Current Appointments & Affiliations
Assistant Professor in Medicine
·
2021 - Present
Medicine, Cardiology,
Medicine
Recent Publications
A positive allosteric modulator of the β1AR with antagonist activity for catecholaminergic polymorphic ventricular tachycardia.
Journal Article J Clin Invest · October 16, 2025 Orthosteric β-blockers represent the leading pharmacological intervention for managing heart diseases owing to their ability to competitively antagonize β-adrenergic receptors (βARs). However, their use is often limited by the development of adverse effect ... Full text Link to item CiteMechanism of beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy.
Preprint · September 27, 2025 Full text Link to item CiteSmall-molecule modulation of β-arrestins.
Preprint · April 8, 2025 Full text Link to item CiteRecent Grants
The GPCR Collaborative: Revealing the molecular determinants and fidelity of GPCR signaling in health and disease
ResearchAssistant Research Professor · Awarded by St. Jude Children's Research Hospital · 2023 - 2028Mechanisms of Maladaptation in Heart Failure
ResearchCo Investigator · Awarded by National Heart, Lung, and Blood Institute · 1996 - 2027Molecular Regulation of Cardiovascular 7 TM Receptors
ResearchCo Investigator · Awarded by National Heart, Lung, and Blood Institute · 1976 - 2027View All Grants
Education, Training & Certifications
University of Connecticut ·
2008
Ph.D.