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Sean Ryan

Associate Professor of Orthopaedic Surgery
Orthopaedic Surgery
Office hours Available by email appointment request  

Overview


Dr. Sean Ryan is an Adult Reconstruction surgeon in the Division of Orthopaedic Surgery. He specializes in hip and knee primary and revision arthroplasty as well as periacetabular osteotomies for hip dysplasia. His research interests include patient outcomes, implant survivorship, implant design, periprosthetic joint infection, and instability.

Current Duke Appointments & Affiliations


Associate Professor of Orthopaedic Surgery · 2025 - Present Orthopaedic Surgery, Clinical Science Departments

Recent Scholarly Works


No increased risk of complications with dissolvable antibiotic beads in aseptic revision total hip arthroplasty.

Journal article J Clin Orthop Trauma · August 2026 BACKGROUND: Evidence supporting the use of dissolvable antibiotic beads in aseptic revision total hip arthroplasty (THA) is limited. The primary aim of this study was to evaluate whether dissolvable antibiotic bead use in aseptic revision THA reduces posto ... Full text Link to item Cite

Compatibility of Retrograde Intramedullary Nails With Knee Prostheses: A Comprehensive Analysis.

Journal article J Arthroplasty · July 2026 BACKGROUND: Periprosthetic distal femoral fractures pose major challenges in orthopaedic surgery, particularly among aging populations with total knee arthroplasties. Retrograde intramedullary nailing has emerged as a viable fixation option due to its biom ... Full text Link to item Cite

Impact of Obesity on Daily Activity Following Total Knee Arthroplasty.

Journal article J Arthroplasty · July 2026 BACKGROUND: Obesity is a major risk factor for knee osteoarthritis, frequently requiring total knee arthroplasty (TKA). Although TKA improves mobility and reduces pain, obesity's influence on postoperative activity and gait metrics remains unclear. This st ... Full text Link to item Cite
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Recent Grants


Persona® OsseoTi® Keel Compatibility Study

Clinical TrialPrincipal Investigator · Awarded by Zimmer Biomet Company · 2023 - 2036

Fresh Tissue Lab

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Total Joint Orthopedics, Inc. · 2026 - 2026

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Education


Ohio State University · 2015 M.D.