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Scholarly Works - Preprints


Large-scale antibody reactome profiling identifies herpesvirus-autoantigen associations underlying chronic diseases.

Preprint · April 13, 2026 Herpesviruses infect nearly all humans and have long been implicated in autoimmune and chronic diseases, yet their immune interactions with host proteins have not been systematically characterized at population scale. We profiled immunoglobulin G reactivit ... Full text Link to item Cite

Network Analysis Reveals Protein Modules Associated with Childhood Respiratory Diseases.

Preprint · June 17, 2024 BACKGROUND: The first year of life is a period of rapid immune development that can impact health trajectories and the risk of developing respiratory-related diseases, such as asthma, recurrent infections, and eczema. However, the biology underlying subseq ... Full text Link to item Cite

Integrative epigenetics and transcriptomics identify aging genes in human blood

Preprint · 2024 Recent epigenome-wide studies have identified a large number of genomic regions that consistently exhibit changes in their methylation status with aging across diverse populations, but the functional consequences of these changes are largely unknown. On th ... Full text Cite

A meta-analysis of immune cell fractions at high resolution reveals novel associations with common phenotypes and health outcomes

Preprint · 2023 Abstract Background: Changes in cell-type composition of complex tissues are associated with a wide range of diseases, environmental risk factors and may be causally implicated in disease development and progression. However, these s ... Full text Cite