Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., Goethe Universitat Frankfurt Am Main, Faculty of Medicine (Germany) 2011
• Research
• 

  Selected Grants

  • Molecular control of a novel transitional cell state in alveolar regeneration awarded by National Institutes of Health 2020 - 2024
  • Mechanisms of submucosal gland cell mediated airway regeneration awarded by National Institutes of Health 2019 - 2024
  • Human Lung Cell Atlas 1.0 awarded by Northwestern University 2019 - 2020
• 

  External Relationships

  • Justus-Liebig University Giessen
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Moiseenko, Alena, Ana Ivonne Vazquez-Armendariz, Vahid Kheirollahi, Xuran Chu, Aleksandra Tata, Stefano Rivetti, Stefan Günther, et al. “Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration.” Cell Rep 33, no. 12 (December 22, 2020): 108549. https://doi.org/10.1016/j.celrep.2020.108549.
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    • Katsura, Hiroaki, Vishwaraj Sontake, Aleksandra Tata, Yoshihiko Kobayashi, Caitlin E. Edwards, Brook E. Heaton, Arvind Konkimalla, et al. “Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.” Cell Stem Cell 27, no. 6 (December 3, 2020): 890-904.e8. https://doi.org/10.1016/j.stem.2020.10.005.
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    • Kobayashi, Yoshihiko, Aleksandra Tata, Arvind Konkimalla, Hiroaki Katsura, Rebecca F. Lee, Jianhong Ou, Nicholas E. Banovich, Jonathan A. Kropski, and Purushothama Rao Tata. “Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis.” Nat Cell Biol 22, no. 8 (August 2020): 934–46. https://doi.org/10.1038/s41556-020-0542-8.
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    • Tata, Aleksandra, Yoshihiko Kobayashi, Ryan D. Chow, Jasmine Tran, Avani Desai, Abdull J. Massri, Timothy J. McCord, Michael Dee Gunn, and Purushothama Rao Tata. “Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury.” Cell Stem Cell 22, no. 5 (May 3, 2018): 668-683.e6. https://doi.org/10.1016/j.stem.2018.03.018.
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    • Tata, Purushothama Rao, Ryan D. Chow, Srinivas Vinod Saladi, Aleksandra Tata, Arvind Konkimalla, Anne Bara, Daniel Montoro, et al. “Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.” Dev Cell 44, no. 6 (March 26, 2018): 679-693.e5. https://doi.org/10.1016/j.devcel.2018.02.024.
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    • Andreone, Benjamin J., Brian Wai Chow, Aleksandra Tata, Baptiste Lacoste, Ayal Ben-Zvi, Kevin Bullock, Amy A. Deik, David D. Ginty, Clary B. Clish, and Chenghua Gu. “Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis.” Neuron 94, no. 3 (May 3, 2017): 581-594.e5. https://doi.org/10.1016/j.neuron.2017.03.043.
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    • Kur, Esther, Jiha Kim, Aleksandra Tata, Cesar H. Comin, Kyle I. Harrington, Luciano da F. Costa, Katie Bentley, and Chenghua Gu. “Temporal modulation of collective cell behavior controls vascular network topology.” Elife 5 (February 24, 2016). https://doi.org/10.7554/eLife.13212.
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    • Gelfand, Maria V., Nellwyn Hagan, Aleksandra Tata, Won-Jong Oh, Baptiste Lacoste, Kyu-Tae Kang, Justyna Kopycinska, Joyce Bischoff, Jia-Huai Wang, and Chenghua Gu. “Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding.” Elife 3 (September 22, 2014): e03720. https://doi.org/10.7554/eLife.03720.
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    • Tata, Aleksandra, David C. Stoppel, Shangyu Hong, Ayal Ben-Zvi, Tiao Xie, and Chenghua Gu. “An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling.” J Cell Biol 205, no. 4 (May 26, 2014): 573–90. https://doi.org/10.1083/jcb.201309004.
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    • Cizelsky, Wiebke, Aleksandra Tata, Michael Kühl, and Susanne J. Kühl. “The Wnt/JNK signaling target gene alcam is required for embryonic kidney development.” Development 141, no. 10 (May 2014): 2064–74. https://doi.org/10.1242/dev.107938.
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    • Murugan, Subramanian, Jingdong Shan, Susanne J. Kühl, Aleksandra Tata, Ilkka Pietilä, Michael Kühl, and Seppo J. Vainio. “WT1 and Sox11 regulate synergistically the promoter of the Wnt4 gene that encodes a critical signal for nephrogenesis.” Exp Cell Res 318, no. 10 (June 10, 2012): 1134–45. https://doi.org/10.1016/j.yexcr.2012.03.008.
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