Research Interests
Current research areas utilize our core methodologic expertise in functional genomics, epigenetics, molecular biology, and bioinformatics and include 1) investigating the mechanisms by which epigenetic and transcriptional regulators encoded on the X and Y chromosomes influence global gene expression; 2) exploring molecular interactions between X and Y chromosome encoded factors and sex hormone signaling; 3) understanding how sex chromosome aneuploidies lead to phenotypic outcomes, such as in Turner (XO) and Klinefelter syndromes (XXY); and 4) developing novel human cell culture model systems to study sex differences in physiologically relevant contexts.