Xi-Liang Gu

Journal Article Proceedings of the National Academy of Sciences of the United States of America · December 2009 Health care is a crucial factor in US economic growth, because growing health care costs have made US corporations less competitive than their counterparts in countries where central governments assume most of those costs. In this paper we illustrate a sec ... Full text Cite

NIH funding trajectories and their correlations with US health dynamics from 1950 to 2004.

Journal Article Proceedings of the National Academy of Sciences of the United States of America · July 2009 To determine optimal future National Institutes of Health (NIH) funding levels, the longitudinal correlation of the level of investment in NIH research with population changes in the risk of specific diseases should be analyzed. This is because NIH researc ... Full text Cite

Cohort changes in active life expectancy in the U.S. elderly population: experience from the 1982-2004 National Long-Term Care Survey.

Journal Article The journals of gerontology. Series B, Psychological sciences and social sciences · September 2008 ObjectivesTo understand declines in chronic disability prevalence in the U.S. elderly population, we examined cohort changes in active life expectancy, a health measure relating population disability and longevity dynamics.MethodsWe compu ... Full text Cite

Molecular basis of CNS aging, frailty, fitness and longevity: Amodel based on cellular energetics

Chapter · March 1, 2008 The concept of frailty, a decrease in physical function and increasing vulnerability to morbidity and death, is central to the biological study of aging (Fried et al., 2001; Walston, 2004). Genetics, epigenetics, free radicals, aging, disease, and cellular ... Cite

Labor force participation and human capital increases in an aging population and implications for U.S. research investment.

Journal Article Proceedings of the National Academy of Sciences of the United States of America · June 2007 The proportion of the United States labor force >/=65 years of age is projected to increase between 2004 and 2014 by the passing of age 65 of the large post-World War II baby boom cohorts starting in 2010 and their greater longevity, income, education, and ... Full text Cite

Medicare cost effects of recent U.S. disability trends in the elderly: future implications.

Journal Article Journal of aging and health · June 2007 ObjectiveThe authors examine how trends in disability prevalence and in inflation-adjusted per capita, per annum Medicare costs, 1982 to 1999 and 1989 to 1999, affected total Medicare costs projected to 2004 and 2009.MethodTo describe dis ... Full text Cite

Change in chronic disability from 1982 to 2004/2005 as measured by long-term changes in function and health in the U.S. elderly population.

Journal Article Proceedings of the National Academy of Sciences of the United States of America · November 2006 Changes in the health and functioning of the Medicare-enrolled population aged 65+ are tracked by using the 1982-2004/2005 National Long-Term Care Surveys. We found a significant rate of decline in the prevalence of chronic disability that accelerated from ... Full text Cite

Long-term trends in life expectancy and active life expectancy in the United States

Journal Article Population and Development Review · March 1, 2006 Changes in life expectancy and in active life expectancy may have effects on the fiscal integrity of both the Social Security and Medicare programs. Analysis of the fiscal stability of these programs shows that the most serious problem may be the growth of ... Full text Cite

Declining prevalence of dementia in the U.S. elderly population.

Journal Article Advances in gerontology = Uspekhi gerontologii · January 2005 A decline in chronic disability prevalence occurred 1982 to 1999 in the U.S. elderly population parallel to declines in severe cognitive impairment. Comparative analysis of factors contributing to the incidence of dementia led us to suggest explanations fo ... Cite

Fuzzy set analyses of genetic determinants of health and disability status.

Journal Article Statistical methods in medical research · October 2004 Analyses of complex genotype-phenotype relations require new statistical procedures because of the potentially high dimensionability of those relations which are expressed with both measurement error and stochasticity in the correlation function. We propos ... Full text Cite

Changes in the prevalence of chronic disability in the United States black and nonblack population above age 65 from 1982 to 1999.

Journal Article Proceedings of the National Academy of Sciences of the United States of America · May 2001 Survey evidence through the early 1990s generally suggests a reduction in disability in the elderly population of the United States. Because the evidence is not fully consistent, several authors have speculated about whether disability declines will contin ... Full text Cite