Current Duke Appointments & Affiliations
Research Associate, Senior
Neurobiology,
Basic Science Departments
Recent Scholarly Works
Retinal degeneration in a mouse model of CRB1 disease rescued by the photoreceptor-specific CRB1-B isoform
Preprint · August 11, 2026 Abstract Many genes involved in inherited diseases produce alternate mRNA isoforms that remain poorly characterized. Functional assessment of these isoforms could therefore unlock new insi ... Full text CiteRejection of inappropriate synaptic partners in mouse retina mediated by transcellular FLRT2-UNC5 signaling.
Journal article Dev Cell · October 23, 2023 During nervous system development, neurons choose synaptic partners with remarkable specificity; however, the cell-cell recognition mechanisms governing rejection of inappropriate partners remain enigmatic. Here, we show that mouse retinal neurons avoid in ... Full text Link to item CiteCiliary Proteins Repurposed by the Synaptic Ribbon: Trafficking Myristoylated Proteins at Rod Photoreceptor Synapses.
Journal article International journal of molecular sciences · June 2022 The Unc119 protein mediates transport of myristoylated proteins to the photoreceptor outer segment, a specialized primary cilium. This transport activity is regulated by the GTPase Arl3 as well as by Arl13b and Rp2 that control Arl3 activation/inactivation ... Full text CiteRecent Grants
Molecular and cellular requirements for Crb1 gene function in the onset and therapeutic rescue of an inherited retinal degeneration
ResearchSenior Research Associate · Awarded by National Eye Institute · 2024 - 2028Precise assembly of retinal circuitry through rejection of inappropriate synaptic partners
ResearchPostdoctoral Associate · Awarded by National Eye Institute · 2021 - 2025View All Grants