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Akiyoshi Uezu

Assistant Research Professor of Cell Biology
Cell Biology
303 Research Drive, 471 Sands, Durham, NC 27710

Current Appointments & Affiliations


Assistant Research Professor of Cell Biology · 2024 - Present Cell Biology, Basic Science Departments

Recent Publications


Identification of New Ciliary Signaling Pathways in the Brain and Insights into Neurological Disorders.

Journal Article J Neurosci · August 13, 2025 Primary cilia are conserved sensory hubs essential for signaling transduction and embryonic development. Ciliary dysfunction causes a variety of developmental syndromes with neurological features and cognitive impairment whose basis mostly remains unknown. ... Full text Link to item Cite

The Nedd4L ubiquitin ligase is activated by FCHO2-generated membrane curvature.

Journal Article EMBO J · December 2024 The C2-WW-HECT domain ubiquitin ligase Nedd4L regulates membrane sorting during endocytosis through the ubiquitination of cargo molecules such as the epithelial sodium channel (ENaC). Nedd4L is catalytically autoinhibited by an intramolecular interaction b ... Full text Link to item Cite

Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms in neuronal cells.

Journal Article Life Sci Alliance · August 2022 Microtubule (MT) dynamics are modulated through the coordinated action of various MT-associated proteins (MAPs). However, the regulatory mechanisms underlying MT dynamics remain unclear. We show that the MAP7 family protein Map7D2 stabilizes MTs to control ... Full text Link to item Cite
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Recent Grants


Molecular, Synaptic, and Circuit Basis for Schizophrenia-related Phenotypes

ResearchSenior Research Associate · Awarded by National Institutes of Health · 2014 - 2020

Fragile X Phenotypes Modulated by Altered Signaling to the Synaptic Cytoskeleton

ResearchSenior Research Associate · Awarded by National Institutes of Health · 2014 - 2018

Quantitative Analysis of the Postsynaptic Inhibitory Complex In Vivo

ResearchSenior Research Associate · Awarded by National Institutes of Health · 2015 - 2017

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Education, Training & Certifications


Kumamoto University (Japan) · 2003 Ph.D.