Current Appointments & Affiliations
Assistant Research Professor of Cell Biology
·
2024 - Present
Cell Biology,
Basic Science Departments
Recent Publications
The Nedd4L ubiquitin ligase is activated by FCHO2-generated membrane curvature.
Journal Article The EMBO journal · December 2024 The C2-WW-HECT domain ubiquitin ligase Nedd4L regulates membrane sorting during endocytosis through the ubiquitination of cargo molecules such as the epithelial sodium channel (ENaC). Nedd4L is catalytically autoinhibited by an intramolecular interaction b ... Full text CiteMap7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms in neuronal cells.
Journal Article Life Sci Alliance · August 2022 Microtubule (MT) dynamics are modulated through the coordinated action of various MT-associated proteins (MAPs). However, the regulatory mechanisms underlying MT dynamics remain unclear. We show that the MAP7 family protein Map7D2 stabilizes MTs to control ... Full text Link to item CiteChemico-genetic discovery of astrocytic control of inhibition in vivo.
Journal Article Nature · December 2020 Perisynaptic astrocytic processes are an integral part of central nervous system synapses1,2; however, the molecular mechanisms that govern astrocyte-synapse adhesions and how astrocyte contacts control synapse formation and function are largely unknown. H ... Full text Link to item CiteRecent Grants
Molecular, Synaptic, and Circuit Basis for Schizophrenia-related Phenotypes
ResearchSenior Research Associate · Awarded by National Institutes of Health · 2014 - 2020Fragile X Phenotypes Modulated by Altered Signaling to the Synaptic Cytoskeleton
ResearchSenior Research Associate · Awarded by National Institutes of Health · 2014 - 2018Quantitative Analysis of the Postsynaptic Inhibitory Complex In Vivo
ResearchSenior Research Associate · Awarded by National Institutes of Health · 2015 - 2017View All Grants
Education, Training & Certifications
Kumamoto University (Japan) ·
2003
Ph.D.