Overview
Research in statistical genetics and computational biology. Focused on estimation of population structure / relatedness and applications, including GWAS, heritability estimation, and admixture.
Current Duke Appointments & Affiliations
Assistant Professor of Biostatistics & Bioinformatics
·
2018 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Faculty Network Member of the Duke Institute for Brain Sciences
·
2020 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Recent Scholarly Works
Polygenic risk scores and HLA class II variants are biomarkers of corticosteroid response in childhood nephrotic syndrome.
Journal article Kidney Int · June 2026 INTRODUCTION: Nephrotic syndrome (NS), a common glomerular disease in children, is classified based on response to corticosteroid therapy as either steroid-sensitive nephrotic syndrome (SSNS), or steroid-resistant nephrotic syndrome (SRNS). However, there ... Full text Link to item CiteKinship estimation bias carries over to heritability estimation bias using variance components.
Journal article Genetics · February 4, 2026 Heritability is a fundamental parameter of diseases and other traits, quantifying the contribution of genetics to that trait. Kinship matrices are required for heritability estimation with variance components models. However, the most common "standard" kin ... Full text Link to item CitePolygenic Risk Scores and HLA Class II Variants are Biomarkers of Corticosteroid Response in Childhood Nephrotic Syndrome.
Preprint · August 7, 2025 INTRODUCTION: Nephrotic syndrome (NS), a common glomerular disease in children, is classified based on response to corticosteroid therapy as either steroid-sensitive nephrotic syndrome (SSNS), or steroid-resistant nephrotic syndrome (SRNS). However, there ... Full text Link to item CiteRecent Grants
Genetics and Genomics Training Grant
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2026 - 2031Computational Biology and Bioinformatics Training Grant
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2026 - 2031Evolutionary Dynamics of Zoonotic Malaria
ResearchCo Investigator · Awarded by University of California - Los Angeles · 2025 - 2026View All Grants
Education
Princeton University ·
2013
Ph.D.