Current Duke Appointments & Affiliations
Assistant Professor of Biostatistics & Bioinformatics
·
2020 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Assistant Professor in the Department of Pierre R. Lamond Department of Electrical and Computer Engineering
·
2026 - Present
Pierre R. Lamond Department of Electrical and Computer Engineering,
Pratt School of Engineering
Recent Scholarly Works
PreTSA: computationally efficient modeling of temporal and spatial gene expression patterns.
Journal article Genome Biol · February 12, 2026 Modeling temporal and spatial gene expression patterns in large-scale single-cell and spatial transcriptomics data is a computationally intensive task. We present PreTSA, a method that offers computational efficiency in modeling these patterns and is appli ... Full text Link to item CiteSingle-cell and spatial detection of senescent cells using DeepScence.
Journal article Cell Genom · December 10, 2025 Accurately identifying senescent cells is essential for studying their spatial and molecular features. We developed DeepScence, a method based on deep neural networks, to identify senescent cells in single-cell and spatial transcriptomics data. DeepScence ... Full text Link to item CiteIdentifying cell-type-specific spatially variable genes with ctSVG.
Journal article Genome Biol · December 8, 2025 Spatially variable genes (SVGs) reveal the molecular and functional heterogeneity of cells across different spatial regions of a tissue. Sample-wide SVGs identified by existing methods largely overlap with cell-type marker genes derived from single-cell ge ... Full text Open Access Link to item CiteRecent Grants
Computational Biology and Bioinformatics Training Grant
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2026 - 2031computational methods for spatial transcriptomics
ResearchPrincipal Investigator · Awarded by National Institute of General Medical Sciences · 2024 - 2029Advancing Technologies for Spatiotemporal Omics in Live Tissue
ResearchPrincipal Investigator · Awarded by University of Washington · 2026 - 2028View All Grants
Education
Johns Hopkins Unversity, Bloomberg School of Public Health ·
2020
Ph.D.