Overview
I am a surgeon with interest in immune management of transplant recipients. I am particularly interested in therapies that influence T cell costimulation pathways and adjuvant therapies that facilitate costimulation blockade to prevent the rejection of transplanted organs without undue suppression of protective immunity. I am also interested in understanding how injury, such as that occurring during trauma or in elective surgery, influences immune responses and subsequent healing following injury.
Current Duke Appointments & Affiliations
David C. Sabiston, Jr. Distinguished Professor of Surgery
·
2015 - Present
Surgery, Abdominal Transplant Surgery,
Surgery
Professor of Surgery
·
2014 - Present
Surgery, Abdominal Transplant Surgery,
Surgery
Professor in Pediatrics
·
2014 - Present
Pediatrics,
Clinical Science Departments
Professor in Integrative Immunobiology
·
2014 - Present
Integrative Immunobiology,
Basic Science Departments
Member of the Duke Cancer Institute
·
2015 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Scholarly Works
Self-Reported Flourishing Among U.S. Surgeons: A National Physician Survey.
Journal article J Am Coll Surg · June 4, 2026 BACKGROUND: While surgeon burnout is extensively documented, the medical community has limited corresponding data regarding what it might mean to thrive in the profession as captured by robust measures of "flourishing." STUDY DESIGN: We conducted a cross-s ... Full text Link to item CiteSurgical Case Sequencing and Patient Flow: A Simulation Study With Downstream Resources.
Journal article J Surg Res · May 2026 INTRODUCTION: Surgical sequencing impacts patient flow and hospital operations. Discrete event simulation has been used to study these effects, specifically examining heuristics such as shortest cases first (SCF) and longest cases first (LCF). We propose a ... Full text Link to item CiteAmerican Journal of Transplantation at 25 years: A trusted voice.
Journal article Am J Transplant · May 2026 Full text Link to item CiteRecent Grants
VEL-101 in kidney transplant (RENGEVITY-201) - Pro00119645
Clinical TrialPrincipal Investigator · Awarded by Veloxis Pharmaceuticals · 2026 - 2036Stimulating Access to Research in Residency (StARR) - NIAID
Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of Allergy and Infectious Diseases · 2018 - 2029Advanced Immunobiology Traning Program for Surgeons
Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2019 - 2029View All Grants
Education
Duke University ·
1992
Ph.D.
Duke University, School of Medicine ·
1987
M.D.
Old Dominion University ·
1983
B.S.