Current Appointments & Affiliations
Assistant Professor in Medicine
·
2021 - Present
Medicine, Cardiology,
Medicine
Recent Publications
Small Molecule Modulators of β-arrestins.
Preprint · December 27, 2024 Full text Link to item CiteBeta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy.
Preprint · August 6, 2024 Full text Link to item CiteRole of the V2R-βarrestin-Gβγ complex in promoting G protein translocation to endosomes.
Journal Article Commun Biol · July 7, 2024 Classically, G protein-coupled receptors (GPCRs) promote signaling at the plasma membrane through activation of heterotrimeric Gαβγ proteins, followed by the recruitment of GPCR kinases and βarrestin (βarr) to initiate receptor desensitization and internal ... Full text Link to item CiteRecent Grants
The GPCR Collaborative: Revealing the molecular determinants and fidelity of GPCR signaling in health and disease
ResearchAssistant Research Professor · Awarded by St. Jude Children's Research Hospital · 2023 - 2028Mechanisms of Maladaptation in Heart Failure
ResearchCo Investigator · Awarded by National Heart, Lung, and Blood Institute · 1996 - 2027Molecular Regulation of Cardiovascular 7 TM Receptors
ResearchCo Investigator · Awarded by National Heart, Lung, and Blood Institute · 1976 - 2027View All Grants
Education, Training & Certifications
University of Connecticut ·
2008
Ph.D.