Scholarly Works - Preprints
Preprint
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July 23, 2026
How tissues acquire reproducible shapes to support their function is a fundamental question in developmental biology. Zebrafish semicircular canals form when epithelial pillars partition the lumen of the otic vesicle, the embryonic precursor of the inner e ...
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Preprint
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May 6, 2026
The inner ear constitutes different cell types next to one another: the sensory patches whose hair cells synapse with neurons, the thin channels of three semicircular canals whose perpendicular organization enables detection of directional head rot ...
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Preprint
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May 6, 2026
The inner ear constitutes different cell types next to one another: the sensory patches whose hair cells synapse with neurons, the thin channels of three semicircular canals whose perpendicular organization enables detection of directional head rot ...
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Preprint
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November 14, 2025
Organ morphogenesis uses mechanotransduction feedback loops to convert forces into gene expression changes that regulate cell mechanics. How these loops integrate with developmental programs to ensure robust outcomes remains unclear. We show Yap mechanotra ...
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Preprint
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September 30, 2025
The inner ear constitutes different cell types next to one another: the sensory patches whose hair cells synapse with neurons, the thin channels of three semicircular canals whose perpendicular organization enables detection of directional head rotation, a ...
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Preprint
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2020
Summary How tissues acquire complex shapes is a fundamental question in biology and regenerative medicine. Zebrafish semicircular canals form from invaginations in the otic epithelium (buds) that extend and fuse to form the hubs of each canal. We ...
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