Scholars@Duke
Tatiana Segura

Tatiana Segura

Robert Plonsey Distinguished Professor of Biomedical Engineering
Biomedical Engineering
534 Research Drive, Durham, NC 27708

Scholarly Works - Preprints

Highly porous granular hydrogels reinforced by electrospun hydrogel fibers for long-term stability

Preprint · 2024 Granular hydrogels (GHs) formed from hydrogel microparticles (HMPs) possess inherent, microscale porosity. In GHs including microporous annealed particle (MAP) hydrogels as well as unannealed GHs, increases in pore size and total porosity correlate with en ... Full text Cite

Engineering the microstructure and spatial bioactivity of MAP scaffolds in vitro instructs neovascularization in vivo

Preprint · 2023 In tissues where the vasculature is either lacking or abnormal, biomaterials can be designed to promote vessel formation and enhance tissue repair. In this work, we independently tune the microstructure and bioactivity of microporous annealed particle (MAP ... Full text Cite

Spatial confinement modulates macrophage response in microporous annealed particle (MAP) scaffolds

Preprint · 2022 Macrophages are essential in the initiation, maintenance, and transition of inflammatory processes like foreign body response and wound healing. Mounting evidence suggests that physical factors also modulate macrophage activation in vitro and in vivo . 2 ... Full text Cite