Scholars@Duke
Ara Y. Tourian

Ara Y. Tourian

Associate Professor Emeritus of Medicine
Neurology
ara.tourian@duke.edu
Box 3066 Med Ctr, Durham, NC 27710
122 Baker House, Durham, NC 27710

Selected Publications

A case of myelinoclastic diffuse sclerosis in an adult.

Journal Article Neurology · February 1991 We report a case of rapidly progressive cerebral demyelinating disease in a previously healthy 40-year-old woman. This case satisfies the diagnostic criteria for myelinoclastic diffuse sclerosis (MDS), but is unusual in the age of onset. This is the 1st ca ... Full text Link to item Cite

Baclofen in the treatment of post-amputation autonomous stump movements.

Journal Article Eur Neurol · 1987 Baclofen at 20-40 mg/day was used to successfully treat two post-amputation patients who developed continuous complex involuntary movements of the proximal extremity. These autonomous movements were otherwise recalcitrant to therapy and were felt to arise ... Full text Link to item Cite

Fibroblasts in Huntington's disease.

Journal Article Arch Neurol · March 1984 Full text Link to item Cite

L-glutamine D-fructose-6-P aminotransferase regulation by glucose-6-P and UDP-N-acetylglucosamine.

Journal Article Neurochem Res · December 1983 L-Glutamine D-Fructose-6-P aminotransferase regulates hexosamine synthesis. An affinity purified human fibroblast aminotransferase and specific radioisotope assays developed by us were used to show an independent inhibition of the aminotransferase by Gluco ... Full text Link to item Cite

Differential labelling of UDP-N-acetylglucosamine in Huntington's-chorea fibroblasts.

Journal Article Biochem J · May 15, 1981 The hypothesis that there is impaired endogenous synthesis of glucosamine 6-phosphate in Huntington's-chorea fibroblasts was tested by double labelling matched pairs of fibroblasts in culture with carrier-free H3 32PO4 and [U-14C]glucosamine. The [32P]UDP- ... Full text Open Access Link to item Cite

Huntington's-chorea fibroblasts. Cellular protein glycosylation.

Journal Article Biochem J · September 15, 1980 Five cell cultures of Huntington's-chorea fibroblasts exhibit greater than normal protein and lipid glycosylation when labelled with [U-14C]glucosamine. Oligosaccharide--polypeptide chains from all molecular-weight ranges are labelled differentially on sod ... Full text Link to item Cite

Transfer of human chromosomes via human minisegregant cells into mouse cells and the quantitation of the expression of hypoxanthine phosphoribosyltransferase in the hybrids.

Journal Article J Cell Sci · April 1978 The behaviour of human cells arrested in mitosis can be severely perturbed so as to generate numerous small minisegregants containing very few chromosomes. These cells can be separated according to size and DNA content and fused with intact cells. In this ... Full text Open Access Link to item Cite

Membrane abnormalities of Huntington's chorea fibroblasts in culture.

Journal Article Biochem Biophys Res Commun · October 24, 1977 Full text Link to item Cite

The unique identity of rat hepatoma phenylalanine hydroxylase.

Journal Article Biochem Biophys Res Commun · January 12, 1976 Full text Link to item Cite

Control of phenylalanine hydroxylase synthesis in tissue culture by serum and insulin.

Journal Article J Cell Physiol · January 1976 Stationary-phase, minimal deviation hepatoma H4-II-E-C3 cell cultures that are serum-deprived respond with a biphasic time course of phenylalanine hydroxylase induction when dialyzed fetal calf serum or insulin is added. These two agents induce phenylalani ... Full text Link to item Cite

Three Immunologically Distinct Isozymes of Phenylalanine Hydroxylase

Journal Article Biochemistry · September 1, 1975 Three immunologically distinct and non-crossreacting isozymes of rat liver phenylalanine hydroxylase (PH) can be distinguished by immunotitration, immunodiffusion, and immunoabsorption. Only a single isozyme can be distinguished for rat kidney and minimal ... Full text Cite

The effect of serum factors and hormones on phenylalanine hydroxylase synthesis

Journal Article TRANS.AMER.SOC.NEUROCHEM. · January 1, 1974 Cite

Phenylalanine hydroxylase in dilute lethal mice.

Journal Article Biochim Biophys Acta · June 20, 1973 Full text Link to item Cite

Activation of phenylalanine hydroxylase by phenylalanine.

Journal Article Biochim Biophys Acta · August 20, 1971 Full text Link to item Cite