Patty J Lee
Professor of Medicine

My overall research interests are in acute and chronic oxidant-induced lung injury and repair, specifically the distinct roles of stress-response pathways depending on the lung compartment or cell type(s) involved and their regulation by the immune system.  Using models of inhaled toxins, such as high oxygen concentrations, cigarette smoke, and microbes, we discovered previously unrecognized mechanistic roles for innate immune receptors, TLR4-NLRP3, mitochondrial health and cell fate, such as death and/or senescence.

Current Appointments & Affiliations

Contact Information

  • 5140 MSRB 3, 3 Genome Court, Durham, NC 27710
  • Box 103050, MSRB 3 Room 5140, Durham, NC 27710

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