Current Appointments & Affiliations
Professor of Medicine
·
2025 - Present
Medicine, Medical Oncology,
Medicine
Recent Publications
ETC-501 Is a Brain-Penetrant MNK Inhibitor That Potentiates TMZ-Induced Senescence and Sensitizes Glioblastoma Cells to Senolytic Therapy.
Journal Article Cancer Res · April 15, 2026 UNLABELLED: Glioblastoma (GBM) is the deadliest primary brain tumor in adults, with a median survival of only 15 months and fewer than 10% of patients surviving beyond 5 years. Despite aggressive multimodal therapies, including surgical resection, radiatio ... Full text Link to item CiteCharting New Paths in Cancer Research: Insights from the Frontiers in Cancer Science Conference 2024.
Journal Article Cancer Res · August 1, 2025 The 16th annual Frontiers in Cancer Science conference convened leading experts to discuss the latest developments in cancer research. Key research themes included mechanisms of treatment resistance and innovative strategies to target resistant cancer cell ... Full text Link to item CiteChronic inflammation deters natural killer cell fitness and cytotoxicity in myeloid leukemia.
Journal Article Blood Adv · February 25, 2025 Natural killer (NK) cells play an integral role in immunosurveillance against myeloid malignancies, with their mature phenotype and abundance linked to prolonged treatment-free remission in chronic myeloid leukemia (CML). However, NK cell function is suppr ... Full text Link to item CiteEducation
University of Cambridge (United Kingdom) ·
1987
M.B.B.Ch.