Journal articleNature methods · January 2026
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Living organisms develop their shape through the interplay of gene expression and mechanics. While atlases of static samples characterize cell fates and gene regulation, understanding dynamic shape changes requires live imaging. Here we present DynamicAtla ...
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Preprint · 2025
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During gastrulation, a sequence of complex processes transforms the blastula into a multi-layered embryo. Fixed sample analysis has revealed much about how genetic signaling cascades determine the major body axes and organize cell fate patterns into the ge ...
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Journal articleCurrent biology : CB · August 2023
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Bilateral symmetry defines much of the animal kingdom and is crucial for numerous functions of bilaterian organisms. Genetic approaches have discovered highly conserved patterning networks that establish bilateral symmetry in early embryos,1 but ...
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Preprint · 2022
During morphogenesis, diverse cell-scale and tissue-scale processes couple to dynamically sculpt organs. In this coupling, genetic expression patterns and biochemical signals regulate and respond to mechanical deformations to ensure reproducible and robust ...
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https://orcid.org/0000-0003-0995-1585