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Tatiana Segura

Professor of Biomedical Engineering
Biomedical Engineering
534 Research Drive, Durham, NC 27708

Research Interests


The design of biomaterials to promote endogenous repair and reducing inflammation through the design of the geometry of the material, and delivering genes, proteins and drugs.

Selected Grants


Investigating mechanisms of cell volume regulation in the zebrafish notochord

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2028

Medical Scientist Training Program

Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of General Medical Sciences · 2022 - 2027

University Training Program in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institutes of Health · 1994 - 2027

Development and Application of New Ionization Methods for Biological Mass Spectrometry

ResearchPrincipal Investigator · Awarded by North Carolina State University · 2022 - 2026

Duke Center for Advancement of Child Health (CAtCH).

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026

Investigating mechanisms of cell volume regulation in the zebrafish notochord

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2028

Medical Scientist Training Program

Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of General Medical Sciences · 2022 - 2027

University Training Program in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institutes of Health · 1994 - 2027

Development and Application of New Ionization Methods for Biological Mass Spectrometry

ResearchPrincipal Investigator · Awarded by North Carolina State University · 2022 - 2026

Duke Center for Advancement of Child Health (CAtCH).

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026

Engineering Strategies for Replenishable Drug-Eluting Transplants

ResearchCollaborator · Awarded by American Society of Transplant Surgeons · 2023 - 2025

Pharmacological Sciences Training Grant

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025

Engineering Adaptive Immune Responses from Hydrogel Scaffolds to Promote Tissue Regeneration

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2025

Biomaterials to promote synapse formation after stroke

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2024

VEGF ligand presentation and therapeutic angiogenesis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2024

An injectable biomaterial for transplant tolerance

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Association of Women Surgeons · 2023 - 2024

Non-Canonical Pathways for Electrogene Transfer

ResearchCo Investigator · Awarded by National Institutes of Health · 2018 - 2023

Brain repair after stroke

ResearchPrincipal Investigator · Awarded by Centre for Effective Altruism · 2022 - 2023

Cell and Gene Replacement Strategies for Arginase Deficiency

ResearchPrincipal Investigator · Awarded by University of California - Los Angeles · 2018 - 2022

Pharmacological Sciences Training Program

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by National Institutes of Health · 1975 - 2020

Engineering Injectable Microporous Hydrogels for Brain Repair

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2020

External Relationships


  • BESE Biologics
  • Tempo therapeutics

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.