Current Appointments & Affiliations
Professor of Medicine
·
2025 - Present
Medicine, Medical Oncology,
Medicine
Recent Publications
Charting New Paths in Cancer Research: Insights from the Frontiers in Cancer Science Conference 2024.
Journal Article Cancer Res · August 1, 2025 The 16th annual Frontiers in Cancer Science conference convened leading experts to discuss the latest developments in cancer research. Key research themes included mechanisms of treatment resistance and innovative strategies to target resistant cancer cell ... Full text Link to item CiteChronic inflammation deters natural killer cell fitness and cytotoxicity in myeloid leukemia.
Journal Article Blood Adv · February 25, 2025 Natural killer (NK) cells play an integral role in immunosurveillance against myeloid malignancies, with their mature phenotype and abundance linked to prolonged treatment-free remission in chronic myeloid leukemia (CML). However, NK cell function is suppr ... Full text Link to item CiteThe BIM deletion polymorphism potentiates the survival of leukemia stem and progenitor cells and impairs response to targeted therapies.
Journal Article Leukemia · January 2025 One sixth of human cancers harbor pathogenic germline variants, but few studies have established their functional contribution to cancer outcomes. Here, we developed a humanized mouse model harboring a common East Asian polymorphism, the BIM deletion polym ... Full text Link to item CiteEducation, Training & Certifications
University of Cambridge (United Kingdom) ·
1987
M.B.B.Ch.