Research Interests
Current research areas utilize our core methodologic expertise in functional genomics, epigenetics, molecular biology, and bioinformatics and include 1) investigating the mechanisms by which epigenetic and transcriptional regulators encoded on the X and Y chromosomes influence global gene expression; 2) exploring molecular interactions between X and Y chromosome encoded factors and sex hormone signaling; 3) understanding how sex chromosome aneuploidies lead to phenotypic outcomes, such as in Turner (XO) and Klinefelter syndromes (XXY); and 4) developing novel human cell culture model systems to study sex differences in physiologically relevant contexts.
Selected Grants
Training Program in Developmental and Stem Cell Biology
Inst. Training Prgm or CMEMentor · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2001 - 2027Cell and Molecular Biology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 2021 - 2026External Relationships
- Cincinnati Children's
- NIH Center for Scientific Review
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.