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Thomas Burke

Manager, Systems Project
The Precision Medicine Program
Duke Box 3382, Durham, NC 27710
101 Science Drive, CIEMAS Bldg. Rm. 2177B, Durham, NC 27708

Current Appointments & Affiliations


Manager, Systems Project The Precision Medicine Program, Medicine
Manager, Systems Project Medicine, Clinical Science Departments

Recent Publications


Age-associated differences in mucosal and systemic host responses to SARS-CoV-2 infection.

Journal Article Nat Commun · March 10, 2025 Age is among the strongest risk factors for severe outcomes from SARS-CoV-2 infection. Here we describe upper respiratory tract (URT) and peripheral blood transcriptomes of 202 participants (age range of 1 week to 83 years), including 137 non-hospitalized ... Full text Open Access Link to item Cite

A Rapid Host Response Blood Test for Bacterial/Viral Infection Discrimination Using a Portable Molecular Diagnostic Platform.

Journal Article Open Forum Infect Dis · January 2025 BACKGROUND: Difficulty discriminating bacterial versus viral etiologies of infection drives unwarranted antibacterial prescriptions and, therefore, antibacterial resistance. METHODS: Utilizing a rapid portable test that measures peripheral blood host gene ... Full text Link to item Cite

Implementation of a Prospective Index-Cluster Sampling Strategy for the Detection of Presymptomatic Viral Respiratory Infection in Undergraduate Students.

Journal Article Open Forum Infect Dis · March 2024 BACKGROUND: Index-cluster studies may help characterize the spread of communicable infections in the presymptomatic state. We describe a prospective index-cluster sampling strategy (ICSS) to detect presymptomatic respiratory viral illness and its implement ... Full text Link to item Cite
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Recent Grants


Combined pathogen and host-based diagnostic to identify etiology of lower respiratory tract infection

ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2028

Molecular predictors of cardiovascular events and resilience in chronic coronary artery disease

ResearchProject Leader · Awarded by NYU Langone Medical Center · 2023 - 2028

International Clinical Administrative Core (Clinical Core)

ResearchLaboratory Director · Awarded by University of California - Los Angeles · 2023 - 2028

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External Links


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