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Shih-Hsiu Wang

Associate Professor of Pathology
Pathology
Box 3712, Durham, NC 27710
40 Duke Medicine Circle, Box 3712, Durham, NC 27710

Current Appointments & Affiliations


Associate Professor of Pathology · 2024 - Present Pathology, Clinical Science Departments
Associate Professor in Neurology · 2024 - Present Neurology, Behavioral Neurology, Neurology
Faculty Network Member of the Duke Institute for Brain Sciences · 2022 - Present Duke Institute for Brain Sciences, University Institutes and Centers

Recent Publications


Star-shaped TDP-43 inclusions in the oldest-old.

Journal Article J Neuropathol Exp Neurol · April 1, 2025 Full text Link to item Cite

Performance of Polygenic Risk Scores for Primary Open-Angle Glaucoma in Populations of African Descent.

Journal Article JAMA Ophthalmol · January 1, 2025 IMPORTANCE: Primary open-angle glaucoma (POAG) polygenic risk scores (PRSs) continue to be evaluated in primarily European-ancestry populations despite higher prevalence and worse outcomes in African-ancestry populations. OBJECTIVE: To evaluate how establi ... Full text Link to item Cite

Very-late-onset multiple Acyl-coenzyme a dehydrogenase deficiency with elevated GDF-15 and Aldolase: a case report.

Journal Article Neuromuscul Disord · December 2024 A 72-year-old woman on sertraline and levothyroxine (Levoxyl) presented to clinic with progressive proximal > distal and left > right upper and lower extremity weakness. She had length-dependent paresthesias and sensory deficits. Aldolase was elevated but ... Full text Link to item Cite
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Recent Grants


Elucidating the role of vascular dysfunction in LATE, LATE-AD, and FTLD-TDP

ResearchPrincipal Investigator · Awarded by Alzheimer's Association · 2024 - 2027

Characterizing Spatial Variations in RNA Isoform Expression with Alzheimer's Disease

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2026

Elucidating the molecular basis of normal and resilient human brain aging

ResearchPrincipal Investigator · Awarded by University of California - San Francisco · 2024 - 2026

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Education, Training & Certifications


Johns Hopkins University · 2012 Ph.D.
National Taiwan University (Taiwan) · 2003 M.D.