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Shanley Roach

Postdoctoral Associate
Integrative Immunobiology

Current Appointments & Affiliations


Recent Publications


Virus-induced perturbations in the mouse microbiome are impacted by microbial experience.

Journal Article mSphere · March 2025 The bacterial microbiome has a major impact on health and can shape metabolism, host tolerance, immune responses, and the outcome of future infections. The bacterial microbiome is highly variable between individuals. Specific pathogen-free animals have red ... Full text Cite

Experimental viral spillover across 25 million year gap in Rodentia reveals limited viral transmission and purifying selection of a picornavirus.

Journal Article mBio · October 2024 When a virus crosses from one host species to another, the consequences can be devastating. However, animal models to empirically evaluate cross-species transmission can fail to recapitulate natural transmission routes, physiologically relevant doses of pa ... Full text Cite

Tropism for ciliated cells is the dominant driver of influenza viral burst size in the human airway.

Journal Article Proceedings of the National Academy of Sciences of the United States of America · July 2024 Influenza viruses pose a significant burden on global human health. Influenza has a broad cellular tropism in the airway, but how infection of different epithelial cell types impacts replication kinetics and burden in the airways is not fully understood. U ... Full text Cite
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Recent Grants


Enterovirus Infection of Polarized Intestinal Cells

ResearchPostdoctoral Associate · Awarded by National Institute of Allergy and Infectious Diseases · 2021 - 2026

The Role of FcRn in Echovirus Entry and Pathogenesis

ResearchPostdoctoral Associate · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2026

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