022): 102073. https://doi.org/10.1016/j.canep.2021.102073.Full Text Link to Item
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Li, Shaobo, Xiaowu Gai, Swe Swe Myint, Katti Arroyo, Libby Morimoto, Catherine Metayer, Adam J. de Smith, Kyle M. Walsh, and Joseph L. Wiemels. “Mitochondrial 1555 G>A variant as a potential risk factor for childhood glioblastoma.” Neurooncol Adv 4, no. 1 (2022): vdac045. https://doi.org/10.1093/noajnl/vdac045.Full Text Link to Item
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Walsh, Kyle M., Chenan Zhang, Lisa Calvocoressi, Helen M. Hansen, Andrew Berchuck, Joellen M. Schildkraut, Melissa L. Bondy, Margaret Wrensch, Joseph L. Wiemels, and Elizabeth B. Claus. “Pleiotropic MLLT10 variation confers risk of meningioma and estrogen-mediated cancers.” Neurooncol Adv 4, no. 1 (2022): vdac044. https://doi.org/10.1093/noajnl/vdac044.Full Text Open Access Copy Link to Item
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Yu, Shengnan, Shiyou Wei, Milan Savani, Xiang Lin, Kuang Du, Ilgen Mender, Silvia Siteni, et al. “A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas.” Clin Cancer Res 27, no. 24 (December 15, 2021): 6800–6814. https://doi.org/10.1158/1078-0432.CCR-21-0374.Full Text Link to Item
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Pettit, Rowland W., Jinyoung Byun, Younghun Han, Quinn T. Ostrom, Jacob Edelson, Kyle M. Walsh, Melissa L. Bondy, Rayjean J. Hung, James D. McKay, and Christopher I. Amos. “The shared genetic architecture between epidemiological and behavioral traits with lung cancer.” Sci Rep 11, no. 1 (September 2, 2021): 17559. https://doi.org/10.1038/s41598-021-96685-x.Full Text Link to Item
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Ostrom, Quinn T., Jacob Edelson, Jinyoung Byun, Younghun Han, Ben Kinnersley, Beatrice Melin, Richard S. Houlston, et al. “Partitioned glioma heritability shows subtype-specific enrichment in immune cells.” Neuro Oncol 23, no. 8 (August 2, 2021): 1304–14. https://doi.org/10.1093/neuonc/noab072.Full Text Link to Item
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Byun, Jinyoung, Younghun Han, Quinn T. Ostrom, Jacob Edelson, Kyle M. Walsh, Rowland W. Pettit, Melissa L. Bondy, et al. “The Shared Genetic Architectures Between Lung Cancer and Multiple Polygenic Phenotypes in Genome-Wide Association Studies.” Cancer Epidemiol Biomarkers Prev 30, no. 6 (June 2021): 1156–64. https://doi.org/10.1158/1055-9965.EPI-20-1635.Full Text Link to Item
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Wimberly, Courtney E., Lisa Towry, Caroline Caudill, Emily E. Johnston, and Kyle M. Walsh. “Impacts of COVID-19 on caregivers of childhood cancer survivors.” Pediatr Blood Cancer 68, no. 4 (April 2021): e28943. https://doi.org/10.1002/pbc.28943.Full Text Link to Item
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Muskens, Ivo S., Shaobo Li, Thomas Jackson, Natalina Elliot, Helen M. Hansen, Swe Swe Myint, Priyatama Pandey, et al. “The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis.” Nat Commun 12, no. 1 (February 5, 2021): 821. https://doi.org/10.1038/s41467-021-21064-z.Full Text Link to Item
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Hendrix, James A., Angelika Amon, Leonard Abbeduto, Stamatis Agiovlasitis, Tarek Alsaied, Heather A. Anderson, Lisa J. Bain, et al. “Opportunities, barriers, and recommendations in down syndrome research.” Transl Sci Rare Dis 5, no. 3–4 (2021): 99–129. https://doi.org/10.3233/trd-200090.Full Text Link to Item
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Gulrajani, Natalie, Samuel Montes, Dan McGough, Courtney Wimberly, Ameera Khattab, Eleanor Semmes, Lisa Towry, et al. “Assisted reproductive technology and association with childhood cancer subtypes,” 2021. https://doi.org/10.1101/2021.04.26.21256117.Full Text
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Semmes, Eleanor, Itzayana Miller, Jennifer Jenks, Courtney Wimberly, Stella Berendam, Melissa Harnois, Helen Webster, et al. “Maternal Fc-mediated non-neutralizing antibody responses correlate with protection against congenital human cytomegalovirus infection,” 2021. https://doi.org/10.1101/2021.12.05.21267312.Full Text Open Access Copy
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Shen, Erica, Amanda E. D. Van Swearingen, Meghan J. Price, Ketan Bulsara, Roeland G. W. Verhaak, César Baëta, Brice D. Painter, et al. “A Need for More Molecular Profiling in Brain Metastases.” Front Oncol 11 (2021): 785064. https://doi.org/10.3389/fonc.2021.785064.Full Text Link to Item
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Zhao, Lingling, Hongliang Liu, Sheng Luo, Patricia G. Moorman, Kyle M. Walsh, Wei Li, and Qingyi Wei. “Associations between genetic variants of KIF5B, FMN1, and MGAT3 in the cadherin pathway and pancreatic cancer risk.” Cancer Med 9, no. 24 (December 2020): 9620–31. https://doi.org/10.1002/cam4.3603.Full Text Open Access Copy Link to Item
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Khasraw, Mustafa, Kyle M. Walsh, Amy B. Heimberger, and David M. Ashley. “What is the Burden of Proof for Tumor Mutational Burden in gliomas?” Neuro Oncol 23, no. 1 (November 30, 2020): 17–22. https://doi.org/10.1093/neuonc/noaa256.Full Text Link to Item
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Zhang, Chenan, Quinn T. Ostrom, Helen M. Hansen, Julio Gonzalez-Maya, Donglei Hu, Elad Ziv, Libby Morimoto, et al. “European genetic ancestry associated with risk of childhood ependymoma.” Neuro Oncol 22, no. 11 (November 26, 2020): 1637–46. https://doi.org/10.1093/neuonc/noaa130.Full Text Link to Item
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Broom, Alex, Katherine Kenny, Alexander Page, Nicole Cort, Eric S. Lipp, Aaron C. Tan, David M. Ashley, Kyle M. Walsh, and Mustafa Khasraw. “The Paradoxical Effects of COVID-19 on Cancer Care: Current Context and Potential Lasting Impacts.” Clin Cancer Res 26, no. 22 (November 15, 2020): 5809–13. https://doi.org/10.1158/1078-0432.CCR-20-2989.Full Text Link to Item
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Semmes, Eleanor C., Erica Shen, Jennifer L. Cohen, Chenan Zhang, Qingyi Wei, Jillian H. Hurst, and Kyle M. Walsh. “Genetic variation associated with childhood and adult stature and risk of MYCN-amplified neuroblastoma.” Cancer Med 9, no. 21 (November 2020): 8216–25. https://doi.org/10.1002/cam4.3458.Full Text Open Access Copy Link to Item
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Shen, Erica, Joanne Xiu, Rex Bentley, Giselle Y. López, and Kyle M. Walsh. “Frequent Mutations of POT1 Distinguish Pulmonary Sarcomatoid Carcinoma From Other Lung Cancer Histologies.” Clin Lung Cancer 21, no. 6 (November 2020): e523–27. https://doi.org/10.1016/j.cllc.2020.04.002.Full Text Link to Item
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Zhang, Chenan, Quinn T. Ostrom, Eleanor C. Semmes, Vijay Ramaswamy, Helen M. Hansen, Libby Morimoto, Adam J. de Smith, et al. “Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma.” Acta Neuropathol Commun 8, no. 1 (October 28, 2020): 173. https://doi.org/10.1186/s40478-020-01038-w.Full Text Link to Item
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Semmes, Eleanor C., Jillian H. Hurst, Kyle M. Walsh, and Sallie R. Permar. “Cytomegalovirus as an immunomodulator across the lifespan.” Curr Opin Virol 44 (October 2020): 112–20. https://doi.org/10.1016/j.coviro.2020.07.013.Full Text Link to Item
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Shen, Erica, Joanne Xiu, Giselle Y. Lopez, Rex Bentley, Ali Jalali, Amy B. Heimberger, Matthew N. Bainbridge, Melissa L. Bondy, and Kyle M. Walsh. “POT1 mutation spectrum in tumour types commonly diagnosed among POT1-associated hereditary cancer syndrome families.” J Med Genet 57, no. 10 (October 2020): 664–70. https://doi.org/10.1136/jmedgenet-2019-106657.Full Text Link to Item
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Liu, Xiaowen, Danwen Qian, Hongliang Liu, James L. Abbruzzese, Sheng Luo, Kyle M. Walsh, and Qingyi Wei. “Genetic variants of the peroxisome proliferator-activated receptor (PPAR) signaling pathway genes and risk of pancreatic cancer.” Mol Carcinog 59, no. 8 (August 2020): 930–39. https://doi.org/10.1002/mc.23208.Full Text Open Access Copy Link to Item
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Semmes, Eleanor C., Jayaram Vijayakrishnan, Chenan Zhang, Jillian H. Hurst, Richard S. Houlston, and Kyle M. Walsh. “Leveraging Genome and Phenome-Wide Association Studies to Investigate Genetic Risk of Acute Lymphoblastic Leukemia.” Cancer Epidemiol Biomarkers Prev 29, no. 8 (August 2020): 1606–14. https://doi.org/10.1158/1055-9965.EPI-20-0113.Full Text Link to Item
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Muskens, Ivo S., Adam J. de Smith, Chenan Zhang, Helen M. Hansen, Libby Morimoto, Catherine Metayer, Xiaomei Ma, Kyle M. Walsh, and Joseph L. Wiemels. “Germline cancer predisposition variants and pediatric glioma: a population-based study in California.” Neuro Oncol 22, no. 6 (June 9, 2020): 864–74. https://doi.org/10.1093/neuonc/noaa014.Full Text Link to Item
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Walsh, Kyle M. “Telomere Attrition in Childhood Cancer Survivors.” Clin Cancer Res 26, no. 10 (May 15, 2020): 2281–83. https://doi.org/10.1158/1078-0432.CCR-20-0380.Full Text Link to Item
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Winer, Peleg, Ivo S. Muskens, Kyle M. Walsh, Ajay Vora, Anthony V. Moorman, Joseph L. Wiemels, Irene Roberts, Anindita Roy, and Adam J. de Smith. “Germline variants in predisposition genes in children with Down syndrome and acute lymphoblastic leukemia.” Blood Adv 4, no. 4 (February 25, 2020): 672–75. https://doi.org/10.1182/bloodadvances.2019001216.Full Text Link to Item
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Zhao, Ling-Ling, Hong-Liang Liu, Sheng Luo, Kyle M. Walsh, Wei Li, and Qingyi Wei. “Associations of novel variants in PIK3C3, INSR and MAP3K4 of the ATM pathway genes with pancreatic cancer risk.” Am J Cancer Res 10, no. 7 (2020): 2128–44.Open Access Copy Link to Item
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Muskens, Ivo S., Qianxi Feng, Stephen S. Francis, Kyle M. Walsh, Roberta Mckean-Cowdin, William J. Gauderman, Adam J. de Smith, and Joseph L. Wiemels. “Pediatric glioma and medulloblastoma risk and population demographics: a Poisson regression analysis.” Neurooncol Adv 2, no. 1 (2020): vdaa089. https://doi.org/10.1093/noajnl/vdaa089.Full Text Link to Item
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Zhang, Chenan, Helen M. Hansen, Eleanor C. Semmes, Julio Gonzalez-Maya, Libby Morimoto, Qingyi Wei, William C. Eward, et al. “Common genetic variation and risk of osteosarcoma in a multi-ethnic pediatric and adolescent population.” Bone 130 (January 2020): 115070. https://doi.org/10.1016/j.bone.2019.115070.Full Text Link to Item
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Muskens, Ivo S., Chenan Zhang, Adam J. de Smith, Jaclyn A. Biegel, Kyle M. Walsh, and Joseph L. Wiemels. “Germline genetic landscape of pediatric central nervous system tumors.” Neuro Oncol 21, no. 11 (November 4, 2019): 1376–88. https://doi.org/10.1093/neuonc/noz108.Full Text Link to Item
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Smith, Adam J. de, Kyle M. Walsh, Libby M. Morimoto, Stephen S. Francis, Helen M. Hansen, Soyoung Jeon, Semira Gonseth, et al. “Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome.” Leukemia 33, no. 11 (November 2019): 2746–51. https://doi.org/10.1038/s41375-019-0514-9.Full Text Link to Item
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Brown, Austin L., Adam J. de Smith, Vincent U. Gant, Wenjian Yang, Michael E. Scheurer, Kyle M. Walsh, Jonathan M. Chernus, et al. “Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome.” Blood 134, no. 15 (October 10, 2019): 1227–37. https://doi.org/10.1182/blood.2018890764.Full Text Link to Item
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Smith, Adam J. de, Geneviève Lavoie, Kyle M. Walsh, Sumeet Aujla, Erica Evans, Helen M. Hansen, Ivan Smirnov, et al. “Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children.” Genes Chromosomes Cancer 58, no. 10 (October 2019): 723–30. https://doi.org/10.1002/gcc.22765.Full Text Link to Item
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Xu, Xinyuan, Danwen Qian, Hongliang Liu, Diana Cruz, Sheng Luo, Kyle M. Walsh, James L. Abbruzzese, Xuefeng Zhang, and Qingyi Wei. “Genetic variants in the liver kinase B1-AMP-activated protein kinase pathway genes and pancreatic cancer risk.” Mol Carcinog 58, no. 8 (August 2019): 1338–48. https://doi.org/10.1002/mc.23018.Full Text Open Access Copy Link to Item
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Walsh, Kyle M., and Elizabeth B. Claus. “Diet and risk of glioma: targets for prevention remain elusive.” Neuro Oncol 21, no. 7 (July 11, 2019): 832–33. https://doi.org/10.1093/neuonc/noz074.Full Text Link to Item
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Feng, Yun, Hongliang Liu, Bensong Duan, Zhensheng Liu, James Abbruzzese, Kyle M. Walsh, Xuefeng Zhang, and Qingyi Wei. “Potential functional variants in SMC2 and TP53 in the AURORA pathway genes and risk of pancreatic cancer.” Carcinogenesis 40, no. 4 (June 10, 2019): 521–28. https://doi.org/10.1093/carcin/bgz029.Full Text Open Access Copy Link to Item
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Yang, Wenjun, Hongliang Liu, Bensong Duan, Xinyuan Xu, Dennis Carmody, Sheng Luo, Kyle M. Walsh, et al. “Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer risk.” Cancer Sci 110, no. 6 (June 2019): 2022–32. https://doi.org/10.1111/cas.14017.Full Text Open Access Copy Link to Item
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Takahashi, Hannah, Alex J. Cornish, Amit Sud, Philip J. Law, Linden Disney-Hogg, Lisa Calvocoressi, Lingeng Lu, et al. “Mendelian randomization provides support for obesity as a risk factor for meningioma.” Sci Rep 9, no. 1 (January 22, 2019): 309. https://doi.org/10.1038/s41598-018-36186-6.Full Text Link to Item
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Nassiri, Farshad, Kenneth Aldape, Manmeet Alhuwalia, Priscilla Brastianos, Francois Ducray, Norbert Galldiks, Albert Kim, et al. “Highlights of the inaugural ten - the launch of Neuro-Oncology Advances.” Neurooncol Adv 1, no. 1 (2019): vdz016. https://doi.org/10.1093/noajnl/vdz016.Full Text Link to Item
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Shen, Erica, Margaret O. Johnson, Jessica W. Lee, Eric S. Lipp, Dina M. Randazzo, Annick Desjardins, Roger E. McLendon, et al. “Performance of a nomogram for IDH-wild-type glioblastoma patient survival in an elderly cohort.” Neurooncol Adv 1, no. 1 (2019): vdz036. https://doi.org/10.1093/noajnl/vdz036.Full Text Link to Item
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Semmes, Eleanor C., Chenan Zhang, and Kyle M. Walsh. “Intermediate phenotypes underlying osteosarcoma risk.” Oncotarget 9, no. 100 (December 21, 2018): 37345–46. https://doi.org/10.18632/oncotarget.26476.Full Text Link to Item
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Smith, Adam J. de, Kyle M. Walsh, Stephen S. Francis, Chenan Zhang, Helen M. Hansen, Ivan Smirnov, Libby Morimoto, et al. “BMI1 enhancer polymorphism underlies chromosome 10p12.31 association with childhood acute lymphoblastic leukemia.” Int J Cancer 143, no. 11 (December 1, 2018): 2647–58. https://doi.org/10.1002/ijc.31622.Full Text Link to Item
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Claus, Elizabeth B., Alex J. Cornish, Peter Broderick, Joellen M. Schildkraut, Sara E. Dobbins, Amy Holroyd, Lisa Calvocoressi, et al. “Genome-wide association analysis identifies a meningioma risk locus at 11p15.5.” Neuro Oncol 20, no. 11 (October 9, 2018): 1485–93. https://doi.org/10.1093/neuonc/noy077.Full Text Link to Item
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Zhang, Chenan, Joseph L. Wiemels, Helen M. Hansen, Julio Gonzalez-Maya, Alyson A. Endicott, Adam J. de Smith, Ivan V. Smirnov, et al. “Two HLA Class II Gene Variants Are Independently Associated with Pediatric Osteosarcoma Risk.” Cancer Epidemiol Biomarkers Prev 27, no. 10 (October 2018): 1151–58. https://doi.org/10.1158/1055-9965.EPI-18-0306.Full Text Link to Item
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Zhang, Chenan, Libby M. Morimoto, Adam J. de Smith, Helen M. Hansen, Julio Gonzalez-Maya, Alyson A. Endicott, Ivan V. Smirnov, et al. “Genetic determinants of childhood and adult height associated with osteosarcoma risk.” Cancer 124, no. 18 (September 15, 2018): 3742–52. https://doi.org/10.1002/cncr.31645.Full Text Open Access Copy Link to Item
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Mancini, Andrew, Ana Xavier-Magalhães, Wendy S. Woods, Kien-Thiet Nguyen, Alexandra M. Amen, Josie L. Hayes, Christof Fellmann, et al. “Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner.” Cancer Cell 34, no. 3 (September 10, 2018): 513-528.e8. https://doi.org/10.1016/j.ccell.2018.08.003.Full Text Link to Item
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Ojha, Juhi, Iryna Dyagil, Stuart C. Finch, Robert F. Reiss, Adam J. de Smith, Semira Gonseth, Mi Zhou, et al. “Genomic characterization of chronic lymphocytic leukemia (CLL) in radiation-exposed Chornobyl cleanup workers.” Environ Health 17, no. 1 (May 2, 2018): 43. https://doi.org/10.1186/s12940-018-0387-9.Full Text Link to Item
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Hayes, Josie, Yao Yu, Llewellyn E. Jalbert, Tali Mazor, Lindsey E. Jones, Matthew D. Wood, Kyle M. Walsh, et al. “Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas.” Neuro Oncol 20, no. 5 (April 9, 2018): 632–41. https://doi.org/10.1093/neuonc/nox205.Full Text Link to Item
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Wiemels, Joseph L., Kyle M. Walsh, Adam J. de Smith, Catherine Metayer, Semira Gonseth, Helen M. Hansen, Stephen S. Francis, et al. “GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21.” Nat Commun 9, no. 1 (January 18, 2018): 286. https://doi.org/10.1038/s41467-017-02596-9.Full Text Link to Item
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Wallace, Amelia D., Stephen S. Francis, Xiaorong Shao, Adam J. de Smith, Kyle M. Walsh, Roberta Mckean-Cowdin, Xiaomei Ma, et al. “A germ-line deletion of APOBEC3B does not contribute to subtype-specific childhood acute lymphoblastic leukemia etiology.” Haematologica 103, no. 1 (January 2018): e29–31. https://doi.org/10.3324/haematol.2017.179317.Full Text Link to Item
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Wallace, Amelia D., George A. Wendt, Lisa F. Barcellos, Adam J. de Smith, Kyle M. Walsh, Catherine Metayer, Joseph F. Costello, Joseph L. Wiemels, and Stephen S. Francis. “To ERV Is Human: A Phenotype-Wide Scan Linking Polymorphic Human Endogenous Retrovirus-K Insertions to Complex Phenotypes.” Front Genet 9 (2018): 298. https://doi.org/10.3389/fgene.2018.00298.Full Text Link to Item
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Zhang, Chenan, Adam J. de Smith, Ivan V. Smirnov, John K. Wiencke, Joseph L. Wiemels, John S. Witte, and Kyle M. Walsh. “Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma.” J Neurooncol 135, no. 2 (November 2017): 237–44. https://doi.org/10.1007/s11060-017-2569-7.Full Text Link to Item
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Bazyka, D., S. C. Finch, I. M. Ilienko, O. Lyaskivska, I. Dyagil, N. Trotsiuk, N. Gudzenko, et al. “Buccal mucosa micronuclei counts in relation to exposure to low dose-rate radiation from the Chornobyl nuclear accident and other medical and occupational radiation exposures.” Environ Health 16, no. 1 (June 23, 2017): 70. https://doi.org/10.1186/s12940-017-0273-x.Full Text Link to Item
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Endicott, Alyson A., Libby M. Morimoto, Cassie N. Kline, Joseph L. Wiemels, Catherine Metayer, and Kyle M. Walsh. “Perinatal factors associated with clinical presentation of osteosarcoma in children and adolescents.” Pediatr Blood Cancer 64, no. 6 (June 2017). https://doi.org/10.1002/pbc.26349.Full Text Link to Item
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Pekmezci, Melike, Terri Rice, Annette M. Molinaro, Kyle M. Walsh, Paul A. Decker, Helen Hansen, Hugues Sicotte, et al. “Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT.” Acta Neuropathol 133, no. 6 (June 2017): 1001–16. https://doi.org/10.1007/s00401-017-1690-1.Full Text Link to Item
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Telomeres Mendelian Randomization Collaboration, George, Philip C. Haycock, Stephen Burgess, Aayah Nounu, Jie Zheng, George N. Okoli, Jack Bowden, et al. “Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.” Jama Oncol 3, no. 5 (May 1, 2017): 636–51. https://doi.org/10.1001/jamaoncol.2016.5945.Full Text Link to Item
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Smith, Adam J. de, Maneet Kaur, Semira Gonseth, Alyson Endicott, Steve Selvin, Luoping Zhang, Ritu Roy, et al. “Correlates of Prenatal and Early-Life Tobacco Smoke Exposure and Frequency of Common Gene Deletions in Childhood Acute Lymphoblastic Leukemia.” Cancer Res 77, no. 7 (April 1, 2017): 1674–83. https://doi.org/10.1158/0008-5472.CAN-16-2571.Full Text Link to Item
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Francis, Stephen Starko, Amelia D. Wallace, George A. Wendt, Linlin Li, Fenyong Liu, Lee W. Riley, Scott Kogan, et al. “In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia.” Blood 129, no. 12 (March 23, 2017): 1680–84. https://doi.org/10.1182/blood-2016-07-723148.Full Text Link to Item
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Ohba, Shigeo, Joydeep Mukherjee, Tor-Christian Johannessen, Andrew Mancini, Tracy T. Chow, Matthew Wood, Lindsey Jones, et al. “Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process.” Cancer Res 76, no. 22 (November 15, 2016): 6680–89. https://doi.org/10.1158/0008-5472.CAN-16-0696.Full Text Link to Item
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Smith, Adam J. de, Juhi Ojha, Stephen S. Francis, Erica Sanders, Alyson A. Endicott, Helen M. Hansen, Ivan Smirnov, et al. “Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia.” Oncotarget 7, no. 45 (November 8, 2016): 72733–45. https://doi.org/10.18632/oncotarget.12238.Full Text Open Access Copy Link to Item
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Gonseth, Semira, Adam J. de Smith, Ritu Roy, Mi Zhou, Seung-Tae Lee, Xiaorong Shao, Juhi Ohja, et al. “Genetic contribution to variation in DNA methylation at maternal smoking-sensitive loci in exposed neonates.” Epigenetics 11, no. 9 (September 2016): 664–73. https://doi.org/10.1080/15592294.2016.1209614.Full Text Link to Item
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Ojha, Juhi, Veryan Codd, Christopher P. Nelson, Nilesh J. Samani, Ivan V. Smirnov, Nils R. Madsen, Helen M. Hansen, et al. “Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia.” Cancer Epidemiol Biomarkers Prev 25, no. 7 (July 2016): 1043–49. https://doi.org/10.1158/1055-9965.EPI-15-1329.Full Text Link to Item
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Walsh, Kyle M., Todd P. Whitehead, Adam J. de Smith, Ivan V. Smirnov, Minsun Park, Alyson A. Endicott, Stephen S. Francis, et al. “Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers.” Carcinogenesis 37, no. 6 (June 2016): 576–82. https://doi.org/10.1093/carcin/bgw037.Full Text Link to Item
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Wiemels, J. L., A. J. de Smith, J. Xiao, S. -. T. Lee, M. O. Muench, M. E. Fomin, M. Zhou, et al. “A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros.” Leukemia 30, no. 5 (May 2016): 1194–97. https://doi.org/10.1038/leu.2015.251.Full Text Link to Item
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Rice, Terri, Daniel H. Lachance, Annette M. Molinaro, Jeanette E. Eckel-Passow, Kyle M. Walsh, Jill Barnholtz-Sloan, Quinn T. Ostrom, et al. “Understanding inherited genetic risk of adult glioma - a review.” Neurooncol Pract 3, no. 1 (March 2016): 10–16. https://doi.org/10.1093/nop/npv026.Full Text Link to Item
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Endicott, Alyson A., Jennie W. Taylor, and Kyle M. Walsh. “Telomere length connects melanoma and glioma predispositions.” Aging (Albany Ny) 8, no. 3 (March 2016): 423–24. https://doi.org/10.18632/aging.100935.Full Text Link to Item
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David, Sean P., Ange Wang, Kristopher Kapphahn, Haley Hedlin, Manisha Desai, Michael Henderson, Lingyao Yang, et al. “Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans.” Ebiomedicine 4 (February 2016): 153–61. https://doi.org/10.1016/j.ebiom.2016.01.002.Full Text Open Access Copy Link to Item
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Walsh, Kyle M., Veryan Codd, Terri Rice, Christopher P. Nelson, Ivan V. Smirnov, Lucie S. McCoy, Helen M. Hansen, et al. “Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk.” Oncotarget 6, no. 40 (December 15, 2015): 42468–77. https://doi.org/10.18632/oncotarget.6468.Full Text Link to Item
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Walsh, Kyle M., Adam J. de Smith, Helen M. Hansen, Ivan V. Smirnov, Semira Gonseth, Alyson A. Endicott, Jianqiao Xiao, et al. “A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution.” Cancer Res 75, no. 22 (November 15, 2015): 4884–94. https://doi.org/10.1158/0008-5472.CAN-15-1105.Full Text Link to Item
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Walsh, Kyle M., John K. Wiencke, Daniel H. Lachance, Joseph L. Wiemels, Annette M. Molinaro, Jeanette E. Eckel-Passow, Robert B. Jenkins, and Margaret R. Wrensch. “Telomere maintenance and the etiology of adult glioma.” Neuro Oncol 17, no. 11 (November 2015): 1445–52. https://doi.org/10.1093/neuonc/nov082.Full Text Link to Item
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Eckel-Passow, Jeanette E., Daniel H. Lachance, Annette M. Molinaro, Kyle M. Walsh, Paul A. Decker, Hugues Sicotte, Melike Pekmezci, et al. “Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors.” N Engl J Med 372, no. 26 (June 25, 2015): 2499–2508. https://doi.org/10.1056/NEJMoa1407279.Full Text Link to Item
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Bell, Robert J. A., H Tomas Rube, Alex Kreig, Andrew Mancini, Shaun D. Fouse, Raman P. Nagarajan, Serah Choi, et al. “Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.” Science 348, no. 6238 (May 29, 2015): 1036–39. https://doi.org/10.1126/science.aab0015.Full Text Link to Item
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Reis, Gerald F., Melike Pekmezci, Helen M. Hansen, Terri Rice, Roxanne E. Marshall, Annette M. Molinaro, Joanna J. Phillips, et al. “CDKN2A loss is associated with shortened overall survival in lower-grade (World Health Organization Grades II-III) astrocytomas.” J Neuropathol Exp Neurol 74, no. 5 (May 2015): 442–52. https://doi.org/10.1097/NEN.0000000000000188.Full Text Link to Item
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Ostrom, Quinn T., Luc Bauchet, Faith G. Davis, Isabelle Deltour, James L. Fisher, Chelsea Eastman Langer, Melike Pekmezci, et al. “Response to "the epidemiology of glioma in adults: a 'state of the science' review".” Neuro Oncol 17, no. 4 (April 2015): 624–26. https://doi.org/10.1093/neuonc/nov022.Full Text Link to Item
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Hsu, Ling-I, Anand P. Chokkalingam, Farren B. S. Briggs, Kyle Walsh, Vonda Crouse, Cecilia Fu, Catherine Metayer, Joseph L. Wiemels, Lisa F. Barcellos, and Patricia A. Buffler. “Association of genetic variation in IKZF1, ARID5B, and CEBPE and surrogates for early-life infections with the risk of acute lymphoblastic leukemia in Hispanic children.” Cancer Causes Control 26, no. 4 (April 2015): 609–19. https://doi.org/10.1007/s10552-015-0550-3.Full Text Link to Item
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Hoover, Robert N., and Stephen J. Chanock. “Opportunities-and hard work-ahead.” J Natl Cancer Inst 107, no. 1 (January 2015): 398. https://doi.org/10.1093/jnci/dju398.Full Text Link to Item
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Osorio, Joseph A., Shawn L. Hervey-Jumper, Kyle M. Walsh, Jennifer L. Clarke, Nicholas A. Butowski, Michael D. Prados, and Mitchel S. Berger. “Familial gliomas: cases in two pairs of brothers.” J Neurooncol 121, no. 1 (January 2015): 135–40. https://doi.org/10.1007/s11060-014-1611-2.Full Text Link to Item
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Smith, Adam J. de, Kyle M. Walsh, Helen M. Hansen, Alyson A. Endicott, John K. Wiencke, Catherine Metayer, and Joseph L. Wiemels. “Somatic Mutation Allelic Ratio Test Using ddPCR (SMART-ddPCR): An Accurate Method for Assessment of Preferential Allelic Imbalance in Tumor DNA.” Plos One 10, no. 11 (2015): e0143343. https://doi.org/10.1371/journal.pone.0143343.Full Text Link to Item
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Bainbridge, Matthew N., Georgina N. Armstrong, M Monica Gramatges, Alison A. Bertuch, Shalini N. Jhangiani, Harsha Doddapaneni, Lora Lewis, et al. “Germline mutations in shelterin complex genes are associated with familial glioma.” J Natl Cancer Inst 107, no. 1 (January 2015): 384. https://doi.org/10.1093/jnci/dju384.Full Text Link to Item
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Claus, Elizabeth B., Kyle M. Walsh, John K. Wiencke, Annette M. Molinaro, Joseph L. Wiemels, Joellen M. Schildkraut, Melissa L. Bondy, Mitchel Berger, Robert Jenkins, and Margaret Wrensch. “Survival and low-grade glioma: the emergence of genetic information.” Neurosurg Focus 38, no. 1 (January 2015): E6. https://doi.org/10.3171/2014.10.FOCUS12367.Full Text Link to Item
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Ostrom, Quinn T., Luc Bauchet, Faith G. Davis, Isabelle Deltour, James L. Fisher, Chelsea Eastman Langer, Melike Pekmezci, et al. “The epidemiology of glioma in adults: a "state of the science" review.” Neuro Oncol 16, no. 7 (July 2014): 896–913. https://doi.org/10.1093/neuonc/nou087.Full Text Link to Item
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Walsh, Kyle M., Veryan Codd, Ivan V. Smirnov, Terri Rice, Paul A. Decker, Helen M. Hansen, Thomas Kollmeyer, et al. “Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.” Nat Genet 46, no. 7 (July 2014): 731–35. https://doi.org/10.1038/ng.3004.Full Text Link to Item
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Walsh, Kyle M., Adam J. de Smith, Tara C. Welch, Ivan Smirnov, Marc J. Cunningham, Xiaomei Ma, Anand P. Chokkalingam, et al. “Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell acute lymphoblastic leukemia.” Am J Hematol 89, no. 7 (July 2014): 721–25. https://doi.org/10.1002/ajh.23727.Full Text Link to Item
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Smith, Adam J. de, Kyle M. Walsh, Martha B. Ladner, Siming Zhang, Carmen Xiao, Franziska Cohen, Theodore B. Moore, et al. “The role of KIR genes and their cognate HLA class I ligands in childhood acute lymphoblastic leukemia.” Blood 123, no. 16 (April 17, 2014): 2497–2503. https://doi.org/10.1182/blood-2013-11-540625.Full Text Link to Item
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Walsh, K. M., A. P. Chokkalingam, L. -. I. Hsu, C. Metayer, A. J. de Smith, D. I. Jacobs, G. V. Dahl, et al. “Associations between genome-wide Native American ancestry, known risk alleles and B-cell ALL risk in Hispanic children.” Leukemia 27, no. 12 (December 2013): 2416–19. https://doi.org/10.1038/leu.2013.130.Full Text Link to Item
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Walsh, Kyle M., Adam J. de Smith, Anand P. Chokkalingam, Catherine Metayer, William Roberts, Lisa F. Barcellos, Joseph L. Wiemels, and Patricia A. Buffler. “GATA3 risk alleles are associated with ancestral components in Hispanic children with ALL.” Blood 122, no. 19 (November 7, 2013): 3385–87. https://doi.org/10.1182/blood-2013-08-524124.Full Text Link to Item
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Walsh, Kyle M., Terri Rice, Paul A. Decker, Matthew L. Kosel, Thomas Kollmeyer, Helen M. Hansen, Shichun Zheng, et al. “Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis.” Neuro Oncol 15, no. 8 (August 2013): 1041–47. https://doi.org/10.1093/neuonc/not051.Full Text Link to Item
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Walsh, Kyle M., Adam J. de Smith, Anand P. Chokkalingam, Catherine Metayer, Gary V. Dahl, Ling-i Hsu, Lisa F. Barcellos, Joseph L. Wiemels, and Patricia A. Buffler. “Novel childhood ALL susceptibility locus BMI1-PIP4K2A is specifically associated with the hyperdiploid subtype.” Blood 121, no. 23 (June 6, 2013): 4808–9. https://doi.org/10.1182/blood-2013-04-495390.Full Text Link to Item
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Rice, Terri, Shichun Zheng, Paul A. Decker, Kyle M. Walsh, Paige Bracci, Yuanyuan Xiao, Lucie S. McCoy, et al. “Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology.” Neuro Oncol 15, no. 5 (May 2013): 535–41. https://doi.org/10.1093/neuonc/nos324.Full Text Link to Item
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Walsh, Kyle M., Erik Anderson, Helen M. Hansen, Paul A. Decker, Matt L. Kosel, Thomas Kollmeyer, Terri Rice, et al. “Analysis of 60 reported glioma risk SNPs replicates published GWAS findings but fails to replicate associations from published candidate-gene studies.” Genet Epidemiol 37, no. 2 (February 2013): 222–28. https://doi.org/10.1002/gepi.21707.Full Text Link to Item
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Walsh, Kyle M., Ivan P. Gorlov, Helen M. Hansen, Xifeng Wu, Margaret R. Spitz, Huifeng Zhang, Emily Y. Lu, et al. “Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans.” Cancer Epidemiol Biomarkers Prev 22, no. 2 (February 2013): 251–60. https://doi.org/10.1158/1055-9965.EPI-12-1007-T.Full Text Link to Item
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Walsh, Kyle M., Christopher I. Amos, Angela S. Wenzlaff, Ivan P. Gorlov, Jennette D. Sison, Xifeng Wu, Margaret R. Spitz, et al. “Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans.” Oncotarget 3, no. 11 (November 2012): 1428–38. https://doi.org/10.18632/oncotarget.746.Full Text Link to Item
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DeWan, Andrew T., Kathryn Brigham Egan, Karen Hellenbrand, Keli Sorrentino, Nicole Pizzoferrato, Kyle M. Walsh, and Michael B. Bracken. “Whole-exome sequencing of a pedigree segregating asthma.” Bmc Med Genet 13 (October 9, 2012): 95. https://doi.org/10.1186/1471-2350-13-95.Full Text Link to Item
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Jenkins, Robert B., Yuanyuan Xiao, Hugues Sicotte, Paul A. Decker, Thomas M. Kollmeyer, Helen M. Hansen, Matthew L. Kosel, et al. “A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation.” Nat Genet 44, no. 10 (October 2012): 1122–25. https://doi.org/10.1038/ng.2388.Full Text Link to Item
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Kochar, Rabina, Kyle M. Walsh, Anil Jain, Steven J. Spalding, and Philip J. Hashkes. “Decreased use of non-steroidal anti-inflammatory drugs for the treatment of juvenile idiopathic arthritis in the era of modern aggressive treatment.” Rheumatol Int 32, no. 10 (October 2012): 3055–60. https://doi.org/10.1007/s00296-011-2084-7.Full Text Link to Item
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Bracci, Paige M., Jennette Sison, Helen Hansen, Kyle M. Walsh, Charles P. Quesenberry, Dan J. Raz, Margaret Wrensch, and John K. Wiencke. “Cigarette smoking associated with lung adenocarcinoma in situ in a large case-control study (SFBALCS).” J Thorac Oncol 7, no. 9 (September 2012): 1352–60. https://doi.org/10.1097/JTO.0b013e31825aba47.Full Text Link to Item
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Zhao, Linlu, Elizabeth W. Triche, Kyle M. Walsh, Michael B. Bracken, Audrey F. Saftlas, Josephine Hoh, and Andrew T. Dewan. “Genome-wide association study identifies a maternal copy-number deletion in PSG11 enriched among preeclampsia patients.” Bmc Pregnancy Childbirth 12 (June 29, 2012): 61. https://doi.org/10.1186/1471-2393-12-61.Full Text Link to Item
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Claus, Elizabeth B., Kyle M. Walsh, Lisa Calvocoressi, Melissa L. Bondy, Joellen M. Schildkraut, Margaret Wrensch, and Joseph L. Wiemels. “Cigarette smoking and risk of meningioma: the effect of gender.” Cancer Epidemiol Biomarkers Prev 21, no. 6 (June 2012): 943–50. https://doi.org/10.1158/1055-9965.EPI-11-1059.Full Text Link to Item
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Jacobs, Daniel I., Kyle M. Walsh, Margaret Wrensch, John Wiencke, Robert Jenkins, Richard S. Houlston, Melissa Bondy, et al. “Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: a novel candidate SNP approach.” Front Genet 3 (2012): 203. https://doi.org/10.3389/fgene.2012.00203.Full Text Link to Item
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Sebastiani, Paola, Nadia Solovieff, Andrew T. Dewan, Kyle M. Walsh, Annibale Puca, Stephen W. Hartley, Efthymia Melista, et al. “Genetic signatures of exceptional longevity in humans.” Plos One 7, no. 1 (2012): e29848. https://doi.org/10.1371/journal.pone.0029848.Full Text Link to Item
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Wu, Chengqing, Kyle M. Walsh, Andrew T. Dewan, Josephine Hoh, and Zuoheng Wang. “Disease risk prediction with rare and common variants.” Bmc Proc 5 Suppl 9, no. Suppl 9 (November 29, 2011): S61. https://doi.org/10.1186/1753-6561-5-S9-S61.Full Text Link to Item
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Walsh, Kyle M., and Michael B. Bracken. “Copy number variation in the dosage-sensitive 16p11.2 interval accounts for only a small proportion of autism incidence: a systematic review and meta-analysis.” Genet Med 13, no. 5 (May 2011): 377–84. https://doi.org/10.1097/GIM.0b013e3182076c0c.Full Text Link to Item
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Walsh, Kyle M., Murim Choi, Kjell Oberg, Matthew H. Kulke, James C. Yao, Chengqing Wu, Magdalena Jurkiewicz, et al. “A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum.” Endocr Relat Cancer 18, no. 1 (February 2011): 171–80. https://doi.org/10.1677/ERC-10-0248.Full Text Link to Item
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Murk, William, Kyle Walsh, Ling-I Hsu, Linlu Zhao, Michael B. Bracken, and Andrew T. Dewan. “Attempted replication of 50 reported asthma risk genes identifies a SNP in RAD50 as associated with childhood atopic asthma.” Hum Hered 71, no. 2 (2011): 97–105. https://doi.org/10.1159/000319536.Full Text Link to Item
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Walsh, Kyle M., Michael B. Bracken, William K. Murk, Josephine Hoh, and Andrew T. Dewan. “Association between reduced copy-number at T-cell receptor gamma (TCRgamma) and childhood allergic asthma: A possible role for somatic mosaicism.” Mutat Res 690, no. 1–2 (August 7, 2010): 89–94. https://doi.org/10.1016/j.mrfmmm.2010.05.005.Full Text Link to Item
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Clendenning, Mark, Mark E. Baze, Shuying Sun, Kyle Walsh, Sandya Liyanarachchi, Dan Fix, Victoria Schunemann, et al. “Origins and prevalence of the American Founder Mutation of MSH2.” Cancer Res 68, no. 7 (April 1, 2008): 2145–53. https://doi.org/10.1158/0008-5472.CAN-07-6599.Full Text Link to Item
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Book Sections
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Walsh, Kyle M. “Epidemiology of meningiomas.,” 169:3–15, 2020. https://doi.org/10.1016/B978-0-12-804280-9.00001-9.Full Text Link to Item
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Barnholtz-Sloan, Jill S., Quinn T. Ostrom, and David Cote. “Epidemiology of Brain Tumors.,” 36:395–419, 2018. https://doi.org/10.1016/j.ncl.2018.04.001.Full Text Link to Item
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Walsh, K. M., H. Ohgaki, and M. R. Wrensch. “Epidemiology.” In Gliomas, edited by M. S. Berger and M. Weller, 134:3–18. Elsevier, 2016.Link to Item
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Walsh, K. M., E. B. Claus, and M. R. Wrensch. “Epidemiology.” In Neuro-Oncology: The Essentials, edited by M. Berstein and M. S. Berger. Thieme, 2014.
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Walsh, K. M., M. S. Berger, and M. R. Wrensch. “Central Nervous System Tumors.” In Clinical Genomics: Practical Applications for Adult Patient Care, edited by M. F. Murray, M. W. Babyatsky, and M. A. Giovanni, 1:187–92. McGraw Hill Professional, 2013.
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Preprints
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Gibson, Rebecca A., Bijan Abar, Lily Elman, Kyle M. Walsh, Jillian H. Hurst, and Jennifer L. Cohen. “IDENTIFYING ASSOCIATIONS BETWEEN GENETIC CONDITIONS IN OFFSPRING AND PREGNANCY HEALTH COMPLICATIONS.” Cold Spring Harbor Laboratory, January 18, 2023. https://doi.org/10.1101/2023.01.17.23284690.Full Text
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Khaire, Archita, Courtney Wimberly, Eleanor Semmes, Jillian Hurst, and Kyle Walsh. “An integrated genome and phenome-wide association study approach to understanding Alzheimer’s disease predisposition.” MedRxiv, 2022. https://doi.org/10.1101/2022.01.03.22268705.Full Text
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Vyas, Neha, Courtney Wimberly, Makenzie Beaman, Samantha Kaplan, Line J. H. Rasmussen, Jasmin Wertz, Elizabeth Gifford, and Kyle Walsh. “Systematic Review and Meta-Analysis of the Effect of Adverse Childhood Experiences (ACEs) on Brain-Derived Neurotrophic Factor (BDNF) Levels.” MedRxiv, 2022. https://doi.org/10.1101/2022.08.16.22278345.Full Text
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- Teaching & Mentoring
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Recent Courses
- CRP 276: Statistical Methodology for Basic Research 2023
- CRP 276: Statistical Methodology for Basic Research 2022
- NEUROSCI 392: Neuroscience Independent Scholarship 2: Advanced Topics 2022
- CRP 276: Statistical Methodology for Basic Research 2021
- NEUROSCI 391: Neuroscience Independent Scholarship 1: Advanced Topics 2021
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