Scholars@Duke
Tarek Bou Dargham

Tarek Bou Dargham

House Staff
Medicine

Scholarly Works

Stroke Risk After Bioprosthetic Aortic Valve Replacement in Aortic Stenosis: Systematic Review and Meta-Analysis.

Journal article Stroke · June 2026 BACKGROUND: Stroke is a possible complication after bioprosthetic aortic valve replacement (AVR) for severe aortic stenosis (AS), impacting morbidity and mortality. Accurate estimates of the proportion of individuals who experience stroke within and beyond ... Full text Open Access Link to item Cite

Human Cytomegalovirus as a Therapeutic Target in Glioma Stem Cells.

Journal article Cells · March 24, 2026 Glioblastoma is the most aggressive tumor among gliomas, and recurrence remains inevitable despite aggressive therapies. Resistance to existing treatment modalities is attributed in part to the presence of glioma stem cells, which comprise a distinct cell ... Full text Open Access Link to item Cite

Prognostic Implications of Pneumothorax and Pneumomediastinum in COVID-19 Pneumonia: A Cross-Sectional Analysis

Journal article The Open Respiratory Medicine Journal · February 2, 2026 IntroductionThe prognostic implications of developing pneumothorax (PT) or pneumomediastinum (PM) in COVID-19 pneumonia remain a topic of debate, with current literature s ... Full text Cite

Neurocognitive outcomes in patients with brain metastases: a systematic review.

Journal article Lancet Oncol · December 2025 Multimodality therapy, including surgery, radiotherapy, and systemic therapy, has significantly improved overall survival for patients with brain metastases. However, treatment-related neurocognitive sequelae remain a major challenge in survivorship. Altho ... Full text Link to item Cite

Changing Landscape of Invasive Pneumococcal Disease Serotypes and Antimicrobial Resistance Following Pneumococcal Conjugate Vaccine Introduction in the Middle East and North Africa Region: A Systematic Review

Journal article Vaccines · August 29, 2025 Background/Objectives: Pneumococcal conjugate vaccines (PCVs) have significantly reduced invasive pneumococcal disease (IPD) globally. We conducted a systematic review to assess whether serotype and antimicrobial resistance trends in the Middle Eas ... Full text Cite

The clinical impact of 16S ribosomal RNA PCR and sequencing in the identification of bacterial infections: a 7-year report from a Lebanese tertiary care center

Journal article Frontiers in Cellular and Infection Microbiology · August 7, 2025 IntroductionThe identification of bacterial pathogens in the clinical setting is essential for providing optimal care and improving outcomes. The primary objective of this study was to assess the performance of th ... Full text Cite

Minorities are under-reported and females are under-represented in stroke motor recovery trials.

Journal article Top Stroke Rehabil · March 2025 BACKGROUND: Inclusion of diverse patient populations in stroke rehabilitation clinical trials is key for generalizability and detecting differences in subgroups. The aim of this study was to assess the reporting and inclusion of race, ethnicity, and sex in ... Full text Link to item Cite

Insomnia and Mental Health Outcomes After Catastrophic Disasters: A Cross-Sectional Study Examining the Long-Term Effects of the Beirut Port Explosion.

Journal article Neuropsychiatric disease and treatment · January 2025 BackgroundThe August 4, 2020 Beirut port explosion caused widespread destruction and psychological distress. This study evaluates long-term effects on sleep disturbances and trauma, focusing on proximity to the blast site.MethodsWe survey ... Full text Cite

Psychotropic Medication and Substance use among Lebanese Medical and Nonmedical Students: A Cross-sectional Study

Journal article Lebanese Journal of Mental Health · January 2025 Background:Students in Lebanon generally experience significant stress due to the country’s economic and political instability. Medical students, in particular, are at ris ... Full text Cite

Epidemiology, Pathophysiology, and Management of Cancer-Associated Ischemic Stroke.

Journal article Cancers (Basel) · November 29, 2024 Cancer and stroke are leading causes of global disability and mortality. With improvements in cancer-associated mortality and advancements in treatment of active malignancy, it is more common to encounter patients with ischemic stroke and active malignancy ... Full text Open Access Link to item Cite

TMIC-45. CYTOMEGALOVIRUS PP65 ANTIGEN EXPRESSION FOLLOWING PP65-SPECIFIC DENDRITIC CELL VACCINATION IN MATCHED PRIMARY AND RECURRENT GLIOBLASTOMA SPECIMENS

Conference Neuro-Oncology · November 11, 2024 AbstractBACKGROUNDHuman cytomegalovirus (HCMV) expression in glioblastoma (GBM) has been corroborated by multiple independent laborato ... Full text Cite

Using Machine Learning and Electronic Health Records to Identify Neuropsychiatric Risk Scores for Delirium in ICU and General Hospital Settings.

Journal article Neuropsychiatric disease and treatment · January 2024 ObjectiveDelirium is a common and acute neuropsychiatric syndrome that requires timely intervention to prevent its associated morbidity and mortality. Yet, its diagnosis and symptoms are often overlooked due to its variable clinical presentation a ... Full text Cite

Treatment Strategies for Residual Disease following Neoadjuvant Chemotherapy in Patients with Early-Stage Breast Cancer.

Journal article Current oncology (Toronto, Ont.) · August 2022 Breast cancer continues to be the most diagnosed cancer among women worldwide. Neoadjuvant chemotherapy is the standard of care for breast cancer patients with locally advanced disease and patients with poor pathological features, such as triple-negative ( ... Full text Cite

A scoping review on acute gastrointestinal surgical complications in immunocompromised pediatric patients

Journal article Annals of Pediatric Surgery · July 6, 2022 AbstractBackgroundGastrointestinal complications are becoming increasingly more common and pose a significant risk on the health of children with compromised immunity caused by various eti ... Full text Cite