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Matthew L Becker

Hugo L. Blomquist Distinguished Professor of Chemistry
Chemistry
B120 Levine Science Res Center, 308 Research Drive, Durham, NC 27708
B120 Levine Science Res Center, 308 Research Drive, Durham, NC 27708

Overview


The Becker Laboratory for Functional Biomaterials is a multidisciplinary organic materials group working at the interface of chemistry, engineering and medicine.   We are developing families of degradable polymers with highly tunable physical and biological properties that are being applied to unmet needs in flexible electronics, soft tissue repair, neural, orthopedic and vascular tissue engineering.  We are also actively engaged in additive manufacturing and the development of custom inks that are enabling unique solutions to challenging design paradigms in biomaterials and drug delivery.

Current Appointments & Affiliations


Hugo L. Blomquist Distinguished Professor of Chemistry · 2020 - Present Chemistry, Trinity College of Arts & Sciences
Professor of Chemistry · 2019 - Present Chemistry, Trinity College of Arts & Sciences
Professor of Mechanical Engineering and Material Science · 2019 - Present Thomas Lord Department of Mechanical Engineering and Materials Science, Pratt School of Engineering
Professor of Biomedical Engineering · 2019 - Present Biomedical Engineering, Pratt School of Engineering

In the News


Published June 14, 2023
How the Partnership of a Duke Ph.D. and a Professor Led to Multiple Medical Device Start-Ups
Published January 26, 2022
Sweet Science: Researchers Develop Recyclable Plastics Based on Sugars
Published January 11, 2021
Post-Surgical Patch Releases Non-Opioid Painkiller Directly to the Wound

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Recent Publications


Observation of Dynamic Aggregation Behavior in Thermoresponsive Micro- and Nanoparticles via Diffusion-Ordered NMR Spectroscopy.

Journal Article J Am Chem Soc · March 19, 2025 Stimuli-responsive drug delivery systems have expanded the diversity of potential cargos by protecting payloads, extending circulation, and controlling payload release. However, quantitative characterization methods that accurately describe these complex s ... Full text Link to item Cite

Bioresorbable Suture Anchor Clips for Soft Tissue Wound Repair.

Journal Article Biomacromolecules · March 10, 2025 Mesh suture is an emerging technology for closing high-tension soft tissue wounds. However, bulky mesh surgical knots can irritate surrounding tissue and harbor bacteria, leading to an increased risk of infection and palpability. Thus, a degradable knotles ... Full text Link to item Cite

Synthesis of Cationic Cyclic Oligo(disulfide)s via Cyclo-Depolymerization: A Redox-Responsive and Potent Antibacterial Reagent.

Journal Article Journal of the American Chemical Society · February 2025 Antimicrobial peptides (AMPs) and synthetic topologically defined peptide mimics have been developed as alternatives to traditional small-molecule antibiotics. AMP mimetics arising from linear polymers used widely in preclinical studies have shown promise ... Full text Cite
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Recent Grants


Boston Children's/UCLA/Duke Next Generation Regeneration for Osteoarthritis (BUD NextGenRegen for OA)

ResearchInvestigator · Awarded by Advanced Research Projects Agency for Health · 2024 - 2029

University Training Program in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2027

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Education, Training & Certifications


Washington University in St. Louis · 2003 Ph.D.
Washington University in St. Louis · 2000 M.A.
Northwest Missouri State University · 1998 B.S.