Scholars@Duke
Sharon Gerecht

Sharon Gerecht

Paul M. Gross Distinguished Professor
Biomedical Engineering

Scholarly Works - Preprints

Artery-on-chip demonstrates smooth muscle function comparable to both healthy and diseased living tissues

Preprint · 2025 ABSTRACT Arterial diseases affect the mechanical properties of blood vessels, which then alter their function via complex mechanisms. To develop and test effective treatments, microphysiological systems replicating the function and mechanics of a ... Full text Cite

Engineering the microstructure and spatial bioactivity of MAP scaffolds in vitro instructs neovascularization in vivo

Preprint · 2023 In tissues where the vasculature is either lacking or abnormal, biomaterials can be designed to promote vessel formation and enhance tissue repair. In this work, we independently tune the microstructure and bioactivity of microporous annealed particle (MAP ... Full text Cite

Scalable Production of Human Erythrocytes from Induced Pluripotent Stem Cells

Preprint · 2016 ABSTRACT In vitro production of erythrocytes in physiologic numbers from human induced pluripotent stem cells (hiPSCs) holds great promise for improved transfusion medicine and novel cell therapies. We report here, for the first time, a strategy ... Full text Cite