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Alejandro Ochoa

Assistant Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Integrative Genomics
DUMC 2721, Durham, NC 27710
101 Science Dr, Room 2177C, FCIEMAS, Durham, NC 27705

Overview


Research in statistical genetics and computational biology.  Focused on estimation of population structure / relatedness and applications, including GWAS, heritability estimation, and admixture.

Current Duke Appointments & Affiliations


Assistant Professor of Biostatistics & Bioinformatics · 2026 - Present Biostatistics & Bioinformatics, Division of Integrative Genomics, Biostatistics & Bioinformatics
Faculty Network Member of the Duke Institute for Brain Sciences · 2020 - Present Duke Institute for Brain Sciences, University Institutes and Centers

Recent Scholarly Works


Estimating the correlation of exchangeable variables in assortative mating

Preprint · August 26, 2026 AbstractIn studies of assortative mating, similarity between variables measured in parents is often quantified using correlation. The order of the parents within any given pair can be arbitrary in these app ... Full text Cite

Genetic association meta-analysis is susceptible to confounding by between-study cryptic relatedness.

Journal article HGG Adv · July 27, 2026 Meta-analysis of genome-wide association studies (GWASs) has important advantages, but it assumes that studies are independent, which does not hold when there is relatedness between studies. As a motivating example, recent work suggested applying sex-strat ... Full text Link to item Cite

Polygenic risk scores and HLA class II variants are biomarkers of corticosteroid response in childhood nephrotic syndrome.

Journal article Kidney Int · June 2026 INTRODUCTION: Nephrotic syndrome (NS), a common glomerular disease in children, is classified based on response to corticosteroid therapy as either steroid-sensitive nephrotic syndrome (SSNS), or steroid-resistant nephrotic syndrome (SRNS). However, there ... Full text Link to item Cite
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Recent Grants


Computational Biology and Bioinformatics Training Grant

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2026 - 2031

Genetics and Genomics Training Grant

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2026 - 2031

REGULATORS OF CALCINEURIN PATHWAYS AS DIAGNOSTIC AND THERAPEUTIC TARGETS FOR NEPHROTIC SYNDROME

ResearchInvestigator · Awarded by National Institutes of Health · 2023 - 2026

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Education


Princeton University · 2013 Ph.D.

External Links


Ochoa Lab website