Scholars@Duke
Shuang Li

Shuang Li

Biostatistician, Senior
Duke Clinical Research Institute
shuang.li@duke.edu
DUMC#: 3850, Office 4512, Durham, NC 27701
300 W Morgan St, Durham Centre, Durham, NC 27705

Scholarly Works

Impact of In-Hospital STEMI on Reperfusion Times and Clinical Outcomes.

Journal article Circ Cardiovasc Interv · February 2026 BACKGROUND: ST-segment-elevation myocardial infarction (STEMI) is uncommon among inpatients already admitted to the hospital for other indications. Prior studies reported significant differences in clinical characteristics and outcomes of patients who deve ... Full text Link to item Cite

Influence of ejection fraction on outcomes with sacubitril/valsartan in patients with worsening heart failure with EF>40%: The PARAGLIDE-HF Trial.

Conference American heart journal · November 2025 BackgroundIn the PARAGLIDE-HF trial, treatment with sacubitril/valsartan (Sac/Val) was associated with greater reduction in NT-proBNP than valsartan (Val) alone in patients stabilized after an episode of worsening heart failure (HF) with left vent ... Full text Cite

Daylight Savings Time and Acute Myocardial Infarction.

Journal article JAMA Netw Open · September 2, 2025 IMPORTANCE: Previous data suggest that the time changes associated with daylight savings time (DST) may be associated with an increased incidence of acute myocardial infarction (AMI). OBJECTIVE: To determine whether the incidence of patients presenting wit ... Full text Link to item Cite

Prediction of 1-Year Major Adverse Cardiovascular Events in Chronic Limb Threatening Ischemia.

Journal article JACC Adv · August 2025 BACKGROUND: Patients with chronic limb threatening ischemia (CLTI) are at risk for major adverse cardiovascular events (MACE), yet few tools exist for risk stratification. OBJECTIVES: The purpose of this study was to derive and validate a CLTI MACE risk pr ... Full text Link to item Cite

Inpatient Outcomes for Patients With Peripheral Artery Disease Hospitalized for Acute Myocardial Infarction.

Journal article J Am Heart Assoc · June 17, 2025 BACKGROUND: Patients with both peripheral artery disease (PAD) and coronary artery disease are at heightened risk for adverse cardiovascular outcomes. Although long-term risk has been well documented, contemporary in-hospital outcomes for patients with PAD ... Full text Link to item Cite

Characteristics of High-Performing Hospitals in Cardiogenic Shock Following Acute Myocardial Infarction.

Journal article Am J Cardiol · June 15, 2024 Cardiogenic shock after acute myocardial infarction (AMI-CS) carries significant mortality despite advances in revascularization and mechanical circulatory support. We sought to identify the process-based and structural characteristics of centers with lowe ... Full text Link to item Cite

Impact of baseline kidney dysfunction on oral diuretic efficacy following hospitalization for heart failure - insights from TRANSFORM-HF.

Journal article Eur J Heart Fail · May 2024 AIM: Among patients discharged after hospitalization for heart failure (HF), a strategy of torsemide versus furosemide showed no difference in all-cause mortality or hospitalization. Clinicians have traditionally favoured torsemide in the setting of kidney ... Full text Link to item Cite

Ventricular Arrhythmias After Primary Percutaneous Coronary Intervention for STEMI.

Journal article JAMA Netw Open · May 1, 2024 IMPORTANCE: Currently, mortality risk for patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) with an uncomplicated postprocedure course is low. Less is known regarding the risk of ... Full text Link to item Cite

Implementation of High-Sensitivity Cardiac Troponin Assays in the United States.

Journal article J Am Coll Cardiol · January 24, 2023 BACKGROUND: Few data exist regarding the implementation of high-sensitivity cardiac troponin (hs-cTn) assays in the United States since their approval. OBJECTIVES: This study sought to explore trends in hs-cTn assay implementation over time and assess the ... Full text Link to item Cite

Characteristics, Process Metrics, and Outcomes Among Patients With ST-Elevation Myocardial Infarction in Rural vs Urban Areas in the US: A Report From the US National Cardiovascular Data Registry.

Journal article JAMA Cardiol · October 1, 2022 IMPORTANCE: Patients with ST-segment elevation myocardial infarction (STEMI) living in rural settings often have worse clinical outcomes compared with their urban counterparts. Whether this discrepancy is due to clinical characteristics or delays in timely ... Full text Link to item Cite

Effect of Mailing Educational Material to Patients With Atrial Fibrillation and Their Clinicians on Use of Oral Anticoagulants: A Randomized Clinical Trial.

Journal article JAMA Netw Open · May 2, 2022 IMPORTANCE: Only about half of patients with atrial fibrillation (AF) who are at increased risk for stroke are treated with an oral anticoagulant (OAC), despite guideline recommendations for their use. Educating patients with AF about prevention of stroke ... Full text Link to item Cite

Sex Differences in Management and Outcomes of Acute Myocardial Infarction Patients Presenting With Cardiogenic Shock.

Journal article JACC Cardiovasc Interv · March 28, 2022 OBJECTIVES: The aim of this study was to examine the sex differences in the risk profile, management, and outcomes among patients presenting with acute myocardial infarction cardiogenic shock (AMI-CS). BACKGROUND: Contemporary clinical data regarding sex d ... Full text Link to item Cite

Racial Disparities in Invasive Management for Patients With Acute Myocardial Infarction With Chronic Kidney Disease.

Journal article Circ Cardiovasc Interv · January 2022 BACKGROUND: Due to increased risks of contrast nephropathy, chronic kidney disease (CKD) can deter consideration of invasive management for patients with myocardial infarction (MI). Black patients have a higher prevalence of CKD. Whether racial disparities ... Full text Link to item Cite

Ten-Year Trends in Patient Characteristics, Treatments, and Outcomes in Myocardial Infarction From National Cardiovascular Data Registry Chest Pain-MI Registry.

Journal article Circulation. Cardiovascular quality and outcomes · January 2022 BackgroundThe Chest Pain-MI registry affords a 10-year perspective of the acute myocardial infarction (MI) patient characteristics, management, and clinical outcomes in the United States. We report the changes in the treatment and cardiovascular o ... Full text Cite

The Impact of American College of Cardiology Chest Pain Center Accreditation on Guideline Recommended Acute Myocardial Infarction Management.

Journal article Crit Pathw Cardiol · December 1, 2021 BACKGROUND: Whether American College of Cardiology (ACC) Chest Pain Center (CPC) accreditation alters guidelines adherence rates is unclear. METHODS: We analyzed patient-level, hospital-reported, quality metrics for myocardial infarction (MI) patients from ... Full text Link to item Cite

Atrial Fibrillation and Coronary Artery Disease: A Long-Term Perspective on the Need for Combined Antithrombotic Therapy.

Journal article Circ Cardiovasc Interv · December 2021 BACKGROUND: Older adults with atrial fibrillation (AF) are often treated with the shortest possible duration of antiplatelet/anticoagulant therapy after myocardial infarction (MI) or percutaneous coronary intervention (PCI) due to concern for bleeding. How ... Full text Link to item Cite

Patient perceptions and use of non-statin lipid lowering therapy among patients with or at risk for atherosclerotic cardiovascular disease: Insights from the PALM registry.

Journal article Clinical cardiology · June 2021 BackgroundNon-statin lipid lowering therapies (LLTs) provide additional treatment options for patients. Use patterns and patient perceptions of non-statin LLT remain incompletely described.HypothesisThe guideline-recommended statin intens ... Full text Cite

Implantable Cardioverter Defibrillator Utilization and Mortality Among Patients ≥65 Years of Age With a Low Ejection Fraction After Coronary Revascularization.

Journal article Am J Cardiol · January 1, 2021 The purpose of this analysis was to assess implantable cardioverter-defibrillator (ICD) utilization and its association with mortality among patients ≥65 years of age after coronary revascularization. Patients in the National Cardiovascular Database Regist ... Full text Link to item Cite

Patient-Perceived Versus Actual Risk of Cardiovascular Disease and Associated Willingness to Consider and Use Prevention Therapy.

Journal article Circulation. Cardiovascular quality and outcomes · January 2021 BackgroundCardiovascular prevention guidelines use estimated 10-year atherosclerotic cardiovascular disease (CVD) risk based on the pooled cohort equations to guide treatment decisions and engage patients in shared decision-making. We sought to de ... Full text Cite

Insulin Use and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Graft Surgery.

Journal article Braz J Cardiovasc Surg · October 1, 2020 OBJECTIVE: To describe insulin use and postoperative glucose control in patients undergoing coronary artery bypass graft (CABG) surgery. METHODS: We examined 2,390 patients with and without diabetes enrolled in the Contemporary Analysis of Perioperative Ca ... Full text Link to item Cite

Beliefs, risk perceptions, and lipid management among patients with and without diabetes: Results from the PALM registry.

Journal article American heart journal · July 2020 Intensive lipid management is critical to reduce cardiovascular (CV) risk for patients with diabetes mellitus (DM).MethodsWe performed an observational study of 7628 patients with (n = 2943) and without DM (n = 4685), enrolled in the Provider Asse ... Full text Cite

Intensity of Lipid Lowering With Statin Therapy in Patients With Cerebrovascular Disease Versus Coronary Artery Disease: Insights from the PALM Registry.

Journal article J Am Heart Assoc · October 2019 Background Current treatment guidelines strongly recommend statin therapy for secondary prevention. However, it remains unclear whether patients' perceptions of cardiovascular risk, beliefs on cholesterol, or the intensity of prescribed statin therapy diff ... Full text Open Access Link to item Cite

Practice-level variation in statin use and low-density lipoprotein cholesterol control in the United States: Results from the Patient and Provider Assessment of Lipid Management (PALM) registry.

Journal article Am Heart J · August 2019 BACKGROUND: Adherence to guideline-recommended statin recommendations in the United States is suboptimal. Patients' likelihood to be treated according to guidelines may vary by the practice in which they are treated. METHODS: Variation in the use of statin ... Full text Link to item Cite

Association of Clinician Knowledge and Statin Beliefs With Statin Therapy Use and Lipid Levels (A Survey of US Practice in the PALM Registry).

Journal article The American journal of cardiology · April 2019 Guideline implementation requires clinician knowledge but may be influenced by pre-existing beliefs and biases. We assessed the association of these clinician factors with lipid management following the release of the 2013 American College of Cardiology/Am ... Full text Cite

Patient-Reported Reasons for Declining or Discontinuing Statin Therapy: Insights From the PALM Registry.

Journal article Journal of the American Heart Association · April 2019 Background Many adults eligible for statin therapy for cardiovascular disease prevention are untreated. Our objective was to investigate patient-reported reasons for statin underutilization, including noninitiation, refusal, and discontinuation. Methods an ... Full text Cite

Measurement of Low-Density Lipoprotein Cholesterol Levels in Primary and Secondary Prevention Patients: Insights From the PALM Registry.

Journal article J Am Heart Assoc · September 18, 2018 Background The 2013 American College of Cardiology/American Heart Association Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults recommended testing low-density lipoprotein cholesterol ( LDL -C) to ident ... Full text Link to item Cite

The impact of clinical vs administrative claims coding on hospital risk-adjusted outcomes.

Journal article Clin Cardiol · September 2018 BACKGROUND: Comorbid condition and hospital risk-adjusted outcomes prevalence were compared based on clinical registry vs administrative claims data. HYPOTHESIS: Risk-adjusted outcomes will vary depending on the source of comorbidity data used. METHODS: Cl ... Full text Link to item Cite

Does clinician-reported lipid guideline adoption translate to guideline-adherent care? An evaluation of the Patient and Provider Assessment of Lipid Management (PALM) registry.

Journal article Am Heart J · June 2018 BACKGROUND: The 2013 American College of Cardiology (ACC)/American Heart Association (AHA) cholesterol guideline recommends statin treatment based on patients' predicted atherosclerotic cardiovascular disease (ASCVD) risk. Whether clinician-reported guidel ... Full text Link to item Cite

Neighborhood Socioeconomic Disadvantage and Care After Myocardial Infarction in the National Cardiovascular Data Registry.

Journal article Circ Cardiovasc Qual Outcomes · June 2018 BACKGROUND: Patients living in disadvantaged neighborhoods are at high risk for adverse outcomes after acute myocardial infarction (MI). Whether residential socioeconomic status (SES) is associated with quality of in-hospital care among patients presenting ... Full text Link to item Cite

An Observational Study of the Association of Video- Versus Text-Based Informed Consent With Multicenter Trial Enrollment: Lessons From the PALM Study (Patient and Provider Assessment of Lipid Management).

Journal article Circ Cardiovasc Qual Outcomes · April 2018 BACKGROUND: Patient participation in clinical research is low, in part because of the length and complexity of the informed consent process. Video informed consent may enhance the appeal of research and help break down barriers to participation. METHODS AN ... Full text Link to item Cite

Clopidogrel reloading for patients with acute myocardial infarction already on clopidogrel therapy.

Journal article Eur Heart J · January 14, 2018 AIMS: We sought to determine the association of clopidogrel reloading with in-hospital bleeding and mortality in contemporary practice. METHODS AND RESULTS: We examined clopidogrel reloading for ST-segment elevation myocardial infarction (STEMI) and non-ST ... Full text Link to item Cite

Association of acute kidney injury and chronic kidney disease with processes of care and long-term outcomes in patients with acute myocardial infarction.

Journal article Eur Heart J Qual Care Clin Outcomes · January 1, 2018 AIMS: To examine the association of acute kidney injury (AKI) with long-term outcomes after myocardial infarction (MI), and evaluate whether effect modification is present according to baseline chronic kidney disease (CKD) status. METHODS AND RESULTS: ACTI ... Full text Link to item Cite

Glycemic control in patients undergoing coronary artery bypass graft surgery: Clinical features, predictors, and outcomes.

Journal article J Crit Care · December 2017 PURPOSE: Critically ill patients with hyperglycemia have worse prognosis. The degree to which glycemic control is achieved following CABG surgery and the association with clinical outcomes is not well understood. MATERIALS AND METHODS: We studied patients ... Full text Link to item Cite

Lipid management in contemporary community practice: Results from the Provider Assessment of Lipid Management (PALM) Registry.

Journal article American heart journal · November 2017 BackgroundThe latest cholesterol guidelines have shifted focus from achieving low-density lipoprotein cholesterol (LDL-C) targets toward statin use and intensity guided by atherosclerotic cardiovascular disease (ASCVD) risk.MethodsStatin ... Full text Cite

Precatheterization Use of P2Y12 Inhibitors in Non-ST-Elevation Myocardial Infarction Patients Undergoing Early Cardiac Catheterization and In-Hospital Coronary Artery Bypass Grafting: Insights From the National Cardiovascular Data Registry®.

Journal article J Am Heart Assoc · September 22, 2017 BACKGROUND: Current guidelines recommend early P2Y12 inhibitor administration in non-ST-elevation myocardial infarction, but it is unclear if precatheterization use is associated with longer delays to coronary artery bypass grafting (CABG) or higher risk o ... Full text Link to item Cite

Selection of Stent Type in Patients With Atrial Fibrillation Presenting With Acute Myocardial Infarction: An Analysis From the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry-Get With the Guidelines.

Journal article J Am Heart Assoc · August 21, 2017 BACKGROUND: Patients receiving oral anticoagulation in addition to dual-antiplatelet therapy are known to be at high risk for bleeding events; thus, the selection of a drug-eluting stent (DES) versus a bare metal stent (BMS) can have important implications ... Full text Link to item Cite

Race and Sex Differences in Management and Outcomes of Patients After ST-Elevation and Non-ST-Elevation Myocardial Infarct: Results From the NCDR.

Journal article Clin Cardiol · October 2016 BACKGROUND: Race and sex have been shown to affect management of myocardial infarction (MI); however, it is unclear if such disparities exist in contemporary care of ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial ... Full text Link to item Cite

The association of left ventricular ejection fraction with clinical outcomes after myocardial infarction: Findings from the Acute Coronary Treatment and Intervention Outcomes Network (ACTION) Registry-Get With the Guidelines (GWTG) Medicare-linked database.

Journal article Am Heart J · August 2016 BACKGROUND: Little is known about the relationship between ejection fraction (EF) and clinical outcomes among older patients with myocardial infarction in contemporary clinical practice. METHODS: Data on 82,558 patients 65 years or older with ST-elevation ... Full text Link to item Cite

Comparison of performance on Hospital Compare process measures and patient outcomes between hospitals that do and do not participate in Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines.

Journal article Am Heart J · May 2016 BACKGROUND: Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines (ACTION Registry-GWTG) was designed to measure and improve the treatment and outcomes of patients with acute myocardial infarction (AMI), yet it is unkn ... Full text Link to item Cite

The Association of Transfer Rate From Hospitals Without Revascularization Capabilities and Mortality Risk for Older Non-ST-Segment Elevation Myocardial Infarction Patients.

Journal article Clin Cardiol · December 2015 BACKGROUND: Interhospital transfer invasive management patterns and implications for older non-ST-segment elevation myocardial infarction (NSTEMI) patients initially presenting to non-revascularization-capable hospitals have not been explored. HYPOTHESIS: ... Full text Link to item Cite

Risk factor burden and control at the time of admission in patients with acute myocardial infarction: Results from the NCDR.

Journal article Am Heart J · July 2015 BACKGROUND: Understanding risk factor burden and control as well as perceived risk prior to acute myocardial infarction (MI) presentation may identify gaps in contemporary systems of care. METHODS: Patients presenting with MI in the National Cardiovascular ... Full text Link to item Cite

Nationwide Analysis of Patients With ST-Segment-Elevation Myocardial Infarction Transferred for Primary Percutaneous Intervention: Findings From the American Heart Association Mission: Lifeline Program.

Journal article Circ Cardiovasc Interv · May 2015 BACKGROUND: Current American College of Cardiology/American Heart Association guidelines recommend transfer and primary percutaneous coronary intervention (PCI) for ST-segment-elevation myocardial infarction (STEMI) patients within the time limit of first ... Full text Link to item Cite

Targeted versus standard feedback: results from a randomized quality improvement trial.

Journal article Am Heart J · January 2015 BACKGROUND: Quality improvement is central to improving the care of patients with cardiovascular disease; however, the optimum type of data feedback to support such efforts is unknown. METHODS: Over 26 months, 149 eligible Acute Coronary Treatment and Inte ... Full text Link to item Cite

Frequency of nonsystem delays in ST-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention and implications for door-to-balloon time reporting (from the American Heart Association Mission: Lifeline program).

Journal article Am J Cardiol · July 1, 2014 The percentage of patients with primary percutaneous coronary intervention (PCI) with door-to-balloon (D2B) times ≤90 minutes is used as a hospital performance measure for public reporting. Patients can be excluded from reporting for nonsystem-related dela ... Full text Link to item Cite

The quality of antiplatelet and anticoagulant medication administration among ST-segment elevation myocardial infarction patients transferred for primary percutaneous coronary intervention.

Journal article Am Heart J · June 2014 BACKGROUND: Timely and appropriate use of antiplatelet and anticoagulant therapies has been shown to improve outcomes among ST-segment elevation myocardial infarction (STEMI) patients but has not been well described in patients transferred for primary perc ... Full text Link to item Cite

Characteristics, management, and outcomes of cocaine-positive patients with acute coronary syndrome (from the National Cardiovascular Data Registry).

Journal article Am J Cardiol · March 1, 2014 Although cocaine ingestion may cause or contribute to myocardial infarction (MI), few contemporary data are available describing cocaine-associated MI. We describe the characteristics, management, and outcomes of patients with MI and recent cocaine use fro ... Full text Link to item Cite

Hospital patterns of medical management strategy use for patients with non-ST-elevation myocardial infarction and 3-vessel or left main coronary artery disease.

Journal article Am Heart J · March 2014 BACKGROUND: Patients with non-ST-elevation myocardial infarction (NSTEMI) and three-vessel or left main coronary disease (3VD/LMD) have a high risk of long-term mortality when treated with a medical management strategy (MMS) compared with revascularization ... Full text Link to item Cite

Reperfusion times and in-hospital outcomes among patients with an isolated posterior myocardial infarction: insights from the National Cardiovascular Data Registry (NCDR).

Journal article Am Heart J · March 2014 BACKGROUND: A posterior myocardial infarction (PMI) is associated with significant morbidity and delays in recognition may prevent the timely revascularization of these patients. The present study sought to evaluate the reperfusion times and in-hospital ou ... Full text Link to item Cite

Outcome characteristics of multiple-valve surgery: comparison with single-valve procedures.

Journal article Innovations (Philadelphia, Pa.) · January 2014 ObjectiveMultiple-valve (MUV) procedures currently exhibit higher operative mortality than do single-valve procedures, but a paucity of scientific information exists to explain the observation. This topic was examined using The Society of Thoracic ... Full text Cite

The association between smoking and long-term outcomes after non-ST-segment elevation myocardial infarction in older patients.

Journal article Am Heart J · December 2013 BACKGROUND: Prior studies have observed that smokers have paradoxically favorable 1-year mortality rates after acute coronary syndromes, but it is unknown whether this association extends to long-term outcomes and to older patients. METHODS: We identified ... Full text Link to item Cite

Warfarin use among older atrial fibrillation patients with non-ST-segment elevation myocardial infarction managed with coronary stenting and dual antiplatelet therapy.

Journal article Am Heart J · November 2013 BACKGROUND: We sought to determine the risk of readmission for bleeding and major cardiac events in stented non-ST-segment elevation myocardial infarction (NSTEMI) atrial fibrillation (AF) patients. METHODS: For this patient population, selection of an ant ... Full text Link to item Cite

Association between natriuretic peptides and mortality among patients admitted with myocardial infarction: a report from the ACTION Registry(R)-GWTG™.

Journal article Clin Chem · August 2013 BACKGROUND: Patients with increased blood concentrations of natriuretic peptides (NPs) have poor cardiovascular outcomes after myocardial infarction (MI). The objectives of this analysis were to evaluate the utilization and the prognostic value of NP in a ... Full text Link to item Cite

Long-term outcomes after invasive management for older patients with non-ST-segment elevation myocardial infarction.

Journal article Circ Cardiovasc Qual Outcomes · May 1, 2013 BACKGROUND: Early invasive management is recommended for patients with non-ST-segment elevation myocardial infarction (MI), but the incidence of long-term outcomes after early catheterization among older patients and the relationship of revascularization p ... Full text Link to item Cite

Relation between time of symptom onset of ST-segment elevation myocardial infarction and patient baseline characteristics: from the National Cardiovascular Data Registry.

Journal article Clin Cardiol · April 2013 BACKGROUND: The presence of a morning excess of ST-segment elevation myocardial infarction (STEMI) has been observed. The relation between patient characteristics and timing of STEMI may provide insight into the biological processes responsible for this ph ... Full text Link to item Cite

Polyvascular disease and long-term cardiovascular outcomes in older patients with non-ST-segment-elevation myocardial infarction.

Journal article Circ Cardiovasc Qual Outcomes · July 1, 2012 BACKGROUND: The impact of polyvascular disease (peripheral arterial disease [PAD] and cerebrovascular disease [CVD]) on long-term cardiovascular outcomes among older patients with acute myocardial infarction has not been well studied. METHODS AND RESULTS: ... Full text Link to item Cite

Clopidogrel use and hospital quality in medically managed patients with non-ST-segment-elevation myocardial infarction.

Journal article Circ Cardiovasc Qual Outcomes · July 1, 2012 BACKGROUND: Clopidogrel prescription is a class I guideline recommendation for medically managed patients with non-ST-segment-elevation myocardial infarction (NSTEMI). However, clopidogrel has historically been underused in this population. We evaluated co ... Full text Link to item Cite

Safety and effectiveness of antithrombotic strategies in older adult patients with atrial fibrillation and non-ST elevation myocardial infarction.

Journal article Am Heart J · April 2012 BACKGROUND: We aimed to study the comparative safety and effectiveness of various antithrombotic treatment strategies among older adults with non-ST elevation myocardial infarction (NSTEMI) and atrial fibrillation (AF). METHODS: Using the CRUSADE registry ... Full text Link to item Cite

Comparison of clinical characteristics, treatments and outcomes of patients with ST-elevation acute myocardial infarction with versus without new or presumed new left bundle branch block (from NCDR®).

Journal article Am J Cardiol · February 15, 2012 Guidelines recommend urgent reperfusion for patients with new left bundle branch block (LBBB), similar to patients with ST-segment elevation myocardial infarction (STEMI). However, there are limited contemporary data comparing these 2 groups of patients. P ... Full text Link to item Cite

Comparison of the prognostic value of peak creatine kinase-MB and troponin levels among patients with acute myocardial infarction: a report from the Acute Coronary Treatment and Intervention Outcomes Network Registry-get with the guidelines.

Journal article Clin Cardiol · 2012 BACKGROUND: Although peak creatine kinase-myocardial band (CK-MB) and troponin levels have been correlated with mortality among patients with acute myocardial infarction (AMI), the independent prognostic implications of these markers have not been compared ... Full text Link to item Cite

Postoperative inotrope and vasopressor use following CABG: outcome data from the CAPS-care study.

Journal article J Card Surg · November 2011 BACKGROUND/AIM: Limited clinical data exist to guide practice patterns and evidence-based use of inotropes and vasopressors following coronary artery bypass grafting (CABG). METHODS: Contemporary Analysis of Perioperative Cardiovascular Surgical Care (CAPS ... Full text Link to item Cite

Use of emergency medical service transport among patients with ST-segment-elevation myocardial infarction: findings from the National Cardiovascular Data Registry Acute Coronary Treatment Intervention Outcomes Network Registry-Get With The Guidelines.

Journal article Circulation · July 12, 2011 BACKGROUND: Activation of emergency medical services (EMS) is critical for the early triage and treatment of patients experiencing ST-segment-elevation myocardial infarction, yet data regarding EMS use and its association with subsequent clinical care are ... Full text Link to item Cite

Association of door-in to door-out time with reperfusion delays and outcomes among patients transferred for primary percutaneous coronary intervention.

Journal article JAMA · June 22, 2011 CONTEXT: Patients with ST-elevation myocardial infarction (STEMI) requiring interhospital transfer for primary percutaneous coronary intervention (PCI) often have prolonged overall door-to-balloon (DTB) times from first hospital presentation to second hosp ... Full text Link to item Cite

Temporal trends and practice variations in clopidogrel loading doses in patients with non-ST-segment elevation myocardial infarction, from the National Cardiovascular Data Registry.

Journal article Am Heart J · April 2011 BACKGROUND: A higher loading dose of clopidogrel achieves a more rapid and consistent degree of platelet inhibition than standard dosing, although the clinical benefit of higher doses has not been clearly established. The use of the different doses in clin ... Full text Link to item Cite

Fifteen-year outcome trends for valve surgery in North America.

Journal article Ann Thorac Surg · March 2011 BACKGROUND: Although results in valvular heart surgery may be improving, too few cases are available in most centers to quantify changes, especially for uncommon procedural categories. This study examined comprehensively national trends in valve surgery ou ... Full text Link to item Cite

Randomized trial of targeted performance feedback to facilitate quality improvement in acute myocardial infarction care.

Journal article Circ Cardiovasc Qual Outcomes · January 1, 2011 BACKGROUND: Efforts to improve quality of care for patients with acute myocardial infarction (AMI) are a national priority. To date, there have been few studies that have prospectively evaluated hospital quality improvement (QI) interventions. METHODS AND ... Full text Link to item Cite

Predictors of mitral valve repair: clinical and surgeon factors.

Journal article Ann Thorac Surg · December 2010 BACKGROUND: Mitral valve repair is acknowledged as desirable and superior to replacement for virtually all mitral pathology. Utilizing The Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database (ACSD), a multivariable model was created that incl ... Full text Link to item Cite

Current outcomes of simultaneous carotid endarterectomy and coronary artery bypass graft surgery in North America.

Journal article World J Surg · October 2010 OBJECTIVE: Management of patients with concomitant carotid and coronary artery disease has been controversial. Divergent strategies have been employed, including simultaneous carotid endarterectomy and coronary bypass (SCC) versus various staged procedures ... Full text Link to item Cite

Congenital heart surgery outcomes in Down syndrome: analysis of a national clinical database.

Journal article Pediatrics · August 2010 OBJECTIVE: We describe patient characteristics and postoperative morbidity and mortality rates for patients with Down syndrome undergoing congenital heart disease surgery. METHODS: This retrospective cohort study used the Society of Thoracic Surgeons Conge ... Full text Link to item Cite

Center variation and outcomes associated with delayed sternal closure after stage 1 palliation for hypoplastic left heart syndrome.

Journal article J Thorac Cardiovasc Surg · May 2010 OBJECTIVE: There is debate whether primary or delayed sternal closure is the best strategy after stage 1 palliation for hypoplastic left heart syndrome. We describe center variation in delayed sternal closure after stage 1 palliation and associated outcome ... Full text Link to item Cite

The impact of induction therapy on morbidity and operative mortality after resection of primary lung cancer.

Journal article The Journal of thoracic and cardiovascular surgery · April 2010 ObjectiveUse and operative results of neoadjuvant therapy before major elective resection for primary lung cancer were examined in the Society of Thoracic Surgeons General Thoracic Surgical Database.MethodsLobectomy and pneumonectomy for ... Full text Cite

Variation in perioperative vasoactive therapy in cardiovascular surgical care: data from the Society of Thoracic Surgeons.

Journal article Am Heart J · July 2009 BACKGROUND: The appropriate use of vasoactive cardiovascular drugs in high-risk coronary artery bypass grafting (CABG) patients has not been well characterized. METHODS: We performed a detailed chart analysis on 2,390 randomly selected patients undergoing ... Full text Link to item Cite

Mayo Clinic Risk Score for percutaneous coronary intervention predicts in-hospital mortality in patients undergoing coronary artery bypass graft surgery.

Journal article Circulation · January 22, 2008 BACKGROUND: Current risk models predict in-hospital mortality after either coronary artery bypass graft surgery or percutaneous coronary interventions separately, yet the overlap suggests that the same variables can define the risks of alternative coronary ... Full text Link to item Cite

Uterine artery embolization for treatment of leiomyomata: long-term outcomes from the FIBROID Registry.

Journal article Obstet Gynecol · January 2008 OBJECTIVE: To assess long-term clinical outcomes of uterine artery embolization across a wide variety of practice settings in a large patient cohort. METHODS: The Fibroid Registry for Outcomes Data (FIBROID) for Uterine Embolization was a 3-year, single-ar ... Full text Link to item Cite