Alexander Tan Limkakeng Jr.

Professor of Emergency Medicine

Emergency Medicine

2301 Erwin Road Box 3096, Durham, NC 27710

ORCID iD

https://orcid.org/0000-0002-9822-5595

2301 Erwin Road, Box 3096, Durham, NC 27710

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Academic Experience
1. Current Duke Appointments & Affiliations
2. Previous Duke Appointments & Affiliations

Global Scholarship

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Research

Scholarly Works

Teaching & Mentoring
1. Teaching Summary

Recognition
1. Academic Honors
2. News Items

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Scholarly Works - Conferences

Proof-of-Principle: CRISPR-Based Rapid, Amplification-Free Bacterial RNA Detection for POC Bacteremia Detection

Conference ANNALS OF EMERGENCY MEDICINE · October 2024 Link to item Cite

Qualitative Analysis Of Study Participant Feedback On Emergency Department Acupuncture To Improve Trial Participation Experience

Conference JOURNAL OF PAIN · April 2023 Link to item Cite

Assessment of deep learning-based triage for robotically acquired retinal optical coherence tomography (OCT) images in an emergency department population

Conference Investigative Ophthalmology and Visual Science · June 1, 2022 Link to item Cite

COVID-19 Infection Experiences and Social Determinants of Health in North Carolina: A Qualitative Analysis

Conference ANNALS OF EMERGENCY MEDICINE · August 2021 Link to item Cite

Social Determinants of Health and COVID-19 Infection in North Carolina: A Geospatial Analysis

Conference ANNALS OF EMERGENCY MEDICINE · August 2021 Link to item Cite

Remote retinal imaging of patients from the ER using robotically aligned OCT

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · June 2021 Link to item Cite

RISK ASSESSMENT OF EMERGENCY DEPARTMENT PATIENTS WITH HIGH SENSITIVITY CARDIAC TROPONIN I CONCENTRATIONS BELOW THE 99TH PERCENTILE SEX-SPECIFIC UPPER REFERENCE LIMITS

Conference JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY · May 11, 2021 Link to item Cite

3 Non-specific ECG Findings in Patients with Low High-Sensitivity Troponin Values Are Not Associated With Significant 30-day Adverse Outcomes

Conference Annals of Emergency Medicine · October 2020 Featured Publication Full text Cite

302 Biomarker Profiling for Obstructive Coronary Artery Disease: A PROMISE Substudy

Conference Annals of Emergency Medicine · October 2020 Featured Publication Full text Cite

Dispositions for Patients Ruled Out for Acute Myocardial Infarction Using a 1-Hour High Sensitivity Troponin I Algorithm: Home or Hospital?

Conference ANNALS OF EMERGENCY MEDICINE · October 2020 Link to item Cite

Cardiac Testing of Patients Ruled Out for Acute Myocardial Infarction Using a Rapid High Sensitivity Troponin I Algorithm, but Not Discharged

Conference ANNALS OF EMERGENCY MEDICINE · October 2020 Link to item Cite

Performance of Novel High-Sensitivity Cardiac Troponin I Assays for 0/1-Hour and 0/2- to 3-Hour Evaluations for Acute Myocardial Infarction: Results From the HIGH-US Study.

Conference Ann Emerg Med · July 2020 Featured Publication STUDY OBJECTIVE: We determine the accuracy of high-sensitivity cardiac troponin I (hs-cTnI), European-derived, rapid, acute myocardial infarction, rule-out/rule-in algorithms applied to a US emergency department (ED) population. METHODS: Adults presenting ... Full text Open Access Link to item Cite

ASSOCIATION OF A CYTOKINE RESPONSE NETWORK WITH FUNCTIONAL RECOVERY FROM SNAKEBITE ENVENOMING

Conference TOXICON · July 2020 Link to item Cite

Detection of Retinal Detachment by ED Clinicians on OCT Images versus Fundus Photos

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · June 2020 Link to item Cite

HIGH SENSITIVITY TROPONIN VALUES RAPIDLY RULE-OUT MYOCARDIAL INFARCTION AND ALLOW FOR ED DISCHARGE IN A HIGHER RISK PATIENT POPULATION COMPARED TO CONTEMPORARY PRACTICE

Conference JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY · March 24, 2020 Link to item Cite

Serum Procalcitonin Trends in Hospital-Acquired Infections: A Prospective Multi-Center Observational Cohort

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2020 Link to item Cite

The Prevalence of Acute Myocardial Infarction Among Emergency Department Patients in Northern Tanzania

Conference CIRCULATION · November 19, 2019 Link to item Cite

31 Impacting Emergency Department Left Without Being Seen Rates Through Physician Resourcing

Conference Annals of Emergency Medicine · October 2019 Full text Cite

217 A Method for Stratifying Emergency Department Visits by Severity and Complexity: National Hospital Ambulatory Medical Care Survey Items

Conference Annals of Emergency Medicine · October 2019 Full text Cite

99EMF Pilot of Integrated Metabolomic and MicroRNA Analysis to Identify Myocardial Ischemia on Emergency Department Cardiac Stress Tests

Conference Annals of Emergency Medicine · October 2019 Featured Publication Full text Cite

129 United States Emergency Department Use of Medications with Pharmacogenetic Recommendations

Conference Annals of Emergency Medicine · October 2019 Full text Cite

59 Effect of High Sensitivity Troponin Implementation on Emergency Department Observation Unit Operations

Conference Annals of Emergency Medicine · October 2019 Full text Cite

5 Adverse Outcomes 30 Days After Emergency Department Evaluation for Myocardial Infarction Determined Solely by High Sensitivity Troponin I Values for a 1-Hour Rule-Out/Rule-In Acute Myocardial Infarction Algorithm

Conference Annals of Emergency Medicine · October 2019 Full text Cite

99 A Comparison of Direct Versus Video Laryngoscopy for Difficult Airway Patients in the Emergency Department: A National Emergency Airway Registry Study

Conference Annals of Emergency Medicine · October 2018 Full text Cite

136 Utilization of Bougie Adjunct Devices in the Emergency Department: A National Emergency Airway Registry Study

Conference Annals of Emergency Medicine · October 2018 Full text Cite

67EMF Comparison of Dyspnea Measurement Instruments in Acute Heart Failure: Results From the DYSPNEA-AHF Study

Conference Annals of Emergency Medicine · October 2018 Full text Cite

212 3D Volume Ultrasound of the Right Lower Quadrant for Diagnosis of Appendicitis

Conference Annals of Emergency Medicine · October 2018 Full text Cite

32EMF Isolating Micro-Ribonucleic Acids from Peripheral Plasma to Identify Myocardial Ischemia During Stress Testing in Emergency Department Patients

Conference Annals of Emergency Medicine · October 2018 Featured Publication Full text Cite

Evaluation of Transplant Kidneys Using a Novel Point of Care 3D Ultrasound System.

Conference AMERICAN JOURNAL OF TRANSPLANTATION · June 1, 2018 Link to item Cite

OVERALL AND SEX-SPECIFIC REFERENCE RANGES FOR HIGH-SENSITIVITY TROPONIN T GEN 5 STAT IN THE UNITED STATES

Conference Journal of the American College of Cardiology · March 2018 Full text Cite

313 Evaluation of Phenylalanine and Tyrosine Concentrations in Traumatically Injured Patients

Conference Annals of Emergency Medicine · October 2017 Full text Cite

105 Unexpected Cardiac Magnetic Resonance Imaging Findings in Patients Presenting to the Emergency Department for Potential Acute Coronary Syndrome

Conference Annals of Emergency Medicine · October 2017 Full text Cite

1 Chest Pain Care Patterns Across the Carolinas: Determining the Readiness for Widespread HEART Pathway Dissemination

Conference Annals of Emergency Medicine · October 2017 Full text Cite

197 Geographic Distribution of Diagnostic Testing for Acute Coronary Syndrome in Brazil

Conference Annals of Emergency Medicine · October 2017 Full text Cite

11 High-Sensitivity Troponin T Identifies Patients at Very Low Risk of Adverse Events

Conference Annals of Emergency Medicine · October 2017 Full text Cite

73 Clinical Suspicion and D-Dimer Levels in Venous Thromboembolism Patients With Low and High Clot Burden

Conference Annals of Emergency Medicine · October 2017 Full text Cite

Analyzing the Components of the Wells' Score for Pulmonary Embolus Can Strengthen Unstructured Physician Gestalt

Conference ANNALS OF EMERGENCY MEDICINE · October 1, 2017 Link to item Cite

Physician Gestalt is the Most Predictive Component of the Wells' Deep Venous Thrombosis Score in Diagnosing Subsequent Deep Venous Thrombosis

Conference ANNALS OF EMERGENCY MEDICINE · October 1, 2017 Link to item Cite

12 Highly Elevated Quantitative D-Dimer Assay Values Increase the Likelihood of Venous Thromboembolism

Conference Annals of Emergency Medicine · October 2017 Full text Cite

Toll-Like Receptor Signaling as a Prognostic Tool in Trauma Patients

Conference Journal of the American College of Surgeons · October 2016 Full text Cite

Copeptin to rule out myocardial infarction in blacks versus Caucasians

Conference EUROPEAN HEART JOURNAL · August 1, 2016 Link to item Cite

BIOMARKER MODEL FOR CORONARY ARTERY DISEASE

Conference Journal of the American College of Cardiology · April 2016 Full text Cite

HOSPITALIZATION OF LOW RISK CHEST PAIN PATIENTS WITH NORMAL TROPONIN AND COPEPTIN

Conference Journal of the American College of Cardiology · April 2016 Full text Cite

Does Copeptin Provide Additional Risk Stratification in Chest Pain Patients With a Mild Troponin Elevation?

Conference CIRCULATION · November 25, 2014 Link to item Cite

Cardiac Troponin Levels Do Not Change in Response to Exercise Stress Testing

Conference CIRCULATION · November 25, 2014 Link to item Cite

MID-REGIONAL PROADRENOMEDULLIN PREDICTS LONG-TERM MORTALITY IN PATIENTS WITH CHEST PAIN

Conference Journal of the American College of Cardiology · April 2014 Full text Cite

CAN A SECOND MEASUREMENT OF COPEPTIN IMPROVE ACUTE MYOCARDIAL INFARCTION RULE OUT?

Conference Journal of the American College of Cardiology · April 2014 Full text Cite

COPEPTIN PROVIDES PROGNOSTIC VALUE IN PATIENTS WITH ACUTE CHEST PAIN

Conference Journal of the American College of Cardiology · April 2014 Full text Cite

The Protocol Acuity Scoring Tool for Prediction of Emergency Medicine Research Study Workload

Conference ANNALS OF EMERGENCY MEDICINE · October 1, 2013 Link to item Cite

244 Analysis of Morbidity and Mortality of Patients Admitted From the Emergency Department for Pneumonia But Treated for Alternate Diagnoses

Conference Annals of Emergency Medicine · October 2011 Full text Cite

38 Exercise Treadmill Is an Appropriate Risk Stratification Tool in Low Risk Chest Pain Patients

Conference Annals of Emergency Medicine · October 2011 Full text Cite

41: Utility of Cardiac Stress Testing In Young Patients In an Observation Unit

Conference Annals of Emergency Medicine · September 2010 Full text Cite

177: A Comparative Analysis of Screening Hypertensive Patients for Left Ventricular Abnormality With Electrocardiograph and NT-proBNP

Conference Annals of Emergency Medicine · September 2009 Full text Cite

422: A Comparison of Rates of Emergency Department and Observation Unit Adverse Drug Events

Conference Annals of Emergency Medicine · September 2009 Full text Cite

380: Blatchford Clinical Risk Stratification Score May Be Used in an Observation Unit Setting to Risk Stratify Patients With Gastrointestinal Bleeding

Conference Annals of Emergency Medicine · September 2009 Full text Cite

238: An Analysis of Emergency Department Observation Units Impact on Patient Satisfaction Scores

Conference Annals of Emergency Medicine · September 2009 Full text Cite

161: Do Prolonged Emergency Department Waiting Times Reduce Emergency Research Consent Rates?

Conference Annals of Emergency Medicine · September 2009 Full text Cite

165: Delays and High Costs Associated With Emergency Physician Variation in Diagnostic Approaches to Venous Thromboembolism

Conference Annals of Emergency Medicine · October 2008 Full text Cite

303: Incidence and Impact of Renal Dysfunction on Acute Coronary Syndrome in Chest Pain Observation Unit Patients

Conference Annals of Emergency Medicine · October 2008 Full text Cite

150: Blood Pressure Response in Hypertensive Emergency Department Patients With a History of End Organ Disease

Conference Annals of Emergency Medicine · October 2008 Full text Cite

Patients' pain and estimate of their risk for cardiac disease do not predict preferences for cardiac tests and procedures

Conference ANNALS OF EMERGENCY MEDICINE · October 1, 2006 Link to item Cite

Effects of implementing a modified electronic medical record and comprehensive patient tracking system on the patient care activities of emergency department staff

Conference Annals of Emergency Medicine · October 2004 Full text Cite

Impact of institution of an electronic hospital information system on nursing quick registration and triage times

Conference Annals of Emergency Medicine · October 2004 Full text Cite