Maggie L DiNome
Professor of Surgery

I am a faculty member at Duke in the department of surgery, division of surgical oncology. I am a surgical breast oncologist whose clinical research interests focus on the de-escalation of axillary surgery for patients with lymph node positive breast cancer. My translational research interests focus on epigenetic modifications in breast cancer. I have returned to Duke (Medical School 1994), having spent the past 20 years in Los Angeles, most recently at UCLA where I served as Chief of Breast Surgery and Director of Breast Health for the UCLA Health System. I am honored to have joined the Duke faculty and am eager to grow the program in Wake County as the medical director of breast cancer services. 

Current Research Interests

My current clinical research interests focus on the de-escalation of lymph node surgery in breast cancer patients with lymph node positive disease. My research team and I have identified DNA methylation signatures that show high accuracy in differentiating patients with minimal nodal disease versus advanced nodal disease. We are developing a PCR-based assay for clinical use to support omission of axillary lymph node dissection for surgical staging of patients with minimal nodal disease. I am also interested in the epigenetic changes in triple negative breast cancer that influence treatment response to chemotherapy. We are also investigating the epigenetic differences among races and how these changes may impact risk for metastases, treatment response and overall survival.

Current Appointments & Affiliations

Contact Information

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