Andrew Wang

Journal article JAMA · April 25, 2012 Featured Publication CONTEXT: Infection of implantable cardiac devices is an emerging disease with significant morbidity, mortality, and health care costs. OBJECTIVES: To describe the clinical characteristics and outcome of cardiac device infective endocarditis (CDIE) with att ... Full text Link to item Cite

Effects of atrial fibrillation on treatment of mitral regurgitation in the EVEREST II (Endovascular Valve Edge-to-Edge Repair Study) randomized trial.

Journal article J Am Coll Cardiol · April 3, 2012 Featured Publication OBJECTIVES: The purpose of this study was to characterize patients with mitral regurgitation (MR) and atrial fibrillation (AF) treated percutaneously using the MitraClip device (Abbott Vascular, Abbott Park, Illinois) and compare the results with surgery i ... Full text Link to item Cite

Association between valvular surgery and mortality among patients with infective endocarditis complicated by heart failure.

Journal article JAMA · November 23, 2011 Featured Publication CONTEXT: Heart failure (HF) is the most common complication of infective endocarditis. However, clinical characteristics of HF in patients with infective endocarditis, use of surgical therapy, and their associations with patient outcome are not well descri ... Full text Link to item Cite

Alcohol septal ablation for the treatment of hypertrophic obstructive cardiomyopathy. A multicenter North American registry.

Journal article J Am Coll Cardiol · November 22, 2011 Featured Publication OBJECTIVES: The purpose of the study is to identify the predictors of clinical outcome (mortality and survival without repeat septal reduction procedures) of alcohol septal ablation for the treatment of patients with hypertrophic obstructive cardiomyopathy ... Full text Link to item Cite

Percutaneous heart valve replacement for aortic stenosis: state of the evidence.

Journal article Ann Intern Med · September 7, 2010 Featured Publication Surgical aortic valve replacement (SAVR) is the only treatment known to improve symptoms and survival in patients with severe, symptomatic aortic stenosis. Perioperative mortality, however, is high among many patients for whom SAVR may be indicated. Percut ... Full text Link to item Cite

Meta-analyses of septal reduction therapies for obstructive hypertrophic cardiomyopathy: comparative rates of overall mortality and sudden cardiac death after treatment.

Journal article Circ Cardiovasc Interv · April 2010 Featured Publication BACKGROUND: Septal reduction for obstructive hypertrophic cardiomyopathy may be performed by surgical myectomy or alcohol septal ablation (ASA). Unlike surgical myectomy, ASA creates an intramyocardial scar that may potentiate the risk of ventricular arrhy ... Full text Link to item Cite

Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias.

Journal article Circulation · March 2, 2010 Featured Publication BACKGROUND: The impact of early surgery on mortality in patients with native valve endocarditis (NVE) is unresolved. This study sought to evaluate valve surgery compared with medical therapy for NVE and to identify characteristics of patients who are most ... Full text Open Access Link to item Cite

Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study.

Journal article Arch Intern Med · March 9, 2009 Featured Publication BACKGROUND: We sought to provide a contemporary picture of the presentation, etiology, and outcome of infective endocarditis (IE) in a large patient cohort from multiple locations worldwide. METHODS: Prospective cohort study of 2781 adults with definite IE ... Full text Link to item Cite

Clinical problem-solving. Taken out of context.

Journal article N Engl J Med · December 4, 2008 Featured Publication Full text Link to item Cite

Contemporary clinical profile and outcome of prosthetic valve endocarditis.

Journal article JAMA · March 28, 2007 Featured Publication CONTEXT: Prosthetic valve endocarditis (PVE) is associated with significant mortality and morbidity. The contemporary clinical profile and outcome of PVE are not well defined. OBJECTIVES: To describe the prevalence, clinical characteristics, and outcome of ... Full text Link to item Cite

Early surgery in patients with infective endocarditis: a propensity score analysis.

Journal article Clin Infect Dis · February 1, 2007 Featured Publication BACKGROUND: An accurate assessment of the predictors of long-term mortality in patients with infective endocarditis is not possible using retrospective data because of inherent treatment biases and predictable imbalances in the distribution of prognostic f ... Full text Link to item Cite

Use of surgery in patients with native valve infective endocarditis: results from the International Collaboration on Endocarditis Merged Database.

Journal article Am Heart J · November 2005 Featured Publication BACKGROUND: Early surgery has been shown to be beneficial for patients with infective endocarditis (IE), yet surgery is not used in most patients. Evidence of the uncertainty around the use of surgery can be found in the wide variations in the use of cardi ... Full text Link to item Cite

The use and effect of surgical therapy for prosthetic valve infective endocarditis: a propensity analysis of a multicenter, international cohort.

Journal article Am Heart J · November 2005 Featured Publication BACKGROUND: Although surgical intervention is often used in the treatment of prosthetic valve infective endocarditis (PVIE), an understanding of its effect on survival has been limited by the biases of observational studies and lack of controlled trials. M ... Full text Link to item Cite

Early predictors of in-hospital death in infective endocarditis.

Journal article Circulation · April 13, 2004 Featured Publication BACKGROUND: Data on early determinants of outcome in infective endocarditis (IE) are limited. We evaluated the prognostic significance of early clinical characteristics in a large, prospective cohort of patients with IE. METHODS AND RESULTS: Two hundred si ... Full text Link to item Cite

Fenoldopam mesylate for the prevention of contrast-induced nephropathy: a randomized controlled trial.

Journal article JAMA · November 5, 2003 Featured Publication CONTEXT: The development of contrast-induced nephropathy in patients undergoing invasive cardiac procedures is associated with a marked increase in cardiovascular morbidity and mortality. Fenoldopam mesylate, a specific agonist of the dopamine-1 receptor, ... Full text Link to item Cite

Exercise echocardiographic comparison of pulmonary autograft and aortic homograft replacements for aortic valve disease in adults.

Journal article J Heart Valve Dis · March 2003 Featured Publication BACKGROUND AND AIM OF THE STUDY: The pulmonary autograft, or Ross procedure, has theoretical hemodynamic benefits over other aortic valve replacements. The hemodynamic performance of the pulmonary autograft and pulmonary homograft components of this proced ... Link to item Cite

Fenoldopam mesylate blocks reductions in renal plasma flow after radiocontrast dye infusion: a pilot trial in the prevention of contrast nephropathy.

Journal article Am Heart J · May 2002 Featured Publication BACKGROUND: Radiocontrast nephropathy (RCN) is a common source of acute renal failure in hospitalized patients and is associated with increased morbidity and mortality rates. Fenoldopam mesylate is a dopamine A1 receptor agonist that augments renal plasma ... Full text Link to item Cite