https://orcid.org/0000-0002-4186-0846
Overview
I earned my B.A. in Biology and Psychology from The College of St. Benedict/St. John's University in 2017. I then graduated from the University of Minnesota in 2023 with a Ph.D. in Biochemistry and Molecular Biology after completing my thesis work in the laboratory of Dr. Ryan Langlois. My thesis broadly focused on host-pathogen interactions, with focuses on viral infections and innate immunity at barrier surfaces, virus-induced microbiome alterations, and virus transmission and evolution.
In the Coyne lab, my work centers around understanding the innate and adaptive immune responses to Enterovirus infections.
In the Coyne lab, my work centers around understanding the innate and adaptive immune responses to Enterovirus infections.
Current Duke Appointments & Affiliations
Postdoctoral Associate
Integrative Immunobiology,
Basic Science Departments
Recent Scholarly Works
Dirty mice better recapitulate key features of mRNA vaccine immunogenicity observed in humans.
Journal article mBio · August 2026 Although specific-pathogen-free (SPF) mice have traditionally been used to test candidate vaccines, recent work has demonstrated that "dirty" mice with broad microbial exposure more appropriately recapitulate human immune responses. Using a dirty mouse mod ... Full text CiteNaturally transmitted mouse viruses highlight the heterogeneity of virus transmission dynamics in the dirty mouse model.
Journal article Journal of virology · June 2025 Specific-pathogen-free (SPF) mice are widely used in biomedical research to model human infections. However, these animals do not always accurately recapitulate human immune responses. This is due, in part, to their lack of infection history. A growing num ... Full text CiteVirus-induced perturbations in the mouse microbiome are impacted by microbial experience.
Journal article mSphere · March 2025 The bacterial microbiome has a major impact on health and can shape metabolism, host tolerance, immune responses, and the outcome of future infections. The bacterial microbiome is highly variable between individuals. Specific pathogen-free animals have red ... Full text CiteRecent Grants
Enterovirus Infection of Polarized Intestinal Cells
ResearchPostdoctoral Associate · Awarded by National Institute of Allergy and Infectious Diseases · 2021 - 2026The Role of FcRn in Echovirus Entry and Pathogenesis
ResearchPostdoctoral Associate · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2026View All Grants