Scholars@Duke

• Research
• 

  Selected Grants

  • Chromatin regulation of TCR locus V(D)J recombination awarded by National Institutes of Health 2020 - 2025
  • Control of TCR Delta and TCR Alpha Rearrangement awarded by National Institutes of Health 1989 - 2021
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Naik, Abani Kanta, Aaron T. Byrd, Aaron C. K. Lucander, and Michael S. Krangel. “Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4+CD8+ thymocytes.” J Exp Med 216, no. 1 (January 7, 2019): 231–43. https://doi.org/10.1084/jem.20181402.
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    • Hao, Bingtao, Abani Kanta Naik, Akiko Watanabe, Hirokazu Tanaka, Liang Chen, Hunter W. Richards, Motonari Kondo, et al. “An anti-silencer- and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development.” J Exp Med 212, no. 5 (May 4, 2015): 809–24. https://doi.org/10.1084/jem.20142207.
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    • Naik, Abani Kanta, Abbas Hawwari, and Michael S. Krangel. “Specification of Vδ and Vα usage by Tcra/Tcrd locus V gene segment promoters.” J Immunol 194, no. 2 (January 15, 2015): 790–94. https://doi.org/10.4049/jimmunol.1402423.
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    • Naik, A. “Differential Reaction Kinetics, Cleavage Complex Formation, and Nonamer Binding Domain Dependence Dictate the Structure-Specific and Sequence-Specific Nuclease Activity of RAGs.” Journal of Molecular Biology 415, no. 3 (January 20, 2012): 475–88. https://doi.org/10.1016/j.jmb.2011.11.002.
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    • Naik, Abani Kanta, Michael R. Lieber, and Sathees C. Raghavan. “Cytosines, but Not Purines, Determine Recombination Activating Gene (RAG)-induced Breaks on Heteroduplex DNA Structures.” Journal of Biological Chemistry 285, no. 10 (March 2010): 7587–97. https://doi.org/10.1074/jbc.m109.089631.
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    • Naik, Abani Kanta, and Sathees C. Raghavan. “P1 nuclease cleavage is dependent on length of the mismatches in DNA.” Dna Repair 7, no. 8 (August 2008): 1384–91. https://doi.org/10.1016/j.dnarep.2008.04.010.
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