Skip to main content

Uchechukwu Ikeaba

Biostatistician II
Duke Clinical Research Institute
300 W. Morgan Street, Durham, NC 27701

Scholarly Works


Predictive factors for care intensification in a no co-pay physical therapy model for musculoskeletal pain.

Journal article BMC Health Serv Res · March 26, 2026 BACKGROUND: Musculoskeletal pain conditions are prevalent and costly, with practice guidelines consistently recommending non-pharmacologic interventions as first-line treatments. Physical therapists are common providers of non-pharmacologic pain care, and ... Full text Link to item Cite

Public Health.

Journal article Alzheimers Dement · December 2025 BACKGROUND: About one in three COVID-19 patients experience neurological problems; and acute ischemic stroke (AIS) is one of the common comorbidities of COVID-19. As stroke doubles the risk of dementia, AIS patients with COVID-19 infection may experience e ... Full text Link to item Cite

Clinical Outcomes and Health Care Costs in Patients Hospitalized With Heart Failure and Transthyretin Amyloid Cardiomyopathy: Findings From GWTG-HF.

Journal article J Card Fail · November 8, 2025 BACKGROUND: The real-world clinical and economic burden of transthyretin amyloid cardiomyopathy (ATTR-CM) is not well characterized. Prior studies have often been limited by uncertain generalizability or reliance on administrative claims data, which can la ... Full text Link to item Cite

Episode of Care Characteristics Following Implementation of a No Copay Physical Therapy Program for Musculoskeletal Conditions.

Journal article Phys Ther · November 3, 2025 IMPORTANCE: New care models promoting early access to physical therapy by reducing or eliminating copays are emerging. Few studies have compared health care use in these programs to other care pathways across musculoskeletal conditions. OBJECTIVE: The obje ... Full text Link to item Cite

Self-reported disability trajectories and their predictors among patients receiving care by physical therapists for musculoskeletal conditions: a retrospective analysis of registry data.

Journal article BMJ Open · June 20, 2025 OBJECTIVES: To identify clustered trajectories of self-reported disability following the initiation of care by a physical therapist in outpatient orthopaedic settings and to determine baseline factors that distinguish between different trajectories. DESIGN ... Full text Link to item Cite

Early Adoption of Sodium-Glucose Cotransporter-2 Inhibitor in Patients Hospitalized With Heart Failure With Mildly Reduced or Preserved Ejection Fraction.

Journal article JAMA Cardiol · January 1, 2025 IMPORTANCE: Sodium-glucose cotransporter-2 inhibitors (SGLT2is) are the first therapy shown to improve clinical outcomes for patients with heart failure (HF) and a left ventricular ejection fraction (LVEF) greater than 40%. Nationwide adoption of SGLT2is i ... Full text Link to item Cite

Cause-Specific Health Care Costs Following Hospitalization for Heart Failure and Cost Offset With SGLT2i Therapy.

Journal article JACC Heart Fail · August 2024 BACKGROUND: Little is known regarding differences in cause-specific costs between heart failure (HF) with ejection fraction (EF) ≤40% vs >40%, and potential cost implications of sodium glucose co-transporter 2 inhibitor (SGLT2i) therapy. OBJECTIVES: This s ... Full text Link to item Cite

Torsemide Versus Furosemide After Discharge in Patients Hospitalized With Heart Failure Across the Spectrum of Ejection Fraction: Findings From TRANSFORM-HF.

Journal article Circ Heart Fail · March 2024 BACKGROUND: The TRANSFORM-HF trial (Torsemide Comparison With Furosemide for Management of Heart Failure) found no significant difference in all-cause mortality or hospitalization among patients randomized to a strategy of torsemide versus furosemide follo ... Full text Link to item Cite

Contemporary Use of Sodium-Glucose Cotransporter-2 Inhibitor Therapy Among Patients Hospitalized for Heart Failure With Reduced Ejection Fraction in the US: The Get With The Guidelines-Heart Failure Registry.

Journal article JAMA Cardiol · July 1, 2023 IMPORTANCE: Clinical guidelines for patients with heart failure with reduced ejection fraction (HFrEF) strongly recommend treatment with a sodium-glucose cotransporter-2 inhibitor (SGLT2i) to reduce cardiovascular mortality or HF hospitalization. Nationwid ... Full text Link to item Cite

Quality of Care and Outcomes Among Patients Hospitalized for Heart Failure in Rural vs Urban US Hospitals: The Get With The Guidelines-Heart Failure Registry.

Journal article JAMA Cardiol · April 1, 2023 IMPORTANCE: Prior studies have suggested patients with heart failure (HF) from rural areas have worse clinical outcomes. Contemporary differences between rural and urban hospitals in quality of care and clinical outcomes for patients hospitalized for HF re ... Full text Link to item Cite

Self-Care of African Immigrant Adults with Chronic Illness.

Journal article Clinical nursing research · March 2022 This cross-sectional study aims to describe the self-care of adult African immigrants in the US with chronic illness and explore the relationship between acculturation and self-care. A total of 88 African immigrants with chronic illness were enrolled. Self ... Full text Cite

Leveraging Electronic Health Records and Machine Learning to Tailor Nursing Care for Patients at High Risk for Readmissions.

Journal article Journal of nursing care quality · January 2020 BackgroundElectronic health record-derived data and novel analytics, such as machine learning, offer promising approaches to identify high-risk patients and inform nursing practice.PurposeThe aim was to identify patients at risk for readm ... Full text Cite