Scholars@Duke

• Research
• 

  Selected Grants

  • Mechanisms of sex-biased maternal high-fat diet-induced brain changes: a role for inflammation and placental serotonin awarded by National Institutes of Health 2021 - 2024
  • Environmental Toxins and Microglia-Synapse Interactions in Autism awarded by National Institutes of Health 2016 - 2021
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Ceasrine, Alexis M., Benjamin A. Devlin, Jessica L. Bolton, Lauren A. Green, Young Chan Jo, Carolyn Huynh, Bailey Patrick, et al. “Maternal diet disrupts the placenta-brain axis in a sex-specific manner.” Nat Metab 4, no. 12 (December 2022): 1732–45. https://doi.org/10.1038/s42255-022-00693-8.
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    • Ceasrine, Alexis M., Lauren A. Green, and Staci D. Bilbo. “Protocol to measure endotoxin from opaque tissues in mice using an optimized kinetic limulus amebocyte lysate assay.” Star Protocols 3, no. 4 (December 2022): 101669. https://doi.org/10.1016/j.xpro.2022.101669.
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    • Block, Carina L., Oznur Eroglu, Stephen D. Mague, Caroline J. Smith, Alexis M. Ceasrine, Chaichontat Sriworarat, Cameron Blount, et al. “Prenatal environmental stressors impair postnatal microglia function and adult behavior in males.” Cell Rep 40, no. 5 (August 2, 2022): 111161. https://doi.org/10.1016/j.celrep.2022.111161.
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    • Ceasrine, Alexis M., and Staci D. Bilbo. “Dietary fat: a potent microglial influencer.” Trends in Endocrinology and Metabolism: Tem 33, no. 3 (March 2022): 196–205. https://doi.org/10.1016/j.tem.2021.12.005.
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    • Ceasrine, Alexis M., Benjamin A. Devlin, Jessica L. Bolton, Lauren A. Green, Young Chan Jo, Carolyn Huynh, Bailey Patrick, et al. “Maternal diet disrupts the placenta-brain axis in a sex-specific manner,” November 13, 2021. https://doi.org/10.1101/2021.11.12.468408.
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    • Ceasrine, Alexis M., and Staci D. Bilbo. “Primetime for microglia: When stress and infection collide.” Neuron 109, no. 16 (August 2021): 2503–5. https://doi.org/10.1016/j.neuron.2021.07.023.
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    • Bordt, Evan A., Alexis M. Ceasrine, and Staci D. Bilbo. “Microglia and sexual differentiation of the developing brain: A focus on ontogeny and intrinsic factors.” Glia 68, no. 6 (June 2020): 1085–99. https://doi.org/10.1002/glia.23753.
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    • Ceasrine, Alexis M., Nelmari Ruiz-Otero, Eugene E. Lin, David N. Lumelsky, Erica D. Boehm, and Rejji Kuruvilla. “Tamoxifen Improves Glucose Tolerance in a Delivery-, Sex-, and Strain-Dependent Manner in Mice.” Endocrinology 160, no. 4 (April 2019): 782–90. https://doi.org/10.1210/en.2018-00985.
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    • Ceasrine, Alexis M., Eugene E. Lin, David N. Lumelsky, Radhika Iyer, and Rejji Kuruvilla. “Adrb2 controls glucose homeostasis by developmental regulation of pancreatic islet vasculature.” Elife 7 (October 2018): e39689. https://doi.org/10.7554/elife.39689.
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    • Leung, Wilson, Christopher D. Shaffer, Elizabeth J. Chen, Thomas J. Quisenberry, Kevin Ko, John M. Braverman, Thomas C. Giarla, et al. “Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element.” G3 (Bethesda) 7, no. 8 (August 7, 2017): 2439–60. https://doi.org/10.1534/g3.117.040907.
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    • Houtz, Jessica, Philip Borden, Alexis Ceasrine, Liliana Minichiello, and Rejji Kuruvilla. “Neurotrophin Signaling Is Required for Glucose-Induced Insulin Secretion.” Developmental Cell 39, no. 3 (November 2016): 329–45. https://doi.org/10.1016/j.devcel.2016.10.003.
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    • Wang, Guangliang, Surendra K. Rajpurohit, Fabien Delaspre, Steven L. Walker, David T. White, Alexis Ceasrine, Rejji Kuruvilla, et al. “First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass.” Elife 4 (July 2015). https://doi.org/10.7554/elife.08261.
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    • Otis, Jessica P., Erin M. Zeituni, James H. Thierer, Jennifer L. Anderson, Alexandria C. Brown, Erica D. Boehm, Derek M. Cerchione, et al. “Zebrafish as a model for apolipoprotein biology: comprehensive expression analysis and a role for ApoA-IV in regulating food intake.” Disease Models & Mechanisms 8, no. 3 (March 2015): 295–309. https://doi.org/10.1242/dmm.018754.
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