Allan Douglas Kirk | Scholars@Duke

Allan Douglas Kirk
David C. Sabiston, Jr. Distinguished Professor of Surgery

I am a surgeon with interest in immune management of transplant recipients. I am particularly interested in therapies that influence T cell costimulation pathways and adjuvant therapies that facilitate costimulation blockade to prevent the rejection of transplanted organs without undue suppression of protective immunity. I am also interested in understanding how injury, such as that occurring during trauma or in elective surgery, influences immune responses and subsequent healing following injury.

Current Appointments & Affiliations

David C. Sabiston, Jr. Distinguished Professor of Surgery, Surgery, Abdominal Transplant Surgery, Surgery 2015
Professor of Surgery, Surgery, Abdominal Transplant Surgery, Surgery 2014
Chair of Surgery, Surgery, Clinical Science Departments 2014
Professor in Pediatrics, Pediatrics, Clinical Science Departments 2014
Professor in Integrative Immunobiology, Integrative Immunobiology, Basic Science Departments 2014
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2015
Core Faculty in Innovation & Entrepreneurship, Duke Innovation & Entrepreneurship, Initiatives 2021

Contact Information

3704, Durham, NC 27710
allan.kirk@duke.edu

Background
Education, Training, & Certifications
- Fellow, Multi Organ Transplantation, University of Wisconsin - Madison 1995 - 1997
- Chief Resident, Surgery, Duke University 1994 - 1995
- Senior Resident, Surgery, Duke University 1992 - 1994
- Research Fellow, Surgery, Duke University 1989 - 1992
- Ph.D., Duke University 1992
- Intern & Junior Resident, Surgery, Duke University 1987 - 1989
- M.D., Duke University School of Medicine 1987
- B.S., Old Dominion University 1983
Previous Appointments & Affiliations
- Instructor, Temporary in the Department of Surgery, Surgery, Abdominal Transplant Surgery, Surgery 2014
Leadership & Clinical Positions at Duke
- Chair, Department of Surgery
  Professor of Surgery, Immunology and Pediatrics
  
  Surgeon-in-Chief, Duke University Health System
Academic Positions Outside Duke
- Editor-in-Chief, American Journal of Transplantation. 2010 - 2020
Recognition
In the News
- MAY 20, 2020 School of Medicine
  
  What Causes a Person's Immune System to Weaken?
- JUN 9, 2016 KVUE-Austin, WFMY-Greensboro
  
  N.C.'s first hand transplant goes to man from Texas
- JUN 9, 2016 The News & Observer
  
  Texas man receives N.C.’s first hand transplant at Duke
- DEC 3, 2015
  
  Duke Surgery Helping Wounded Warriors
- MAY 1, 2015
  
  Duke Announces 2015 Distinguished Professors
Awards & Honors
- Member. National Academy of Medicine. 2016
Research
Selected Grants
- Targeting the B Cell Response to Treat Antibody-Mediated Rejection awarded by National Institutes of Health 2021 - 2028
- Clinical and Mechanistic Factors Impacting Transplant Outcomes (U01) awarded by National Institutes of Health 2022 - 2027
- Genetic engineering of kidney allografts by ex vivo perfusion delivery of adeno-associated viral vectors awarded by National Institutes of Health 2022 - 2027
- Neonatal porcine islet xenografts for the treatment of type 1 diabetes awarded by National Institutes of Health 2014 - 2025
- Basic Immunology Training Program awarded by National Institutes of Health 2022 - 2025
- Genetic approaches to skin regeneration in zebrafish awarded by National Institutes of Health 2020 - 2025
- Viela Bio Inc., VIB4920 Drug Study for Kidney Transplant Patients awarded by Viela Bio, Inc. 2019 - 2024
- Advanced Immunobiology Traning Program for Surgeons awarded by National Institutes of Health 2019 - 2024
- Unified Program for Therapeutics in Children awarded by National Institutes of Health 2019 - 2024
- (TEACH) Immune Tolerance Network awarded by Benaroya Research Institute at Virginia Mason 2018 - 2024
- ITN Study: EP234: Real time flow cytometry at Duke for TEACH awarded by Benaroya Research Institute at Virginia Mason 2018 - 2024
- TEACH Clinical Trial awarded by Benaroya Research Institute at Virginia Mason 2018 - 2024
- Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTG) awarded by National Institutes of Health 2018 - 2023
- Duke Resident Physician-Scientist Program - NIAID awarded by National Institutes of Health 2018 - 2023
- Advancing Transplantation Outcomes in Children - Mechnistic awarded by Boston Children's Hospital 2021 - 2023
- Applying precision MEdicine to optimize desensitization with noveL bIOlogics or cellular theRApies in highly sensiTized kidney transplant patiEnts (AMELIORATE) awarded by University of California - San Francisco 2019 - 2023
- Surgical Critical Care Initiative (SC2I): Civilian application of military decision support tools for critically injured patients. awarded by Henry M. Jackson Foundation 2021 - 2023
- AX-158: Utilizing Nck Inhibition as Immunomodulation in Allotransplantation awarded by Artax Biopharma, Inc. 2021 - 2023
- ITN056ST Optimal Co-Chair Protocol awarded by Benaroya Research Institute at Virginia Mason 2014 - 2023
- Determining Proliferative Potential and Factors Necessary for the Proliferation awarded by American Society of Transplant Surgeons 2020 - 2021
- Examining the Depletional Profile of the Anti-CD2 awarded by American Society of Transplant Surgeons 2020 - 2021
- Immunomodulation to Optimize Vascularized Composite Allograft Integration for Limb Loss Therapy awarded by Department of Defense 2015 - 2021
- Sc2i awarded by Henry M. Jackson Foundation 2020 - 2021
- The Lung Transplant Clinical Trials Network (LT-CTN) awarded by National Institutes of Health 2014 - 2021
- Nonhuman Primate Reagent Resources awarded by University of Massachusetts Medical School 2019 - 2021
- Mechanisms of Belatacept-resistant Renal Allograft Rejection awarded by Bristol-Myers Squibb Company 2020 - 2021
- Donor apoptotic cell infusion for tolerance to monkey kidney allografts awarded by The Board of Regents of the University of Wisconsin System 2019 - 2021
- Immune Tolerance Network - Flow Cytometry awarded by Benaroya Research Institute at Virginia Mason 2014 - 2021
- American Journal of Transplantation awarded by American Society of Transplantation 2016 - 2020
- Interface of Mitochondrial Quality Control and Immune Activation in Heart Transplant awarded by Foundation for Anesthesia Education and Research 2018 - 2020
- Positioning Vascilarized Composite Allotramsplantation within the Spectrum of Transplantation awarded by Department of Defense 2014 - 2020
- Phase 2 Study of Belatacept, Alemtuzumab, and Sirolimus in Renal Transplantation awarded by Food and Drug Administration 2015 - 2020
- Establishing a Linear Program for the Development of Co-stimulation Resistant T-cells awarded by American Society of Transplant Surgeons 2019 - 2020
- T cell Receptor Diversity as a Determinant of Co-stimulation Blockade Resistance awarded by American Society of Transplant Surgeons 2019 - 2020
- SC2i awarded by Henry M. Jackson Foundation 2014 - 2020
- ITN iWITH Project awarded by Benaroya Research Institute at Virginia Mason 2018 - 2020
- Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients awarded by University of California - San Francisco 2014 - 2019
- CD57+CD4+ T cells in Belatacept-resistant Renal Allograft Rejection awarded by Bristol-Myers Squibb Company 2016 - 2019
- EP86: Flow Cytometry for Liver Transplant Tolerance Enhanced by Sirolimus Therapy awarded by Benaroya Research Institute at Virginia Mason 2018 - 2019
- The impact of Epstein Barr virus infection on the immune response in pediatric transplant recipients awarded by Stanford University 2018 - 2019
- (TEACH) Atemtuzumab, Costimulation Blockade and Sirolimus: A Tolerogenic Canvas for Donor Antigen Delivery via Mesenchymal awarded by Benaroya Research Institute at Virginia Mason 2014 - 2018
- Role of Mitochondrial Injury in the Pathogenesis of Primary Graft Dysfunction Following Cardiac Transplantation awarded by National Institutes of Health 2016 - 2018
- T Cell Maturation and the Nexus of Viral- and Allo-Immunity awarded by National Institutes of Health 2014 - 2017
- Transplant Tolerance in Non-Human Primates awarded by Emory University 2014 - 2017
- Mouse Heart Transplant awarded by Quadriga BioSciences, Inc. 2017
- The Role of Rapamycin in Altering Graft Endothelial Cell Alloimmunogenicity awarded by American Society of Transplant Surgeons 2016 - 2017
- Role of Mitochondrial Injury in the Pathogenesis of Primary Graft Dysfunction Following Cardiac Transplantation awarded by American Society of Transplantation 2016 - 2017
- Exercise, Nitric Oxide Bioavailability and Arteriovenous Fistula Maturation awarded by National Institutes of Health 2014 - 2017
- Immune Tolerance Network - Flow Cytometry awarded by Benaroya Research Institute at Virginia Mason 2016 - 2017
- ASTS-Alexion Presidential Student Mentor Grant awarded by American Society of Transplant Surgeons 2015 - 2016
- Development of a Composite Tissue Allotransplantation Research Program awarded by Emory University 2014 - 2016
- CD57+CD4+ T cells in Belatacept-resistant Renal Allograft Rejection awarded by Bristol-Myers Squibb Company 2014 - 2015
- Transplant Tolerance in Non-Human Primates awarded by Emory University 2014
External Relationships
- AskBio
- Bristol-Myers Squibb
- CareDx
- Clinetic (formerly MedBlue Data)
- Innoskel
- MedBlue Incubator
- Novartis pharmaceuticals
- PeriOptions
- Sana Biotechnology Inc.
- Sanofi Genzyme
- Surgical Safety Technologies
- Talaris
- Veloxis
- Vertex Pharmaceuticals Inc.
- egenesis
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Adams, Andrew, Linda C. Cendales, David K. C. Cooper, Emanuele Cozzi, John Gill, Eric Judd, Eliezer Katz, et al. “Asts-Ast Report Of Fda Meeting On Regulatory Expectations For Xenotransplantation Products.” Am J Transplant, May 20, 2023. https://doi.org/10.1016/j.ajt.2023.05.010.
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  - Moris, Dimitrios, Richard Barfield, Cliburn Chan, Scott Chasse, Linda Stempora, Jichun Xie, Jennifer K. Plichta, et al. “Immune Phenotype and Postoperative Complications following Elective Surgery.” Ann Surg, April 13, 2023. https://doi.org/10.1097/SLA.0000000000005864.
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  - Li, Shu, Imran J. Anwar, Aidan J. Canning, Tuan Vo-Dinh, Allan D. Kirk, and He Xu. “Xenorecognition and costimulation of porcine endothelium-derived extracellular vesicles in initiating human porcine-specific T cell immune responses.” Am J Transplant, April 11, 2023. https://doi.org/10.1016/j.ajt.2023.04.006.
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  - Knatterud, Mary E., Richard L. Simmons, William Payne, Peter Stock, Blanche Chavers, Nancy Ascher, Dixon Kaufman, et al. “The John S. Najarian symposium: The past, present, and future of surgery and transplantation, May 20, 2022, Minneapolis, MN.” Clin Transplant 37, no. 3 (March 2023): e14877. https://doi.org/10.1111/ctr.14877.
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  - Park, Christine, Tyler Schappe, Sarah Peskoe, Dinushika Mohottige, Norine W. Chan, Nrupen A. Bhavsar, L Ebony Boulware, Jane Pendergast, Allan D. Kirk, and Lisa M. McElroy. “A comparison of deprivation indices and application to transplant populations.” Am J Transplant 23, no. 3 (March 2023): 377–86. https://doi.org/10.1016/j.ajt.2022.11.018.
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  - Mohan, Aditya A., Lyra B. Olson, Ibtehaj A. Naqvi, Sarah A. Morrison, Bryan D. Kraft, Lingye Chen, Loretta G. Que, et al. “Age and Comorbidities Predict COVID-19 Outcome, Regardless of Innate Immune Response Severity: A Single Institutional Cohort Study.” Crit Care Explor 4, no. 12 (December 2022): e0799. https://doi.org/10.1097/CCE.0000000000000799.
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  - Moris, Dimitrios, Ricardo Henao, Hannah Hensman, Linda Stempora, Scott Chasse, Seth Schobel, Christopher J. Dente, Allan D. Kirk, and Eric Elster. “Multidimensional machine learning models predicting outcomes after trauma.” Surgery 172, no. 6 (December 2022): 1851–59. https://doi.org/10.1016/j.surg.2022.08.007.
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  - Shaw, Brian I., Hui-Jie Lee, Robert Ettenger, Paul Grimm, Elaine F. Reed, Minnie Sarwal, Linda Stempora, et al. “Malnutrition and immune cell subsets in children undergoing kidney transplantation.” Pediatr Transplant 26, no. 8 (December 2022): e14371. https://doi.org/10.1111/petr.14371.
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  - Chan, Norine W., Mary Moya-Mendez, Jacqueline B. Henson, Hamed Zaribafzadeh, Mark P. Sendak, Nrupen A. Bhavsar, Suresh Balu, Allan D. Kirk, and Lisa M. McElroy. “Social determinants of health data in solid organ transplantation: National data sources and future directions.” Am J Transplant 22, no. 10 (October 2022): 2293–2301. https://doi.org/10.1111/ajt.17096.
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  - Vicente, Diego A., Seth A. Schobel, Simone Anfossi, Hannah Hensman, Felipe Lisboa, Henry Robertson, Vivek Khatri, et al. “Cellular microRNAs correlate with clinical parameters in multiple injury patients.” J Trauma Acute Care Surg 93, no. 4 (October 1, 2022): 427–38. https://doi.org/10.1097/TA.0000000000003708.
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  - Fitch, Zachary W., Lillian Kang, Jie Li, Stuart J. Knechtle, Joseph W. Turek, Allan D. Kirk, M Louise Markert, and Jean Kwun. “Introducing thymus for promoting transplantation tolerance.” J Allergy Clin Immunol 150, no. 3 (September 2022): 549–56. https://doi.org/10.1016/j.jaci.2022.05.006.
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  - Eckhoff, Austin M., Ashton A. Connor, Julie K. M. Thacker, Dan G. Blazer, Harvey G. Moore, Randall P. Scheri, Sandhya A. Lagoo-Deenadayalan, et al. “A Multidimensional Bioinformatic Platform for the Study of Human Response to Surgery.” Ann Surg 275, no. 6 (June 1, 2022): 1094–1102. https://doi.org/10.1097/SLA.0000000000005429.
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  - Li, Shu, He Xu, Mingqing Song, Brian I. Shaw, Qi-Jing Li, and Allan D. Kirk. “IFI16-STING-NF-κB signaling controls exogenous mitochondrion-induced endothelial activation.” Am J Transplant 22, no. 6 (June 2022): 1578–92. https://doi.org/10.1111/ajt.17034.
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  - Li, Shu, He Xu, and Allan D. Kirk. “Modulation of Xenogeneic T-cell Proliferation by B7 and mTOR Blockade of T Cells and Porcine Endothelial Cells.” Transplantation 106, no. 5 (May 1, 2022): 950–62. https://doi.org/10.1097/TP.0000000000003920.
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  - Kirk, Allan D. “When pigs fly.” Am J Transplant 22, no. 4 (April 2022): 1007–8. https://doi.org/10.1111/ajt.16963.
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  - Martin, Gavin, Clif Flintom, Kate Ulrich, and Allan D. Kirk. “The Accreditation Council for Graduate Medical Education Special Report on Clinical Learners in Procedural Environments: Several Elephants in a Very Small Room.” Anesthesiology 136, no. 2 (February 1, 2022): 265–67. https://doi.org/10.1097/ALN.0000000000004059.
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  - Vicente, Diego, Seth A. Schobel, Simone Anfossi, Hannah Hensman, Felipe Lisboa, Henry Robertson, Vivek Khatri, et al. “Viral Micro-RNAs Are Detected in the Early Systemic Response to Injury and Are Associated With Outcomes in Polytrauma Patients.” Crit Care Med 50, no. 2 (February 1, 2022): 296–306. https://doi.org/10.1097/CCM.0000000000005181.
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  - Walsh, Evan S., Tammy S. Tollison, Hayden N. Brochu, Brian I. Shaw, Kayleigh R. Diveley, Hsuan Chou, Lynn Law, Allan D. Kirk, Michael Gale, and Xinxia Peng. “Single-Cell-Based High-Throughput Ig and TCR Repertoire Sequencing Analysis in Rhesus Macaques.” J Immunol 208, no. 3 (February 1, 2022): 762–71. https://doi.org/10.4049/jimmunol.2100824.
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  - Bradley, Matthew, A. Shi, V. Khatri, S. Schobel, E. Silvius, A. Kirk, T. Buchman, J. Oh, and E. Elster. “Prediction of venous thromboembolism using clinical and serum biomarker data from a military cohort of trauma patients.” Bmj Mil Health 167, no. 6 (December 2021): 402–7. https://doi.org/10.1136/bmjmilitary-2019-001393.
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  - David, Emeraghi, Minghua Zhu, Braden C. Bennett, Daniel Cheng, Paul Schroder, Amanda Nichols, William Parker, Allan D. Kirk, Nancie MacIver, and Eileen T. Chambers. “Undernutrition and Hypoleptinemia Modulate Alloimmunity and CMV-specific Viral Immunity in Transplantation.” Transplantation 105, no. 12 (December 1, 2021): 2554–63. https://doi.org/10.1097/TP.0000000000003743.
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  - Dente, Christopher J., Michael J. Mina, Bryan C. Morse, Hannah Hensman, Seth Schobel, Rondi B. Gelbard, Arnaud Belard, Timothy G. Buchman, Allan D. Kirk, and Eric A. Elster. “Predicting the need for massive transfusion: Prospective validation of a smartphone-based clinical decision support tool.” Surgery 170, no. 5 (November 2021): 1574–80. https://doi.org/10.1016/j.surg.2021.04.034.
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  - Gao, Qimeng, Robert Davis, Zachary Fitch, Michael Mulvihill, Brian Ezekian, Paul Schroder, Robin Schmitz, et al. “Anti-thymoglobulin induction improves neonatal porcine xenoislet engraftment and survival.” Xenotransplantation 28, no. 6 (November 2021): e12713. https://doi.org/10.1111/xen.12713.
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  - Breslin, Adam W., Alexander T. Limkakeng, Elizabeth Silvius, Catherine A. Staton, Chandra Almond, Mary-Beth Joshi, Bartley Adams, et al. “Immune response profiling in patients with traumatic injuries associated with alcohol ingestion.” Clin Transl Sci 14, no. 5 (September 2021): 1791–98. https://doi.org/10.1111/cts.13022.
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  - Xu, He, Hui-Jie Lee, Robin Schmitz, Brian I. Shaw, Shu Li, and Allan D. Kirk. “Age-related effects on thymic output and homeostatic T cell expansion following depletional induction in renal transplant recipients.” Am J Transplant 21, no. 9 (September 2021): 3163–74. https://doi.org/10.1111/ajt.16625.
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  - Shaw, Brian I., Robin Schmitz, Walter J. Flores, Diogo M. Magnani, Jie Li, Mingqing Song, and Allan D. Kirk. “A comparative study of human-and rhesus-specific antithymocyte globulins in Rhesus macaques.” Clin Transplant 35, no. 8 (August 2021): e14369. https://doi.org/10.1111/ctr.14369.
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  - Gelbard, Rondi B., Hannah Hensman, Seth Schobel, Linda L. Stempora, Dimitrios Moris, Christopher J. Dente, Timothy G. Buchman, Allan D. Kirk, and Eric Elster. “An integrative model using flow cytometry identifies nosocomial infection after trauma.” J Trauma Acute Care Surg 91, no. 1 (July 1, 2021): 47–53. https://doi.org/10.1097/TA.0000000000003148.
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  - McElroy, Lisa M., and Allan D. Kirk. “Eudaimonia: An Aristotelian approach to transplantation.” Am J Transplant 21, no. 6 (June 2021): 2014–17. https://doi.org/10.1111/ajt.16487.
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  - Kirk, Allan D., Andrew B. Adams, Antoine Durrbach, Mandy L. Ford, David A. Hildeman, Christian P. Larsen, Flavio Vincenti, David Wojciechowski, and E Steve Woodle. “Optimization of de novo belatacept-based immunosuppression administered to renal transplant recipients.” Am J Transplant 21, no. 5 (May 2021): 1691–98. https://doi.org/10.1111/ajt.16386.
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  - Song, Mingqing, Zachary W. Fitch, Kannan P. Samy, Benjamin M. Martin, Qimeng Gao, Robert Patrick Davis, Francis V. Leopardi, et al. “Coagulation, inflammation, and CD46 transgene expression in neonatal porcine islet xenotransplantation.” Xenotransplantation 28, no. 3 (May 2021): e12680. https://doi.org/10.1111/xen.12680.
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  - Shaw, Brian I., Jaclyn R. Espinosa, Linda Stempora, Allison Miller, Bartley Adams, and Allan D. Kirk. “Functional Characteristics and Phenotypic Plasticity of CD57+PD1- CD4 T Cells and Their Relationship with Transplant Immunosuppression.” J Immunol 206, no. 7 (April 1, 2021): 1668–76. https://doi.org/10.4049/jimmunol.2000736.
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  - Lewis, Sarah S., Becky A. Smith, Ibukunoluwa C. Akinboyo, Jessica Seidelman, Cameron Wolfe, Allan B. Kirk, Gavin Martin, et al. “Early experience with universal preprocedural testing for SARS-CoV-2 in a relatively low-prevalence area.” Infect Control Hosp Epidemiol 42, no. 3 (March 2021): 341–43. https://doi.org/10.1017/ice.2020.398.
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  - Moris, Dimitrios, Jun Wang, Maria Angelica Selim, Mingqing Song, Linda Stempora, William Parker, Allan D. Kirk, and Linda C. Cendales. “Vascularized composite allotransplants as a mechanistic model for allograft rejection - an experimental study.” Transpl Int 34, no. 3 (March 2021): 572–84. https://doi.org/10.1111/tri.13820.
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  - Shaw, Brian I., Hui-Jie Lee, Cliburn Chan, Robert Ettenger, Paul Grimm, Meghan Pearl, Elaine F. Reed, et al. “Relationship between antithymocyte globulin, T cell phenotypes, and clinical outcomes in pediatric kidney transplantation.” Am J Transplant 21, no. 2 (February 2021): 766–75. https://doi.org/10.1111/ajt.16263.
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  - Gerardo, Charles J., Elizabeth Silvius, Seth Schobel, John C. Eppensteiner, Lauren M. McGowan, Eric A. Elster, Allan D. Kirk, and Alexander T. Limkakeng. “Association of a Network of Immunologic Response and Clinical Features With the Functional Recovery From Crotalinae Snakebite Envenoming.” Front Immunol 12 (2021): 628113. https://doi.org/10.3389/fimmu.2021.628113.
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  - Manook, Miriam, Walter J. Flores, Robin Schmitz, Zachary Fitch, Janghoon Yoon, Yeeun Bae, Brian Shaw, et al. “Measuring the Impact of Targeting FcRn-Mediated IgG Recycling on Donor-Specific Alloantibodies in a Sensitized NHP Model.” Front Immunol 12 (2021): 660900. https://doi.org/10.3389/fimmu.2021.660900.
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  - Mosca, P. J., S. Zani, M. M. Haglund, B. H. Collins, S. Wasiolek, T. N. Pappas, A. D. Kirk, and L. C. Cendales. “The Legacy of Joseph A. Moylan, M.D.: "it's about Everyone Else".” Annals of Surgery, January 1, 2021. https://doi.org/10.1097/AS9.0000000000000051.
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  - Schmitz, Robin, Zachary W. Fitch, He Xu, Ada Ghali, Aneesh K. Mehta, Antonio Guasch, and Allan D. Kirk. “Kidney transplantation using alemtuzumab, belatacept, and sirolimus: Five-year follow-up.” Am J Transplant 20, no. 12 (December 2020): 3609–19. https://doi.org/10.1111/ajt.16121.
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  - Calabrese, Leonard H., Roberto Caporali, Christian U. Blank, and Allan D. Kirk. “Modulating the wayward T cell: New horizons with immune checkpoint inhibitor treatments in autoimmunity, transplant, and cancer.” J Autoimmun 115 (December 2020): 102546. https://doi.org/10.1016/j.jaut.2020.102546.
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  - Atia, Andrew, Dimitrios Moris, MacKenzie McRae, Mingqing Song, Linda Stempora, Francis Leopardi, Kyha Williams, et al. “Th17 cell inhibition in a costimulation blockade-based regimen for vascularized composite allotransplantation using a nonhuman primate model.” Transpl Int 33, no. 10 (October 2020): 1294–1301. https://doi.org/10.1111/tri.13612.
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  - Muñoz, Beau, Seth A. Schobel, Felipe A. Lisboa, Vivek Khatri, Scott F. Grey, Christopher J. Dente, Allan D. Kirk, Timothy Buchman, and Eric A. Elster. “Clinical risk factors and inflammatory biomarkers of post-traumatic acute kidney injury in combat patients.” Surgery 168, no. 4 (October 2020): 662–70. https://doi.org/10.1016/j.surg.2020.04.064.
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  - Levitsky, Josh, Bryna E. Burrell, Sai Kanaparthi, Laurence A. Turka, Sunil Kurian, Alberto Sanchez-Fueyo, Juan J. Lozano, et al. “Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus.” Hepatology 72, no. 2 (August 2020): 569–83. https://doi.org/10.1002/hep.31036.
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  - Bradley, Matthew, Christopher Dente, Vivek Khatri, Seth Schobel, Felipe Lisboa, Audrey Shi, Hannah Hensman, Allan Kirk, Timothy G. Buchman, and Eric Elster. “Correction to: Advanced Modeling to Predict Pneumonia in Combat Trauma Patients.” World J Surg 44, no. 7 (July 2020): 2263. https://doi.org/10.1007/s00268-020-05520-3.
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  - Bradley, Matthew, Christopher Dente, Vivek Khatri, Seth Schobel, Felipe Lisboa, Audrey Shi, Hannah Hensman, Allan Kirk, Timothy G. Buchman, and Eric Elster. “Advanced Modeling to Predict Pneumonia in Combat Trauma Patients.” World J Surg 44, no. 7 (July 2020): 2255–62. https://doi.org/10.1007/s00268-019-05294-3.
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  - Kwun, Jean, Jie Li, Clay Rouse, Jae Berm Park, Alton B. Farris, Maragatha Kuchibhatla, Joseph W. Turek, Stuart J. Knechtle, Allan D. Kirk, and M Louise Markert. “Cultured thymus tissue implantation promotes donor-specific tolerance to allogeneic heart transplants.” Jci Insight 5, no. 11 (June 4, 2020). https://doi.org/10.1172/jci.insight.129983.
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  - Lee, Frances T., Anil Dangi, Sahil Shah, Melanie Burnette, Yong-Guang Yang, Allan D. Kirk, Bernhard J. Hering, Stephen D. Miller, and Xunrong Luo. “Rejection of xenogeneic porcine islets in humanized mice is characterized by graft-infiltrating Th17 cells and activated B cells.” Am J Transplant 20, no. 6 (June 2020): 1538–50. https://doi.org/10.1111/ajt.15763.
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  - Manook, Miriam, and Allan D. Kirk. “The best transplant strategy? It depends.” Am J Transplant 20, no. 5 (May 2020): 1221–22. https://doi.org/10.1111/ajt.15821.
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  - Aronson, Solomon, Gavin Martin, Padma Gulur, Mike E. Lipkin, Sandhya A. Lagoo-Deenadayalan, Christopher R. Mantyh, David E. Attarian, Joseph P. Mathew, and Allan D. Kirk. “Preoperative Optimization: A Continued Call to Action.” Anesth Analg 130, no. 4 (April 2020): 808–10. https://doi.org/10.1213/ANE.0000000000004492.
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  - Aronson, Solomon, Sutton Murray, Gavin Martin, Jeanna Blitz, Timothy Crittenden, Mike E. Lipkin, Christopher R. Mantyh, et al. “Roadmap for Transforming Preoperative Assessment to Preoperative Optimization.” Anesth Analg 130, no. 4 (April 2020): 811–19. https://doi.org/10.1213/ANE.0000000000004571.
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  - Dente, Christopher John, Edda Styrmisdottir, Audrey Shi, Seth Schobel, Vivek Khatri, Benjamin K. Potter, Jonathan A. Forsberg, Timothy Buchman, Allan D. Kirk, and Eric Elster. “Driving biology: The effect of standardized wound management on wound biomarker profiles.” J Trauma Acute Care Surg 88, no. 3 (March 2020): 379–89. https://doi.org/10.1097/TA.0000000000002568.
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  - Xu, He, Aneesh K. Mehta, Qimeng Gao, Hui-Jie Lee, Ada Ghali, Antonio Guasch, and Allan D. Kirk. “B cell reconstitution following alemtuzumab induction under a belatacept-based maintenance regimen.” Am J Transplant 20, no. 3 (March 2020): 653–62. https://doi.org/10.1111/ajt.15639.
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  - Blew, Kathryn H., Annabelle Chua, John Foreman, Rasheed Gbadegesin, Annette Jackson, Shashi Nagaraj, Rebecca Sadun, Del Wigfall, Allan D. Kirk, and Eileen T. Chambers. “Tailored use of belatacept in adolescent kidney transplantation.” Am J Transplant 20, no. 3 (March 2020): 884–88. https://doi.org/10.1111/ajt.15611.
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  - Corey, Kristin M., Joshua Helmkamp, Morgan Simons, Lesley Curtis, Keith Marsolo, Suresh Balu, Michael Gao, et al. “Assessing Quality of Surgical Real-World Data from an Automated Electronic Health Record Pipeline.” J Am Coll Surg 230, no. 3 (March 2020): 295-305.e12. https://doi.org/10.1016/j.jamcollsurg.2019.12.005.
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  - Shaw, Brian I., Daniel K. Cheng, Chaitanya R. Acharya, Robert B. Ettenger, Herbert Kim Lyerly, Qing Cheng, Allan D. Kirk, and Eileen T. Chambers. “An age-independent gene signature for monitoring acute rejection in kidney transplantation.” Theranostics 10, no. 15 (2020): 6977–86. https://doi.org/10.7150/thno.42110.
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  - Samy, Kannan P., Qimeng Gao, Robert Patrick Davis, Mingqing Song, Zachary W. Fitch, Michael S. Mulvihill, Andrea L. MacDonald, et al. “The role of human CD46 in early xenoislet engraftment in a dual transplant model.” Xenotransplantation 26, no. 6 (November 2019): e12540. https://doi.org/10.1111/xen.12540.
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  - Lisboa, Felipe A., Christopher J. Dente, Seth A. Schobel, Vivek Khatri, Benjamin K. Potter, Allan D. Kirk, and Eric A. Elster. “Utilizing Precision Medicine to Estimate Timing for Surgical Closure of Traumatic Extremity Wounds.” Ann Surg 270, no. 3 (September 2019): 535–43. https://doi.org/10.1097/SLA.0000000000003470.
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  - Eppensteiner, John, Jean Kwun, Uwe Scheuermann, Andrew Barbas, Alexander T. Limkakeng, Maggie Kuchibhatla, Eric A. Elster, Allan D. Kirk, and Jaewoo Lee. “Damage- and pathogen-associated molecular patterns play differential roles in late mortality after critical illness.” Jci Insight 4, no. 16 (August 22, 2019). https://doi.org/10.1172/jci.insight.127925.
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  - Mulvihill, Michael S., Kannan P. Samy, Qimeng A. Gao, Robin Schmitz, Robert P. Davis, Brian Ezekian, Francis Leopardi, et al. “Secondary lymphoid tissue and costimulation-blockade resistant rejection: A nonhuman primate renal transplant study.” Am J Transplant 19, no. 8 (August 2019): 2350–57. https://doi.org/10.1111/ajt.15365.
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  - Lin, Liwen, He Xu, Muath Bishawi, FeiFei Feng, Kannan Samy, George Truskey, Andrew S. Barbas, Allan D. Kirk, and Todd V. Brennan. “Circulating mitochondria in organ donors promote allograft rejection.” Am J Transplant 19, no. 7 (July 2019): 1917–29. https://doi.org/10.1111/ajt.15309.
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  - Anderson, Douglas J., Denise J. Lo, Francis Leopardi, Mingqing Song, Elizabeth A. Strobert, Joe B. Jenkins, Christian P. Larsen, and Allan D. Kirk. “Corticosteroids and methotrexate as adjuvants to costimulation blockade in non-human primate renal transplantation.” Clin Transplant 33, no. 6 (June 2019): e13568. https://doi.org/10.1111/ctr.13568.
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  - Shaw, Brian I., and Allan D. Kirk. “Kidney Xenotransplantation: Steps toward Clinical Application.” Clin J Am Soc Nephrol 14, no. 4 (April 5, 2019): 620–22. https://doi.org/10.2215/CJN.12471018.
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  - Klintmalm, Goran B., Bruce Kaplan, and Allan D. Kirk. “FDA jeopardizes the lives of lung transplant recipients and in the process severely increases the cost to develop new immunosuppression.” Am J Transplant 19, no. 4 (April 2019): 971–72. https://doi.org/10.1111/ajt.15215.
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  - Lubkin, David T., Muath Bishawi, Andrew S. Barbas, Todd V. Brennan, and Allan D. Kirk. “Extracellular Mitochondrial DNA and N-Formyl Peptides in Trauma and Critical Illness: A Systematic Review.” Crit Care Med 46, no. 12 (December 2018): 2018–28. https://doi.org/10.1097/CCM.0000000000003381.
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  - Kirk, Allan D. “C4: An experiment in academic dialogue.” Am J Transplant 18, no. 11 (November 2018): 2619. https://doi.org/10.1111/ajt.15095.
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  - Darrabie, Marcus D., Jennifer Cheeseman, Alexander T. Limkakeng, Joseph Borawski, Bruce A. Sullenger, Eric A. Elster, Allan D. Kirk, and Jaewoo Lee. “Toll-like receptor activation as a biomarker in traumatically injured patients.” J Surg Res 231 (November 2018): 270–77. https://doi.org/10.1016/j.jss.2018.05.059.
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  - Cendales, Linda C., David S. Ruch, Adela R. Cardones, Guy Potter, Joshua Dooley, Daniel Dore, Jonah Orr, et al. “De novo belatacept in clinical vascularized composite allotransplantation.” Am J Transplant 18, no. 7 (July 2018): 1804–9. https://doi.org/10.1111/ajt.14910.
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  - Belard, Arnaud, Seth Schobel, Matthew Bradley, Benjamin Kyle Potter, Christopher Dente, Timothy Buchman, Allan Kirk, and Eric Elster. “Battlefield to Bedside: Bringing Precision Medicine to Surgical Care.” J Am Coll Surg 226, no. 6 (June 2018): 1093–1102. https://doi.org/10.1016/j.jamcollsurg.2018.02.006.
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  - Samy, K. P., R. P. Davis, Q. Gao, B. M. Martin, M. Song, J. Cano, A. B. Farris, et al. “Early barriers to neonatal porcine islet engraftment in a dual transplant model.” Am J Transplant 18, no. 4 (April 2018): 998–1006. https://doi.org/10.1111/ajt.14601.
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  - Xu, He, Victoria A. Bendersky, Todd V. Brennan, Jaclyn R. Espinosa, and Allan D. Kirk. “IL-7 receptor heterogeneity as a mechanism for repertoire change during postdepletional homeostatic proliferation and its relation to costimulation blockade-resistant rejection.” Am J Transplant 18, no. 3 (March 2018): 720–30. https://doi.org/10.1111/ajt.14589.
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  - Lamanna, Jason J., Juanmarco Gutierrez, Jaclyn R. Espinosa, Jacob Wagner, Lindsey N. Urquia, Cheryl Moreton, C. Victor Hurtig, et al. “Peripheral blood detection of systemic graft-specific xeno-antibodies following transplantation of human neural progenitor cells into the porcine spinal cord.” J Clin Neurosci 48 (February 2018): 173–80. https://doi.org/10.1016/j.jocn.2017.10.033.
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  - Song, M., M. S. Mulvihill, K. D. Williams, B. H. Collins, and A. D. Kirk. “Fatal SV40-associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque.” J Med Primatol 47, no. 1 (February 2018): 81–84. https://doi.org/10.1111/jmp.12285.
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  - “Kwun J, Burghuber C, Manook M, et al. Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates. Blood Adv. 2017;1(24):2115-2119.” Blood Adv 2, no. 2 (January 23, 2018): 89. https://doi.org/10.1182/bloodadvances.2017015446.
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  - Espinosa, Jaclyn R., Danny Mou, Bartley W. Adams, Louis R. DiBernardo, Andrea L. MacDonald, MacKenzie McRae, Allison N. Miller, et al. “T Cell Repertoire Maturation Induced by Persistent and Latent Viral Infection Is Insufficient to Induce Costimulation Blockade Resistant Organ Allograft Rejection in Mice.” Front Immunol 9 (2018): 1371. https://doi.org/10.3389/fimmu.2018.01371.
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  - Kwun, Jean, Jaeberm Park, John S. Yi, Alton B. Farris, Allan D. Kirk, and Stuart J. Knechtle. “IL-21 Biased Alemtuzumab Induced Chronic Antibody-Mediated Rejection Is Reversed by LFA-1 Costimulation Blockade.” Front Immunol 9 (2018): 2323. https://doi.org/10.3389/fimmu.2018.02323.
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  - Kwun, Jean, Christopher Burghuber, Miriam Manook, Brian Ezekian, Jaeberm Park, Janghoon Yoon, John S. Yi, et al. “Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates.” Blood Adv 1, no. 24 (November 14, 2017): 2115–19. https://doi.org/10.1182/bloodadvances.2017010991.
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  - Adams, A. B., J. Goldstein, C. Garrett, R. Zhang, R. E. Patzer, K. A. Newell, N. A. Turgeon, et al. “Belatacept Combined With Transient Calcineurin Inhibitor Therapy Prevents Rejection and Promotes Improved Long-Term Renal Allograft Function.” Am J Transplant 17, no. 11 (November 2017): 2922–36. https://doi.org/10.1111/ajt.14353.
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  - Dente, Christopher J., Matthew Bradley, Seth Schobel, Beverly Gaucher, Timothy Buchman, Allan D. Kirk, and Eric Elster. “Towards precision medicine: Accurate predictive modeling of infectious complications in combat casualties.” J Trauma Acute Care Surg 83, no. 4 (October 2017): 609–16. https://doi.org/10.1097/TA.0000000000001596.
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  - Ettenger, R., H. Chin, K. Kesler, N. Bridges, P. Grimm, E. F. Reed, M. Sarwal, et al. “Relationship Among Viremia/Viral Infection, Alloimmunity, and Nutritional Parameters in the First Year After Pediatric Kidney Transplantation.” Am J Transplant 17, no. 6 (June 2017): 1549–62. https://doi.org/10.1111/ajt.14169.
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  - Samy, K. P., D. J. Anderson, D. J. Lo, M. S. Mulvihill, M. Song, A. B. Farris, B. S. Parker, et al. “Selective Targeting of High-Affinity LFA-1 Does Not Augment Costimulation Blockade in a Nonhuman Primate Renal Transplantation Model.” Am J Transplant 17, no. 5 (May 2017): 1193–1203. https://doi.org/10.1111/ajt.14141.
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  - Belard, Arnaud, Timothy Buchman, Jonathan Forsberg, Benjamin K. Potter, Christopher J. Dente, Allan Kirk, and Eric Elster. “Precision diagnosis: a view of the clinical decision support systems (CDSS) landscape through the lens of critical care.” J Clin Monit Comput 31, no. 2 (April 2017): 261–71. https://doi.org/10.1007/s10877-016-9849-1.
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  - Lee, Jaewoo, Jennifer G. Jackman, Jean Kwun, Miriam Manook, Angelo Moreno, Eric A. Elster, Allan D. Kirk, Kam W. Leong, and Bruce A. Sullenger. “Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis.” Biomaterials 120 (March 2017): 94–102. https://doi.org/10.1016/j.biomaterials.2016.12.024.
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  - Modena, B. D., R. Milam, F. Harrison, J. A. Cheeseman, M. M. Abecassis, J. J. Friedewald, A. D. Kirk, and D. R. Salomon. “Changes in Urinary Microbiome Populations Correlate in Kidney Transplants With Interstitial Fibrosis and Tubular Atrophy Documented in Early Surveillance Biopsies.” Am J Transplant 17, no. 3 (March 2017): 712–23. https://doi.org/10.1111/ajt.14038.
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  - Zheng, H. B., B. Watkins, V. Tkachev, S. Yu, D. Tran, S. Furlan, K. Zeleski, et al. “The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques.” Am J Transplant 17, no. 3 (March 2017): 657–70. https://doi.org/10.1111/ajt.14006.
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  - Roedder, Silke, Tara Sigdel, Szu-Chuan Hsieh, Jennifer Cheeseman, Diana Metes, Camila Macedo, Elaine F. Reed, et al. “Expression of Mitochondrial-Encoded Genes in Blood Differentiate Acute Renal Allograft Rejection.” Front Med (Lausanne) 4 (2017): 185. https://doi.org/10.3389/fmed.2017.00185.
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  - George, Roshan P., Aneesh K. Mehta, Sebastian D. Perez, Pamela Winterberg, Jennifer Cheeseman, Brandi Johnson, Jean Kwun, et al. “Premature T Cell Senescence in Pediatric CKD.” J Am Soc Nephrol 28, no. 1 (January 2017): 359–67. https://doi.org/10.1681/ASN.2016010053.
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  - Land, W. G., P. Agostinis, S. Gasser, A. D. Garg, and A. Linkermann. “DAMP-Induced Allograft and Tumor Rejection: The Circle Is Closing.” Am J Transplant 16, no. 12 (December 2016): 3322–37. https://doi.org/10.1111/ajt.14012.
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  - Klintmalm, G. B., F. Vincenti, and A. Kirk. “Steroid-Responsive Acute Rejection Should Not Be the End Point for Immunosuppressive Trials.” Am J Transplant 16, no. 11 (November 2016): 3077–78. https://doi.org/10.1111/ajt.13889.
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  - Buchman, Timothy G., Timothy R. Billiar, Eric Elster, Allan D. Kirk, Ramzy H. Rimawi, Yoram Vodovotz, and Barbara A. Zehnbauer. “Precision Medicine for Critical Illness and Injury.” Crit Care Med 44, no. 9 (September 2016): 1635–38. https://doi.org/10.1097/CCM.0000000000002028.
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  - Chinnadurai, Raghavan, Ian B. Copland, Marco A. Garcia, Christopher T. Petersen, Christopher N. Lewis, Edmund K. Waller, Allan D. Kirk, and Jacques Galipeau. “Cryopreserved Mesenchymal Stromal Cells Are Susceptible to T-Cell Mediated Apoptosis Which Is Partly Rescued by IFNγ Licensing.” Stem Cells 34, no. 9 (September 2016): 2429–42. https://doi.org/10.1002/stem.2415.
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  - Kirk, A. D., P. S. Malchesky, R. Shapiro, S. A. Webber, H. H. Hirsch, F. M. Marty, R. Oberbauer, et al. “Introducing the Wiley Transplant Peer Review Network.” Am J Transplant 16, no. 9 (September 2016): 2505–7. https://doi.org/10.1111/ajt.13965.
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  - Oh, B., J. Yoon, A. Farris, A. Kirk, S. Knechtle, and J. Kwun. “Rapamycin Interferes With Postdepletion Regulatory T Cell Homeostasis and Enhances DSA Formation Corrected by CTLA4-Ig.” Am J Transplant 16, no. 9 (September 2016): 2612–23. https://doi.org/10.1111/ajt.13789.
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  - “Introducing the Wiley Transplant Peer Review Network.” Transpl Int 29, no. 8 (August 2016): 839–41. https://doi.org/10.1111/tri.12812.
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  - Kirk, Allan D., Paul S. Malchesky, Ron Shapiro, Steven A. Webber, Hans H. Hirsch, Francisco M. Marty, Rainer Oberbauer, et al. “Introducing The Wiley Transplant Peer Review Network.” Artif Organs 40, no. 7 (July 2016): 635–37. https://doi.org/10.1111/aor.12772.
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  - Espinosa, Jaclyn R., Kannan P. Samy, and Allan D. Kirk. “Memory T cells in organ transplantation: progress and challenges.” Nat Rev Nephrol 12, no. 6 (June 2016): 339–47. https://doi.org/10.1038/nrneph.2016.9.
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  - Anderson, D. J., D. J. Lo, F. Leopardi, M. Song, N. A. Turgeon, E. A. Strobert, J. B. Jenkins, et al. “Anti-Leukocyte Function-Associated Antigen 1 Therapy in a Nonhuman Primate Renal Transplant Model of Costimulation Blockade-Resistant Rejection.” Am J Transplant 16, no. 5 (May 2016): 1456–64. https://doi.org/10.1111/ajt.13628.
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  - Espinosa, J., F. Herr, G. Tharp, S. Bosinger, M. Song, A. B. Farris, R. George, et al. “CD57(+) CD4 T Cells Underlie Belatacept-Resistant Allograft Rejection.” Am J Transplant 16, no. 4 (April 2016): 1102–12. https://doi.org/10.1111/ajt.13613.
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  - Xu, H., K. P. Samy, A. Guasch, S. I. Mead, A. Ghali, A. Mehta, L. Stempora, and A. D. Kirk. “Postdepletion Lymphocyte Reconstitution During Belatacept and Rapamycin Treatment in Kidney Transplant Recipients.” Am J Transplant 16, no. 2 (February 2016): 550–64. https://doi.org/10.1111/ajt.13469.
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  - Cooper, David K. C., Rita Bottino, Pierre Gianello, Melanie Graham, Wayne J. Hawthorne, Allan D. Kirk, Olle Korsgren, Chung-Gyu Park, and Collin Weber. “First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 4: pre-clinical efficacy and complication data required to justify a clinical trial.” Xenotransplantation 23, no. 1 (2016): 46–52. https://doi.org/10.1111/xen.12226.
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  - Dorr, Casey R., Barry I. Freedman, Pamela J. Hicks, W Mark Brown, Gregory B. Russell, Bruce A. Julian, Stephen O. Pastan, et al. “Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes.” Plos One 11, no. 4 (2016): e0152775. https://doi.org/10.1371/journal.pone.0152775.
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  - Freedman, Barry I., Stephen O. Pastan, Ajay K. Israni, David Schladt, Bruce A. Julian, Michael D. Gautreaux, Vera Hauptfeld, et al. “APOL1 Genotype and Kidney Transplantation Outcomes From Deceased African American Donors.” Transplantation 100, no. 1 (January 2016): 194–202. https://doi.org/10.1097/TP.0000000000000969.
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  - Newell, K. A., A. Asare, I. Sanz, C. Wei, A. Rosenberg, Z. Gao, S. Kanaparthi, et al. “Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients.” Am J Transplant 15, no. 11 (November 2015): 2908–20. https://doi.org/10.1111/ajt.13480.
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  - Elder, Robert W., Roshan P. George, Nancy M. McCabe, Fred H. Rodriguez, Wendy M. Book, William T. Mahle, and Allan D. Kirk. “Immunologic Aging in Adults with Congenital Heart Disease: Does Infant Sternotomy Matter?” Pediatr Cardiol 36, no. 7 (October 2015): 1411–16. https://doi.org/10.1007/s00246-015-1174-9.
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  - Forsberg, Jonathan A., Benjamin K. Potter, Matthew B. Wagner, Andrew Vickers, Christopher J. Dente, Allan D. Kirk, and Eric A. Elster. “Lessons of War: Turning Data Into Decisions.” Ebiomedicine 2, no. 9 (September 2015): 1235–42. https://doi.org/10.1016/j.ebiom.2015.07.022.
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  - Ma, Jun, Jasmin Divers, Nicholette D. Palmer, Bruce A. Julian, Ajay K. Israni, David Schladt, Stephen O. Pastan, et al. “Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantation.” Kidney Int 88, no. 3 (September 2015): 584–92. https://doi.org/10.1038/ki.2015.105.
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  - Cendales, L., R. Bray, H. Gebel, L. Brewster, R. Elbein, D. Farthing, M. Song, et al. “Tacrolimus to Belatacept Conversion Following Hand Transplantation: A Case Report.” Am J Transplant 15, no. 8 (August 2015): 2250–55. https://doi.org/10.1111/ajt.13217.
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  - Freitas, A. M., K. P. Samy, A. B. Farris, F. V. Leopardi, M. Song, L. Stempora, E. A. Strobert, J. A. Jenkins, A. D. Kirk, and L. C. Cendales. “Studies Introducing Costimulation Blockade for Vascularized Composite Allografts in Nonhuman Primates.” Am J Transplant 15, no. 8 (August 2015): 2240–49. https://doi.org/10.1111/ajt.13379.
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  - Suessmuth, Y., R. Mukherjee, B. Watkins, D. T. Koura, K. Finstermeier, C. Desmarais, L. Stempora, et al. “CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRbeta repertoire.” Blood 125 (June 18, 2015): 3835–50.
  - Suessmuth, Yvonne, Rithun Mukherjee, Benjamin Watkins, Divya T. Koura, Knut Finstermeier, Cindy Desmarais, Linda Stempora, et al. “CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire.” Blood 125, no. 25 (June 18, 2015): 3835–50. https://doi.org/10.1182/blood-2015-03-631853.
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  - Mou, Danny, Jaclyn E. Espinosa, Linda Stempora, Neal N. Iwakoshi, and Allan D. Kirk. “Viral-induced CD28 loss evokes costimulation independent alloimmunity.” J Surg Res 196, no. 2 (June 15, 2015): 241–46. https://doi.org/10.1016/j.jss.2015.02.033.
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  - Beasley, Georgia M., Theodore N. Pappas, and Allan D. Kirk. “Procedure Delegation by Attending Surgeons Performing Concurrent Operations in Academic Medical Centers: Balancing Safety and Efficiency.” Ann Surg 261, no. 6 (June 2015): 1044–45. https://doi.org/10.1097/SLA.0000000000001208.
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  - Freedman, B. I., B. A. Julian, S. O. Pastan, A. K. Israni, D. Schladt, M. D. Gautreaux, V. Hauptfeld, et al. “Apolipoprotein L1 gene variants in deceased organ donors are associated with renal allograft failure.” Am J Transplant 15, no. 6 (June 2015): 1615–22. https://doi.org/10.1111/ajt.13223.
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  - Martin, B. M., K. P. Samy, M. C. Lowe, P. W. Thompson, J. Cano, A. B. Farris, M. Song, et al. “Dual islet transplantation modeling of the instant blood-mediated inflammatory reaction.” Am J Transplant 15, no. 5 (May 2015): 1241–52. https://doi.org/10.1111/ajt.13098.
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  - Lo, D. J., D. J. Anderson, M. Song, F. Leopardi, A. B. Farris, E. Strobert, S. Chapin, B. Devens, E. Karrer, and A. D. Kirk. “A pilot trial targeting the ICOS-ICOS-L pathway in nonhuman primate kidney transplantation.” Am J Transplant 15, no. 4 (April 2015): 984–92. https://doi.org/10.1111/ajt.13100.
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  - Velazquez, Victoria M., Luke S. Uebelhoer, Manoj Thapa, Chris C. Ibegbu, Cynthia Courtney, Steven E. Bosinger, Joseph F. Magliocca, et al. “Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development.” Hepatology 61, no. 3 (March 2015): 843–56. https://doi.org/10.1002/hep.27575.
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  - Singh, K., L. Stempora, R. D. Harvey, A. D. Kirk, C. P. Larsen, B. R. Blazar, and L. S. Kean. “Superiority of rapamycin over tacrolimus in preserving nonhuman primate Treg half-life and phenotype after adoptive transfer.” Am J Transplant 14, no. 12 (December 2014): 2691–2703. https://doi.org/10.1111/ajt.12934.
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  - Gupta, Nitika A., Vasantha L. Kolachala, Rong Jiang, Carlos Abramowsky, Asha Shenoi, Astrid Kosters, Haritha Pavuluri, Frank Anania, and Allan D. Kirk. “Mitigation of autophagy ameliorates hepatocellular damage following ischemia-reperfusion injury in murine steatotic liver.” Am J Physiol Gastrointest Liver Physiol 307, no. 11 (December 1, 2014): G1088–99. https://doi.org/10.1152/ajpgi.00210.2014.
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  - Mou, D., J. Espinosa, D. J. Lo, and A. D. Kirk. “CD28 negative T cells: is their loss our gain?” Am J Transplant 14, no. 11 (November 2014): 2460–66. https://doi.org/10.1111/ajt.12937.
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  - Roedder, Silke, Tara Sigdel, Nathan Salomonis, Sue Hsieh, Hong Dai, Oriol Bestard, Diana Metes, et al. “The kSORT assay to detect renal transplant patients at high risk for acute rejection: results of the multicenter AART study.” Plos Med 11, no. 11 (November 2014): e1001759. https://doi.org/10.1371/journal.pmed.1001759.
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  - Chinnadurai, Raghavan, Marco A. Garcia, Yumiko Sakurai, Wilbur A. Lam, Allan D. Kirk, Jacques Galipeau, and Ian B. Copland. “Actin cytoskeletal disruption following cryopreservation alters the biodistribution of human mesenchymal stromal cells in vivo.” Stem Cell Reports 3, no. 1 (July 8, 2014): 60–72. https://doi.org/10.1016/j.stemcr.2014.05.003.
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  - Kirk, A. D., A. Guasch, H. Xu, J. Cheeseman, S. I. Mead, A. Ghali, A. K. Mehta, et al. “Renal transplantation using belatacept without maintenance steroids or calcineurin inhibitors.” Am J Transplant 14, no. 5 (May 2014): 1142–51. https://doi.org/10.1111/ajt.12712.
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  - Neujahr, D. C., K. Uppal, S. D. Force, F. Fernandez, C. Lawrence, A. Pickens, R. Bag, et al. “Bile acid aspiration associated with lung chemical profile linked to other biomarkers of injury after lung transplantation.” Am J Transplant 14, no. 4 (April 2014): 841–48. https://doi.org/10.1111/ajt.12631.
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  - O’Leary, J. G., A. J. Demetris, L. S. Friedman, H. M. Gebel, P. F. Halloran, A. D. Kirk, S. J. Knechtle, et al. “The role of donor-specific HLA alloantibodies in liver transplantation.” Am J Transplant 14, no. 4 (April 2014): 779–87. https://doi.org/10.1111/ajt.12667.
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  - Lo, Denise J., Bruce Kaplan, and Allan D. Kirk. “Biomarkers for kidney transplant rejection.” Nat Rev Nephrol 10, no. 4 (April 2014): 215–25. https://doi.org/10.1038/nrneph.2013.281.
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  - Krummey, S. M., J. A. Cheeseman, J. A. Conger, P. S. Jang, A. K. Mehta, A. D. Kirk, C. P. Larsen, and M. L. Ford. “High CTLA-4 expression on Th17 cells results in increased sensitivity to CTLA-4 coinhibition and resistance to belatacept.” Am J Transplant 14, no. 3 (March 2014): 607–14. https://doi.org/10.1111/ajt.12600.
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  - Rosenblum, Joshua M., and Allan D. Kirk. “Recollective homeostasis and the immune consequences of peritransplant depletional induction therapy.” Immunol Rev 258, no. 1 (March 2014): 167–82. https://doi.org/10.1111/imr.12155.
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  - Xu, H., S. D. Perez, J. Cheeseman, A. K. Mehta, and A. D. Kirk. “The allo- and viral-specific immunosuppressive effect of belatacept, but not tacrolimus, attenuates with progressive T cell maturation.” Am J Transplant 14, no. 2 (February 2014): 319–32. https://doi.org/10.1111/ajt.12574.
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  - Kim, E. J., J. Kwun, A. C. Gibby, J. J. Hong, A. B. Farris, N. N. Iwakoshi, F. Villinger, A. D. Kirk, and S. J. Knechtle. “Costimulation blockade alters germinal center responses and prevents antibody-mediated rejection.” Am J Transplant 14, no. 1 (January 2014): 59–69. https://doi.org/10.1111/ajt.12526.
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  - Samy, Kannan P., Benjamin M. Martin, Nicole A. Turgeon, and Allan D. Kirk. “Islet cell xenotransplantation: a serious look toward the clinic.” Xenotransplantation 21, no. 3 (2014): 221–29. https://doi.org/10.1111/xen.12095.
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  - Lo, D. J., A. B. Farris, M. Song, F. Leopardi, D. J. Anderson, E. A. Strobert, S. Ramakrishnan, et al. “Inhibition of αvβ6 promotes acute renal allograft rejection in nonhuman primates.” Am J Transplant 13, no. 12 (December 2013): 3085–93. https://doi.org/10.1111/ajt.12467.
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  - Koura, Divya T., John T. Horan, Amelia A. Langston, Muna Qayed, Aneesh Mehta, Hanna J. Khoury, R Donald Harvey, et al. “In vivo T cell costimulation blockade with abatacept for acute graft-versus-host disease prevention: a first-in-disease trial.” Biol Blood Marrow Transplant 19, no. 11 (November 2013): 1638–49. https://doi.org/10.1016/j.bbmt.2013.09.003.
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  - Pena, Juan A., Lauren Titus, Jennifer Jackson, Allan D. Kirk, and Jennifer L. Gooch. “Differential regulation of calcineurin isoforms in transplant patients: a new look at an old problem.” Transplantation 96, no. 3 (August 15, 2013): 239–44. https://doi.org/10.1097/TP.0b013e31829acb64.
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  - O’Leary, J. G., H. M. Gebel, R. Ruiz, R. A. Bray, J. D. Marr, X. J. Zhou, S. M. Shiller, B. M. Susskind, A. D. Kirk, and G. B. Klintmalm. “Class II alloantibody and mortality in simultaneous liver-kidney transplantation.” Am J Transplant 13, no. 4 (April 2013): 954–60. https://doi.org/10.1111/ajt.12147.
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  - Lo, D. J., D. J. Anderson, T. A. Weaver, F. Leopardi, M. Song, A. B. Farris, E. A. Strobert, et al. “Belatacept and sirolimus prolong nonhuman primate renal allograft survival without a requirement for memory T cell depletion.” Am J Transplant 13, no. 2 (February 2013): 320–28. https://doi.org/10.1111/j.1600-6143.2012.04342.x.
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  - Lowe, M. C., I. R. Badell, A. P. Turner, P. W. Thompson, F. V. Leopardi, E. A. Strobert, C. P. Larsen, and A. D. Kirk. “Belatacept and sirolimus prolong nonhuman primate islet allograft survival: adverse consequences of concomitant alefacept therapy.” Am J Transplant 13, no. 2 (February 2013): 312–19. https://doi.org/10.1111/j.1600-6143.2012.04341.x.
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  - Beus, Jonathan M., Salila S. Hashmi, Saranya A. Selvaraj, Danxia Duan, Linda L. Stempora, Stephanie A. Monday, Jennifer A. Cheeseman, et al. “Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection.” Plos One 8, no. 8 (2013): e71221. https://doi.org/10.1371/journal.pone.0071221.
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  - Velazquez, Victoria M., Huiming Hon, Chris Ibegbu, Stuart J. Knechtle, Allan D. Kirk, and Arash Grakoui. “Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection.” Hepatology 56, no. 6 (December 2012): 2071–81. https://doi.org/10.1002/hep.25904.
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  - Sam, Wai-Johnn, Christine E. Chamberlain, Su-Jun Lee, Joyce A. Goldstein, Douglas A. Hale, Roslyn B. Mannon, Allan D. Kirk, and Yuen Yi Hon. “Associations of ABCB1 and IL-10 genetic polymorphisms with sirolimus-induced dyslipidemia in renal transplant recipients.” Transplantation 94, no. 9 (November 15, 2012): 971–77. https://doi.org/10.1097/TP.0b013e31826b55e2.
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  - Charafeddine, A. H., E. J. Kim, D. M. Maynard, H. Yi, T. A. Weaver, M. Gunay-Aygun, M. Russell, W. A. Gahl, and A. D. Kirk. “Platelet-derived CD154: ultrastructural localization and clinical correlation in organ transplantation.” Am J Transplant 12, no. 11 (November 2012): 3143–51. https://doi.org/10.1111/j.1600-6143.2012.04241.x.
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  - Gupta, Nitika A., Vasantha L. Kolachala, Rong Jiang, Carlos Abramowsky, Rene Romero, Nimita Fifadara, Frank Anania, Stuart Knechtle, and Allan Kirk. “The glucagon-like peptide-1 receptor agonist Exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis.” Am J Pathol 181, no. 5 (November 2012): 1693–1701. https://doi.org/10.1016/j.ajpath.2012.07.015.
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  - Kwun, J., B. C. Oh, A. C. Gibby, R. Ruhil, V. T. Lu, D. W. Kim, E. K. Page, et al. “Patterns of de novo allo B cells and antibody formation in chronic cardiac allograft rejection after alemtuzumab treatment.” Am J Transplant 12, no. 10 (October 2012): 2641–51. https://doi.org/10.1111/j.1600-6143.2012.04181.x.
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  - Lowe, M., I. R. Badell, P. Thompson, B. Martin, F. Leopardi, E. Strobert, A. A. Price, et al. “A novel monoclonal antibody to CD40 prolongs islet allograft survival.” Am J Transplant 12, no. 8 (August 2012): 2079–87. https://doi.org/10.1111/j.1600-6143.2012.04054.x.
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  - Badell, I. R., M. C. Russell, K. Cardona, V. O. Shaffer, A. P. Turner, J. G. Avila, J. A. Cano, et al. “CTLA4Ig prevents alloantibody formation following nonhuman primate islet transplantation using the CD40-specific antibody 3A8.” Am J Transplant 12, no. 7 (July 2012): 1918–23. https://doi.org/10.1111/j.1600-6143.2012.04029.x.
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  - Ramakrishnan, S. K., A. Page, A. B. Farris, K. Singh, F. Leopardi, K. Hamby, S. Sen, et al. “Evidence for kidney rejection after combined bone marrow and renal transplantation despite ongoing whole-blood chimerism in rhesus macaques.” Am J Transplant 12, no. 7 (July 2012): 1755–64. https://doi.org/10.1111/j.1600-6143.2012.04045.x.
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  - Thompson, P., I. R. Badell, M. Lowe, A. Turner, J. Cano, J. Avila, A. Azimzadeh, et al. “Alternative immunomodulatory strategies for xenotransplantation: CD40/154 pathway-sparing regimens promote xenograft survival.” Am J Transplant 12, no. 7 (July 2012): 1765–75. https://doi.org/10.1111/j.1600-6143.2012.04031.x.
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  - Singh, K., N. Kozyr, L. Stempora, A. D. Kirk, C. P. Larsen, B. R. Blazar, and L. S. Kean. “Regulatory T cells exhibit decreased proliferation but enhanced suppression after pulsing with sirolimus.” Am J Transplant 12, no. 6 (June 2012): 1441–57. https://doi.org/10.1111/j.1600-6143.2011.03963.x.
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  - Turgeon, Nicole A., Sebastian Perez, Max Mondestin, S Scott Davis, Edward Lin, Sudha Tata, Allan D. Kirk, Christian P. Larsen, Thomas C. Pearson, and John F. Sweeney. “The impact of renal function on outcomes of bariatric surgery.” J Am Soc Nephrol 23, no. 5 (May 2012): 885–94. https://doi.org/10.1681/ASN.2011050476.
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  - Neujahr, D. C., S. D. Perez, A. Mohammed, O. Ulukpo, E. C. Lawrence, F. Fernandez, A. Pickens, et al. “Cumulative exposure to gamma interferon-dependent chemokines CXCL9 and CXCL10 correlates with worse outcome after lung transplant.” Am J Transplant 12, no. 2 (February 2012): 438–46. https://doi.org/10.1111/j.1600-6143.2011.03857.x.
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  - Badell, I. R., P. W. Thompson, A. P. Turner, M. C. Russell, J. G. Avila, J. A. Cano, J. M. Robertson, et al. “Nondepleting anti-CD40-based therapy prolongs allograft survival in nonhuman primates.” Am J Transplant 12, no. 1 (January 2012): 126–35. https://doi.org/10.1111/j.1600-6143.2011.03736.x.
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  - Page, A., S. Srinivasan, K. Singh, M. Russell, K. Hamby, T. Deane, S. Sen, et al. “CD40 blockade combines with CTLA4Ig and sirolimus to produce mixed chimerism in an MHC-defined rhesus macaque transplant model.” Am J Transplant 12, no. 1 (January 2012): 115–25. https://doi.org/10.1111/j.1600-6143.2011.03737.x.
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  - Kitchens, W. H., D. Haridas, M. E. Wagener, M. Song, A. D. Kirk, C. P. Larsen, and M. L. Ford. “Integrin antagonists prevent costimulatory blockade-resistant transplant rejection by CD8(+) memory T cells.” Am J Transplant 12, no. 1 (January 2012): 69–80. https://doi.org/10.1111/j.1600-6143.2011.03762.x.
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  - Sam, Wai-Johnn, Christine E. Chamberlain, Su-Jun Lee, Joyce A. Goldstein, Douglas A. Hale, Roslyn B. Mannon, Allan D. Kirk, and Yuen Yi Hon. “Associations of ABCB1 3435C>T and IL-10-1082G>A polymorphisms with long-term sirolimus dose requirements in renal transplant patients.” Transplantation 92, no. 12 (December 27, 2011): 1342–47. https://doi.org/10.1097/TP.0b013e3182384ae2.
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  - Ferrer, Ivana R., Maylene E. Wagener, Minqing Song, Allan D. Kirk, Christian P. Larsen, and Mandy L. Ford. “Antigen-specific induced Foxp3+ regulatory T cells are generated following CD40/CD154 blockade.” Proc Natl Acad Sci U S A 108, no. 51 (December 20, 2011): 20701–6. https://doi.org/10.1073/pnas.1105500108.
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  - Mohammed, A., O. Ulukpo, E. C. Lawrence, F. Fernandez, A. Pickens, A. A. Gal, S. D. Force, et al. “Cumulative exposure to CD8+ granzyme Bhi T cells is associated with reduced lung function early after lung transplantation.” Transplant Proc 43, no. 10 (December 2011): 3892–98. https://doi.org/10.1016/j.transproceed.2011.09.072.
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  - Thompson, P., I. R. Badell, M. Lowe, J. Cano, M. Song, F. Leopardi, J. Avila, et al. “Islet xenotransplantation using gal-deficient neonatal donors improves engraftment and function.” Am J Transplant 11, no. 12 (December 2011): 2593–2602. https://doi.org/10.1111/j.1600-6143.2011.03720.x.
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  - Reisman, Natalie M., Tamara L. Floyd, Maylene E. Wagener, Allan D. Kirk, Christian P. Larsen, and Mandy L. Ford. “LFA-1 blockade induces effector and regulatory T-cell enrichment in lymph nodes and synergizes with CTLA-4Ig to inhibit effector function.” Blood 118, no. 22 (November 24, 2011): 5851–61. https://doi.org/10.1182/blood-2011-04-347252.
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  - Jackson, J. A., E. J. Kim, B. Begley, J. Cheeseman, T. Harden, S. D. Perez, S. Thomas, B. Warshaw, and A. D. Kirk. “Urinary chemokines CXCL9 and CXCL10 are noninvasive markers of renal allograft rejection and BK viral infection.” Am J Transplant 11, no. 10 (October 2011): 2228–34. https://doi.org/10.1111/j.1600-6143.2011.03680.x.
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  - Bradley, J. A., W. M. Baldwin, A. Bingaman, C. Ellenrieder, H. M. Gebel, D. Glotz, and A. D. Kirk. “Antibody-mediated rejection--an ounce of prevention is worth a pound of cure.” Am J Transplant 11, no. 6 (June 2011): 1131–39. https://doi.org/10.1111/j.1600-6143.2011.03581.x.
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  - Thompson, P., K. Cardona, M. Russell, I. R. Badell, V. Shaffer, G. Korbutt, G. R. Rayat, et al. “CD40-specific costimulation blockade enhances neonatal porcine islet survival in nonhuman primates.” Am J Transplant 11, no. 5 (May 2011): 947–57. https://doi.org/10.1111/j.1600-6143.2011.03509.x.
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  - Turner, A. P., V. O. Shaffer, K. Araki, C. Martens, P. L. Turner, S. Gangappa, M. L. Ford, R. Ahmed, A. D. Kirk, and C. P. Larsen. “Sirolimus enhances the magnitude and quality of viral-specific CD8+ T-cell responses to vaccinia virus vaccination in rhesus macaques.” Am J Transplant 11, no. 3 (March 2011): 613–18. https://doi.org/10.1111/j.1600-6143.2010.03407.x.
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  - Lo, Denise J., Tim A. Weaver, David E. Kleiner, Roslyn B. Mannon, Lynn M. Jacobson, Bryan N. Becker, S John Swanson, Douglas A. Hale, and Allan D. Kirk. “Chemokines and their receptors in human renal allotransplantation.” Transplantation 91, no. 1 (January 15, 2011): 70–77. https://doi.org/10.1097/TP.0b013e3181fe12fc.
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  - Lo, D. J., T. A. Weaver, L. Stempora, A. K. Mehta, M. L. Ford, C. P. Larsen, and A. D. Kirk. “Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression.” Am J Transplant 11, no. 1 (January 2011): 22–33. https://doi.org/10.1111/j.1600-6143.2010.03317.x.
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  - Badell, Idelberto R., Maria C. Russell, Peter W. Thompson, Alexandra P. Turner, Tim A. Weaver, Jennifer M. Robertson, Jose G. Avila, et al. “LFA-1-specific therapy prolongs allograft survival in rhesus macaques.” J Clin Invest 120, no. 12 (December 2010): 4520–31. https://doi.org/10.1172/JCI43895.
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  - Kirk, Allan D., Nicole A. Turgeon, and Neal N. Iwakoshi. “B cells and transplantation tolerance.” Nat Rev Nephrol 6, no. 10 (October 2010): 584–93. https://doi.org/10.1038/nrneph.2010.111.
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  - Neujahr, David C., Aminu Mohammed, Onome Ulukpo, Seth D. Force, Allan M. Ramirez, Andres Pelaez, E Clinton Lawrence, Christian P. Larsen, and Allan D. Kirk. “Surgical correction of gastroesophageal reflux in lung transplant patients is associated with decreased effector CD8 cells in lung lavages: a case series.” Chest 138, no. 4 (October 2010): 937–43. https://doi.org/10.1378/chest.09-2888.
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  - Kirk, Allan, and Terry B. Strom. “Immunogenetics and transplantation.” Curr Opin Immunol 22, no. 5 (October 2010): 631–33. https://doi.org/10.1016/j.coi.2010.09.003.
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  - Turgeon, N. A., J. G. Avila, J. A. Cano, J. J. Hutchinson, I. R. Badell, A. J. Page, A. B. Adams, et al. “Experience with a novel efalizumab-based immunosuppressive regimen to facilitate single donor islet cell transplantation.” Am J Transplant 10, no. 9 (September 2010): 2082–91. https://doi.org/10.1111/j.1600-6143.2010.03212.x.
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  - Ferrer, Ivana R., Maylene E. Wagener, Jennifer M. Robertson, Alexa P. Turner, Koichi Araki, Rafi Ahmed, Allan D. Kirk, Christian P. Larsen, and Mandy L. Ford. “Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses.” J Immunol 185, no. 4 (August 15, 2010): 2004–8. https://doi.org/10.4049/jimmunol.1001176.
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  - Newell, Kenneth A., Adam Asare, Allan D. Kirk, Trang D. Gisler, Kasia Bourcier, Manikkam Suthanthiran, William J. Burlingham, et al. “Identification of a B cell signature associated with renal transplant tolerance in humans.” J Clin Invest 120, no. 6 (June 2010): 1836–47. https://doi.org/10.1172/JCI39933.
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  - Floyd, Tamara L., Steven B. Orr, Shana M. Coley, Samantha S. Hanna, Maylene E. Wagener, Allan D. Kirk, Christian P. Larsen, and Mandy L. Ford. “High-frequency alloreactive T cells augment effector function of low-frequency CD8+ T-cell responses under CD28/CD154 blockade.” Transplantation 89, no. 10 (May 27, 2010): 1208–17. https://doi.org/10.1097/TP.0b013e3181df53dc.
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  - Radziewicz, Henry, Chris C. Ibegbu, Huiming Hon, Nathalie Bédard, Julie Bruneau, Kimberly A. Workowski, Stuart J. Knechtle, et al. “Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling.” J Immunol 184, no. 5 (March 1, 2010): 2410–22. https://doi.org/10.4049/jimmunol.0902994.
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  - Bertrand, Y., F. Baleydier, J. Hughes, A. Jefferson, E. Raynaud De Mauverger, G. Fernandez, I. Lowy, et al. “Diagnosis of immune deficiency in childhood.” Revue Francophone Des Laboratoires 2010, no. 424 (January 1, 2010): 53–58. https://doi.org/10.1016/s1773-035x(10)70609-2.
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  - Béné, M. C., M. Labalette, G. Faure, B. Drenou, F. Geneviève, P. Lepelley, M. Le Garff-Tavernier, et al. “Report on the rating of flow cytometric immunophenotyping.” Revue Francophone Des Laboratoires 2010, no. 424 (January 1, 2010): 59–60. https://doi.org/10.1016/s1773-035x(10)70610-9.
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  - Chevailler, A., M. N. Kolopp-Sarda, J. Hughes, A. Jefferson, E. Raynaud De Mauverger, G. Fernandez, I. Lowy, et al. “Immunology: News 2010. Foreword.” Revue Francophone Des Laboratoires 2010, no. 424 (January 1, 2010): 29–30. https://doi.org/10.1016/S1773-035X(10)70606-7.
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  - Corvaisier-Chiron, M., C. Beauvillain, J. Hughes, A. Jefferson, E. Raynaud De Mauverger, G. Fernandez, I. Lowy, et al. “T regulator and Th17 lymphocytes: Physiological and pathological functions.” Revue Francophone Des Laboratoires 2010, no. 424 (January 1, 2010): 31–40. https://doi.org/10.1016/s1773-035x(10)70607-9.
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  - Hughes, J., A. Jefferson, E. Raynaud De Mauverger, G. Fernandez, I. Lowy, D. Molrine, B. Vingert, et al. “Editorial: The Study Group for Autoimmune Diseases (GEAI) took off...” Revue Francophone Des Laboratoires 2010, no. 424 (January 1, 2010): 3. https://doi.org/10.1016/s1773-035x(10)70578-5.
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  - Jeannin, P., S. Jaillon, Y. Delneste, J. Hughes, A. Jefferson, E. Raynaud De Mauverger, G. Fernandez, et al. “Biology of innate immune receptors: Clinical and diagnostic applications.” Revue Francophone Des Laboratoires 2010, no. 424 (January 1, 2010): 41–51. https://doi.org/10.1016/s1773-035x(10)70608-0.
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  - Naudin, C., J. Hughes, A. Jefferson, E. Raynaud De Mauverger, G. Fernandez, I. Lowy, D. Molrine, et al. “Harmonization of clinical laboratory evaluators' conduct: A Ministry/French Committee for Accreditation (COFRAC) collaboration.” Revue Francophone Des Laboratoires 2010, no. 424 (January 1, 2010): 20–23. https://doi.org/10.1016/s1773-035x(10)70595-5.
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  - Naudin, C., J. Hughes, A. Jefferson, E. Raynaud De Mauverger, G. Fernandez, I. Lowy, D. Molrine, et al. “Accreditation: What you want to know - Abusus non tollit usum. An interview with Hélène Mehay (head of the human health section/COFRAC).” Revue Francophone Des Laboratoires 2010, no. 424 (January 1, 2010): 8–9. https://doi.org/10.1016/S1773-035X(10)70579-7.
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  - Hon, Yuen Yi, Christine E. Chamberlain, David E. Kleiner, Michael S. Ring, Douglas A. Hale, Allan D. Kirk, and Roslyn B. Mannon. “Evaluation of tacrolimus abbreviated area-under-the-curve monitoring in renal transplant patients who are potentially at risk for adverse events.” Clin Transplant 24, no. 4 (2010): 557–63. https://doi.org/10.1111/j.1399-0012.2009.01143.x.
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  - Page, Andrew J., Mandy L. Ford, and Allan D. Kirk. “Memory T-cell-specific therapeutics in organ transplantation.” Curr Opin Organ Transplant 14, no. 6 (December 2009): 643–49. https://doi.org/10.1097/MOT.0b013e328332bd4a.
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  - Neujahr, David C., Adriana C. Cardona, Onome Ulukpo, Mark Rigby, Andres Pelaez, Allan Ramirez, Anthony A. Gal, et al. “Dynamics of human regulatory T cells in lung lavages of lung transplant recipients.” Transplantation 88, no. 4 (August 27, 2009): 521–27. https://doi.org/10.1097/TP.0b013e3181b0e719.
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  - Weaver, Tim A., Ali H. Charafeddine, Avinash Agarwal, Alexandra P. Turner, Maria Russell, Frank V. Leopardi, Robert L. Kampen, et al. “Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates.” Nat Med 15, no. 7 (July 2009): 746–49. https://doi.org/10.1038/nm.1993.
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  - Singh, Kimberly A., Robert L. Kampen, Steven C. Hoffmann, Shady M. Eldaif, and Allan D. Kirk. “Renal epithelial cell-derived monocyte colony stimulating factor as a local informant of renal injury and means of monocyte activation.” Transpl Int 22, no. 7 (July 2009): 730–37. https://doi.org/10.1111/j.1432-2277.2009.00840.x.
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  - Dalakas, Marinos C., Goran Rakocevic, Jens Schmidt, Mohammad Salajegheh, Beverly McElroy, Michael O. Harris-Love, Joseph A. Shrader, et al. “Effect of Alemtuzumab (CAMPATH 1-H) in patients with inclusion-body myositis.” Brain 132, no. Pt 6 (June 2009): 1536–44. https://doi.org/10.1093/brain/awp104.
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  - Ford, Mandy L., Allan D. Kirk, and Christian P. Larsen. “Donor-reactive T-cell stimulation history and precursor frequency: barriers to tolerance induction.” Transplantation 87, no. 9 Suppl (May 15, 2009): S69–74. https://doi.org/10.1097/TP.0b013e3181a2a701.
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  - Gorbach, Alexander M., David B. Leeser, Hengliang Wang, Douglas K. Tadaki, Carlos Fernandez, David Destephano, Douglas Hale, Allan D. Kirk, Fred A. Gage, and Eric A. Elster. “Assessment of cadaveric organ viability during pulsatile perfusion using infrared imaging.” Transplantation 87, no. 8 (April 27, 2009): 1163–66. https://doi.org/10.1097/TP.0b013e31819e3e02.
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  - Kirk, Allan D. “Clinical tolerance 2008.” Transplantation 87, no. 7 (April 15, 2009): 953–55. https://doi.org/10.1097/TP.0b013e31819d415e.
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  - Coley, Shana M., Mandy L. Ford, Samantha C. Hanna, Maylene E. Wagener, Allan D. Kirk, and Christian P. Larsen. “IFN-gamma dictates allograft fate via opposing effects on the graft and on recipient CD8 T cell responses.” J Immunol 182, no. 1 (January 1, 2009): 225–33. https://doi.org/10.4049/jimmunol.182.1.225.
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  - Dhanireddy, K. K., D. A. Bruno, T. A. Weaver, H. Xu, X. Zhang, F. V. Leopardi, D. A. Hale, and A. D. Kirk. “Portal venous donor-specific transfusion in conjunction with sirolimus prolongs renal allograft survival in nonhuman primates.” Am J Transplant 9, no. 1 (January 2009): 124–31. https://doi.org/10.1111/j.1600-6143.2008.02448.x.
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  - Kirk, A. D., C. N. Morrell, and W. M. Baldwin. “Platelets influence vascularized organ transplants from start to finish.” Am J Transplant 9, no. 1 (January 2009): 14–22. https://doi.org/10.1111/j.1600-6143.2008.02473.x.
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  - Turgeon, Nicole A., Allan D. Kirk, and Neal N. Iwakoshi. “Differential effects of donor-specific alloantibody.” Transplant Rev (Orlando) 23, no. 1 (January 2009): 25–33. https://doi.org/10.1016/j.trre.2008.08.001.
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  - Agarwal, Avinash, Luke Y. Shen, and Allan D. Kirk. “The role of alemtuzumab in facilitating maintenance immunosuppression minimization following solid organ transplantation.” Transpl Immunol 20, no. 1–2 (November 2008): 6–11. https://doi.org/10.1016/j.trim.2008.09.003.
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  - Koehn, Brent H., Mandy L. Ford, Ivana R. Ferrer, Keshawna Borom, Shivaprakash Gangappa, Allan D. Kirk, and Christian P. Larsen. “PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue.” J Immunol 181, no. 8 (October 15, 2008): 5313–22. https://doi.org/10.4049/jimmunol.181.8.5313.
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  - Gorbach, Alexander M., Hengliang Wang, Nadeem N. Dhanani, Fred A. Gage, Peter A. Pinto, Paul D. Smith, Allan D. Kirk, and Eric A. Elster. “Assessment of critical renal ischemia with real-time infrared imaging.” J Surg Res 149, no. 2 (October 2008): 310–18. https://doi.org/10.1016/j.jss.2008.02.007.
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  - Vincenti, F., and A. D. Kirk. “What's next in the pipeline.” Am J Transplant 8, no. 10 (October 2008): 1972–81. https://doi.org/10.1111/j.1600-6143.2008.02403.x.
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  - Cendales, L. C., J. Kanitakis, S. Schneeberger, C. Burns, P. Ruiz, L. Landin, M. Remmelink, et al. “The Banff 2007 working classification of skin-containing composite tissue allograft pathology.” Am J Transplant 8, no. 7 (July 2008): 1396–1400. https://doi.org/10.1111/j.1600-6143.2008.02243.x.
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  - Chamberlain, C. E., S. R. Penzak, R. M. Alfaro, R. Wesley, C. E. Daniels, D. Hale, A. D. Kirk, and R. B. Mannon. “Pharmacokinetics of low and maintenance dose valganciclovir in kidney transplant recipients.” Am J Transplant 8, no. 6 (June 2008): 1297–1302. https://doi.org/10.1111/j.1600-6143.2008.02220.x.
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  - Ford, Mandy L., Maylene E. Wagener, Samantha S. Hanna, Thomas C. Pearson, Allan D. Kirk, and Christian P. Larsen. “A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection.” J Immunol 180, no. 11 (June 1, 2008): 7203–11. https://doi.org/10.4049/jimmunol.180.11.7203.
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  - Hanna, Barbara V., Alexander M. Gorbach, Frederic A. Gage, Peter A. Pinto, John S. Silva, Lynne G. Gilfillan, Allan D. Kirk, and Eric A. Elster. “Intraoperative assessment of critical biliary structures with visible range/infrared image fusion.” J Am Coll Surg 206, no. 6 (June 2008): 1227–31. https://doi.org/10.1016/j.jamcollsurg.2007.10.012.
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  - Crane, Nicole J., Peter A. Pinto, Douglas Hale, Frederick A. Gage, Doug Tadaki, Allan D. Kirk, Ira W. Levin, and Eric A. Elster. “Non-invasive monitoring of tissue oxygenation during laparoscopic donor nephrectomy.” Bmc Surg 8 (April 17, 2008): 8. https://doi.org/10.1186/1471-2482-8-8.
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  - Girlanda, R., D. E. Kleiner, Z. Duan, E. A. S. Ford, E. C. Wright, R. B. Mannon, and A. D. Kirk. “Monocyte infiltration and kidney allograft dysfunction during acute rejection.” Am J Transplant 8, no. 3 (March 2008): 600–607. https://doi.org/10.1111/j.1600-6143.2007.02109.x.
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  - Weaver, Timothy A., Ali H. Charafeddine, and Allan D. Kirk. “Costimulation blockade: towards clinical application.” Front Biosci 13 (January 1, 2008): 2120–39. https://doi.org/10.2741/2829.
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  - Elster, Eric A., David B. Leeser, Craig Morrissette, Joseph M. Pepek, Albin Quiko, Douglas A. Hale, Christine Chamberlain, Christine Salaita, Allan D. Kirk, and Roslyn B. Mannon. “Obesity following kidney transplantation and steroid avoidance immunosuppression.” Clin Transplant 22, no. 3 (2008): 354–59. https://doi.org/10.1111/j.1399-0012.2008.00792.x.
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  - Weaver, Timothy A., and Allan D. Kirk. “Alemtuzumab.” Transplantation 84, no. 12 (December 27, 2007): 1545–47. https://doi.org/10.1097/01.tp.0000296680.75175.67.
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  - Kirk, A. D., W. S. Cherikh, M. Ring, G. Burke, D. Kaufman, S. J. Knechtle, S. Potdar, R. Shapiro, V. R. Dharnidharka, and H. M. Kauffman. “Dissociation of depletional induction and posttransplant lymphoproliferative disease in kidney recipients treated with alemtuzumab.” Am J Transplant 7, no. 11 (November 2007): 2619–25. https://doi.org/10.1111/j.1600-6143.2007.01972.x.
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  - Girlanda, Raffaele, and Allan D. Kirk. “Frontiers in nephrology: immune tolerance to allografts in humans.” J Am Soc Nephrol 18, no. 8 (August 2007): 2242–51. https://doi.org/10.1681/ASN.2007020180.
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  - Girlanda, Raffaele, Roslyn B. Mannon, and Allan D. Kirk. “Diagnostic tools for monitoring kidney transplant recipients.” Semin Nephrol 27, no. 4 (July 2007): 462–78. https://doi.org/10.1016/j.semnephrol.2007.03.007.
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  - Kirk, A. D., W. M. Baldwin, M. I. Cascalho, A. S. Chong, M. Sykes, and L. J. West. “American society of transplantation symposium on B cells in transplantation: harnessing humoral immunity from rodent models to clinical practice.” Am J Transplant 7, no. 6 (June 2007): 1464–70. https://doi.org/10.1111/j.1600-6143.2007.01815.x.
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  - Pearl, Jonathan P., He Xu, Frank Leopardi, Edwin Preston, and Allan D. Kirk. “CD154 blockade, sirolimus, and donor-specific transfusion prevents renal allograft rejection in cynomolgus monkeys despite homeostatic T-cell activation.” Transplantation 83, no. 9 (May 15, 2007): 1219–25. https://doi.org/10.1097/01.tp.0000259929.04596.d5.
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  - Mengel, M., J. R. Chapman, F. G. Cosio, M. W. Cavaillé-Coll, H. Haller, P. F. Halloran, A. D. Kirk, et al. “Protocol biopsies in renal transplantation: insights into patient management and pathogenesis.” Am J Transplant 7, no. 3 (March 2007): 512–17. https://doi.org/10.1111/j.1600-6143.2006.01677.x.
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  - Kirk, Allan D. “Induction immunosuppression.” Transplantation 82, no. 5 (September 15, 2006): 593–602. https://doi.org/10.1097/01.tp.0000234905.56926.7f.
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  - Kaplan, B., and A. D. Kirk. “Tacrolimus and sirolimus: when bad things happen to good drugs.” Am J Transplant 6, no. 7 (July 2006): 1501–2. https://doi.org/10.1111/j.1600-6143.2006.01392.x.
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  - Kirk, A. D., D. A. Hale, S. J. Swanson, and R. B. Mannon. “Autoimmune thyroid disease after renal transplantation using depletional induction with alemtuzumab.” Am J Transplant 6, no. 5 Pt 1 (May 2006): 1084–85. https://doi.org/10.1111/j.1600-6143.2006.01258.x.
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  - Larsen, C. P., S. J. Knechtle, A. Adams, T. Pearson, and A. D. Kirk. “A new look at blockade of T-cell costimulation: a therapeutic strategy for long-term maintenance immunosuppression.” Am J Transplant 6, no. 5 Pt 1 (May 2006): 876–83. https://doi.org/10.1111/j.1600-6143.2006.01259.x.
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  - Mannon, Roslyn B., and Allan D. Kirk. “Beyond histology: novel tools to diagnose allograft dysfunction.” Clin J Am Soc Nephrol 1, no. 3 (May 2006): 358–66. https://doi.org/10.2215/CJN.01681105.
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  - Bolanowski, A., R. B. Mannon, S. M. Holland, H. L. Malech, J. Aschan, J. Palmblad, D. A. Hale, and A. D. Kirk. “Successful renal transplantation in patients with chronic granulomatous disease.” Am J Transplant 6, no. 3 (March 2006): 636–39. https://doi.org/10.1111/j.1600-6143.2006.01232.x.
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  - Xu, He, Xiaojie Zhang, Roslyn B. Mannon, and Allan D. Kirk. “Platelet-derived or soluble CD154 induces vascularized allograft rejection independent of cell-bound CD154.” J Clin Invest 116, no. 3 (March 2006): 769–74. https://doi.org/10.1172/JCI27155.
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  - Cendales, Linda C., Allan D. Kirk, J Margaret Moresi, Phillip Ruiz, and David E. Kleiner. “Composite tissue allotransplantation: classification of clinical acute skin rejection.” Transplantation 81, no. 3 (February 15, 2006): 418–22. https://doi.org/10.1097/01.tp.0000185304.49987.d8.
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  - Newell, Kenneth A., Christian P. Larsen, and Allan D. Kirk. “Transplant tolerance: converging on a moving target.” Transplantation 81, no. 1 (January 15, 2006): 1–6. https://doi.org/10.1097/01.tp.0000179149.12979.13.
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  - Xu, He, Kiran K. Dhanireddy, and Allan D. Kirk. “Human monocytes as intermediaries between allogeneic endothelial cells and allospecific T cells: a role for direct scavenger receptor-mediated endothelial membrane uptake in the initiation of alloimmunity.” J Immunol 176, no. 2 (January 15, 2006): 750–61. https://doi.org/10.4049/jimmunol.176.2.750.
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  - Cendales, Linda C., Allan D. Kirk, J Margaret Moresi, Phillip Ruiz, and David E. Kleiner. “Composite tissue allotransplantation: classification of clinical acute skin rejection.” Transplantation 80, no. 12 (December 27, 2005): 1676–80.
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  - Bruno, David A., Kiran K. Dhanireddy, and Allan D. Kirk. “Challenges in therapeutic strategies for transplantation: where now from here?” Transpl Immunol 15, no. 2 (December 2005): 149–55. https://doi.org/10.1016/j.trim.2005.07.001.
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  - Mannon, R. B., S. C. Hoffmann, R. L. Kampen, O. C. Cheng, D. E. Kleiner, C. Ryschkewitsch, B. Curfman, E. Major, D. A. Hale, and A. D. Kirk. “Molecular evaluation of BK polyomavirus nephropathy.” Am J Transplant 5, no. 12 (December 2005): 2883–93. https://doi.org/10.1111/j.1600-6143.2005.01096.x.
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  - Cendales, Linda C., He Xu, John Bacher, Michael A. Eckhaus, David E. Kleiner, and Allan D. Kirk. “Composite tissue allotransplantation: development of a preclinical model in nonhuman primates.” Transplantation 80, no. 10 (November 27, 2005): 1447–54. https://doi.org/10.1097/01.tp.0000183292.57349.27.
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  - Kirk, Allan D., Roslyn B. Mannon, David E. Kleiner, John S. Swanson, Robert L. Kampen, Linda K. Cendales, Eric A. Elster, et al. “Results from a human renal allograft tolerance trial evaluating T-cell depletion with alemtuzumab combined with deoxyspergualin.” Transplantation 80, no. 8 (October 27, 2005): 1051–59. https://doi.org/10.1097/01.tp.0000174341.49741.8f.
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  - Hale, Douglas A., Kiran Dhanireddy, David Bruno, and Allan D. Kirk. “Induction of transplantation tolerance in non-human primate preclinical models.” Philos Trans R Soc Lond B Biol Sci 360, no. 1461 (September 29, 2005): 1723–37. https://doi.org/10.1098/rstb.2005.1703.
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  - Chamberlain, Christine E., Edmond Fitzgibbon, Eric M. Wassermann, John A. Butman, David Kettl, Doug Hale, Allan D. Kirk, and Roslyn B. Mannon. “Idiopathic intracranial hypertension following kidney transplantation: a case report and review of the literature.” Pediatr Transplant 9, no. 4 (August 2005): 545–50. https://doi.org/10.1111/j.1399-3046.2005.00329.x.
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  - Meyers, Catherine M., and Allan D. Kirk. “Workshop on late renal allograft dysfunction.” Am J Transplant 5, no. 7 (July 2005): 1600–1605. https://doi.org/10.1111/j.1600-6143.2005.00926.x.
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  - Dhanireddy, Kiran K., Jennifer Maniscalco, and Allan D. Kirk. “Is tolerance induction the answer to adolescent non-adherence?” Pediatr Transplant 9, no. 3 (June 2005): 357–63. https://doi.org/10.1111/j.1399-3046.2005.00285.x.
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  - Preston, Edwin H., He Xu, Kiran K. Dhanireddy, Jonathan P. Pearl, Frank V. Leopardi, Matthew F. Starost, Douglas A. Hale, and Allan D. Kirk. “IDEC-131 (anti-CD154), sirolimus and donor-specific transfusion facilitate operational tolerance in non-human primates.” Am J Transplant 5, no. 5 (May 2005): 1032–41. https://doi.org/10.1111/j.1600-6143.2005.00796.x.
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  - Bromberg, Jonathan S., Jeffrey H. Silverstein, and Allan D. Kirk. “Proposal for the American Journal of Transplantation policy for review of ethical standards of clinical research involving live human subjects.” Am J Transplant 5, no. 4 Pt 1 (April 2005): 648–50. https://doi.org/10.1111/j.1600-6143.2005.00872.x.
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  - Elster, Eric A., Douglas A. Hale, Roslyn B. Mannon, Linda C. Cendales, David Kleiner, S John Swanson, and Allan D. Kirk. “Surgical transplant physical examination: correlation of renal resistance index and biopsy-proven chronic allograft nephropathy.” J Am Coll Surg 200, no. 4 (April 2005): 552–56. https://doi.org/10.1016/j.jamcollsurg.2004.12.009.
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  - Hoffmann, Steven C., Douglas A. Hale, David E. Kleiner, Roslyn B. Mannon, Robert L. Kampen, Lynn M. Jacobson, Linda C. Cendales, S John Swanson, Bryan N. Becker, and Allan D. Kirk. “Functionally significant renal allograft rejection is defined by transcriptional criteria.” Am J Transplant 5, no. 3 (March 2005): 573–81. https://doi.org/10.1111/j.1600-6143.2005.00719.x.
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  - Pearl, Jonathan P., Jeremy Parris, Douglas A. Hale, Steven C. Hoffmann, Wendy B. Bernstein, Kelly L. McCoy, S John Swanson, Roslyn B. Mannon, Mario Roederer, and Allan D. Kirk. “Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion.” Am J Transplant 5, no. 3 (March 2005): 465–74. https://doi.org/10.1111/j.1600-6143.2005.00759.x.
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  - Czapiga, Meggan, Ji-Liang Gao, Allan Kirk, and Julie Lekstrom-Himes. “Human platelets exhibit chemotaxis using functional N-formyl peptide receptors.” Exp Hematol 33, no. 1 (January 2005): 73–84. https://doi.org/10.1016/j.exphem.2004.09.010.
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  - Kirk, Allan D., Roslyn B. Mannon, S John Swanson, and Douglas A. Hale. “Strategies for minimizing immunosuppression in kidney transplantation.” Transpl Int 18, no. 1 (January 2005): 2–14. https://doi.org/10.1111/j.1432-2277.2004.00019.x.
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  - Ferrant, Janine L., Christopher D. Benjamin, Anne H. Cutler, Susan L. Kalled, Yen-Ming Hsu, Ellen A. Garber, Donna M. Hess, et al. “The contribution of Fc effector mechanisms in the efficacy of anti-CD154 immunotherapy depends on the nature of the immune challenge.” Int Immunol 16, no. 11 (November 2004): 1583–94. https://doi.org/10.1093/intimm/dxh162.
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  - Kirk, Allan D. “What's new--what's hot in basic science: American Transplant Congress 2004.” Am J Transplant 4, no. 11 (November 2004): 1741–46. https://doi.org/10.1111/j.1600-6143.2004.00632.x.
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  - Hoffmann, Steven, Jenny Park, Lynn M. Jacobson, Rebecca J. Muehrer, David Lorentzen, David Kleiner, Yolanda T. Becker, et al. “Donor genomics influence graft events: the effect of donor polymorphisms on acute rejection and chronic allograft nephropathy.” Kidney Int 66, no. 4 (October 2004): 1686–93. https://doi.org/10.1111/j.1523-1755.2004.00936.x.
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  - Dhanireddy, Kiran K., He Xu, Roslyn B. Mannon, Douglas A. Hale, and Allan D. Kirk. “The clinical application of monoclonal antibody therapies in renal transplantation.” Expert Opin Emerg Drugs 9, no. 1 (May 2004): 23–37. https://doi.org/10.1517/eoed.9.1.23.32957.
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  - Kirk, Allan D. “Ethics in the quest for transplant tolerance.” Transplantation 77, no. 6 (March 27, 2004): 947–51. https://doi.org/10.1097/01.tp.0000117778.83216.29.
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  - McNally, Michael, Roslyn B. Mannon, Edward D. Javor, S John Swanson, Douglas A. Hale, Phillip Gorden, and Allan D. Kirk. “Successful renal transplantation in a patient with congenital generalized lipodystrophy: a case report.” Am J Transplant 4, no. 3 (March 2004): 447–49. https://doi.org/10.1111/j.1600-6143.2004.00358.x.
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  - Czapiga, Meggan, Allan D. Kirk, and Julie Lekstrom-Himes. “Platelets deliver costimulatory signals to antigen-presenting cells: a potential bridge between injury and immune activation.” Exp Hematol 32, no. 2 (February 2004): 135–39. https://doi.org/10.1016/j.exphem.2003.11.004.
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  - Preston, Edwin H., Jimmy A. Light, Robert L. Kampen, and Allan D. Kirk. “Human renal allograft rejection despite the absence of allogeneic passenger leukocytes.” Am J Transplant 4, no. 2 (February 2004): 283–85. https://doi.org/10.1046/j.1600-6143.2003.00320.x.
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  - Hale, D. A., and A. D. Kirk. “Mammalian target of rapamycin inhibitors in transplantation: Novel immunosuppressive strategies with sirolimus.” Current Opinion in Organ Transplantation 9, no. 4 (2004): 400–405. https://doi.org/10.1097/01.mot.0000145087.34739.14.
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  - Elster, Eric A., Douglas A. Hale, Roslyn B. Mannon, Linda C. Cendales, S John Swanson, and Allan D. Kirk. “The road to tolerance: renal transplant tolerance induction in nonhuman primate studies and clinical trials.” Transpl Immunol 13, no. 2 (2004): 87–99. https://doi.org/10.1016/j.trim.2004.05.010.
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  - Kirk, Allan D. “Crossing the bridge: large animal models in translational transplantation research.” Immunol Rev 196 (December 2003): 176–96. https://doi.org/10.1046/j.1600-065x.2003.00081.x.
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  - Pearl, Jonathan P., Edwin Preston, and Allan D. Kirk. “Tolerance: is it achievable in pediatric solid organ transplantation?” Pediatr Clin North Am 50, no. 6 (December 2003): 1261–vii. https://doi.org/10.1016/s0031-3955(03)00120-2.
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  - Xu, He, Eric A. Elster, Patrick J. Blair, Linda C. Burkly, Douglas K. Tadaki, David M. Harlan, and Allan D. Kirk. “Effects of combined treatment with CD25- and CD154-specific monoclonal antibodies in non-human primate allotransplantation.” Am J Transplant 3, no. 11 (November 2003): 1350–54. https://doi.org/10.1046/j.1600-6135.2003.00235.x.
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  - Hoffmann, Steven C., Jonathan P. Pearl, Patrick J. Blair, and Allan D. Kirk. “Immune profiling: molecular monitoring in renal transplantation.” Front Biosci 8 (September 1, 2003): e444–62. https://doi.org/10.2741/1167.
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  - Gorbach, Alexander, Donna Simonton, Douglas A. Hale, S John Swanson, and Allan D. Kirk. “Objective, real-time, intraoperative assessment of renal perfusion using infrared imaging.” Am J Transplant 3, no. 8 (August 2003): 988–93. https://doi.org/10.1034/j.1600-6143.2003.00158.x.
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  - Hirshberg, Boaz, Edwin H. Preston, He Xu, Michel G. Tal, Ziv Neeman, David Bunnell, Scott Soleimanpour, Douglas A. Hale, Allan D. Kirk, and David M. Harlan. “Rabbit antithymocyte globulin induction and sirolimus monotherapy supports prolonged islet allograft function in a nonhuman primate islet transplantation model.” Transplantation 76, no. 1 (July 15, 2003): 55–60. https://doi.org/10.1097/01.TP.0000068899.48252.1D.
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  - Kirk, Allan D., Douglas A. Hale, Roslyn B. Mannon, David E. Kleiner, Steven C. Hoffmann, Robert L. Kampen, Linda K. Cendales, Douglas K. Tadaki, David M. Harlan, and S John Swanson. “Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H).” Transplantation 76, no. 1 (July 15, 2003): 120–29. https://doi.org/10.1097/01.TP.0000071362.99021.D9.
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  - Tadaki, D. K., A. Williams, K. P. Lee, A. D. Kirk, and D. M. Harlan. “Porcine CD80: cloning, characterization, and evidence for its role in direct human T-cell activation.” Xenotransplantation 10, no. 3 (May 2003): 252–58. https://doi.org/10.1034/j.1399-3089.2003.02004.x.
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  - Cendales, Linda C., S John Swanson, Allan D. Kirk, Roslyn B. Mannon, and Douglas A. Hale. “Delayed autotransplantation of a solitary kidney facilitated by pump perfusion preservation.” Surgery 133, no. 4 (April 2003): 438–39. https://doi.org/10.1067/msy.2003.129.
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  - Vanrenterghem, Yves, Kathleen Claes, Pieter Evenepoel, Dirk Kuypers, and Bart Maes. “Kidney transplantation with rabbit antithymocyte globulin and sirolimus monotherapy.” The Lancet 361, no. 9361 (March 2003): 969–969. https://doi.org/10.1016/s0140-6736(03)12752-3.
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  - Xu, He, Sean P. Montgomery, Edwin H. Preston, Douglas K. Tadaki, Douglas A. Hale, David M. Harlan, and Allan D. Kirk. “Studies investigating pretransplant donor-specific blood transfusion, rapamycin, and the CD154-specific antibody IDEC-131 in a nonhuman primate model of skin allotransplantation.” J Immunol 170, no. 5 (March 1, 2003): 2776–82. https://doi.org/10.4049/jimmunol.170.5.2776.
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  - Hale, D. A., S. J. Swanson, R. B. Mannon, D. E. Kleiner, S. C. Hoffmann, R. L. Kampen, L. K. Cendales, D. K. Tadaki, D. M. Harlan, and D. M. et al. “Immunologic monitoring of the transplant recipient: Challenges and approaches with antibody induction.” Transplantation Reviews 17, no. 4 SUPPL. (2003): S20–25. https://doi.org/10.1016/j.trre.2003.07.003.
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  - Li, Rui-Mei, Roslyn B. Mannon, David Kleiner, Maria Tsokos, Michelle Bynum, Allen D. Kirk, and Jeffrey B. Kopp. “BK virus and SV40 co-infection in polyomavirus nephropathy.” Transplantation 74, no. 11 (December 15, 2002): 1497–1504. https://doi.org/10.1097/00007890-200212150-00004.
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  - Montgomery, Sean P., He Xu, Douglas K. Tadaki, Abbie Celniker, Linda C. Burkly, Justin D. Berning, Francis Cruzata, et al. “Combination induction therapy with monoclonal antibodies specific for CD80, CD86, and CD154 in nonhuman primate renal transplantation.” Transplantation 74, no. 10 (November 27, 2002): 1365–69. https://doi.org/10.1097/00007890-200211270-00002.
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  - Swanson, S John, Douglas A. Hale, Roslyn B. Mannon, David E. Kleiner, Linda C. Cendales, Christine E. Chamberlain, Shirley M. Polly, David M. Harlan, and Allan D. Kirk. “Kidney transplantation with rabbit antithymocyte globulin induction and sirolimus monotherapy.” Lancet 360, no. 9346 (November 23, 2002): 1662–64. https://doi.org/10.1016/S0140-6736(02)11606-0.
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  - Hoffmann, Steven C., Robert L. Kampen, Shashi Amur, Muhammad A. Sharaf, David E. Kleiner, Keith Hunter, S. John Swanson, et al. “Molecular and immunohistochemical characterization of the onset and resolution of human renal allograft ischemia-reperfusion injury.” Transplantation 74, no. 7 (October 15, 2002): 916–23. https://doi.org/10.1097/00007890-200210150-00003.
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  - Xu, He, Douglas K. Tadaki, Eric A. Elster, Linda C. Burkly, Justin D. Berning, Francis Cruzata, Robert L. Kampen, et al. “Humanized anti-CD154 antibody therapy for the treatment of allograft rejection in nonhuman primates.” Transplantation 74, no. 7 (October 15, 2002): 940–43. https://doi.org/10.1097/00007890-200210150-00007.
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  - Swanson, S. J., A. D. Kirk, C. W. Ko, C. A. Jones, L. Y. Agodoa, and K. C. Abbott. “Impact of HIV seropositivity on graft and patient survival after cadaveric renal transplantation in the United States in the pre highly active antiretroviral therapy (HAART) era: an historical cohort analysis of the United States Renal Data System.” Transpl Infect Dis 4, no. 3 (September 2002): 144–47. https://doi.org/10.1034/j.1399-3062.2002.01009.x.
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  - Hirshberg, Boaz, Sean Montgomery, Michael G. Wysoki, He Xu, Doug Tadaki, Janet Lee, Kenneth Hines, et al. “Pancreatic islet transplantation using the nonhuman primate (rhesus) model predicts that the portal vein is superior to the celiac artery as the islet infusion site.” Diabetes 51, no. 7 (July 2002): 2135–40. https://doi.org/10.2337/diabetes.51.7.2135.
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  - Hoffmann, Steven C., Eran M. Stanley, E Darrin Cox, Barbara S. DiMercurio, Deloris E. Koziol, David M. Harlan, Allan D. Kirk, and Patrick J. Blair. “Ethnicity greatly influences cytokine gene polymorphism distribution.” Am J Transplant 2, no. 6 (July 2002): 560–67. https://doi.org/10.1034/j.1600-6143.2002.20611.x.
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  - Tzakis, A. G., T. Kato, S. Nishida, D. Levi, J. Madariaga, W. De Faria, J. Nery, G. Neff, A. D. Kirk, and P. Ruiz. “Campath-1H in intestinal and multivisceral transplantation: preliminary data.” Transplant Proc 34, no. 3 (May 2002): 937. https://doi.org/10.1016/s0041-1345(02)02679-9.
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  - Montgomery, Sean P., Steven R. Mog, He Xu, Douglas K. Tadaki, Boaz Hirshberg, Justin D. Berning, John Leconte, David M. Harlan, Douglas Hale, and Allan D. Kirk. “Efficacy and toxicity of a protocol using sirolimus, tacrolimus and daclizumab in a nonhuman primate renal allotransplant model.” Am J Transplant 2, no. 4 (April 2002): 381–85. https://doi.org/10.1034/j.1600-6143.2002.20415.x.
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  - Irwin, G., A. D. Kirk, I. Mackay, and J. Nera. “Photochemistry and photophysics of Cr(III) macrocyclic complexes.” Inorg Chem 41, no. 4 (February 25, 2002): 874–83. https://doi.org/10.1021/ic010236j.
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  - Becker, B. N., L. M. Jacobson, D. A. Hullett, N. A. Radke, T. D. Oberley, P. C. Brazy, and A. D. Kirk. “Type 2 angiotensin II receptor expression in human renal allografts: an association with chronic allograft nephropathy.” Clinical Nephrology 57, no. 1 (January 1, 2002): 19–26.
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  - Preston, E., and A. D. Kirk. “Context-based therapy: A conceptual framework for transplantation tolerance.” Transplantation Reviews 16, no. 3 (2002): 142–62.
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  - Becker, B. N., L. M. Jacobson, D. A. Hullett, N. A. Radke, T. D. Oberley, P. C. Brazy, and A. D. Kirk. “Type 2 angiotensin II receptor expression in human renal allografts: an association with chronic allograft nephropathy.” Clin Nephrol 57, no. 1 (January 2002): 19–26. https://doi.org/10.5414/cnp57019.
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  - Swanson, S John, Iman O. Hypolite, Lawrence Y. C. Agodoa, D Scott Batty, Paul B. Hshieh, David Cruess, Allan D. Kirk, Thomas G. Peters, and Kevin C. Abbott. “Effect of donor factors on early graft survival in adult cadaveric renal transplantation.” Am J Transplant 2, no. 1 (January 2002): 68–75. https://doi.org/10.1034/j.1600-6143.2002.020112.x.
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  - Xu, H., F. Arnaud, D. K. Tadaki, L. C. Burkly, D. M. Harlan, and A. D. Kirk. “Human platelets activate porcine endothelial cells through a CD154-dependent pathway.” Transplantation 72, no. 11 (December 15, 2001): 1858–61. https://doi.org/10.1097/00007890-200112150-00029.
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  - Elster, E. A., H. Xu, D. K. Tadaki, S. Montgomery, L. C. Burkly, J. D. Berning, R. E. Baumgartner, et al. “Treatment with the humanized CD154-specific monoclonal antibody, hu5C8, prevents acute rejection of primary skin allografts in nonhuman primates.” Transplantation 72, no. 9 (November 15, 2001): 1473–78. https://doi.org/10.1097/00007890-200111150-00001.
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  - Hoffmann, S. C., E. M. Stanley, E. Darrin Cox, N. Craighead, B. S. DiMercurio, D. E. Koziol, D. M. Harlan, A. D. Kirk, and P. J. Blair. “Association of cytokine polymorphic inheritance and in vitro cytokine production in anti-CD3/CD28-stimulated peripheral blood lymphocytes.” Transplantation 72, no. 8 (October 27, 2001): 1444–50. https://doi.org/10.1097/00007890-200110270-00019.
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  - Abbott, K. C., R. J. Oglesby, I. O. Hypolite, A. D. Kirk, C. W. Ko, P. G. Welch, L. Y. Agodoa, and W. E. Duncan. “Hospitalizations for fractures after renal transplantation in the United States.” Ann Epidemiol 11, no. 7 (October 2001): 450–57. https://doi.org/10.1016/s1047-2797(01)00226-5.
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  - Montgomery, S. P., D. A. Hale, B. Hirshberg, D. M. Harlan, and A. D. Kirk. “Preclinical evaluation of tolerance induction protocols and islet transplantation in non-human primates.” Immunol Rev 183 (October 2001): 214–22. https://doi.org/10.1034/j.1600-065x.2001.1830117.x.
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  - Cho, C. S., L. C. Burkly, J. H. Fechner, A. D. Kirk, T. D. Oberley, Y. Dong, K. G. Brunner, et al. “Successful conversion from conventional immunosuppression to anti-CD154 monoclonal antibody costimulatory molecule blockade in rhesus renal allograft recipients.” Transplantation 72, no. 4 (August 27, 2001): 587–97. https://doi.org/10.1097/00007890-200108270-00006.
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  - Cox, E. D., S. C. Hoffmann, B. S. DiMercurio, R. A. Wesley, D. M. Harlan, A. D. Kirk, and P. J. Blair. “Cytokine polymorphic analyses indicate ethnic differences in the allelic distribution of interleukin-2 and interleukin-6.” Transplantation 72, no. 4 (August 27, 2001): 720–26. https://doi.org/10.1097/00007890-200108270-00027.
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  - Kirk, A. D., D. K. Tadaki, A. Celniker, D. S. Batty, J. D. Berning, J. O. Colonna, F. Cruzata, et al. “Induction therapy with monoclonal antibodies specific for CD80 and CD86 delays the onset of acute renal allograft rejection in non-human primates.” Transplantation 72, no. 3 (August 15, 2001): 377–84. https://doi.org/10.1097/00007890-200108150-00005.
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  - Batty, D. S., S. J. Swanson, A. D. Kirk, C. W. Ko, L. Y. Agodoa, and K. C. Abbott. “Hepatitis C virus seropositivity at the time of renal transplantation in the United States: associated factors and patient survival.” Am J Transplant 1, no. 2 (July 2001): 179–84.
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  - Kirk, A. D., P. J. Blair, D. K. Tadaki, H. Xu, and D. M. Harlan. “The role of CD154 in organ transplant rejection and acceptance.” Philos Trans R Soc Lond B Biol Sci 356, no. 1409 (May 29, 2001): 691–702. https://doi.org/10.1098/rstb.2001.0855.
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  - Abbott, K. C., E. S. Sawyers, J. D. Oliver, C. W. Ko, A. D. Kirk, P. G. Welch, T. G. Peters, and L. Y. Agodoa. “Graft loss due to recurrent focal segmental glomerulosclerosis in renal transplant recipients in the United States.” Am J Kidney Dis 37, no. 2 (February 2001): 366–73. https://doi.org/10.1053/ajkd.2001.21311.
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  - Abbott, K. C., J. D. Oliver, I. Hypolite, L. L. Lepler, A. D. Kirk, C. W. Ko, C. A. Hawkes, C. A. Jones, and L. Y. Agodoa. “Hospitalizations for bacterial septicemia after renal transplantation in the united states.” Am J Nephrol 21, no. 2 (2001): 120–27. https://doi.org/10.1159/000046234.
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  - Elster, E. A., H. Xu, D. K. Tadaki, L. C. Burkly, J. D. Berning, R. E. Baumgartner, F. Cruzata, N. B. Patterson, D. M. Harlan, and A. D. Kirk. “Primate skin allotransplantation with anti-CD154 monotherapy.” Transplant Proc 33, no. 1–2 (2001): 675–76. https://doi.org/10.1016/s0041-1345(00)02197-7.
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  - Irwin, Garth, and Alexander D. Kirk. “Intermediates in chromium(III) photochemistry.” Coordination Chemistry Reviews 211, no. 1 (January 2001): 25–43. https://doi.org/10.1016/s0010-8545(00)00281-2.
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  - Xu, H., E. Elster, D. Batty, J. Berning, L. Burkly, R. Kampen, S. Swanson, D. Tadaki, D. Harlan, and A. Kirk. “Effects of dose and duration of anti-CD154 antibody therapy in preventing renal allograft rejection in a nonhuman primate model.” Transplant Proc 33, no. 1–2 (2001): 223–24. https://doi.org/10.1016/s0041-1345(00)01983-7.
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  - Tadaki, D. K., N. Craighead, A. Saini, A. Celniker, L. C. Burkly, K. P. Lee, J. P. Chute, D. M. Harlan, and A. D. Kirk. “Costimulatory molecules are active in the human xenoreactive T-cell response but not in natural killer-mediated cytotoxicity.” Transplantation 70, no. 1 (July 15, 2000): 162–67.
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  - Harlan, David M., and Allan D. Kirk. “Promise of costimulatory pathway modifying reagents for transplantation.” Current Opinion in Organ Transplantation 5, no. 2 (June 2000): 90–95. https://doi.org/10.1097/00075200-200006000-00009.
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  - Kirk, Allan D. “Convergent theories of transplantation tolerance.” Current Opinion in Organ Transplantation 5, no. 2 (June 2000): 81–82. https://doi.org/10.1097/00075200-200006000-00007.
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  - Kirk, Allan D., and David M. Harlan. “Challenges for the clinical application of transplant tolerance strategies.” Current Opinion in Organ Transplantation 5, no. 2 (June 2000): 108–13. https://doi.org/10.1097/00075200-200006000-00012.
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  - Kirk, A. D., D. K. Tadaki, H. Xu, E. A. Elster, L. C. Burkley, A. Celniker, D. S. Batty, et al. “Primate allotransplantation using costimulation blockade.” Transplantation 69, no. 8 (April 27, 2000): S414–S414.
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  - Becker, B. N., L. M. Jacobson, Y. T. Becker, N. A. Radke, D. M. Heisey, T. D. Oberley, J. D. Pirsch, H. W. Sollinger, P. C. Brazy, and A. D. Kirk. “Renin-angiotensin system gene expression in post-transplant hypertension predicts allograft function.” Transplantation 69, no. 7 (April 15, 2000): 1485–91. https://doi.org/10.1097/00007890-200004150-00046.
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  - Burlingham, W. J., P. J. O’Connell, L. M. Jacobson, B. N. Becker, A. D. Kirk, V. Pravica, and I. V. Hutchinson. “Tumor necrosis factor-alpha and tumor growth factor-beta1 genotype: partial association with intragraft gene expression in two cases of long-term peripheral tolerance to a kidney transplant.” Transplantation 69, no. 7 (April 15, 2000): 1527–30. https://doi.org/10.1097/00007890-200004150-00058.
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  - Rayhill, S. C., A. M. D’Alessandro, J. S. Odorico, S. J. Knechtle, J. D. Pirsch, D. M. Heisey, A. D. Kirk, W. Van der Werf, and H. W. Sollinger. “Simultaneous pancreas-kidney transplantation and living related donor renal transplantation in patients with diabetes: is there a difference in survival?” Ann Surg 231, no. 3 (March 2000): 417–23. https://doi.org/10.1097/00000658-200003000-00015.
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  - Blair, P. J., J. L. Riley, D. M. Harlan, R. Abe, D. K. Tadaki, S. C. Hoffmann, L. White, et al. “CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis.” J Exp Med 191, no. 4 (February 21, 2000): 651–60. https://doi.org/10.1084/jem.191.4.651.
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  - Kirk, Allan D., and David M. Harlan. “Reply to Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand.” Nature Medicine 6, no. 2 (February 2000): 114–114. https://doi.org/10.1038/72164.
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  - Elster, E. A., P. J. Blair, and A. D. Kirk. “Potential of costimulation-based therapies for composite tissue allotransplantation.” Microsurgery 20, no. 8 (2000): 430–34. https://doi.org/10.1002/1098-2752(2000)20:8<430::aid-micr14>3.0.co;2-k.
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  - Kirk, A. D., L. M. Jacobson, D. M. Heisey, N. F. Radke, J. D. Pirsch, and H. W. Sollinger. “Clinically stable human renal allografts contain histological and RNA-based findings that correlate with deteriorating graft function.” Transplantation 68, no. 10 (November 27, 1999): 1578–82. https://doi.org/10.1097/00007890-199911270-00024.
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  - Harlan, D. M., and A. D. Kirk. “The future of organ and tissue transplantation: can T-cell costimulatory pathway modifiers revolutionize the prevention of graft rejection?” Jama 282, no. 11 (September 15, 1999): 1076–82. https://doi.org/10.1001/jama.282.11.1076.
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  - Kenyon, N. S., M. Chatzipetrou, M. Masetti, A. Ranuncoli, M. Oliveira, J. L. Wagner, A. D. Kirk, D. M. Harlan, L. C. Burkly, and C. Ricordi. “Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154.” Proc Natl Acad Sci U S A 96, no. 14 (July 6, 1999): 8132–37. https://doi.org/10.1073/pnas.96.14.8132.
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  - Kenyon, N. S., L. A. Fernandez, R. Lehmann, M. Masetti, A. Ranuncoli, M. Chatzipetrou, G. Iaria, et al. “Long-term survival and function of intrahepatic islet allografts in baboons treated with humanized anti-CD154.” Diabetes 48, no. 7 (July 1999): 1473–81. https://doi.org/10.2337/diabetes.48.7.1473.
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  - Kirk, A. D., L. C. Burkly, D. S. Batty, R. E. Baumgartner, J. D. Berning, K. Buchanan, J. H. Fechner, et al. “Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates.” Nat Med 5, no. 6 (June 1999): 686–93. https://doi.org/10.1038/9536.
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  - Knechtle, S. J., A. D. Kirk, J. H. Fechner, X. Hong, Y. Dong, M. M. Hamawy, and D. M. Harlan. “Inducing unresponsiveness by the use of anti-CD3 immunotoxin, CTLA4-Ig, and anti-CD40 ligand.” Transplant Proc 31, no. 3B Suppl (May 1999): 27S-28S. https://doi.org/10.1016/s0041-1345(99)00100-1.
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  - Kirk, A. D. “Immunosuppression without immunosuppression? How to be a tolerant individual in a dangerous world.” Transpl Infect Dis 1, no. 1 (March 1999): 65–75. https://doi.org/10.1034/j.1399-3062.1999.10107.x.
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  - Burlingham, W., S. Kusaka, L. Chin, D. Hullett, S. Knechtle, H. Sollinger, T. Oberley, J. Pirsch, A. D. Kirk, and B. N. Becker. “Focal infiltrates in kidney allografts: developing a model for clinical transplant peripheral tolerance.” Graft 2 (1999): 253–60.
  - Elster, E. A., R. L. Kampen, K. A. Robson, D. K. Tadaki, P. Perdue, R. M. McCarron, and A. D. Kirk. “Apoptosis regulatory genes BCL-2 and BAX are induced immediately following ischemic/reperfusion injury.” Surgical Forum 50 (1999): 383–84.
  - Kirk, A. D. “Transplantation tolerance: a look at the nonhuman primate literature in the light of modern tolerance theories.” Crit Rev Immunol 19, no. 5–6 (1999): 349–88.
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  - Armstrong, N., P. Buckley, T. Oberley, J. Fechner, Y. Dong, X. Hong, A. Kirk, D. Neville, and S. Knechtle. “Analysis of primate renal allografts after T-cell depletion with anti-CD3-CRM9.” Transplantation 66, no. 1 (July 15, 1998): 5–13. https://doi.org/10.1097/00007890-199807150-00002.
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  - Harlan, D. M., and A. D. Kirk. “Anti-CD154 therapy to prevent graft rejection.” Graft 1 (1998): 63–63.
  - Van der Werf, W. J., A. M. D’Alessandro, S. J. Knechtle, G. Pilli, R. M. Hoffmann, R. H. Judd, J. S. Odorico, et al. “Infant pediatric liver transplantation results equal those for older pediatric patients.” J Pediatr Surg 33, no. 1 (January 1998): 20–23. https://doi.org/10.1016/s0022-3468(98)90353-0.
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  - Kirk, A. D., L. M. Jacobson, D. M. Heisey, N. A. Fass, H. W. Sollinger, and J. D. Pirsch. “Posttransplant diastolic hypertension: associations with intragraft transforming growth factor-beta, endothelin, and renin transcription.” Transplantation 64, no. 12 (December 27, 1997): 1716–20. https://doi.org/10.1097/00007890-199712270-00015.
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  - Kirk, A. D., D. M. Harlan, N. N. Armstrong, T. A. Davis, Y. Dong, G. S. Gray, X. Hong, D. Thomas, J. H. Fechner, and S. J. Knechtle. “CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates.” Proc Natl Acad Sci U S A 94, no. 16 (August 5, 1997): 8789–94. https://doi.org/10.1073/pnas.94.16.8789.
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  - Jerome, K. R., A. D. Kirk, G. Pecher, W. W. Ferguson, and O. J. Finn. “A survivor of breast cancer with immunity to MUC-1 mucin, and lactational mastitis.” Cancer Immunol Immunother 43, no. 6 (January 1997): 355–60. https://doi.org/10.1007/s002620050344.
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  - Kirk, A. D., D. M. Heisey, A. M. D’Alessandro, S. J. Knechtle, J. S. Odorico, S. C. Rayhill, H. W. Sollinger, and J. D. Pirsch. “Clinical hepatitis after transplantation of hepatitis C virus-positive kidneys: HLA-DR3 as a risk factor for the development of posttransplant hepatitis.” Transplantation 62, no. 12 (December 27, 1996): 1758–62. https://doi.org/10.1097/00007890-199612270-00011.
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  - Ibrahim, S., A. D. Kirk, and F. Sanfilippo. “Phenotype of infiltrating cells in an ex vivo model of human antiporcine hyperacute cardiac xenograft rejection.” Transplant Proc 28, no. 2 (April 1996): 777.
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  - Rayhill, S. C., M. Heimes, A. D. Kirk, and H. W. Sollinger. “Simultaneous pancreas - kidney transplantation: Recent experience at the University of Wisconsin.” Experimental and Clinical Endocrinology and Diabetes 104, no. 5 (1996): 353–59.
  - Kirk, A. D., R. R. Bollinger, and O. J. Finn. “Rapid, comprehensive analysis of human cytokine mRNA and its application to the study of acute renal allograft rejection.” Hum Immunol 43, no. 2 (June 1995): 113–28. https://doi.org/10.1016/0198-8859(94)00158-m.
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  - Rayhill, S. C., A. D. Kirk, J. S. Odorico, D. M. Heisey, C. B. Cangro, J. D. Pirsch, A. M. D’Alessandro, S. J. Knechtle, and H. W. Sollinger. “Simultaneous pancreas-kidney transplantation at the University of Wisconsin.” Clin Transpl, 1995, 261–69.
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  - Chari, R. S., B. H. Collins, J. C. Magee, J. M. DiMaio, A. D. Kirk, R. C. Harland, R. L. McCann, J. L. Platt, and W. C. Meyers. “Brief report: treatment of hepatic failure with ex vivo pig-liver perfusion followed by liver transplantation.” N Engl J Med 331, no. 4 (July 28, 1994): 234–37. https://doi.org/10.1056/NEJM199407283310404.
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  - Pruitt, S. K., A. D. Kirk, R. R. Bollinger, H. C. Marsh, B. H. Collins, J. L. Levin, J. R. Mault, J. S. Heinle, S. Ibrahim, and A. R. Rudolph. “The effect of soluble complement receptor type 1 on hyperacute rejection of porcine xenografts.” Transplantation 57, no. 3 (February 1994): 363–70. https://doi.org/10.1097/00007890-199402150-00009.
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  - Kirk, A. D., J. S. Heinle, J. R. Mault, and F. Sanfilippo. “Ex vivo characterization of human anti-porcine hyperacute cardiac rejection.” Transplantation 56, no. 4 (October 1993): 785–93. https://doi.org/10.1097/00007890-199310000-00003.
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  - Ross, J. R., A. D. Kirk, S. E. Ibrahim, D. N. Howell, W. M. Baldwin, and F. P. Sanfilippo. “Characterization of human anti-porcine "natural antibodies" recovered from ex vivo perfused hearts--predominance of IgM and IgG2.” Transplantation 55, no. 5 (May 1993): 1144–50. https://doi.org/10.1097/00007890-199305000-00040.
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  - Kirk, A. D., R. A. Li, M. S. Kinch, K. A. Abernethy, C. Doyle, and R. R. Bollinger. “The human antiporcine cellular repertoire. In vitro studies of acquired and innate cellular responsiveness.” Transplantation 55, no. 4 (April 1993): 924–31.
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  - Li, R. A., A. D. Kirk, K. A. Abernathy, and R. R. Bollinger. “Human antiporcine mixed lymphocyte reaction.” Transplant Proc 25, no. 1 Pt 1 (February 1993): 442–43.
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  - Kirk, A. D., S. Ibrahim, D. V. Dawson, F. Sanfilippo, and O. J. Finn. “Characterization of T cells expressing the gamma/delta antigen receptor in human renal allografts.” Hum Immunol 36, no. 1 (January 1993): 11–19. https://doi.org/10.1016/0198-8859(93)90003-j.
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  - Hall, B. L., S. L. Hand, M. D. Alter, A. D. Kirk, and O. J. Finn. “Variables affecting the T cell receptor V beta repertoire heterogeneity of T cells infiltrating human renal allografts.” Transpl Immunol 1, no. 3 (1993): 217–27. https://doi.org/10.1016/0966-3274(93)90050-i.
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  - Kirk, A. D., B. L. Hall, O. J. Finn, and R. R. Bollinger. “In vitro analysis of the human antiporcine T-cell repertoire.” Transplant Proc 24, no. 2 (April 1992): 602–3.
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  - Kirk, A. D., M. A. Ibrahim, R. R. Bollinger, D. V. Dawson, and O. J. Finn. “Renal allograft-infiltrating lymphocytes. A prospective analysis of in vitro growth characteristics and clinical relevance.” Transplantation 53, no. 2 (February 1992): 329–38. https://doi.org/10.1097/00007890-199202010-00014.
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  - Kirk, A. D., and O. J. Finn. “T cells expressing the antigen receptor mediate non-MHC directed human renal allograft cytotoxicity.” Surgical Forum 52 (1991): 384–86.
  - Kirk, A. D., B. A. Bowers, J. A. Moylan, and W. C. Meyers. “Toothbrush swallowing.” Arch Surg 123, no. 3 (March 1988): 382–84. https://doi.org/10.1001/archsurg.1988.01400270122020.
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  - Weiss, E. A., A. D. Kirk, and J. A. Wolfe. “The appearance of major histocompatibilit y complex class II antigens in rat small bowel allograft-induced graft-versus-host disease.” Transplantation Proceedings 19, no. 3 (January 1, 1987): 3019–21.
- Book Sections
  - Chambers, E. T., and A. D. Kirk. “Antilymphocyte globulin, monoclonal antibodies, and fusion proteins.” In Kidney Transplantation - Principles and Practice, 283–312, 2019. https://doi.org/10.1016/B978-0-323-53186-3.00019-X.
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  - Daneshmand, M. A., and A. D. Kirk. “Immunosuppression in organ transplantation.” In Fischer’s Mastery of Surgery, Seventh Edition, 1:141–50, 2018.
  - Lidsky, M. E., D. A. Bruno, and A. D. Kirk. “Chapter 111 - Liver and pancreas transplantation immunobiology.” In Blumgart’s Surgery of the Liver, Biliary Tract and Pancreas: Sixth Edition, 2–2:1726-1736.e3, 2017. https://doi.org/10.1016/B978-0-323-34062-5.00111-4.
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  - Lo, D. J., and A. D. Kirk. “Immune responses to transplants.” In Transplant Immunology, 142–63, 2015. https://doi.org/10.1002/9781119072997.ch8.
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  - MacConmara, M., I. Nwadei, and A. D. Kirk. “Immunosuppressive Biologic Agents.” In Transplantation of the Liver: Third Edition, 1343–53, 2015. https://doi.org/10.1016/B978-1-4557-0268-8.00096-8.
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  - Ruiz, R., and A. D. Kirk. “Long-Term Toxicity of Immunosuppressive Therapy.” In Transplantation of the Liver: Third Edition, 1354–63, 2015. https://doi.org/10.1016/B978-1-4557-0268-8.00097-X.
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  - Anderson, Douglas J., Benjamin M. Martin, Allan D. Kirk, and David H. Sachs. “Large Animal Models of Transplantation.” In TEXTBOOK OF ORGAN TRANSPLANTATION, 185–207, 2014.
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  - Badell, Raul, and Allan D. Kirk. “Mechanisms of Allograft Tolerance.” In TEXTBOOK OF ORGAN TRANSPLANTATION, 119–33, 2014.
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  - Charafeddine, Ali H., and Allan D. Kirk. “Induction Immunosuppressive Therapy.” In TEXTBOOK OF ORGAN TRANSPLANTATION, 717–31, 2014.
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  - Kirk, Allan D. “Textbook of Organ Transplantation Introduction.” In TEXTBOOK OF ORGAN TRANSPLANTATION, 3–4, 2014.
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  - Webber, Steven A., and Allan D. Kirk. “An Introduction to Pediatric Organ Transplantation.” In TEXTBOOK OF ORGAN TRANSPLANTATION, 1355–56, 2014.
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  - Kirk, A. D. “Antilymphocyte Globulin, Monoclonal Antibodies, and Fusion Proteins,” 287–313, 2013. https://doi.org/10.1016/B978-1-4557-4096-3.00020-9.
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  - Sayed, B. A., A. D. Kirk, T. C. Pearson, and C. P. Larsen. “Belatacept,” 314–19, 2013. https://doi.org/10.1016/B978-1-4557-4096-3.00021-0.
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  - Bruno, D. A., K. K. Dhanireddy, and A. D. Kirk. “Liver and pancreas transplantation immunobiology,” 2:1652–61, 2012. https://doi.org/10.1016/B978-1-4377-1454-8.00096-5.
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  - Srinivasan, S. K., H. L. Triemer, and A. D. Kirk. “Combination and Adjuvant Therapies to Facilitate the Efficacy of Costimulatory Blockade,” 407–28, 2012. https://doi.org/10.1002/9781444355628.ch28.
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  - Bruno, David A., and Allan D. Kirk. “Tolerance in Liver Transplantation.” In Liver Transplantation, 1–18. Humana Press, 2009. https://doi.org/10.1007/978-1-60327-028-1_1.
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  - Kirk, A. D. “Antibodies and Fusion Proteins.” In Kidney Transplantation: Principles and Practice, 309–32, 2008. https://doi.org/10.1016/B978-1-4160-3343-150024-4.
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  - Cendales, L. C., D. E. Kleiner, and A. D. Kirk. “Translational research in composite tissue allotransplantation.” In Transplantation of Composite Tissue Allografts, 43–54, 2008. https://doi.org/10.1007/978-0-387-74682-1_5.
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  - Kirk, A. D. “Antibodies and Fusion Proteins,” 309–32, 2008. https://doi.org/10.1016/B978-1-4160-3343-1.50024-4.
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  - Kirk, A. D., and E. A. Elster. “Immunology of transplantation,” 1705–36, 2008. https://doi.org/10.1007/978-0-387-68113-9_81.
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  - Kirk, Allan D., Douglas A. Hale, Elizabeth Ford, David E. Kleiner, Robert L. Kampen, Eric A. Elster, S John Swanson, et al. “Solid organ transplantation at the National Institutes of Health: development of a research-based transplantation practice.,” 131–44, 2005.
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- Other Articles
  - Bray, R. A., P. Brannon, C. Breitenbach, C. Bryan, D. -. F. Chen, J. Lai, T. McRacken, et al. “The new OPTN kidney allocation policy: potential for inequitable access among highly sensitized patients.” Am J Transplant, January 2015. https://doi.org/10.1111/ajt.13061.
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  - Kirk, A. D. “The cam-path forward.” Am J Transplant, January 2013. https://doi.org/10.1111/j.1600-6143.2012.04324.x.
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  - Stock, P., and A. D. Kirk. “The risk and opportunity of homeostatic repopulation.” Am J Transplant, July 2011. https://doi.org/10.1111/j.1600-6143.2011.03543.x.
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  - Kirk, A. D., S. J. Knechtle, C. P. Larsen, K. A. Newell, and T. C. Pearson. “Miles to go….” Am J Transplant, June 2011. https://doi.org/10.1111/j.1600-6143.2011.03542.x.
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  - Kirk, A. D., and S. Feng. “Surgeons and research: talent, training, time, teachers and teams.” Am J Transplant, February 2011. https://doi.org/10.1111/j.1600-6143.2010.03399.x.
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  - Kirk, A. D. “New in AJT.” American Journal of Transplantation, 2011. https://doi.org/10.1111/j.1600-6143.2010.03392.x.
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  - Kirk, A. D. “Now what?” Am J Transplant, November 2010. https://doi.org/10.1111/j.1600-6143.2010.03287.x.
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  - Jackson, Jennifer, Laurence Greenbaum, and Allan D. Kirk. “Transplantation and autosomal recessive polycystic kidney disease.” Nephrol News Issues, June 2010.
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  - Kirk, A. D. “What should work, may not.” Am J Transplant, March 2010. https://doi.org/10.1111/j.1600-6143.2010.03025.x.
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  - Kirk, A. D. “4D11: The Second Mouse?” Am J Transplant, August 2009. https://doi.org/10.1111/j.1600-6143.2009.02749.x.
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  - Kirk, A. D., and D. R. Salomon. “AJT's response to the National Institutes of Health public access regulations.” Am J Transplant, October 2008. https://doi.org/10.1111/j.1600-6143.2008.02363.x.
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  - Newell, K. A., L. C. Cendales, and A. D. Kirk. “Finding the right job for the tool: alemtuzumab and its role in renal transplantation.” Am J Transplant, July 2008. https://doi.org/10.1111/j.1600-6143.2008.02291.x.
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  - Cendales, Linda C., and Allan D. Kirk. “Nonhuman primates for the study of composite tissue allotransplantation.” Transplantation, January 27, 2007. https://doi.org/10.1097/01.tp.0000242527.32735.0d.
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  - Kirk, A. D., and J. A. Light. “Of ends and means.” Am J Transplant, October 2006. https://doi.org/10.1111/j.1600-6143.2006.01500.x.
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  - Kirk, A. D. “Meteorology and tolerance.” Am J Transplant, April 2006. https://doi.org/10.1111/j.1600-6143.2006.01244.x.
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  - Kirk, Allan D., and Peter A. Pinto. “Laparoscopic kidney donation: looking more than skin deep.” Am J Transplant, June 2005. https://doi.org/10.1111/j.1600-6143.2005.00956.x.
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  - Kirk, A. D. “Transplantation: Integrating the concepts of innate and acquired immunity with translational trials.” Current Opinion in Immunology, 2004. https://doi.org/10.1016/j.coi.2004.07.020.
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  - Kirk, Allan D. “Less is more: maintenance minimization as a step toward tolerance.” Am J Transplant, June 2003. https://doi.org/10.1034/j.1600-6143.2003.00138.x.
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  - Vanrenterghem, Yves, Kathleen Claes, Pieter Evenepoel, Dirk Kuypers, and Bart Maes. “Kidney transplantation with rabbit antithymocyte globulin and sirolimus monotherapy.” Lancet, March 15, 2003. https://doi.org/10.1016/S0140-6736(03)12752-3.
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  - Kirk, Allan D. “Location, location, location: regional immune mechanisms critically influence rejection.” Nat Med, June 2002. https://doi.org/10.1038/nm0602-553.
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  - Kirk, A. D. “Hitting the reset button for immune tolerance.” Nat Med, January 2001. https://doi.org/10.1038/83304.
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  - Kawai, T., D. Andrews, R. B. Colvin, D. H. Sachs, and A. B. Cosimi. “Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand.” Nat Med, February 2000. https://doi.org/10.1038/72162.
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  - Kirk, A. D. “Let’s blame the little guys: platelets as an instigator of allograft rejection.” Graft, 1999.
- Journal Issues
  - Eckardt, Kai-Uwe, Bertram L. Kasiske, and Martin G. Zeier. “Special Issue: KDIGO Clinical Practice Guideline for the Care of Kidney Transplant Recipients.” American Journal of Transplantation. Elsevier BV, November 2009. https://doi.org/10.1111/j.1600-6143.2009.02834.x.
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- Conference Papers
  - Chan, Norine W., Mary E. Moya-Mendez, Jacqueline B. Henson, Mark P. Sendak, William S. Knechtle, Nrupen A. Bhavsar, Suresh Balu, Allan D. Kirk, and Lisa M. McElroy. “Social Determinants of Health Data Capture Within National and Health System Data Sources.” In Journal of the American College of Surgeons, 235:S136–S136. Ovid Technologies (Wolters Kluwer Health), 2022. https://doi.org/10.1097/01.xcs.0000894008.17070.09.
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  - Xu, H., L. Wang, V. A. Bendersky, Q. Gao, Q. Li, and A. D. Kirk. “MTOR Inhibition Acts Directly on Endothelial Cells to Induce Contact-Independent Immune-Modulation of Allo-Specific T Cell Activation.” In American Journal of Transplantation, 22:409–409, 2022.
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  - Xu, H., L. Wang, and A. D. Kirk. “Sting but Not Mtor Signaling Regulates Exogenous Mitochondrion-Induced Endothelial Cell Mitophagy.” In American Journal of Transplantation, 22:740–740, 2022.
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  - David, E., M. Zhu, W. Parker, N. MacIver, A. D. Kirk, and E. T. Chambers. “The Effect of Undernutrition and Immunosuppression on Cytomegalovirus Specific T Cell Responses.” In American Journal of Transplantation, 20:749–749, 2020.
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  - David, E., M. Zhu, W. Parker, N. MacIver, A. D. Kirk, and E. T. Chambers. “Undernutrition and Hypoleptinemia Modulate Cytomegalovirus Infection.” In American Journal of Transplantation, 20:749–50, 2020.
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  - Devi, G. R., Z. Fitch, M. Song, M. Ribeiro, A. McGowan, X. Luo, B. H. Collins, and A. D. Kirk. “XIAP Enhances Xenoislet Survival: Novel Models to Evaluate Pretransplantation Gene Modifications.” In American Journal of Transplantation, 20:741–741, 2020.
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  - Fitch, Z. W., M. Song, R. Schmitz, F. Leopardi, M. Ribeiro, A. Miller, G. Devi, B. Collins, X. Luo, and A. D. Kirk. “Splenectomy Impedes B Cell Infiltration Associated with Rejection of Neonatal Porcine Islet Xenografts.” In American Journal of Transplantation, 20:757–757, 2020.
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  - Gerardo, C. J., E. Silvius, S. Schobel, J. Eppensteiner, L. McGowan, A. T. Limkakeng, A. D. Kirk, and E. A. Elster. “ASSOCIATION OF A CYTOKINE RESPONSE NETWORK WITH FUNCTIONAL RECOVERY FROM SNAKEBITE ENVENOMING.” In Toxicon, 182:S15–16, 2020.
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  - Moris, D. P., A. Atia, M. Rae, M. Song, L. Stempora, F. Leopardi, K. Williams, et al. “Th17 Cell Inhibition in a Costimulation Blockade Based Regimen for Vascularized Composite Allotransplantation Using A Non-Human Primate Model.” In American Journal of Transplantation, 20:537–537, 2020.
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  - Schmitz, R., M. S. Mulvihill, Z. W. Fitch, T. How, F. Leopardi, and A. D. Kirk. “Altering Homeostatic Repopulation with Thymic Irradiation and Donor Mesenchymal Stem Cell Infusions in a Nonhuman Primate Model.” In American Journal of Transplantation, 20:710–710, 2020.
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  - Shaw, B. I., H. Lee, C. Chan, R. B. Ettenger, P. Grimm, E. F. Reed, M. Sarwal, et al. “Obesity and Terminally Differentiated T Cells in Pediatric Kidney Transplantation.” In American Journal of Transplantation, 20:1012–1012, 2020.
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  - Shaw, B. I., R. Schmitz, D. M. Magnani, F. Leopardi, and A. D. Kirk. “Depletional Profiles of Human and Rhesus Specific Anti-Thymocyte Globulins in Rhesus Macaques.” In American Journal of Transplantation, 20:709–709, 2020.
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  - Song, M., Z. Fitch, K. Samy, Q. Gao, R. P. Davis, F. Leopard, R. Schmitz, et al. “Coagulation and Cd46 Transgene Modification in Neonatal Porcine Islet Xenotransplantation.” In American Journal of Transplantation, 20:361–361, 2020.
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  - Vicente, Diego, Seth Schobel, Simone Anfossi, Hannah Hensman, Felipe Lisboa, Thomas Davis, Christopher John Dente, Allan Douglas Kirk, George Calin, and Eric Andrew Elster. “Characterization of Cellular and Viral MicroRNA in Polytrauma Patients.” In Journal of the American College of Surgeons, 231:E59–E59, 2020.
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  - Gelbard, Rondi B., Hannah Hensman, Seth Schobel, Vivek Khatri, Brett M. Tracy, Christopher J. Dente, Timothy Buchman, Allan Kirk, and Eric Elster. “Random forest modeling can predict infectious complications following trauma laparotomy.” In J Trauma Acute Care Surg, 87:1125–32, 2019. https://doi.org/10.1097/TA.0000000000002486.
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  - Corey, Kristin, Joshua Helmkamp, Allan D. Kirk, Suresh Balu, David Thompson, Leila Mureebe, Joshua Watson, Keith Marsolo, Lesley Curtis, and Mark Sendak. “Assessing Quality of Real-World Data Supplied by an Automated Surgical Data Pipeline.” In Journal of the American College of Surgeons, 229:S89–S89. ELSEVIER SCIENCE INC, 2019.
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  - Fitch, Z. W., Q. Gao, R. P. Davis, M. S. Mulvihill, M. Song, F. Leopardi, M. Ribeiro, et al. “Islet Xenotransplantation: A Quest for Clinically Available Immunosuppression Regimens.” In American Journal of Transplantation, 19:473–74. WILEY, 2019.
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  - Schmitz, R., M. S. Mulvihill, P. M. Schroder, Z. Fitch, F. Leopardi, D. Magnani, J. Kwun, S. J. Knechtle, and A. D. Kirk. “Depletional Induction Therapy in Non-Human Primates - Preclinical Modeling of Polyclonal Depletion with Rhesus-Specific ATG.” In American Journal of Transplantation, 19:597–597. WILEY, 2019.
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  - Song, M., K. Samy, Q. Gao, R. P. Davis, F. Leopard, Z. Fitch, C. Bennett, G. R. Devi, B. H. Collins, and A. D. Kirk. “CD46 Transgene Modification and Thrombosis in Neonatal Porcine Islet Xenotransplantation.” In American Journal of Transplantation, 19:430–430. WILEY, 2019.
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  - Chambers, E. T., O. Martinez, M. Robien, C. Chan, R. Ettenger, P. Grimm, H. Lee, et al. “NK Cells Are Associated with Alloimmune Failure in Transplanted Children.” In American Journal of Transplantation, 19:339–339. WILEY, 2019.
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  - Shaw, B. I., D. K. Cheng, Q. Cheng, C. R. Acharya, A. D. Kirk, and E. T. Chambers. “A Novel Genomic Approach for Acute Rejection across All Age Groups in Kidney Transplantation.” In American Journal of Transplantation, 19:519–519. WILEY, 2019.
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  - Shaw, B. I., L. Stempora, C. Chan, R. B. Ettenger, P. C. Grimm, H. Lee, E. F. Reed, et al. “Antithymocyte Globulin is Associated with Mature T Cell Phenotypes and Decreased Risk of Non-EBV Infections in Transplanted Children.” In American Journal of Transplantation, 19:466–67. WILEY, 2019.
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  - Belard, Arnaud, Timothy Buchman, Christopher J. Dente, Benjamin K. Potter, Allan Kirk, and Eric Elster. “The Uniformed Services University's Surgical Critical Care Initiative (SC2i): Bringing Precision Medicine to the Critically Ill.” In Mil Med, 183:487–95, 2018. https://doi.org/10.1093/milmed/usx164.
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  - Johnston, B. E., C. A. Quigley, S. M. Griffin, A. T. Limkakeng, M. D. Darrabie, J. A. Cheeseman, A. D. Kirk, and E. A. Elster. “313 Evaluation of Phenylalanine and Tyrosine Concentrations in Traumatically Injured Patients.” In Annals of Emergency Medicine, 70:S123–S123. Elsevier BV, 2017. https://doi.org/10.1016/j.annemergmed.2017.07.384.
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  - Darrabie, Marcus D., Jaewoo Lee, Jennifer Cheeseman, Alexander T. Limkakeng, Steven N. Vaslef, Bruce A. Sullenger, and Allan D. Kirk. “Toll-Like Receptor Signaling as a Prognostic Tool in Trauma Patients.” In Journal of the American College of Surgeons, 223:S159–60. Ovid Technologies (Wolters Kluwer Health), 2016. https://doi.org/10.1016/j.jamcollsurg.2016.06.346.
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  - Cendales, Linda C., Matthew Levine, Stephen Bartlett, Jennifer Cheeseman, Cinthia I. Drachenberg, Wayne W. Hancock, Marybeth Joshi, et al. “Skin as a harbinger of rejection of underlying structures in VCA: Concordance or discordance?” In Transplantation, 100:S813–S813. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Lo, D., D. Anderson, F. Leopardi, M. Song, E. Strobert, S. Chapin, B. Devens, E. Karrer, and A. Kirk. “A Pilot Trial Targeting the ICOS-ICOS-L Pathway in Nonhuman Primate Kidney Transplantation.” In Transplantation, 98:288–288. Ovid Technologies (Wolters Kluwer Health), 2014. https://doi.org/10.1097/00007890-201407151-00896.
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  - Best, Victoria, Stuart J. Knechtle, Allan D. Kirk, and Arash Grakoui. “Potential role for intrahepatic CD34+cells in immunity to hepatitis C virus.” In Hepatology, 56:1109A-1110A. WILEY-BLACKWELL, 2012.
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  - Freitas, A. M., A. B. Farris, F. Leopardi, M. Song, E. Strobert, A. D. Kirk, and L. C. Cendales. “Costimulation Blockade Based Regimens Prolong Graft Survival of Vascularized Composite Allografts in Non-Human Primates.” In American Journal of Transplantation, 12:33–33. WILEY-BLACKWELL, 2012.
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  - Kwun, J., B. Oh, A. Gibby, R. Ruhil, V. Lu, O. P. Bulut, M. Song, et al. “Patterns of De Novo Allo B Cells and Antibody Formation in Chronic Cardiac Allograft Rejection after Alemtuzumab Treatment.” In American Journal of Transplantation, 12:278–278. WILEY-BLACKWELL, 2012.
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  - Oh, B., J. Kwun, R. Ruhil, A. Gibby, E. Page, V. Lu, D. Kim, et al. “Rapamycin Enhances Donor-Specific Antibody and Chronic Rejection of Full MHC Mismatched Cardiac Allografts after Alemtuzumab Treatment.” In American Journal of Transplantation, 12:463–463. WILEY-BLACKWELL, 2012.
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  - Singh, K., L. Stempora, A. D. Kirk, C. P. Larsen, B. B. Blazar, and L. S. Kean. “Rhesus Macaque Natural CD4 Regulatory T Cells Exhibit Decreased Proliferation But Enhanced Suppression After Pulsing with Sirolimus.” In Biology of Blood and Marrow Transplantation, 18:S201–S201. Elsevier BV, 2012. https://doi.org/10.1016/j.bbmt.2011.12.523.
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  - Kirk, Allan D. “Where Has All the Science Gone?” In American Journal of Transplantation, 12:51–51. WILEY-BLACKWELL, 2012.
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  - Singh, Karnail, Natalia Kozyr, Linda Stempora, Allan D. Kirk, Christian P. Larsen, Bruce R. Blazar, and Leslie S. Kean. “Sirolimus Inhibits Proliferation but Enhances Suppressive Activity of Rhesus Macaque Natural CD4 Regulatory T Cells.” In Blood, 118:461–461. AMER SOC HEMATOLOGY, 2011.
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  - Gupta, Nitika A., Vasantha L. Kolachala, Rong Jiang, Carlos R. Abramowsky, Stuart J. Knechtle, and Allan D. Kirk. “PORTAL VENOUS FLOW ABNORMALITIES ARE PRESENT AND ARE ACCENTUATED AFTER ISCHEMIA REPERFUSION INJURY OF A STEATOTIC LIVER.” In Hepatology, 54:1168A-1168A. WILEY-BLACKWELL, 2011.
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  - Safley, Susan A., Norma S. Kenyon, Dora M. Berman, Antonello Pileggi, Norman Kenyon, Hong Cui, Idelberto Badell, et al. “Function of microencapsulated adult porcine islet xenografts in streptozotocin-diabetic non-human primates.” In Xenotransplantation, 18:277–277. WILEY-BLACKWELL, 2011.
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  - Beus, J. M., D. Duan, S. H. Speck, C. P. Larsen, A. D. Kirk, and L. S. Kean. “Overcoming Heterologous Immunity: Virus-Mediated, Costimulation Blockade-Resistant Transplant Rejection Is Reversed by Blocking T Cell Adhesion Pathways.” In American Journal of Transplantation, 11:29–29. WILEY-BLACKWELL, 2011.
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  - Beus, J. M., M. Subramanian, A. K. Mehta, R. Eady, and A. D. Kirk. “CMV and EBV Viremia Occur as Independent Consequences of Immunosuppression.” In American Journal of Transplantation, 11:456–57. WILEY-BLACKWELL, 2011.
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  - Cheeseman, J., E. Begley, S. Thomas, R. Eady, S. Monday, K. Bryant, R. Jones, et al. “Development of an Integrated Research Support Service for Clinical Transplant Research.” In American Journal of Transplantation, 11:241–42. WILEY-BLACKWELL, 2011.
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  - Ferrer, I. R., M. E. Wagener, A. D. Kirk, C. P. Larsen, and M. L. Ford. “Rapamycin Augments CD8(+) T Cell Responses to Latent and Chronic Viral Infections but Not Heterologous Immune Graft-Reactive Responses.” In American Journal of Transplantation, 11:153–153. WILEY-BLACKWELL, 2011.
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  - Ferrer, I. R., M. E. Wagener, M. Song, A. D. Kirk, M. L. Ford, and C. P. Larsen. “CD40/CD154 Pathway Blockade Mediates Conversion of Antigen-Specific CDC+ T Cells into FoxP3(+) Cells and Inhibits CD8(+) T Cell Effector Function.” In American Journal of Transplantation, 11:342–342. WILEY-BLACKWELL, 2011.
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  - Ford, M. L., N. M. Reisman, T. L. Floyd, M. E. Wagener, A. D. Kirk, and C. P. Larsen. “LFA-1 Blockade Induces Effector and Regulatory T Cell Enrichment in Lymph Nodes and Increases Effector T Cell Death.” In American Journal of Transplantation, 11:153–153. WILEY-BLACKWELL, 2011.
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  - Freitas, A. M., A. J. Page, E. Dai, A. B. Farris, F. Leopardi, M. Song, E. Strobert, A. D. Kirk, and L. C. Cendales. “Vascularized Composite Allografts: Experience with Costimulation Blockade in Non-Human Primates.” In American Journal of Transplantation, 11:283–84. WILEY-BLACKWELL, 2011.
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  - Haridas, D., M. E. Wagener, A. D. Kirk, C. P. Larsen, and M. L. Ford. “Targeting the "Therapeutic Window" in Transplantation Via Differential Expression of LFA-1 on Pathogen vs. Allograft-Specific CD8(+) T Cells.” In American Journal of Transplantation, 11:474–474. WILEY-BLACKWELL, 2011.
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  - Kim, D., J. Beus, A. Gibby, L. Kean, A. D. Kirk, S. J. Knechtle, and J. Kwun. “Differential Effect of Costimulation Blockade on the Primary vs. Latent Infection in Minor Mismatched Skin Transplantation.” In American Journal of Transplantation, 11:523–523. WILEY-BLACKWELL, 2011.
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  - Kim, E. J., J. Kwun, A. J. Page, F. Leopardi, A. C. Gibby, A. D. Kirk, and S. J. Knechtle. “A Non-Human Primate Model for Alloantibody Production after T Cell Depletion.” In American Journal of Transplantation, 11:369–369. WILEY-BLACKWELL, 2011.
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  - Kim, E. J., J. Kwun, A. J. Page, F. Leopardi, A. C. Gibby, A. D. Kirk, and S. J. Knechtle. “Alefacept Overcomes Memory T Cell Barrier after T Cell Depletion with a Novel Recombinant CD3-Immunotoxin (A-DmDT390-ScfbDb) in a Non-Human Primate Renal Transplantation Model.” In American Journal of Transplantation, 11:453–453. WILEY-BLACKWELL, 2011.
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  - Kirk, A. D., S. Mead, H. Xu, A. Mehta, A. Guasch, J. Cheeseman, J. Joseph, et al. “Kidney Transplantation Using Alemtuzumab Induction and Belatacept/Sirolimus Maintenance Therapy.” In American Journal of Transplantation, 11:45–45. WILEY-BLACKWELL, 2011.
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  - Kitchens, W. H., A. D. Kirk, C. P. Larsen, and M. L. Ford. “Defining Populations of Pathogen-Elicited Donor-Specific Memory T Cells with Different Susceptibility to Costimulatory Blockade.” In American Journal of Transplantation, 11:153–153. WILEY-BLACKWELL, 2011.
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  - Kitchens, W. H., D. Haridas, A. D. Kirk, C. P. Larsen, and M. L. Ford. “Integrin Antagonists Prevent Costimulatory Blockade-Resistant Transplant Rejection by CD8(+) Memory T Cells.” In American Journal of Transplantation, 11:477–477. WILEY-BLACKWELL, 2011.
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  - Lo, D. J., T. Weaver, F. Leopardi, M. Song, A. B. Farris, N. A. Turgeon, A. K. Mehta, C. P. Larsen, and A. D. Kirk. “Adjuvant Treatment with Alefacept (LFA-3-Ig) Promotes Belatacept-Based Immunomodulation in Renal Transplantation in Nonhuman Primates.” In American Journal of Transplantation, 11:172–73. WILEY-BLACKWELL, 2011.
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  - Mehta, A. K., M. McCausland, D. J. Lo, J. Joseph, J. Cheeseman, R. Elbein, T. Gourley, et al. “Chronic Kidney Disease and CMV Drive Patient Specific Pre-Transplant Immune Deviations Toward Terminal Differentiation and Exhaustion.” In American Journal of Transplantation, 11:388–388. WILEY-BLACKWELL, 2011.
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  - Mehta, A. K., M. McCausland, J. Joseph, J. Cheeseman, J. Duraiswamy, P. Mulupuri, T. Gourley, et al. “Immunologic Ramifications of Depletion Induction Therapy and CMV Viremia in a Renal Transplant Cohort.” In American Journal of Transplantation, 11:389–389. WILEY-BLACKWELL, 2011.
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  - Mehta, A. K., P. L. Turner, H. Xu, L. L. Stempora, S. Nadler, A. D. Kirk, and C. P. Larsen. “The Effect of Costimulation Blockade with Belatacept on EBV Specific Immunity.” In American Journal of Transplantation, 11:346–346. WILEY-BLACKWELL, 2011.
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  - Neujahr, D. C., A. Mohammed, O. Ulukpo, E. C. Lawrence, F. Fernandez, A. Pickens, S. D. Force, C. P. Larsen, and A. D. Kirk. “Cumulative Exposure to Gamma Interferon Dependent Chemokines CXCL9 and CXCL10 Is Associated with Worse Function after Lung Transplantation.” In American Journal of Transplantation, 11:35–35. WILEY-BLACKWELL, 2011.
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  - Neujahr, D. C., A. Mohammed, O. Ulukpo, F. Fernandez, A. Pickens, E. C. Lawrence, K. C. Easley, S. D. Force, A. D. Kirk, and C. P. Larsen. “Cumulative Exposure to CD8 T Cells with Granzyme B Is Associated with Worse Lung Function Early after Lung Transplantation.” In American Journal of Transplantation, 11:395–395. WILEY-BLACKWELL, 2011.
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  - Srinivasan, S. K., A. J. Page, K. Singh, A. D. Kirk, C. P. Larsen, and L. S. Kean. “Identifying a Signature of Transplant Rejection in Non-Human Primates: Upregulation of CD95 Is a Site-Specific Marker That Strongly Correlates with Transplant Rejection.” In American Journal of Transplantation, 11:391–92. WILEY-BLACKWELL, 2011.
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  - Srinivasan, S., A. Page, K. Singh, K. Hamby, A. Kirk, C. Larsen, and L. Kean. “New Evidence for Synergy between Combined Blockade of the CD40 and CD28/mTOR Pathways in a Rhesus Macaque Transplant Model.” In American Journal of Transplantation, 11:174–75. WILEY-BLACKWELL, 2011.
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  - Xu, H., A. K. Mehta, S. Mead, J. Cheeseman, L. Stempora, T. C. Pearson, C. Larsen, and A. D. Kirk. “Belatacept, but Not Calcineurin Inhibitors, Preserve Human CMV-Specific Memory Cell Responses.” In American Journal of Transplantation, 11:44–44. WILEY-BLACKWELL, 2011.
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  - Xu, H., E. J. Kim, C. Larsen, and A. D. Kirk. “The Chemokines CXCL10 and CXCL11 Are Produced Directly by Renal Proximal Tubular Epithelial Cells in Response to Monocyte Derived TNF-alpha.” In American Journal of Transplantation, 11:233–233. WILEY-BLACKWELL, 2011.
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  - Farris, A. B., J. Kong, C. Chisolm, H. M. Gebel, R. A. Bray, C. Cohen, D. J. Brat, J. H. Saltz, A. D. Kirk, and R. Hennigar. “HLA-DR Immunohistochemistry Quantitation in Renal Allograft Biopsies: Objective Discrimination of Rejection and Other Pathologic Processes.” In Modern Pathology, 24:344A-344A. NATURE PUBLISHING GROUP, 2011.
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  - Farris, A. B., J. Kong, C. Chisolm, H. M. Gebel, R. A. Bray, C. Cohen, D. J. Brat, J. H. Saltz, A. D. Kirk, and R. Hennigar. “HLA-DR Immunohistochemistry Quantitation in Renal Allograft Biopsies: Objective Discrimination of Rejection and Other Pathologic Processes.” In Laboratory Investigation, 91:344A-344A. NATURE PUBLISHING GROUP, 2011.
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  - Beus, Jonathan, Kelly Hamby, Allan D. Kirk, Christian P. Larsen, Samuel H. Speck, and Leslie Kean. “Identification of a Costimulation Blockade Resistant Mechanism of Bone Marrow Allograft Rejection Induced by Infection with a Murine EBV Homologue.” In Blood, 116:625–625. AMER SOC HEMATOLOGY, 2010.
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  - Gupta, Nitika A., Jean Kwun, Allan D. Kirk, Frank A. Anania, Rene Romero, and Stuart J. Knechtle. “ROLE OF GLP-1R AGONISTS IN DECREASING HEPATIC STEATOSIS AND APOPTOSIS IN OB/OB MICE UNDERGOING ISCHEMIA REPERFUSION INJURY.” In Hepatology, 52:1041A-1042A. WILEY-BLACKWELL, 2010.
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  - Jackson, J., J. Rossio, L. Kean, and A. Kirk. “Non-Invasive Test for Renal Transplant Rejection in Children.” In Pediatric Nephrology, 25:1887–88. SPRINGER, 2010.
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  - Badell, I. R., J. B. Mendel, J. M. Robertson, B. E. Johnson, X. Wang, R. Wang, N. N. Iwakoshi, K. A. Reimann, A. D. Kirk, and Christian P. Larsen. “In Vivo Characterization of a Novel Recombinant Anti-CD40 Monoclonal Antibody in Nonhuman Primates.” In American Journal of Transplantation, 10:214–214. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Badell, I. R., P. W. Thompson, A. P. Turner, J. G. Avila, J. A. Cano, J. M. Robertson, F. V. Leopardi, et al. “Combination CD28/LFA-1 Blockade Promotes Islet Allograft Survival in Nonhuman Primates.” In American Journal of Transplantation, 10:91–91. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Badell, I. R., P. W. Thompson, A. P. Turner, J. G. Avila, J. A. Cano, J. M. Robertson, F. V. Leopardi, et al. “A Novel Non-Depleting Anti-CD40 Antibody Prolongs Allogeneic Islet Survival in Nonhuman Primates.” In American Journal of Transplantation, 10:146–146. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Cherikh, Wida S., Robert A. Metzger, Stephen Arcona, and Allan D. Kirk. “Association of Discharge Maintenance Immunosuppression with Post-Transplant Diabetes Mellitus (PTDM) in Adult Recipients of Primary Kidney Transplants.” In American Journal of Transplantation, 10:244–244. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Cherikh, Wida S., Robert A. Metzger, and Allan D. Kirk. “Comparison of Interleukin-2 Receptor Antibody Induction with Polyclonal Antibody Induction on Outcomes in Adult Recipients of Primary Deceased and Living Donor Kidney Transplants.” In American Journal of Transplantation, 10:51–51. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Ferrer, Ivana R., Maylene E. Wagener, Allan D. Kirk, Mandy L. Ford, and Christian P. Larsen. “CD40/CD154 Pathway Blockade Prolongs Graft Survival While Inhibiting CD8(+) T Cell Activation and Differentiation.” In American Journal of Transplantation, 10:361–361. WILEY-BLACKWELL, 2010.
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  - Ferrer, Ivana R., Maylene E. Wagener, Jennifer M. Robertson, Alexa P. Turner, Allan D. Kirk, Christian P. Larsen, and Mandy L. Ford. “Rapamycin Augments Pathogen-Specific but Not Donor-Reactive CD8(+) T Cell Responses.” In American Journal of Transplantation, 10:159–159. WILEY-BLACKWELL, 2010.
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  - Ford, Mandy L., William H. Kitchens, Jennifer M. Robertson, Allan D. Kirk, and Christian P. Larsen. “Anti-LFA-1 Synergizes with CD28/CD154 Blockade To Inhibit Anti-Donor Cytotoxicity and Promote Graft Survival in Recipients Possessing Donor-Reactive Memory T Cells.” In American Journal of Transplantation, 10:41–41. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Kwun, Jean, Andrew Page, Frank Leopardi, Adriana Cardona, Allan D. Kirk, and Stuart J. Knechtle. “Limited Effect of a Novel Recombinant CD3-Immunotoxin (A-DmDT390-ScfbDb) in a Non-Human Primate Model.” In American Journal of Transplantation, 10:214–214. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Kwun, Jean, Neal Iwakoshi, Adriana Cardona, Dongwoon Kim, Justin Mendel, Allan D. Kirk, and Stuart J. Knechtle. “Abrogation of Alloreactive B Cells and Alloantibody after TACI-Ig Treatment in Alemtuzumab Treated CD52Tg Cardiac Allograft Recipient Mice.” In American Journal of Transplantation, 10:116–17. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Lo, Denise J., Tim A. Weaver, Linda Stempora, Aneesh K. Mehta, Mandy L. Ford, Christian P. Larsen, and Allan D. Kirk. “Selective Targeting of Human Alloresponsive CD8(+) Effector Memory T Cells Based on CD2 Expression.” In American Journal of Transplantation, 10:558–558. WILEY-BLACKWELL, 2010.
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  - Mendel, Brett, Jean Kwun, Adriana Cardona, Kate M. Smith, Allan D. Kirk, Stuart Knechtle, and Neal N. Iwakoshi. “Unique Alloreactive B-Cell Development in an Alemtuzumab Treated CD52 Transgenic Cardiac Allograft Recipient Mice.” In American Journal of Transplantation, 10:400–400. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Mohammed, Aminu, Onome K. Ulukpo, Andres A. Pelaez, Allan M. Ramirez, E. C. Lawrence, Seth D. Force, Kirk C. Easley, Christian P. Larsen, Allan D. Kirk, and David C. Neujahr. “Combined Bronchoalveolar Lavage (BAL) Chemokine Scores Correlate with Spirometry in a Longitudinal Analysis of Lung Transplantation.” In American Journal of Transplantation, 10:487–487. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Mohammed, Aminu, Onome Ulukpo, Jennifer A. Jackson, Andres Pelaez, Allan M. Ramirez, Anthony A. Gal, E. C. Lawrence, et al. “Elevated Bronchoalveolar Lavage Fluid (BAL) CXCL9 and CXCL10 Levels Correlate with ACR in Human Lung Transplants.” In American Journal of Transplantation, 10:145–145. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Reisman, Natalie M., Maylene Wagener, Allan D. Kirk, Christian P. Larsen, and Mandy L. Ford. “'Lymphoid Urban Planning': Effects of Blockade of the LFA:ICAM Interaction in Lymphocyte Trafficking.” In American Journal of Transplantation, 10:365–365. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Reisman, Natalie M., Maylene Wagener, Ivana R. Ferrer, Allan D. Kirk, Christian P. Larsen, and Mandy L. Ford. “Beyond Trafficking: Blockade of LFA-1/ICAM Critically Impacts CD8+T Cell Acquisition of Donor-Specific Cytokine Production and Cytolytic Activity.” In American Journal of Transplantation, 10:463–463. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Thompson, P. W., I. R. Badell, A. P. Turner, J. Avila, J. Cano, E. A. Strobert, F. V. Leopardi, et al. “Towards a Translatable Regimen for Islet Xenotransplantation in Nonhuman Primates.” In American Journal of Transplantation, 10:187–187. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Turgeon, Nicole A., Jose A. Cano, Jennifer J. Hutchinson, I Raul Badell, Andrew J. Page, Allan D. Kirk, Thomas C. Pearson, and Christian P. Larsen. “Experience with a Novel Immunosuppressive Regimen To Facilitate Single Donor Islet Cell Transplantation Using Efalizumab.” In American Journal of Transplantation, 10:122–122. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Neujahr, D. C., A. Mohammed, O. Ulukpo, A. Pelaez, A. Ramirez, E. C. Lawrence, S. D. Force, A. A. Gal, C. P. Larsen, and A. D. Kirk. “150: Flow Cytometric Parameters of CD8 Lavage Cells in Detection of Acute Cellular Rejection in Lung Transplant.” In The Journal of Heart and Lung Transplantation, 29:S55–S55. Elsevier BV, 2010. https://doi.org/10.1016/j.healun.2009.11.159.
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  - Ford, Mandy L., Craig M. Steeds, Maylene E. Wagener, Jennifer M. Robertson, Samantha S. Hanna, Allan D. Kirk, and Christian P. Larsen. “Anti-LFA-1 Synergizes with CD28/CD154 Blockade To Inhibit Anti-Donor Cytotoxicity and Promote Graft Survival in Recipients Possessing Donor-Reactive Memory T Cells.” In American Journal of Transplantation, 10:9–9. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Tso, Paul L., Nicole A. Turgeon, Kenneth A. Newell, Thomas C. Pearson, Christian P. Larsen, and Allan D. Kirk. “What Is Optimal Induction Therapy for Expanded Criteria Donor Kidneys?” In American Journal of Transplantation, 10:31–31. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Miller, Weston, Caleb E. Wheeler, Angela Panoskaltsis-Mortari, Allan D. Kirk, Christian P. Larsen, Bruce R. Blazar, and Leslie S. Kean. “Prevention of Acute GvHD During MHC Haploidentical BMT: Evaluating the Efficacy of T-Cell Costimulation Blockade Using a Novel Rhesus Macaque Transplant Model.” In Blood, 114:968–69. AMER SOC HEMATOLOGY, 2009.
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  - Hon, Huiming, Luke Shen, James R. Spivey, Allan D. Kirk, and Arash Grakoui. “STIMULATION OF LIVER-RESIDENT, BUT NOT CIRCULATING PLASMACYTOID DENDRITIC CELLS WITH TOLL-LIKE RECEPTOR AGONISTS RESULTS IN HIGH LEVELS OF INTERFERON ALPHA SECRETION DURING CHRONIC HCV INFECTION.” In Hepatology, 50:932A-933A. JOHN WILEY & SONS INC, 2009.
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  - Badell, Idelberto, Alexandra Turner, Jose Avila, Jose Cano, Brandi Johnson, Frank Leopardi, Sarah Swygert, Elizabeth Strobert, Allan Kirk, and Christian Larsen. “A novel calcineurin inhibitor- and sirolimus-free anti-LFA-1-based therapy enhances allogeneic islet survival and function in nonhuman primates.” In Xenotransplantation, 16:314–314. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Sam, Wai-Johnn, Christine E. Chamberlain, Su-Jun Lee, Joyee A. Goldstein, Douglas A. Hale, Allan D. Kirk, Roslyn B. Mannon, and Yuen Yi Hon. “SIROLIMUS DOSE-NORMALIZED TROUGHS WERE AFFECTED BY TIME POST SIROLIMUS INITIATION, CONCOMITANT TACROLIMUS THERAPY, AND MDR-1 3435C > T POLYMORPHISM IN RENAL TRANSPLANT PATIENTS WHO ARE CYP3A5 NON-EXPRESSERS.” In Journal of Clinical Pharmacology, 49:1107–1107. SAGE PUBLICATIONS INC, 2009.
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  - Badell, Idelberto R., Alexandra P. Turner, Jose A. Cano, Jose G. Avila, Brandi E. Johnson, Frank V. Leopardi, Sarah G. Swygert, Elizabeth A. Strobert, Allan D. Kirk, and Christian P. Larsen. “A novel calcineurin inhibitor– and sirolimus-free anti-LFA-1-based therapy enhances allogeneic islet survival and function in nonhuman primates.” In Journal of the American College of Surgeons, 209:S56–S56. Ovid Technologies (Wolters Kluwer Health), 2009. https://doi.org/10.1016/j.jamcollsurg.2009.06.133.
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  - Rigby, Mark B., Alex Huang, Danxia Duan, Allan D. Kirk, and Christian P. Larsen. “CD28/154 Blockade Disrupts the Development of Diabetogenic T Cells while Permitting Regulatory T Cell Expansion.” In Diabetes, 58:A324–A324. AMER DIABETES ASSOC, 2009.
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  - Miller, W. P., C. E. Wheeler, A. Panoskaltsis-Mortari, A. D. Kirk, C. P. Larsen, B. R. Blazar, and L. S. Kean. “Prevention Of Acute GvHD During Haplo-BMT: Evaluating The Efficacy Of T-Cell Costimulation Blockade Using A Novel Rhesus Macaque Transplant Model.” In Biology of Blood and Marrow Transplantation, 15:114–15. Elsevier BV, 2009. https://doi.org/10.1016/j.bbmt.2008.12.354.
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  - Neujahr, D. C., A. Pelaez, A. Ramirez, S. D. Force, E. C. Lawrence, A. C. Cardona, A. D. Kirk, and C. P. Larsen. “455: Surgical Repair of Gastroesophageal Reflux in Lung Transplant Recipients Is Associated with Decreased Armed Effector T Cells and Increased Exhausted T Cells within the Allograft.” In The Journal of Heart and Lung Transplantation, 28:S224–S224. Elsevier BV, 2009. https://doi.org/10.1016/j.healun.2008.11.462.
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  - Agarwal, A., A. Metha, K. Kokko, N. A. Turgeon, P. Y. Tso, K. A. Newell, C. P. Larsen, and A. D. Kirk. “Impact of Rabbit Anti-Thymocyte Globulin Induction Therapy on Reactivation of BK Virus in Renal Transplant Recipients.” In American Journal of Transplantation, 9:422–422. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Agarwal, A., F. V. Leopardi, T. A. Weaver, N. N. Iwakoshi, C. P. Larsen, and A. D. Kirk. “Development of Novel Technologies for Monitoring Allospecific Humoral Immunity in a Non-Human Primate Model.” In American Journal of Transplantation, 9:703–703. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Agarwal, A., J. G. Avila, N. A. Turgeon, M. H. Sears, A. P. Turner, M. C. Russell, J. Sarimento, A. D. Kirk, T. C. Pearson, and C. P. Larsen. “Total Pancreatectomy and Autologous Islet Transplantation for Chronic Pancreatitis: Long Term Assesment of Graft Function.” In American Journal of Transplantation, 9:712–712. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Agarwal, A., N. A. Turgeon, K. M. Smith, J. B. Mendel, C. P. Larsen, A. D. Kirk, and N. N. Iwakoshi. “Novel Functional Assays of Human Allospecific Peripheral Memory B Cells Demonstrating Allospecific Antibody Production.” In American Journal of Transplantation, 9:471–471. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Ahmed, Z., A. Charafeddine, S. Hanna, T. A. Weaver, N. N. Iwakoshi, L. S. Kean, M. L. Ford, C. P. Larsen, and Allan D. Kirk. “Alemtuzumab-Mediated Depletion in CD52 Transgenic (Tg) Mice: A Model of Memory-Dominant, Lymphopenic Allograft Rejection.” In American Journal of Transplantation, 9:541–42. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Avila, Jose G., Al-Mamari Saif, Jose A. Cano, Neal Iwakoshi, Allan D. Kirk, Thomas Pearson, Athanassios Sambanis, and Christian P. Larsen. “Optimization of Neonatal Porcine Pancreatic Islets for Transplantation by the Use of a Novel Bioreactor Device during Cell Culture.” In American Journal of Transplantation, 9:669–669. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Avila, Jose G., Avinash Agarwal, Nicole Turgeon, Jose A. Cano, Alexandra Turner, Maria C. Russell, Allan D. Kirk, Thomas Pearson, and Christian P. Larsen. “Identification of Critical Factors Leading to Successful Islet Isolations and Transplantation.” In American Journal of Transplantation, 9:403–4. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Avila, Jose G., Jose A. Cano, Avinash Agarwal, Neal Iwakoshi, Abraham Matar, Maria C. Russell, Alexandra Turner, et al. “Time Profiles of Specific Physiologic and Genetic Parameters of Neonatal Porcine Pancreatic Islets.” In American Journal of Transplantation, 9:469–469. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Coley, Shana M., Sarah G. Swygert, Mingqing Song, Allan D. Kirk, and Christian P. Larsen. “Graft-Specific Action of IFN gamma Maintains Allograft Survival after Costimulation Blockade.” In American Journal of Transplantation, 9:718–718. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Ferrer, Ivana R., Samantha S. Hanna, Allan D. Kirk, Mandy L. Ford, and Christian P. Larsen. “Impact of CD40/CD154 Pathway Blockade on Donor-Reactive T Cell Expansion and Differentiation.” In American Journal of Transplantation, 9:631–631. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Ford, Mandy L., Maylene E. Wagener, Samantha S. Cooper, Allan D. Kirk, and Christian P. Larsen. “Overcoming the Memory Barrier: Role of Anti-LFA-1 in Promoting Long-Term Graft Survival in Recipients Possessing Donor-Reactive Memory T Cells.” In American Journal of Transplantation, 9:536–536. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Ford, Mandy L., Tamara L. Floyd, Maylene E. Wagener, Samantha S. Hanna, Linda Stempora, Rose Hendrix, Allan D. Kirk, and Christian P. Larsen. “Impact of Naive Donor-Reactive Precursor Frequency on the Differentiation of Costimulation-Independent CD8+Memory T Cells.” In American Journal of Transplantation, 9:333–333. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Gao, T., C. E. Chamberlain, S. Lee, J. A. Goldstein, M. S. Ring, D. A. Hale, A. D. Kirk, R. B. Mannon, and Y. Hon. “DIFFERING SIROLIMUS-INDUCED HYPERLIPIDEMIA AND RESPONSE TO STATIN THERAPY BETWEEN CYP3A5 EXPRESSERS AND NON-EXPRESSERS IN KIDNEY TRANSPLANTATION.” In Clinical Pharmacology & Therapeutics, 85:S74–S74. NATURE PUBLISHING GROUP, 2009.
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  - Kirk, A. D., S. Mirhosseini, and B. Afghani. “DRUG SUSCEPTIBILITY TRENDS AMONG COMMUNITY ACQUIRED AND HOSPITAL ACQUIRED SOFT TISSUE INFECTIONS.” In Journal of Investigative Medicine, 57:239–239. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Mehta, Aneesh K., Jose G. Avila, Rose C. Hendrix, Avinash Agarwal, Allan D. Kirk, Thomas C. Pearson, and Christian P. Larsen. “Transmission of Latent Viruses in Islet Cell Transplantation.” In American Journal of Transplantation, 9:405–405. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Miller, Weston, Caleb Wheeler, Angela Panoskaltsis-Mortari, Allan Kirk, Christian P. Larsen, Bruce R. Blazar, and Leslie Kean. “Prevention of Acute GvHD during Haplo-BMT: Evaluating the Efficacy of T-Cell Costimulation Blockade Using a Novel Rhesus Macaque Transplant Model.” In American Journal of Transplantation, 9:225–225. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Mohammed, Aminu, Geoffrey Lam, Adrianna C. Cardona, Andres Pelaez, E. C. Lawrence, Allan D. Ramirez, Seth D. Force, Allan D. Kirk, Christian P. Larsen, and David C. Neujahr. “Macrophage Gene Expression Is Skewed toward M1 Polarization in Acute Rejection Following Human Lung Transplantation.” In American Journal of Transplantation, 9:213–14. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Newell, Kenneth A., Adam Asare, Allan D. Kirk, Trang Gisler, Manikkam Suthanthiran, William J. Burlingham, Katarzyna Bourcier, William H. Marks, Laurence A. Turka, and Vicki Seyfert-Margolis. “Peripheral B Cell Markers Identify Tolerant Renal Transplant Recipients.” In American Journal of Transplantation, 9:723–723. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Page, Andrew, Kelly Hamby, Allan Kirk, Christian Larsen, and Leslie Kean. “The Impact of MHC-Disparity on Alloreactive CD8+T Cell Precursor Frequency: Unexpected Similarities between Unrelated and Haplo-Identical Transplant Pairs.” In American Journal of Transplantation, 9:486–486. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Reisman, Natalie M., Maylene E. Wagener, Allan D. Kirk, Christian P. Larsen, and Mandy L. Ford. “Anti-LFA-1 and CTLA-4 Ig Synergize in Attenuating Donor-Reactive CD4+and CD8+T Cell Responses and in Prolonging Graft Survival.” In American Journal of Transplantation, 9:539–539. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Turgeon, Nicole A., Jose G. Avila, Avinash Agarwal, Jose A. Cano, Elizabeth B. Holbrook, Marti H. Sears, Patrick H. Bowen, Allan D. Kirk, Thomas C. Pearson, and Christian P. Larsen. “Development of a Novel Immunosuppressive Regimen To Facilitate Single Donor Islet Cell Transplantation Using Efalizumab.” In American Journal of Transplantation, 9:321–321. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Turner, Alexandra P., Timothy Weaver, Raul Badell, Jose Cano, Jose Avila, Pamela Turner, Frank Leopardi, Elizabeth Strobert, Christian P. Larsen, and Allan D. Kirk. “LFA-3-Ig (Alefacept) Prolongs Allograft Survival by Targeting Costimulation Blockade Resistant T Effector Memory Cells in Non-Human Primate Islet Transplantation.” In American Journal of Transplantation, 9:237–237. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Turner, Alexandra P., Virginia Shaffer, Christine Martens, Pamela Turner, Rose Hendrix, Linda Stempora, Shivaprakash Gangappa, Allan D. Kirk, and Christian P. Larsen. “Rapamycin Enhances the Magnitude and Quality of Viral-Specific CD8+T Cell Responses to Vaccinia Virus Vaccination in the Rhesus Macaque.” In American Journal of Transplantation, 9:623–623. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Wang, Xiaoping, He Xu, Pu Wang, Ping Yun, Zidong Liu, and Allan D. Kirk. “Study Evaluating Efficacy of a Novel Rabbit Anti-Human Leukocyte Polyclonal Antibody in Combination with Rituximab in a Primate Model of Renal and Skin Allotransplantation.” In American Journal of Transplantation, 9:367–367. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Xu, He, Qiansheng Li, Yong Jiang, Xiaoping Wang, and Allan D. Kirk. “TNF-alpha Pathway Plays a Critical Role in Regulating CXCL11 and IP-10 Production in an Initial Allogeneic Human Monocyte-Endothelial Cell Interaction.” In American Journal of Transplantation, 9:338–338. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Xu, He, Qiansheng Li, Yong Jiang, and Allan D. Kirk. “Cytokine Release Profiling in Nonhuman Primates Treated with a Novel Polyclonal Rabbit Anti-Human Leukocyte Antibody.” In American Journal of Transplantation, 9:664–664. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Xu, He, Yusong Fang, Liangming Zhu, Yong Jiang, and Allan D. Kirk. “Targeting and Modulating Human Lymphocytes and Monocytes with a Novel Polyclonal Rabbit Anti-Human Leukocyte Antibody.” In American Journal of Transplantation, 9:319–319. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Miller, Weston, Caleb E. Wheeler, Angela Panoskaltsis-Mortari, Allan Kirk, Christian P. Larsen, Bruce R. Blazar, and Leslie Kean. “Prevention of Acute GvHD during Haplo-BMT: Evaluating the Efficacy of T-Cell Costimulation Blockade Using a Novel Rhesus Macaque Transplant Model.” In Blood, 112:1207–1207. AMER SOC HEMATOLOGY, 2008.
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  - Rigby, Mark R., Alison Trexler, Hameeda Bello-Laborn, Leslie Kean, Allan D. Kirk, Thomas C. Pearson, and Christian P. Larsen. “Blocking CD28 or LFA-1, but not CD154, signaling results in abortive activation of antigen-stimulated T cells.” In Diabetes, 57:A351–52. AMER DIABETES ASSOC, 2008.
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  - Agarwal, A., A. Meetha, K. E. Kokko, N. A. Turgeon, P. L. Tso, K. A. Newell, T. C. Pearson, C. P. Larsen, and A. D. Kirk. “Impact of rabbit anti-thymocyte globulin induction therapy on reactivation of BK virus in renal transplant recipients.” In American Journal of Transplantation, 8:460–460. BLACKWELL PUBLISHING, 2008.
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  - Agarwal, A., L. Y. Shen, K. E. Kokko, R. A. Bray, H. M. Gebel, T. C. Pearson, C. P. Larsen, and A. D. Kirk. “Relevance of donor specific antibodies in simultaneous liver kidney transplantation.” In American Journal of Transplantation, 8:378–378. BLACKWELL PUBLISHING, 2008.
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  - Bearden, Christopher M., P. L. Tso, N. A. Turgeon, K. Ogan, T. C. Pearson, A. D. Kirk, C. P. Larsen, and K. A. Newell. “Laparoscopic donor nephrectomy: Multiple arteries are not a predictor of recipient outcomes.” In American Journal of Transplantation, 8:457–457. BLACKWELL PUBLISHING, 2008.
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  - Charafeddine, Ali H., Meral Gunay-Aygun, Timothy A. Weaver, Dawn M. Maynard, Avi Agarwal, Neal Lwakoshi, William A. Gahl, and Allan D. Kirk. “Compartmentalization of platelet derived CD154: Implications for clinical correlation.” In American Journal of Transplantation, 8:494–494. BLACKWELL PUBLISHING, 2008.
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  - Cherikh, Wida S., Douglas W. Hanto, and Allan D. Kirk. “The effect of sirolimus on de novo cancer after kidney transplantation: An OPTN database analysis.” In American Journal of Transplantation, 8:257–257. BLACKWELL PUBLISHING, 2008.
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  - Cravedi, P., O. Cheng, A. D. Kirk, D. Kleiner, and R. B. Mannon. “Discovering what the eye can't see: Gene expression in baseline biopsies of kidney allografts.” In American Journal of Transplantation, 8:336–336. BLACKWELL PUBLISHING, 2008.
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  - Ford, Mandy L., Craig M. Steeds, Maylene E. Wagener, Allan D. Kirk, and Christian P. Larsen. “CD8+ memory T cells specific for a single surrogate minor antigen are sufficient to inhibit transplant tolerance induced by CTLA-4 ig and anti-CD154.” In American Journal of Transplantation, 8:293–293. BLACKWELL PUBLISHING, 2008.
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  - Ford, Mandy L., Maylene E. Wagener, Allan D. Kirk, and Christian P. Larsen. “Linked antigen-specific high frequency T cells augment effector activity but not accumulation of low frequency CD8+ donor-reactive T cell responses following CD28/CD154 blockade.” In American Journal of Transplantation, 8:418–418. BLACKWELL PUBLISHING, 2008.
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  - Newell, Kenneth A., Adam Asare, Allan D. Kirk, Trang Gisler, Manikkam Suthanthiran, William Burlingham, William Marks, Laurence Turka, and Vicki Seyfert-Margolis. “A unique B cell signature associated with operational tolerance.” In American Journal of Transplantation, 8:316–316. BLACKWELL PUBLISHING, 2008.
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  - Rigby, M. R., A. M. Trexler, H. Bello-Labom, A. D. Kirk, T. C. Pearson, L. Kean, and C. P. Larsen. “Antagonism of signaling through CD28 or LFA-1, but not CD154, result in abortive activation of antigen-stimulated T cells.” In American Journal of Transplantation, 8:624–624. BLACKWELL PUBLISHING, 2008.
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  - Rigby, M. R., H. Bello-Laborn, A. M. Trexler, L. Kean, A. D. Kirk, T. C. Pearson, and C. P. Larsen. “Tregs undergo basal proliferation that is dependant on CD28 : B7, but not CD154 : CD40, signaling which can be accentuated by self-peptide.” In American Journal of Transplantation, 8:625–26. BLACKWELL PUBLISHING, 2008.
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  - Rigby, M. R., K. Kokko, N. Turgeon, M. Sears, P. H. Bowen, J. Avila, E. Holbrook, A. D. Kirk, T. C. Pearson, and C. P. Larsen. “Islet cell transplantation using surgical cannulation of the portal vein followed by delayed conversion to a MMF and tacrolimus immunosuppressive regimen.” In American Journal of Transplantation, 8:431–32. BLACKWELL PUBLISHING, 2008.
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  - Russell, Maria C., Kenneth Cardona, Virginia L. Oliva, Alexandra P. Turner, Jose Cano, Jose Avila, Wanhong Jiang, et al. “A novel costimulation blockade regimen for engraftment and function of allogeneic islets in diabetic rhesus macaques.” In American Journal of Transplantation, 8:228–29. BLACKWELL PUBLISHING, 2008.
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  - Shen, L. Y., A. Agarwal, N. A. Turgeon, C. P. Larsen, T. C. Pearson, R. A. Bray, H. M. Gebel, A. D. Kirk, and K. E. Kokko. “Combined liver-kidney transplantation across a positive flow crossmatch: A cause for concern?” In American Journal of Transplantation, 8:337–337. BLACKWELL PUBLISHING, 2008.
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  - Shen, L. Y., S. Kuppachi, N. A. Turgeon, T. C. Pearson, C. P. Larsen, and A. D. Kirk. “Influence of donor type on elderly kidney transplant survival and allograft function.” In American Journal of Transplantation, 8:531–32. BLACKWELL PUBLISHING, 2008.
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  - Singh, Kimberly A., Robert Kampen, and Allan D. Kirk. “Renal tubule cell derived M-CSF is a local informant of renal damage and potentates monocyte recruitment and activation.” In American Journal of Transplantation, 8:575–575. BLACKWELL PUBLISHING, 2008.
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  - Weaver, T. A., A. H. Charafeddine, A. Agarwal, F. Leopardi, R. Kampen, M. F. Starost, C. P. Larsen, and A. D. Kirk. “Targeting of costimulation blockade resistant T effector memory (TEM) cells in non-human primate renal transplantation with LFA-3-Ig (alefacept) prolongs allograft survival.” In American Journal of Transplantation, 8:204–5. BLACKWELL PUBLISHING, 2008.
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  - Weaver, Timothy A., Ali H. Charafeddine, Frank V. Leopardi, Avinash Agarwal, Scott D. Batty, John M. Williams, Sharon R. Nahil, and Allan D. Kirk. “Pre-clinical assessment of genz-29155, a novel small molecule inhibitor of apoptosis with anti-rejection effects in non-human primates.” In American Journal of Transplantation, 8:229–229. BLACKWELL PUBLISHING, 2008.
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  - Chamberlain, Christine E., Julie Peretti, Tracy Cropper, Liz Hale, Allan D. Kirk, and Roslyn B. Mannon. “Is it all for the better? Clarifying the impact of cinacalcet in post kidney transplant hyperparathyroidism.” In American Journal of Transplantation, 7:362–362. BLACKWELL PUBLISHING, 2007.
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  - Cheng, Orlena H., Robert L. Kampen, David E. Kleiner, Allan D. Kirk, and Roslyn B. Mannon. “Gloms away! The molecular signature of transplant glomerulopathy (TG).” In American Journal of Transplantation, 7:259–259. BLACKWELL PUBLISHING, 2007.
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  - Xu, Biying, Elizabeth Ford, Sean Crawford, Robert Kampen, and Allan D. Kirk. “Soluble CD154 (sCD154) in renal transplantation.” In American Journal of Transplantation, 7:339–339. BLACKWELL PUBLISHING, 2007.
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  - Alemozaffar, Mehrdad, Alexander Gorbach, Neil Kansal, Nadeem N. Dhanani, Fred Gage, Allan Kirk, Eric Elster, and Peter A. Pinto. “618: Intraoperative Infrared Imaging to Assess Segmental Renal Perfusion: A Model for Renal Transplantation and Nephron Sparing Surgery.” In Journal of Urology, 177:207–207. Ovid Technologies (Wolters Kluwer Health), 2007. https://doi.org/10.1016/s0022-5347(18)30858-9.
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  - Dalakas, Marinos, Goran Rakocevic, Beverly McElroy, Mohammad Salajegheh, Michael H. Love, Joseph Shrader, Ellen Levy, and Allan D. Kirk. “Alemtuzumab (CAMPATH 1-H) therapy in sporadic inclusion body myositis (sIBM): A treatment trial in patients with established natural history data.” In Neurology, 68:A361–A361. LIPPINCOTT WILLIAMS & WILKINS, 2007.
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  - Dalakas, Marinos C., Goran Rakocevic, Beverly McElroy, Mohammad K. Salaftheh, Jens Schmidt, Michael Harris-Love, Joseph Shrader, Ellen Levy, and Allen D. Kirk. “Alemtuzumab (CAMPATH 1-H) therapy in sporadic inclusion body myositis (sIBM) Alters disease progression and suppresses endomysial inflammation.” In Annals of Neurology, 62:S60–61. WILEY-LISS, 2007.
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  - Dhanireddy, Kiran K., David A. Bruno, Sruti Shiva, Frank V. Leopardi, Xiaojie Zhang, Mark Gladwin, and Allan D. Kirk. “Nitrite, a hypoxia selective nitric oxide donor, limits renal ischemia-reperfusion injury in non-human primates.” In Journal of the American College of Surgeons, 203:S31–S31. Ovid Technologies (Wolters Kluwer Health), 2006. https://doi.org/10.1016/j.jamcollsurg.2006.05.076.
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  - Dhanireddy, Kiran K., David A. Bruno, Xiaojie Zhang, Frank V. Leopardi, Lynt B. Johnson, and Allan D. Kirk. “Alefacept (LFA3-Ig), portal venous donor specific transfusion (PVDST), and sirolimus prolong renal allograft survival in non-human primates.” In Journal of the American College of Surgeons, 203:S92–S92. Ovid Technologies (Wolters Kluwer Health), 2006. https://doi.org/10.1016/j.jamcollsurg.2006.05.240.
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  - Crane, N. J., N. S. Kansal, N. Dhanani, M. Alemozaffar, A. D. Kirk, P. A. Pinto, E. A. Elster, S. W. Huffman, and I. W. Levin. “Visual enhancement of laparoscopic nephrectomies using the 3-CCD camera.” In Proceedings of Spie the International Society for Optical Engineering, Vol. 6081, 2006. https://doi.org/10.1117/12.663940.
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  - Bruno, D. A., O. Cheng, D. A. Hale, K. Dhanireddy, A. D. Kirk, E. O. Major, and R. B. Mannon. “Limiting overimmunosuppression post-transplant: The role of BK polyoma viral monitoring.” In American Journal of Transplantation, 5:254–254. BLACKWELL PUBLISHING, 2005.
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  - Dhanireddy, K. K., H. Xu, D. A. Bruno, X. Zhang, F. V. Leopardi, L. B. Johnson, D. A. Hale, and A. D. Kirk. “Pretransplant portal venous donor specific transfusion in conjunction with sirolimus prolongs renal allograft survival in non-human primates.” In American Journal of Transplantation, 5:420–420. BLACKWELL PUBLISHING, 2005.
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  - Elster, E. A., C. Chamberlin, R. B. Mannon, S. J. Swanson, A. D. Kirk, and D. A. Hale. “Three-year experiernce with alemtuzumab induction.” In American Journal of Transplantation, 5:569–569. BLACKWELL PUBLISHING, 2005.
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  - Mannon, R. B., S. Hoffmann, O. Cheng, R. Kampen, D. Kleiner, B. Becker, and A. D. Kirk. “The molecular signature of calcineurin inhibitor (CNI) toxicity: Death to the graft!.” In American Journal of Transplantation, 5:327–327. BLACKWELL PUBLISHING, 2005.
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  - Berhane, D., R. B. Mannon, S. J. Swanson, D. A. Hale, A. D. Kirk, and D. E. Kleiner. “Quantitative assessment of glomerular infiltrates in chronic allograft glomerulopathy.” In Modern Pathology, 18:265A-265A. NATURE PUBLISHING GROUP, 2005.
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  - Mannon, Roslyn B., David Bruno, Orlena H. Cheng, Douglas Hale, Allan D. Kirk, and Eugene Major. “The highs and lows of post-transplant immunosuppression: The role of BK polyoma viral monitoring.” In Journal of Neurovirology, 14:25–25. SPRINGER, 2005.
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  - Dhanireddy, K. K., H. Xu, X. J. Zhang, F. V. Leopardi, L. B. Johnson, D. A. Hale, and A. D. Kirk. “Pretransplant portal venous adoptive transfer in conjunction with sirolimus prolongs renal allograft survival in non-human primates.” In Journal of the American College of Surgeons, 199:S96–97. ELSEVIER SCIENCE INC, 2004.
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  - Pearl, J. P., H. Xu, and A. D. Kirk. “Nonhuman primates have a high proportion of regulatory T-cells after lymphocyte depletion.” In Journal of the American College of Surgeons, 199:S94–S94. ELSEVIER SCIENCE INC, 2004.
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  - Cendales, L. C., D. Kleiner, M. A. Eckhaus, R. Kampen, and A. D. Kirk. “Characterization of human and non-human primate composite tissue allograft rejection.” In American Journal of Transplantation, 4:341–341. BLACKWELL MUNKSGAARD, 2004.
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  - Cendales, L. C., X. J. Zhang, H. Xu, J. Bacher, and A. D. Kirk. “Composite tissue allotransplantation: Development of a non-human primate model.” In American Journal of Transplantation, 4:508–508. BLACKWELL MUNKSGAARD, 2004.
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  - Chamberlain, C. E., E. Elster, D. Hale, A. D. Kirk, C. E. Daniels, and R. B. Mannon. “Weaker and weaker still: Steroid avoidance does not prevent bone loss following kidney transplantation.” In American Journal of Transplantation, 4:566–566. BLACKWELL MUNKSGAARD, 2004.
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  - Dhanireddy, K. K., H. Xu, E. H. Preston, J. P. Pearl, F. V. Leopardi, L. B. Johnson, and A. D. Kirk. “Alloantibody develops coincident with rejection of skin and renal allografts in non-human primates treated with the anti CD-154 monoclonal antibody IDEC-131 combined with donor specific transfusion (DST) and sirolimus.” In American Journal of Transplantation, 4:332–332. BLACKWELL MUNKSGAARD, 2004.
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  - Elster, E. A., C. Chamberlain, C. Salaita, A. D. Kirk, D. Hale, and R. B. Mannon. “Steroids have no calories: Weight gain post transplantation is not prevented by steroid avoidance.” In American Journal of Transplantation, 4:545–545. BLACKWELL MUNKSGAARD, 2004.
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  - Elster, E. A., D. Hale, L. B. Cendales, D. Kleiner, M. Ring, B. Niles, S. J. Swanson, R. B. Mannon, and A. D. Kirk. “Correlation of renal resistance index and biopsy proven chronic allograft nephropathy: A part of the general transplant physical exam.” In American Journal of Transplantation, 4:485–485. BLACKWELL MUNKSGAARD, 2004.
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  - Hoffmann, S. C., J. P. Pearl, D. A. Hale, R. B. Mannon, S. J. Swanson, and A. D. Kirk. “Early allograft rejection is mediated by CD3+CD4+CD45RA-CD62L-memory cells following alemtuzumab depletion.” In American Journal of Transplantation, 4:413–413. BLACKWELL MUNKSGAARD, 2004.
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  - Hoffmann, S. C., R. L. Kampen, J. P. Pearl, D. A. Hale, L. M. Jacobson, D. E. Kleiner, R. B. Mannon, et al. “The new standard of care: Alemtuzumab induction with Tacrolimus and Sirolimus maintenance immunosuppression to limit acute and chronic allograft rejection.” In American Journal of Transplantation, 4:332–332. BLACKWELL MUNKSGAARD, 2004.
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  - Hoffmann, S., L. M. Jacobson, R. J. Muehrer, A. D. Kirk, S. Knechtle, and B. N. Becker. “Distinct fibrosis patterns characterize Campath-1H plus rapamycin versus traditional therapy with calcineurin inhibition.” In American Journal of Transplantation, 4:160–160. BLACKWELL MUNKSGAARD, 2004.
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  - Mannon, R. B., D. Post, R. Kowalski, A. D. Kirk, D. Hale, and J. Britz. “Assessing immune reconsitution: Monitoring lymphocyte immune function following depletional therapy using the ImmunKnow (TM) assay.” In American Journal of Transplantation, 4:222–222. BLACKWELL MUNKSGAARD, 2004.
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  - Mannon, R. B., O. H. Cheng, S. C. Hoffmann, A. D. Kirk, and G. Grottendorst. “Predicting the future: Connective tissue growth factor (CTGF), a surrogate for the development of chronic allograft nephropathy (CAN) in man.” In American Journal of Transplantation, 4:276–276. BLACKWELL MUNKSGAARD, 2004.
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  - Mannon, R. B., S. C. Hoffman, R. Kampen, O. H. Cheng, D. Hale, A. D. Kirk, and D. E. Kleiner. “Death and destruction: The molecular and cellular events of polyomavirus nephropathy (PVN).” In American Journal of Transplantation, 4:307–307. BLACKWELL MUNKSGAARD, 2004.
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  - Pearl, J. P., H. Xu, K. L. Christopher, F. Leopardi, E. Preston, L. Cendales, D. Hale, and A. D. Kirk. “Aggressive lymphocyte depletion does not eliminate immune memory.” In American Journal of Transplantation, 4:302–302. BLACKWELL MUNKSGAARD, 2004.
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  - Pearl, J. P., J. Parris, K. L. McCoy, S. C. Hoffman, K. L. Christopher, H. Xu, R. B. Mannon, D. Hale, S. J. Swanson, and A. D. Kirk. “Immunocompetent memory T-cells are the dominant cell type following antibody-mediated T-cell depletion and may be a barrier to achieving tolerance.” In American Journal of Transplantation, 4:303–303. BLACKWELL MUNKSGAARD, 2004.
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  - Xu, H., K. K. Dhanireddy, and A. D. Kirk. “Monocytes act as a bridge between T cells and allogeneic endothelial cells via IFN gamma-dependent processes.” In American Journal of Transplantation, 4:538–538. BLACKWELL MUNKSGAARD, 2004.
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  - Xu, H., X. J. Zhang, F. Leopradi, R. B. Mannon, and A. D. Kirk. “Human platelet-derived CD154 plays an important role in initiating allograft rejetion.” In American Journal of Transplantation, 4:581–581. BLACKWELL MUNKSGAARD, 2004.
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  - Xu, H., X. J. Zhang, R. B. Mannon, and A. D. Kirk. “A nuclear factor-kappa B inhibitor, BAY 11-7082, inhibits interactions between human endothelial cells, T-cells, and monocytes.” In American Journal of Transplantation, 4:286–286. BLACKWELL MUNKSGAARD, 2004.
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  - Xu, H., X. J. Zhang, and A. D. Kirk. “Monocytes engulf endothelial membranes via a scavenger receptor, and scavenger receptor blockade prevents monocyte activation.” In American Journal of Transplantation, 4:393–393. BLACKWELL MUNKSGAARD, 2004.
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  - Pearl, J. P., M. Roederer, and A. D. Kirk. “Cyclosporine a uniquely inhibits the function of depletion-resistant memory cells.” In Journal of the American College of Surgeons, 197:S90–S90. ELSEVIER SCIENCE INC, 2003.
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  - Hirshberg, B., E. H. Preston, H. Xu, M. G. Wysoki, Z. Neeman, D. Bunnell, S. Soleimanpour, D. A. Hale, A. D. Kirk, and D. M. Harlan. “Rabbit anti-thymocyte globulin induction and sirolmius monotherapy supports prolonged islet allograft function in a nonhuman primate islet transplantation model.” In Cell Transplantation, 12:143–44. COGNIZANT COMMUNICATION CORP, 2003.
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  - Hirshberg, B., K. I. Rother, J. Lee, J. Gaglia, K. Hines, N. Patterson, E. J. Reed, et al. “Islet transplantation: The NIH experience.” In Diabetes, 51:A33–A33. AMER DIABETES ASSOC, 2002.
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  - Rother, K. I., A. E. Sumner, B. Hirshberg, J. Lee, J. Gaglia, K. Hines, N. Patterson, E. J. Read, A. D. Kirk, and D. M. Harlan. “Assessment of insulin and C-peptide secretion after islet transplantation.” In Diabetes, 51:A33–A33. AMER DIABETES ASSOC, 2002.
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  - Kleiner, D. E., S. M. Hewitt, D. A. Hale, R. B. Mannon, S. J. Swanson, and A. D. Kirk. “Unusual immunologic response to renal allografts in patients receiving CAMPATH-1H as a sole immunosuppressant.” In Modern Pathology, 15:278A-278A. NATURE PUBLISHING GROUP, 2002.
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  - Kleiner, D. E., S. M. Hewitt, D. A. Hale, R. B. Mannon, S. J. Swanson, and A. D. Kirk. “Unusual immunologic response to renal allografts in patients receiving CAMPATH-1H as a sole immunosuppressant.” In Laboratory Investigation, 82:278A-278A. NATURE PUBLISHING GROUP, 2002.
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  - Hoffmann, S. C., E. M. Stanley, E. D. Cox, N. Craighead, S. P. Perfetto, D. M. Harlan, A. D. Kirk, and P. J. Blair. “The polymorphism at-330 in the interleukin-2 gene results in a significant increase in IL-2 protein following co-stimulation of peripheral blood lymphocytes with anti-CD3/CD28.” In Faseb Journal, 15:A1055–A1055. FEDERATION AMER SOC EXP BIOL, 2001.
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  - Hoffmann, S. C., E. M. Stanley, E. D. Cox, B. S. DiMercurio, D. E. Koziol, D. M. Harlan, A. D. Kirk, and P. J. Blair. “Correlation of cytokine gene polymorphic inheritance and in vitro cytokine production in anti-CD3/CD28 stimulated peripheral blood lymphocytes.” In Faseb Journal, 15:A666–A666. FEDERATION AMER SOC EXP BIOL, 2001.
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  - Leitman, S. F., A. D. Kirk, D. S. Gladden, and J. Kopp. “Plasma exchange in the treatment of recurrent focal segmental glomerulosclerosis (FSGS) following renal transplant.” In Transfusion, 40:54S-55S. AMER ASSOC BLOOD BANKS, 2000.
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  - Abbott, K. C., J. D. Oliver, C. W. Ko, A. D. Kirk, S. M. Polly, C. A. Jones, and L. Y. Agodoa. “Patient and renal allograft survival in patients seropositive for human immunodeficiency virus infection at transplantation: Data from the UNOS/USRDS database.” In Transplantation, 69:S217–S217. LIPPINCOTT WILLIAMS & WILKINS, 2000.
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  - Abbott, K. C., J. D. Oliver, C. W. Ko, A. D. Kirk, and L. Y. Agodoa. “Aseptic necrosis after cadaveric renal transplantation: Data from the UNOS/USRDS database.” In Transplantation, 69:S323–S323. LIPPINCOTT WILLIAMS & WILKINS, 2000.
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  - Abbott, K. C., J. D. Oliver, C. W. Ko, A. D. Kirk, and Y. Agodoa. “Fractures after cadaveric renal transplantation: Data from the UNOS/USRDS database.” In Transplantation, 69:S288–S288. LIPPINCOTT WILLIAMS & WILKINS, 2000.
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  - Batty, D. S., S. J. Swanson, S. M. Polly, J. D. Oliver, D. K. Oliver, C. W. Ko, A. D. Kirk, L. Y. Agodoa, and K. C. Abbott. “Impact of recipient and donor hepatitis C virus infection status on outcomes after renal transplantation: Data from the UNOS/USRDS database.” In Transplantation, 69:S135–S135. LIPPINCOTT WILLIAMS & WILKINS, 2000.
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  - Becker, B. N., L. M. Jacobson, D. A. Hullett, Y. T. Becker, T. D. Oberley, and A. D. Kirk. “Type 2 angiotensin II receptor mRNA expression in human renal allografts is associated with chronic rejection.” In Transplantation, 69:S400–S400. LIPPINCOTT WILLIAMS & WILKINS, 2000.
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  - Elster, E. A., H. Xu, L. C. Burkly, J. D. Berning, R. E. Baumgartner, R. L. Kampen, N. B. Patterson, D. K. Tadaki, D. M. Harlan, and A. D. Kirk. “Primary skin allograft acceptance with anti-CD154 in a non-human primate model.” In Transplantation, 69:S239–S239. LIPPINCOTT WILLIAMS & WILKINS, 2000.
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  - Swanson, S. J., K. C. Abbott, J. D. Oliver, C. W. Ko, A. D. Kirk, and L. Y. Agodoa. “Impact of donor and recipient factors on graft survival after cadaveric renal transplantation: Data from the UNOS/USRDS database.” In Transplantation, 69:S262–63. LIPPINCOTT WILLIAMS & WILKINS, 2000.
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  - Xu, H., D. K. Tadaki, P. J. Blair, D. M. Harlan, and A. D. Kirk. “Porcine endothelium costimulates human T cells in the absence of human antigen presenting cells (APCs).” In Transplantation, 69:S258–S258. LIPPINCOTT WILLIAMS & WILKINS, 2000.
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  - Xu, H., F. Arnaud, D. K. Tadaki, L. C. Burkly, D. M. Harlan, and A. D. Kirk. “Human platelets activate porcine endothelial cells through a CD154 dependent mechanism.” In Transplantation, 69:S384–S384. LIPPINCOTT WILLIAMS & WILKINS, 2000.
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  - Elster, Eric A., Patrick J. Blair, and Allan D. Kirk. “Potential of costimulation‐based therapies for composite tissue allotransplantation.” In Microsurgery, 20:430–34. Wiley, 2000. https://doi.org/10.1002/1098-2752(2000)20:8<430::aid-micr14>3.3.co;2-b.
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  - Kenyon, Norma S., Maria Chatzipetrou, Michele Masetti, Alessandra Ranuncoli, Maria Oliveira, Joseph L. Wagner, Allan D. Kirk, David M. Harlan, Linda C. Burkly, and Camillo Ricordi. “LONG-TERM INTRAHEPATIC ISLET ALLOGRAFT SURVIVAL IN NON-HUMAN PRIMATES TREATED WITH ANTI-CD154 MONOTHERAPY.” In Transplantation, 67:S550–S550. Ovid Technologies (Wolters Kluwer Health), 1999. https://doi.org/10.1097/00007890-199905150-00057.
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  - Baumgartner, Roxanne E., Noelle B. Patterson, Justin Berning, Linda Burkly, Rhonda Germond, David M. Harlan, Robert Kampen, Douglas K. Tadaki, Sharda G. Sabnis, and Allan D. Kirk. “RHESUS RENAL ALLOGRAFTS CONTAIN NON-DESTRUCTIVE ACTIVATED LYMPHOCYTIC INFILTRATES FOLLOWING ANTI-CD154 THERAPY.” In Transplantation, 67:S63–S63. Ovid Technologies (Wolters Kluwer Health), 1999. https://doi.org/10.1097/00007890-199904150-00254.
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  - Blair, P. J., J. L. Riley, D. M. Harlan, T. E. Francomano, S. J. Perfetto, A. D. Kirk, and C. H. June. “COLIGATION OF CD40L (CD154) AND CD3 RESULTS IN CD4+ T CELL ACTIVATION AND THE INDUCTION OF APOPTOSIS.” In Transplantation, 67:S131–S131. Ovid Technologies (Wolters Kluwer Health), 1999. https://doi.org/10.1097/00007890-199904150-00528.
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  - Burlingham, W. J., P. J. O’Connell, J. D. Pirsch, B. N. Becker, A. D. Kirk, L. M. Jacobson, L. T. Chin, et al. “STABILITY OF THE TOLERANCE PHENOTYPE AFTER WITHDRAWAL OF IMMUNOSUPPRESSIVE DRUG THERAPY: INFLUENCE OF LOCAL AND GENETIC FACTORS INFLUENCING TNFα AND TGFβ EXPRESSION.” In Transplantation, 67:S69–S69. Ovid Technologies (Wolters Kluwer Health), 1999. https://doi.org/10.1097/00007890-199904150-00278.
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  - Tadaki, Douglas K., Amanda Williams, Allan D. Kirk, Kelvin P. Lee, and David M. Harlan. “CLONING OF PORCINE CD80 AND CHARACTERIZATION OF HUMAN T CELL COSTIMULATORY ACTIVITY.” In Transplantation, 67:S222–S222. Ovid Technologies (Wolters Kluwer Health), 1999. https://doi.org/10.1097/00007890-199904150-00886.
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  - Kenyon, N. S., M. Chatzipetrou, M. Masetti, A. Ranuncoli, M. Oliveira, J. L. Wagner, A. D. Kirk, D. M. Harlan, L. C. Burkly, and C. Ricordi. “Engraftment and long-term survival of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154 (hu5c8).” In Diabetes, 48:A59–A59. AMER DIABETES ASSOC, 1999.
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