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Thuy Le

Associate Professor of Medicine
Medicine, Infectious Diseases
Duke Box 102359, Durham, NC 27710, Durham, NC 27710
315 Trent Drive, Room #257, Durham, NC 27710

Current Duke Appointments & Affiliations


Associate Professor of Medicine · 2024 - Present Medicine, Infectious Diseases, Medicine
Associate Professor of Molecular Genetics and Microbiology · 2019 - Present Molecular Genetics and Microbiology, Basic Science Departments
Affiliate, Duke Global Health Institute · 2019 - Present Duke Global Health Institute, University Institutes and Centers

Recent News Items


Published August 10, 2026
Why Is This Fungal STI Going Underdiagnosed?
Published October 16, 2025
Infographics about Antimicrobial Stewardship in Talaromyces marneffei, created by the International Society for Infectious Diseases
Published February 1, 2025
Diagnosing the invasive fungal infection talaromycosis earlier to save lives

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Recent Scholarly Works


In Vitro Evaluation of Olorofim and Amphotericin B Combination Therapy Against Talaromyces marneffei.

Journal article J Fungi (Basel) · June 17, 2026 The dimorphic fungus Talaromyces marneffei causes talaromycosis, a life-threatening fungal disease with limited treatment options. Olorofim, a first-in-class orotomide antifungal that targets pyrimidine synthesis essential for fungal growth, has low minimu ... Full text Link to item Cite

Histoplasmosis: a missing piece in the global efforts to end HIV deaths.

Journal article Lancet HIV · May 2026 Histoplasmosis is a leading opportunistic infection and cause of mortality in people with advanced HIV disease. Yet, histoplasmosis is largely neglected in the global HIV response. Previously considered endemic only in the region of the Americas, histoplas ... Full text Link to item Cite
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Recent Grants


Liposomal Amphotericin B and Flucytosine Antifungal Strategies for Talaromycosis (LAmB-FAST) - R01

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2031

Interdisciplinary Research Training Program in AIDS

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2010 - 2030

Tri-Institutional Molecular Mycology and Pathogenesis Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029

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Education


University of Oxford (United Kingdom) · 2016 D.Phil.
University of Arizona, College of Medicine · 2002 M.D.