Allison Elizabeth Ashley-Koch

Journal article Mol Psychiatry · August 2010 Featured Publication This longitudinal study examined the relationship between 2-year change in white matter hyperintense lesion (WML) volume and polymorphisms in genes coding for the angiotensin-II type 1 and type 2 receptors, AGTR1 A1166C and AGTR2 C3123A, respectively. 137 ... Full text Link to item Cite

Genetic variants in SLC9A9 are associated with measures of attention-deficit/hyperactivity disorder symptoms in families.

Journal article Psychiatr Genet · April 2010 Featured Publication OBJECTIVE: A family was previously identified that cosegregates a pericentric inversion, inv(3)(p14 : q21), with an early-onset developmental condition, characterized by impulsive behavior and intellectual deficit. The inversion breakpoints lie within DOCK ... Full text Link to item Cite

Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study.

Journal article Am J Hematol · January 2010 Featured Publication We conducted a genome-wide association study (GWAS) to discover single nucleotide polymorphisms (SNPs) associated with the severity of sickle cell anemia in 1,265 patients with either "severe" or "mild" disease based on a network model of disease severity. ... Full text Link to item Cite

Effects of postnatal parental smoking on parent and teacher ratings of ADHD and oppositional symptoms.

Journal article J Nerv Ment Dis · June 2009 Featured Publication To assess the effects of postnatal parental smoking on subsequent parent and teacher ratings of DSM-IV attention deficit hyperactivity disorder (ADHD) symptoms and oppositional behaviors in children diagnosed with ADHD and their siblings. Children between ... Full text Link to item Cite

Multiple rare SAPAP3 missense variants in trichotillomania and OCD.

Journal article Mol Psychiatry · January 2009 Featured Publication Full text Link to item Cite

Further evidence for a maternal genetic effect and a sex-influenced effect contributing to risk for human neural tube defects.

Journal article Birth Defects Res A Clin Mol Teratol · October 2008 Featured Publication BACKGROUND: Neural tube defects (NTDs), including spina bifida and anencephaly, are the second most common birth defect with an incidence of 1/1000. Genetic factors are believed to contribute to NTD risk and family-based studies can be useful for identifyi ... Full text Link to item Cite

Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease.

Journal article Blood · June 15, 2008 Featured Publication Up to 30% of adult patients with sickle cell disease (SCD) will develop pulmonary hypertension (pHTN), a complication associated with significant morbidity and mortality. To identify genetic factors that contribute to risk for pHTN in SCD, we performed ass ... Full text Link to item Cite

Investigation of potential gene-gene interactions between APOE and RELN contributing to autism risk.

Journal article Psychiatr Genet · August 2007 Featured Publication BACKGROUND: Several candidate gene studies support RELN as susceptibility gene for autism. Given the complex inheritance pattern of autism, it is expected that gene-gene interactions will exist. A logical starting point for examining potential gene-gene in ... Full text Link to item Cite

SLITRK1 mutations in trichotillomania.

Journal article Mol Psychiatry · October 2006 Featured Publication Full text Link to item Cite