Current Appointments & Affiliations
Adjunct Associate Professor in the Department of Psychiatry and Behavioral Sciences
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2022 - Present
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences,
Psychiatry & Behavioral Sciences
Recent Publications
APOE Genotype Influences on The Brain Metabolome of Aging Mice - Role for Mitochondrial Energetics in Mechanisms of Resilience in APOE2 Genotype.
Journal Article bioRxiv · March 1, 2025 Alzheimer's disease (AD) risk and progression are significantly influenced by APOE genotype with APOE4 increasing and APOE2 decreasing susceptibility compared to APOE3. While the effect of those genotypes was extensively studied on blood metabolome, less i ... Full text Link to item CiteIndividual bioenergetic capacity as a potential source of resilience to Alzheimer's disease.
Journal Article Nat Commun · February 24, 2025 Impaired glucose uptake in the brain is an early presymptomatic manifestation of Alzheimer's disease (AD), with symptom-free periods of varying duration that likely reflect individual differences in metabolic resilience. We propose a systemic "bioenergetic ... Full text Link to item CiteAcylcarnitines metabolism in depression: association with diagnostic status, depression severity and symptom profile in the NESDA cohort.
Journal Article Transl Psychiatry · February 23, 2025 Acylcarnitines (ACs) are involved in bioenergetics processes that may play a role in the pathophysiology of depression. Previous genomic evidence identified four ACs potentially linked to depression risk. We carried forward these ACs and tested the associa ... Full text Link to item CiteRecent Grants
The Role of Chemical Exposures in Alzheimer's Disease (AD) and its Trajectory
ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2029The UCSD Microbiome and Metagenomic Center
ResearchBiostatistician · Awarded by University of California - San Diego · 2022 - 2026Metabolomic Signatures for Disease Sub-classification and Target Prioritization in AMP-AD
ResearchInvestigator · Awarded by National Institutes of Health · 2018 - 2025View All Grants