Current Appointments & Affiliations
Associate Professor of Pathology
·
2024 - Present
Pathology,
Clinical Science Departments
Associate Professor in Neurology
·
2024 - Present
Neurology, Behavioral Neurology,
Neurology
Faculty Network Member of the Duke Institute for Brain Sciences
·
2022 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Recent Publications
Synchronous diagnosis of multicentric glioma with distinct isocitrate dehydrogenase molecular profiles: a case report.
Journal Article CNS Oncol · December 2026 This case report characterizes the molecular pathology of two synchronous IDH mutant gliomas in a 28-year-old female patient. The patient exhibited symptoms of dizziness, retro-orbital pain, headache, and numbness with paresthesia in her right arm. MRI ima ... Full text Link to item CiteMolecular signatures and biomarker development for limbic-predominant age-related TDP-43 encephalopathy (LATE).
Journal Article Acta Neuropathol · May 15, 2026 Limbic-predominant age-related TDP-43 encephalopathy (LATE) is a neurodegenerative disease marked by TDP-43 proteinopathy, affecting approximately one-third of individuals aged 80 and above. LATE neuropathological change (LATE-NC) is characterized by the a ... Full text Link to item CiteThe prevalence of Lewy body pathology across nine international community-based cohorts
Journal Article Brain · March 26, 2026 AbstractReported prevalence estimates of Lewy body pathology (LBP) vary widely, often without considering brain regional distributions or demographic influences. Large, population-representative autopsy c ... Full text CiteRecent Grants
Elucidating the role of vascular dysfunction in LATE, LATE-AD, and FTLD-TDP
ResearchPrincipal Investigator · Awarded by Alzheimer's Association · 2024 - 2027Characterizing Spatial Variations in RNA Isoform Expression with Alzheimer's Disease
ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2026Elucidating the molecular basis of normal and resilient human brain aging
ResearchPrincipal Investigator · Awarded by University of California - San Francisco · 2024 - 2026View All Grants
Education
Johns Hopkins University ·
2012
Ph.D.
National Taiwan University (Taiwan) ·
2003
M.D.