Current Duke Appointments & Affiliations
Professor of Medicine
·
2025 - Present
Medicine, Medical Oncology,
Medicine
Recent Scholarly Works
Prolonged BCR::ABL1 induction in the SCL-tTA mouse recapitulates gene expression signatures and therapeutic vulnerabilities of primary imatinib-resistant chronic myeloid leukaemia.
Journal article Leukemia · July 2026 Full text Link to item CiteCorrection: Shyamsunder et al. THZ531 Induces a State of BRCAness in Multiple Myeloma Cells: Synthetic Lethality with Combination Treatment of THZ 531 with DNA Repair Inhibitors. Int. J. Mol. Sci. 2022, 23, 1207.
Journal article Int J Mol Sci · June 12, 2026 In the original publication [...]. ... Full text Link to item CiteETC-501 Is a Brain-Penetrant MNK Inhibitor That Potentiates TMZ-Induced Senescence and Sensitizes Glioblastoma Cells to Senolytic Therapy.
Journal article Cancer Res · April 15, 2026 UNLABELLED: Glioblastoma (GBM) is the deadliest primary brain tumor in adults, with a median survival of only 15 months and fewer than 10% of patients surviving beyond 5 years. Despite aggressive multimodal therapies, including surgical resection, radiatio ... Full text Link to item CiteEducation
University of Cambridge (United Kingdom) ·
1987
M.B.B.Ch.