Journal articleJ Surg Res · July 2026
INTRODUCTION: The minority tax is an understudied phenomenon by which underrepresented in medicine (URiM) physicians are more often responsible for nonpromotable activities: mentorship, education, outreach, and committee service. This review aims to summar ...
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Journal articleJMIR Perioper Med · May 4, 2026
BACKGROUND: Artificial intelligence (AI) models are being increasingly integrated into clinical care. Moreover, the availability of publicly accessible AI resources makes them attractive to patients seeking clinical information. Little is known regarding t ...
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ConferenceAnn Surg Oncol · February 2026
BACKGROUND: Veterans Affairs (VA) patients participate within the largest USA equal-access healthcare system, though still experience cancer mortality disparities by social determinants. The Social Vulnerability Index (SVI)-measuring community poverty, min ...
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Journal articleAnn Surg Oncol · January 2026
BACKGROUND: Telehealth has emerged as a promising solution to address access gaps in cancer care, particularly for complex conditions such as hepatopancreatobiliary (HPB) cancers. Despite the broader adoption of telemedicine in oncology, HPB cancers remain ...
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Journal articleHepatology · September 1, 2025
BACKGROUND AND AIMS: Patients with HCC meeting United Network for Organ Sharing (UNOS)-downstaging (DS) criteria have excellent post-liver transplantation (LT) outcomes. Studies on HCC beyond UNOS-DS criteria ("All-Comers" [AC]) have been limited by small ...
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Journal articleSurgical Oncology Insight · March 1, 2025
Background: Gallbladder cancer (GBC) portends a poor prognosis, and guidelines recommend radical cholecystectomy for patients with T1b and greater disease. We evaluated prognostic factors for T2 and T3 GBC among a contemporary cohort. Methods: The National ...
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Journal articleAnn Surg Oncol · December 2024
Social media has become omnipresent in society, especially given that it enables the rapid and widespread communication of news, events, and information. Social media platforms have become increasingly used by numerous surgical societies to promote meeting ...
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Journal articleCancer · November 15, 2024
With the proliferation of cancer research based on large databases, misalignment of research questions and data set capabilities is inevitable. Nationally maintained databases are appealing to cancer researchers because of the ease of access to large amoun ...
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Journal articleAnn Surg Oncol · November 2024
BACKGROUND: The Centers for Medicare and Medicaid Services (CMS) price transparency rule tries to facilitate cost-conscious decision-making. For surgical services, such as pancreaticoduodenectomy (PD), factors mediating transparency and real-world reimburs ...
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ConferenceCancer Research · September 15, 2024
AbstractLess than 20% of patients diagnosed with pancreatic cancer will present with localized disease and receive both resection and systemic therapy. Within this group of patients, actual 10-year survival ...
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Journal articleClin Oncol (R Coll Radiol) · September 2024
AIMS: Prognosis of locally advanced pancreatic cancer (LAPC) remains poor with limited therapeutic options. Radiation therapy in pancreatic cancer has been restricted by the disease's proximity to radiosensitive organs at risk (OAR). However, stereotactic ...
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Journal articleAm J Surg · July 2024
BACKGROUND: While risk-stratified post-hepatectomy pathways (RSPHPs) reduce length-of-stay, can they stratify hepatectomy patients by risk of early postoperative events. METHODS: 90-day outcomes from consecutive hepatectomies were analyzed (1/1/2017-12/31/ ...
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ConferenceJournal of Clinical Oncology · February 1, 2024
640 Background: Use of Abx was associated with worse overall survival (OS) and progression-free survival (PFS) in our real-world cohort of mUC pts treated with ICI. (ASCO 2023). We now report the effect of type of Abx on ICI outc ...
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ConferenceJournal of Clinical Oncology · February 1, 2024
678 Background: Elevated inflammatory biomarkers like the neutrophil to lymphocyte ratio (NLR) has been associated with poor prognosis in several cancers, including UC but there is limited evidence on its role as a prognostic bio ...
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ConferenceJournal of Clinical Oncology · June 1, 2023
4580 Background: Use of Abx may negatively affect outcomes with ICI, possibly due to negative impact on gut microbiota. We previously showed that in our real world cohort of 138 mUC pts, Abx use within 30 or 60 days (d) of ICI in ...
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Journal articleHPB (Oxford) · March 2023
BACKGROUND: Simultaneous resection of colorectal liver metastases (CLM) and primary colorectal cancers (CRC) is nuanced without firm rules for selection. This study aimed to identify factors associated with morbidity after simultaneous resection. METHODS: ...
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Book section · February 24, 2023
Barry W Feig. 24. Surgical. Emergencies. and. Palliative. Interventions. in. Cancer. Patients. Allison N. Martin and Brian D. Badgwell. INTRODUCTION. Oncologic emergencies have been defined as “an acute condition that is caused by cancer or ... ...
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Journal articleAnn Surg Oncol · January 2023
BACKGROUND: Patients with unplanned excision (UPE) of trunk and extremity soft tissue sarcoma (STS) present a significant management challenge for sarcoma specialists. Oncologic re-resection has been considered standard practice after UPE with positive or ...
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Journal articleAm J Surg · January 2023
BACKGROUND: The value of individual variable contributions to post-hepatectomy length of stay (LOS) are difficult to quantify within bundled care pathways. METHODS: Poisson regression and marginal effects models for prolonged post-hepatectomy LOS (>25% med ...
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Book section · 2023
Underrepresented minority patients with pancreatic cancer have differential access to cancer treatments, including clinical trials. The successful conduct and completion of clinical trials is critical to improve outcomes for patients with pancreatic cancer ...
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Journal articleSurg Open Sci · July 2022
BACKGROUND: The Kawaguchi-Gayet classification is a validated system to stratify open liver resections by complexity and postoperative complications. We hypothesized that Kawaguchi-Gayet classification could be used to create and implement risk-stratified ...
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Journal articleClin Lymphoma Myeloma Leuk · July 2021
INTRODUCTION: Daratumumab is an anti-CD38 monoclonal antibody widely used for treating patients with newly diagnosed or relapsed/refractory multiple myeloma. The subcutaneous formulation of daratumumab was developed with the purpose of minimizing the treat ...
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Journal articleJ Surg Educ · 2021
In order to maintain productivity and career advancement, Black and Brown individuals often find themselves downplaying persistent elements of bias and racism experienced in predominantly white fields. These elements are commonly reinforced by institutiona ...
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Journal articlePLoS One · 2021
BACKGROUND: Telemedicine has been rapidly adopted in the wake of the COVID-19 pandemic. There is limited work surrounding demographic and socioeconomic disparities that may exist in telemedicine utilization. This study aimed to examine demographic and soci ...
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ConferenceBlood · November 5, 2020
Background:Financial toxicity (FT) is defined as financial distress as a result of disease or treatment decisions. FT might be considered analogous to physical toxicity. Patients with high risk hematologic malignanc ...
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ConferenceBlood · November 5, 2020
Background:Financial toxicity (FT) has been consistently demonstrated to a be a major contributor to morbidity and mortality in a variety of cancers. However, the vast majority of research examining this issue has b ...
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ConferenceBlood · November 5, 2020
Introduction:Letermovir is a terminase complex inhibitor that was recently approved for prevention of cytomegalovirus (CMV) reactivation after allogeneic hematopoietic cell transplant (HCT). Its favorable side effec ...
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ConferenceCancer Research · August 15, 2020
AbstractDiffuse intrinsic pontine glioma (DIPG) and atypical teratoid/rhabdoid tumors (AT/RT) are deadly pediatric brain tumors. There is an urgent need of better therapeutics for improving survival and qual ...
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Journal articleWorld J Surg · August 2020
BACKGROUND: Preoperative assessment of geriatric-specific determinants of health may enhance perioperative risk stratification among elderly patients. This study examines effects of geriatric-specific variables on postoperative outcomes in patients undergo ...
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Journal articleJ Am Coll Surg · April 2020
BACKGROUND: Elderly patients (65 years of age and older) undergo an increasing number of operations performed annually in the US and they present with unique healthcare needs. Preventing postoperative readmission remains an important challenge to improving ...
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Journal articleBJS Open · February 2020
BACKGROUND: Child survival initiatives historically prioritized efforts to reduce child morbidity and mortality from infectious diseases and maternal conditions. Little attention has been devoted to paediatric injuries in resource-limited settings. This st ...
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Journal articleDis Colon Rectum · November 2019
BACKGROUND: Delayed initiation of adjuvant chemotherapy negatively impacts long-term survival in patients with colorectal cancer. Colorectal enhanced recovery protocols result in decreased complications and length of stay; however, the impact of enhanced r ...
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Book section · October 29, 2019
An ideal resource for written, oral, and recertifying board study, as well as an excellent reference for everyday clinical practice, Current Surgical Therapy, 13th Edition, provides trusted, authoritative advice on today's best treatment ... ...
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Journal articleAnn Thorac Surg · August 2019
BACKGROUND: Little is known about health disparities in access to low-dose computed tomography (LDCT) screening. This study hypothesized that the current capacity for LDCT screening would be exceeded by the number of at-risk individuals in Virginia. METHOD ...
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Journal articleEur Urol Focus · May 2019
BACKGROUND: The incidence of brain metastases (BM) in patients with renal cell carcinoma (RCC) is hypothesized to have increased in the last 2 decades. OBJECTIVE: To define incidence trends according to patient and clinical characteristics, to identify ris ...
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Journal articleSurg Obes Relat Dis · April 2019
BACKGROUND: Prior studies investigating racial, socioeconomic, and/or insurance disparities with regard to access to care and outcomes in bariatric surgery have been performed with varying results. OBJECTIVES: Our aim was to determine if racial or ethnic d ...
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Journal articleSurgery · February 2019
BACKGROUND: There is conflicting evidence regarding the impact of human immunodeficiency virus serostatus on trauma outcomes in low-resource settings. This study sought to evaluate the impact of human immunodeficiency virus serostatus on mortality outcomes ...
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Journal articleAm Surg · February 1, 2019
Optimal treatment for small hepatocellular carcinoma (HCC) ≤ 3 cm remains controversial. Ablation and chemoembolization are considered for nonoperative candidates. This study compares survival among patients with solitary HCC ≤ 3 cm treated with radiofrequ ...
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Journal articleJ Glob Oncol · January 2019
PURPOSE: The WHO framework for early cancer diagnosis highlights the need to improve health care capacity among primary care providers. In Rwanda, general practitioners (GPs) at district hospitals (DHs) play key roles in diagnosing, initiating management, ...
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Journal articleEast and Central African Journal of Surgery · December 31, 2018
Background: Teaching surgical skills in the simulation lab has increased markedly compared to teaching only in the operating room. Although many studies have been performed investigating the optimal teaching methodology for skills acquisition, ther ...
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Journal articleJ Surg Oncol · December 2018
BACKGROUND: Gastric cancer is the fifth most common cancer in Eastern Africa. Diagnostic delays in low-resource countries result in advanced disease presentation. We describe perioperative management of gastric cancer in Rwanda. METHODS: A retrospective re ...
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ConferenceBlood · November 29, 2018
AbstractIntroduction: Daratumumab is an anti-CD38 monoclonal antibody, currently FDA approved for treatment of newly diagnosed transplant ineligible multiple myeloma (MM) in combination with melphalan, predn ...
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Journal articleJ Surg Res · November 2018
BACKGROUND: Safety of pancreaticoduodenectomy has improved significantly in the past 3 decades. Current inpatient and 30-d mortality rates are low. However, incidence and causes of 90-d and 1-y mortality are poorly defined and largely unexplored. METHODS: ...
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Journal articleAm J Surg · September 2018
BACKGROUND: This study aims to test associations between perioperative blood transfusion and postoperative morbidity and mortality after major abdominal operations. METHODS: The 2014 ACS NSQIP dataset was queried for all patients who underwent one of the t ...
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Journal articleSurg Endosc · May 2018
BACKGROUND: Minimally invasive surgery (MIS) for rectal cancer has increased in recent years. Enhanced recovery (ER) protocols are associated with improved outcomes, such as decreased length of stay (LOS). We examined the impact of MIS and ER protocols on ...
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Journal articleJ Gastrointest Surg · April 2018
BACKGROUND: Despite technical advances, bile leak remains a significant complication after hepatectomy. The current study uses a targeted multi-institutional dataset to characterize perioperative factors that are associated with bile leakage after hepatect ...
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Journal articleNeuro Oncol · March 27, 2018
BACKGROUND: Despite recommendations from professional organizations supporting early hospice enrollment for patients with cancer, little research exists regarding end-of-life (EOL) practices for patients with malignant glioma (MG). We evaluated rates and c ...
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Journal articlePLoS One · 2018
BACKGROUND: Pancreatic fistula remains a morbid complication after pancreatectomy. Since the proposed mechanism of pancreatic fistula is different between pancreaticoduodenectomy and distal pancreatectomy, we hypothesized that pancreatic gland texture and ...
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Journal articleJ Pediatr Urol · December 2017
INTRODUCTION: Over the last decade the literature, including a multidisciplinary consensus statement, has supported a paradigm shift in management of urinary tract dilation, yet the impact on practice patterns has not been well documented. OBJECTIVE: This ...
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Journal articleGynecol Oncol Rep · August 2017
In limited resource settings such as Rwanda, visual inspection with acetic acid (VIA) is the primary model for cervical cancer screening. The objective of this study was to describe clinical characteristics and outcomes for women presenting for cervical ca ...
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Journal articleSurg Obes Relat Dis · June 2017
BACKGROUND: Bariatric centers frequently provide preoperative educational programs to inform patients about the risks and benefits of weight loss surgery. However, most programs are conducted in English, which may create barriers to effective treatment and ...
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ConferenceJournal of Clinical Oncology · May 20, 2017
e16031 Background: Atezo was recently FDA-approved for patients (pts) with UC (IMvigor210 trial). We assessed the safety and efficacy of Atezo in the real world setting and explored the role of putative biomarkers. Methods: Data ...
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Journal articleAm J Surg · March 2017
BACKGROUND: Total abdominal colectomy (TAC) is the standard surgical treatment of Clostridium difficile infection (CDI). An alternative therapy, loop ileostomy and colonic lavage (IL), was described in 2011, but the results have never been validated. METHO ...
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Journal articleJ Surg Res · November 2016
BACKGROUND: Previous studies have indicated that blood transfusion is associated with increased risk of worse outcomes among patients selected for hepatectomy. However, the independent effect of transfusion has not been confirmed. We hypothesize that blood ...
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Journal articleClin Transplant · November 2016
OBJECTIVE: The purpose of this study was to determine whether bacterial contamination of islets affects graft success after total pancreatectomy with islet autotransplantation (TPIAT). BACKGROUND: Factors associated with insulin independence after TPIAT ar ...
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Journal articleAm J Surg · October 2016
BACKGROUND: The purpose of this study was to identify factors that predict medical student success in acquiring invasive procedural skills. We hypothesized that students with interest in surgery and with prior procedural experience would have higher rates ...
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Journal articleSurgery · September 2016
BACKGROUND: Four-dimensional computed tomography is being used increasingly for localization of abnormal glands in primary hyperparathyroidism. We hypothesized that compared with traditional 4-phase imaging, 2-phase imaging would halve the radiation dose w ...
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Journal articleJ Gastrointest Surg · September 2016
BACKGROUND: Morbidity after gastrectomy remains high. The potentially modifiable risk factors have not been well described. This study considers a series of potentially modifiable patient-specific and perioperative characteristics that could be considered ...
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Journal articleCancer Immunol Immunother · March 2016
Natural killer (NK) cells are the primary effectors of the innate immune response against virus-infected cells or cells that have undergone malignant transformation. NK cells recognize their targets through a complex array of activating and inhibitory rece ...
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ConferenceJournal of Clinical Oncology · March 1, 2015
210 Background: Ra-223 is an α-emitter that binds to the newly formed bone matrix and targets osteoblastic metastatic lesions. Treatment with Ra-223 delays symptomatic skeletal-related events (SREs) and improves overall survival ...
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ConferenceBlood · November 15, 2013
AbstractNK cells are the primary effectors of the innate immune response against infections pathogens and malignant transformation through their efficient cytolytic activity and cytokine secretion. Neverthel ...
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ConferenceBlood · November 16, 2012
AbstractAbstract 2152NK cells are the primary effectors of the innate immune response against cells that have undergone malignant transformation. Unlike T cells, NK cells rec ...
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Journal articleCell Res · March 2007
RNase MRP RNA is the RNA subunit of the RNase mitochondrial RNA processing (MRP) enzyme complex that is involved in multiple cellular RNA processing events. Mutations on RNase MRP RNA gene (RMRP) cause a recessively inherited developmental disorder, cartil ...
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