Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., Northwestern University 1968
  • B.A., Knox College 1964
• 

  Duke Appointment History

  • Professor with Tenure, Chemistry, Trinity College of Arts & Sciences 1986 - 2016
  • Dean of the Faculty of Arts and Sciences and Dean of Trinity College, Trinity College of Arts & Sciences, Duke University 2010 - 2011
  • Dean of the Natural Sciences, Trinity College of Arts & Sciences, Duke University 2007 - 2010
  • Chair, Chemistry, Trinity College of Arts & Sciences 1991 - 1994
  • Associate Professor with Tenure, Chemistry, Trinity College of Arts & Sciences 1976 - 1986
  • Assistant Professor, Chemistry, Trinity College of Arts & Sciences 1970 - 1976
• Recognition
• 

  In the News

  • MAY 5, 2016

    Nautilus

    Al Crumbliss: The classic metal behind the origins of life
• 

  Awards & Honors

  • AAAS Fellows. American Association for the Advancement of Science, The. 2012
  • ACS Fellows. American Chemical Society. 2011
  • Bass Fellow and Bishop-MacDermott Family Professor of Chemistry. Bass Society of Fellows. September 2008
  • Dean's Distinguished Service Award. Duke University. September 2008
• Research
• 

  Selected Grants

  • GAANN - Department of Chemistry awarded by Department of Education 2015 - 2019
  • BioMetals 2014 Conference at Duke University awarded by National Institutes of Health 2014 - 2015
  • Gertrude Elion NC-ACS Undergraduate Scholarship Award awarded by American Chemical Society 2014 - 2015
  • BioMetals 2014 Conference at Duke University awarded by North Carolina Biotechnology Center 2014
  • Kinetic and Thermodynamic Studies Relevant to Biological Iron Transport awarded by  National Science Foundation 2005 - 2012
  • Training in Biomolecular and Tissue Engineering awarded by National Institutes of Health 2003 - 2009
  • Graduate training in Biologically Inspired Materials awarded by  National Science Foundation 2002 - 2007
  • Mechanisms of Iron-Ligand Exchange Reactions and the Influence of Ionophore Hosts in the Second-Sphere awarded by  National Science Foundation 1999 - 2005
  • Interaction of Actinide Species with Microorganisms and Microbial Chelators: Cellular Uptake, Toxicity, and Implicating Implications for Bioremediation of Soil and Ground Water awarded by Department of Energy 2001 - 2004
  • NATO Postdoctoral Research Fellowship: M. Gabricevic awarded by  National Science Foundation 2002 - 2004
  • Acquisition of a Time-Resolved Step-Scan Fourier Transform Infrared Spectrometer awarded by  National Science Foundation 2001 - 2004
  • Molecular Controls of Hemoglobin Function awarded by National Institutes of Health 1996 - 2002
  • Marine/Freshwater Biomedical Center awarded by National Institute of Environmental Health Science 1999 - 2002
  • Novel NMR Reporter Probes for Dynamic Metalloprotein Studies awarded by National Institutes of Health 1999 - 2001
  • Molecular Controls of Hemoglobin Function awarded by National Institutes of Health 1996 - 2001
  • Molecular Controls of Hemoglobin Function awarded by National Institutes of Health 1996 - 2001
  • Mechanisms of Iron-Ligand Exchange Reactions and the Influence of Ionophore Hosts and Micelles in the Second-Sphere awarded by  National Science Foundation 1997 - 2000
  • Mechanisms of Iron-ligand Exchange Reactions and the Influence of Ionophore Hosts awarded by  National Science Foundation 1997 - 2000
  • Chelator Combinatorial Libraries for Iron Overload Drugs awarded by National Institutes of Health 1992 - 2000
  • Kinetics and Mechanism of Iron-Ligand Exchange Reactions in the Presence of Surfactants and/or Crown Ethers awarded by  National Science Foundation 1991 - 1994
  • Kinetics and Mechanisms of Iron-Ligant Exchange Reactions in the Presence of Surfactants and/or Grown Ethers awarded by  National Science Foundation 1991 - 1993
  • Individual Exchange Program with Yugoslavia awarded by National Research Council 1992 - 1993
  • Kinetics and Mechanisms of Iron-Ligand Exchange Reactions in the Presence of Surfactants and/or Crown Ethers awarded by  National Science Foundation 1991 - 1993
  • Oxygen Permselective Metal Macrocycle Containing Plasma Polymer Membranes awarded by Army Research Office 1988 - 1991
  • Oxygen Permselective Metal-Macrocucle Containing Plasma Polymer Membranes awarded by Army Research Office 1988 - 1991
  • Oxygen Permaselective Metal-Macrocycle Containing Plasma Polymer Membranes awarded by Army Research Office 1988 - 1990
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Harrington, James M., Manu M. Mysore, and Alvin L. Crumbliss. “The kinetics of dimethylhydroxypyridinone interactions with iron(iii) and the catalysis of iron(iii) ligand exchange reactions: implications for bacterial iron transport and combination chelation therapies.” Dalton Transactions (Cambridge, England : 2003) 47, no. 20 (May 2018): 6954–64. https://doi.org/10.1039/c8dt01329b.
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    • Ciferri, Alberto, and Alvin L. Crumbliss. “The Assembling and Contraction Mechanisms of Striated Muscles.” Frontiers in Chemistry 6 (January 2018): 570. https://doi.org/10.3389/fchem.2018.00570.
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    • Strader, Michael Brad, Rachel Bangle, Claire J. Parker Siburt, Cornelius L. Varnado, Jayashree Soman, Andres S. Benitez Cardenas, Premila P. Samuel, et al. “Engineering oxidative stability in human hemoglobin based on the Hb providence (βK82D) mutation and genetic cross-linking.” The Biochemical Journal 474, no. 24 (December 11, 2017): 4171–92. https://doi.org/10.1042/bcj20170491.
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    • Gupta, Ajay, Raymond D. Pratt, and Alvin L. Crumbliss. “Ferrous iron content of intravenous iron formulations.” Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 29, no. 3 (June 2016): 411–15. https://doi.org/10.1007/s10534-016-9923-7.
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    • Crumbliss, Alvin L., Katherine J. Franz, and Dennis J. Thiele. “Preface. Biometals 2014--Proceedings of the 9th International Symposium Biometals 2014 at Duke University, Durham, NC, USA.” Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 28, no. 3 (June 2015): 431. https://doi.org/10.1007/s10534-015-9854-8.
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    • Banerjee, Sambuddha, Aruna J. Weerasinghe, Claire J. Parker Siburt, R Timothy Kreulen, Sandra K. Armstrong, Timothy J. Brickman, Lisa A. Lambert, and Alvin L. Crumbliss. “Bordetella pertussis FbpA binds both unchelated iron and iron siderophore complexes.” Biochemistry 53, no. 24 (June 13, 2014): 3952–60. https://doi.org/10.1021/bi5002823.
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    • Mollan, Todd L., Yiping Jia, Sambuddha Banerjee, Gang Wu, R Timothy Kreulen, Ah-Lim Tsai, John S. Olson, Alvin L. Crumbliss, and Abdu I. Alayash. “Redox properties of human hemoglobin in complex with fractionated dimeric and polymeric human haptoglobin.” Free Radical Biology & Medicine 69 (April 2014): 265–77. https://doi.org/10.1016/j.freeradbiomed.2014.01.030.
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    • Miller, Eric P., Lars H. Böttger, Aruna J. Weerasinghe, Alvin L. Crumbliss, Berthold F. Matzanke, Wolfram Meyer-Klaucke, Frithjof C. Küpper, and Carl J. Carrano. “Surface-bound iron: a metal ion buffer in the marine brown alga Ectocarpus siliculosus?” Journal of Experimental Botany 65, no. 2 (February 2014): 585–94. https://doi.org/10.1093/jxb/ert406.
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    • Weerasinghe, Aruna J., Shady A. Amin, Ryan A. Barker, Thaer Othman, Ariel N. Romano, Claire J. Parker Siburt, Jerrell Tisnado, et al. “Borate as a synergistic anion for Marinobacter algicola ferric binding protein, FbpA: a role for boron in iron transport in marine life.” Journal of the American Chemical Society 135, no. 39 (October 2013): 14504–7. https://doi.org/10.1021/ja406609s.
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    • Fago, Angela, Alvin L. Crumbliss, Michael P. Hendrich, Linda L. Pearce, Jim Peterson, Robert Henkens, and Celia Bonaventura. “Oxygen binding to partially nitrosylated hemoglobin.” Biochimica Et Biophysica Acta 1834, no. 9 (September 2013): 1894–1900. https://doi.org/10.1016/j.bbapap.2013.04.017.
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    • Grant, Gerald A., Todd Hankinson, Carrie Muh, and Aaron Dumont. “The 62nd Annual Meeting of the Congress of Neurological Surgeons was held in Chicago, Illinois from October 6-10, 2012. Preface.” Neurosurgery 60 Suppl 1 (August 2013): v. https://doi.org/10.1227/NEU.0000000000000006.
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    • Romano, Ariel, Lyndsay Trimble, Ashtian R. Hobusch, Kristine J. Schroeder, Shady A. Amin, Andrej D. Hartnett, Ryan A. Barker, Alvin L. Crumbliss, and Carl J. Carrano. “Regulation of iron transport related genes by boron in the marine bacterium Marinobacter algicola DG893.” Metallomics : Integrated Biometal Science 5, no. 8 (August 2013): 1025–30. https://doi.org/10.1039/c3mt00068k.
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    • Bonaventura, Celia, Robert Henkens, Abdu I. Alayash, Sambuddha Banerjee, and Alvin L. Crumbliss. “Molecular controls of the oxygenation and redox reactions of hemoglobin.” Antioxidants & Redox Signaling 18, no. 17 (June 2013): 2298–2313. https://doi.org/10.1089/ars.2012.4947.
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    • Mollan, Todd L., Sambuddha Banerjee, Gang Wu, Claire J. Parker Siburt, Ah-Lim Tsai, John S. Olson, Mitchell J. Weiss, Alvin L. Crumbliss, and Abdu I. Alayash. “α-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of α-subunits of human HbA with hydrogen peroxide.” The Journal of Biological Chemistry 288, no. 6 (February 2013): 4288–98. https://doi.org/10.1074/jbc.m112.412064.
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    • Harrington, James M., Tom Gootz, Mark Flanagan, Majinder Lall, John O’Donnell, Jennifer Winton, John Mueller, and Alvin L. Crumbliss. “Characterization of the aqueous iron(III) chelation chemistry of a potential Trojan Horse antimicrobial agent: chelate structure, stability and pH dependent speciation.” Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 25, no. 5 (October 2012): 1023–36. https://doi.org/10.1007/s10534-012-9568-0.
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    • Banerjee, Sambuddha, Yiping Jia, Claire J Parker Siburt, Bindu Abraham, Francine Wood, Celia Bonaventura, Robert Henkens, Alvin L. Crumbliss, and Abdu I. Alayash. “Haptoglobin alters oxygenation and oxidation of hemoglobin and decreases propagation of peroxide-induced oxidative reactions.” Free Radical Biology & Medicine 53, no. 6 (September 2012): 1317–26. https://doi.org/10.1016/j.freeradbiomed.2012.07.023.
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    • Harrington, James M., Windy A. Boyd, Marjolein V. Smith, Julie R. Rice, Jonathan H. Freedman, and Alvin L. Crumbliss. “Amelioration of metal-induced toxicity in Caenorhabditis elegans: utility of chelating agents in the bioremediation of metals.” Toxicological Sciences : An Official Journal of the Society of Toxicology 129, no. 1 (September 2012): 49–56. https://doi.org/10.1093/toxsci/kfs191.
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    • Kraiter, D. C., P. Wisian-Neilson, C. Zhang, and A. L. Crumbliss. “Synthesis and redox characterization of phosphazene terpolymers with pendant ferrocene groups.” Macromolecules 45, no. 9 (May 8, 2012): 3658–68. https://doi.org/10.1021/ma300336e.
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    • Banerjee, Sambuddha, Claire J Parker Siburt, Shreni Mistry, Jennifer M. Noto, Patrick DeArmond, Michael C. Fitzgerald, Lisa A. Lambert, Cynthia N. Cornelissen, and Alvin L. Crumbliss. “Evidence of Fe3+ interaction with the plug domain of the outer membrane transferrin receptor protein of Neisseria gonorrhoeae: implications for Fe transport.” Metallomics : Integrated Biometal Science 4, no. 4 (April 2012): 361–72. https://doi.org/10.1039/c2mt20037f.
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    • Parker Siburt, Claire J., Timothy A. Mietzner, and Alvin L. Crumbliss. “FbpA--a bacterial transferrin with more to offer.” Biochimica Et Biophysica Acta 1820, no. 3 (March 2012): 379–92. https://doi.org/10.1016/j.bbagen.2011.09.001.
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    • Tran, Duc T., Sambuddha Banerjee, Abdu I. Alayash, Alvin L. Crumbliss, and Michael C. Fitzgerald. “Slow histidine H/D exchange protocol for thermodynamic analysis of protein folding and stability using mass spectrometry.” Analytical Chemistry 84, no. 3 (February 2012): 1653–60. https://doi.org/10.1021/ac202927p.
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    • Crumbliss, A. L., and C. J. Parker Siburt. “Iron Transport in Living Cells,” January 13, 2012, 483–549. https://doi.org/10.1002/9781118165850.ch13.
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    • Harrington, James M., Günther Winkelmann, Kurt Haselwandter, and Alvin L. Crumbliss. “Fe(III)-complexes of the tripodal trishydroxamate siderophore basidiochrome: potential biological implications.” Journal of Inorganic Biochemistry 105, no. 12 (December 2011): 1670–74. https://doi.org/10.1016/j.jinorgbio.2011.08.010.
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    • Bonaventura, Celia, Robert Henkens, Joel Friedman, Claire J Parker Siburt, Daniel Kraiter, and Alvin L. Crumbliss. “Steric factors moderate conformational fluidity and contribute to the high proton sensitivity of Root effect hemoglobins.” Biochimica Et Biophysica Acta 1814, no. 10 (October 2011): 1261–68. https://doi.org/10.1016/j.bbapap.2011.06.012.
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    • Harrington, James M., Heekwang Park, Yongcheng Ying, Jiyong Hong, and Alvin L. Crumbliss. “Characterization of Fe(III) sequestration by an analog of the cytotoxic siderophore brasilibactin A: implications for the iron transport mechanism in mycobacteria.” Metallomics : Integrated Biometal Science 3, no. 5 (May 2011): 464–71. https://doi.org/10.1039/c0mt00109k.
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    • Miller, Marvin J., Andrew J. Walz, Helen Zhu, Chunrui Wu, Garrett Moraski, Ute Möllmann, Esther M. Tristani, et al. “Design, synthesis, and study of a mycobactin-artemisinin conjugate that has selective and potent activity against tuberculosis and malaria.” Journal of the American Chemical Society 133, no. 7 (February 2011): 2076–79. https://doi.org/10.1021/ja109665t.
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    • Tristani, E. M., J. I. Wirgau, G. R. Dubay, J. W. Sibert, and A. L. Crumbliss. “Siderophore-redox active ionophore host-guest assemblies: A prototype for selective metal ion compartmentalization.” Inorganica Chimica Acta 363, no. 13 (October 25, 2010): 3611–15. https://doi.org/10.1016/j.ica.2010.05.052.
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    • Bonaventura, Celia, Robert Henkens, Walleska De Jesus-Bonilla, Juan Lopez-Garriga, Yiping Jia, Abdu I. Alayash, Claire J Parker Siburt, and Alvin L. Crumbliss. “Extreme differences between hemoglobins I and II of the clam Lucina pectinalis in their reactions with nitrite.” Biochimica Et Biophysica Acta 1804, no. 10 (October 2010): 1988–95. https://doi.org/10.1016/j.bbapap.2010.06.016.
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    • Harrington, James M., Sumathi Chittamuru, Suraj Dhungana, Hollie K. Jacobs, Aravamudan S. Gopalan, and Alvin L. Crumbliss. “Synthesis and iron sequestration equilibria of novel exocyclic 3-hydroxy-2-pyridinone donor group siderophore mimics.” Inorganic Chemistry 49, no. 18 (September 2010): 8208–21. https://doi.org/10.1021/ic902595c.
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    • Parker Siburt, Claire J., Emily M. Lin, Sara J. Brandt, Arthur D. Tinoco, Ann M. Valentine, and Alvin L. Crumbliss. “Redox potentials of Ti(IV) and Fe(III) complexes provide insights into titanium biodistribution mechanisms.” Journal of Inorganic Biochemistry 104, no. 9 (September 2010): 1006–9. https://doi.org/10.1016/j.jinorgbio.2010.04.004.
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    • Weaver, Katherine D., Mario Gabricević, Damon S. Anderson, Pratima Adhikari, Timothy A. Mietzner, and Alvin L. Crumbliss. “Role of citrate and phosphate anions in the mechanism of iron(III) sequestration by ferric binding protein: kinetic studies of the formation of the holoprotein of wild-type FbpA and its engineered mutants.” Biochemistry 49, no. 29 (July 2010): 6021–32. https://doi.org/10.1021/bi902231c.
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    • Heymann, Jared J., Mario Gabricević, Timothy A. Mietzner, and Alvin L. Crumbliss. “Kinetics and mechanism of exogenous anion exchange in FeFbpA-NTA: significance of periplasmic anion lability and anion binding activity of ferric binding protein A.” Journal of Biological Inorganic Chemistry : Jbic : A Publication of the Society of Biological Inorganic Chemistry 15, no. 2 (February 2010): 237–48. https://doi.org/10.1007/s00775-009-0589-2.
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    • Harrington, James M., and Alvin L. Crumbliss. “The redox hypothesis in siderophore-mediated iron uptake.” Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 22, no. 4 (August 2009): 679–89. https://doi.org/10.1007/s10534-009-9233-4.
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    • Crumbliss, A. L., and J. M. Harrington. “Iron sequestration by small molecules: Thermodynamic and kinetic studies of natural siderophores and synthetic model compounds.” Advances in Inorganic Chemistry 61 (July 8, 2009): 179–250. https://doi.org/10.1016/S0898-8838(09)00204-9.
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    • Tristani, E. M., G. R. Dubay, and A. L. Crumbliss. “Characterization of second coordination shell ionophore-siderophore host-guest assemblies and binding selectivities in binary and complex mixtures by electrospray ionization mass spectrometry.” Journal of Inclusion Phenomena and Macrocyclic Chemistry 64, no. 1–2 (June 1, 2009): 57–65. https://doi.org/10.1007/s10847-009-9536-7.
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    • Siburt, Claire J Parker, Petra L. Roulhac, Katherine D. Weaver, Jennifer M. Noto, Timothy A. Mietzner, Cynthia N. Cornelissen, Michael C. Fitzgerald, and Alvin L. Crumbliss. “Hijacking transferrin bound iron: protein-receptor interactions involved in iron transport in N. gonorrhoeae.” Metallomics : Integrated Biometal Science 1, no. 3 (January 2009): 249–55. https://doi.org/10.1039/b902860a.
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    • Weaver, Katherine D., Jared J. Heymann, Arnav Mehta, Petra L. Roulhac, Damon S. Anderson, Andrew J. Nowalk, Pratima Adhikari, Timothy A. Mietzner, Michael C. Fitzgerald, and Alvin L. Crumbliss. “Ga3+ as a mechanistic probe in Fe3+ transport: characterization of Ga3+ interaction with FbpA.” Journal of Biological Inorganic Chemistry : Jbic : A Publication of the Society of Biological Inorganic Chemistry 13, no. 6 (August 2008): 887–98. https://doi.org/10.1007/s00775-008-0376-5.
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    • Flaherty, Meghan M., Kimberley R. Rish, Ann Smith, and Alvin L. Crumbliss. “An investigation of hemopexin redox properties by spectroelectrochemistry: biological relevance for heme uptake.” Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 21, no. 3 (June 2008): 239–48. https://doi.org/10.1007/s10534-007-9112-9.
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    • Mies, Kassy A., Peter Gebhardt, Ute Möllmann, and Alvin L. Crumbliss. “Synthesis, siderophore activity and iron(III) chelation chemistry of a novel mono-hydroxamate, bis-catecholate siderophore mimic: N(alpha),-N(epsilon)-Bis[2,3-dihydroxybenzoyl]-l-lysyl-(gamma-N-methyl-N-hydroxyamido)-L-glutamic acid.” Journal of Inorganic Biochemistry 102, no. 4 (April 2008): 850–61. https://doi.org/10.1016/j.jinorgbio.2007.11.021.
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    • Roulhac, Petra L., Katherine D. Weaver, Pratima Adhikari, Damon S. Anderson, Patrick D. DeArmond, Timothy A. Mietzner, Alvin L. Crumbliss, and Michael C. Fitzgerald. “Ex vivo analysis of synergistic anion binding to FbpA in Gram-negative bacteria.” Biochemistry 47, no. 14 (April 2008): 4298–4305. https://doi.org/10.1021/bi701188x.
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    • Gebhardt, Peter, Alvin L. Crumbliss, Marvin J. Miller, and Ute Möllmann. “Synthesis and biological activity of saccharide based lipophilic siderophore mimetics as potential growth promoters for mycobacteria.” Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 21, no. 1 (February 2008): 41–51. https://doi.org/10.1007/s10534-007-9091-x.
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    • Heymann, J. J., M. Gabričević, T. A. Mietzner, and A. L. Crumbliss. “Kinetics and Mechanism of Exogenous Anion Exchange in FeFbpA-NTA: Periplasmic Anion Lability and a Model for Acquisition Through Non-transferrin Bound Iron Sources (Submitted).” Biochemistry, 2008.
    • Tristani, E. M., D. B. Chesnut, and A. L. Crumbliss. “General Chemistry and the NO2 / N2O4 System: It’s Not as Simple as it Appears (and That Can Make it an Enrichment Tool) (Submitted).” J. Chem. Ed., 2008.
    • Dhungana, Suraj, James M. Harrington, Peter Gebhardt, Ute Möllmann, and Alvin L. Crumbliss. “Iron chelation equilibria, redox, and siderophore activity of a saccharide platform ferrichrome analogue.” Inorganic Chemistry 46, no. 20 (October 2007): 8362–71. https://doi.org/10.1021/ic070158l.
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    • Remington, Nicole, Robert D. Stevens, Randall S. Wells, Aleta Holn, Suraj Dhungana, Celine H. Taboy, Alvin L. Crumbliss, Robert Henkens, and Celia Bonaventura. “Genetic diversity of coastal bottlenose dolphins revealed by structurally and functionally diverse hemoglobins.” Gene 398, no. 1–2 (August 15, 2007): 123–31. https://doi.org/10.1016/j.gene.2007.02.050.
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    • Bonaventura, Celia, Robert Henkens, Abdu I. Alayash, and Alvin L. Crumbliss. “Allosteric effects on oxidative and nitrosative reactions of cell-free hemoglobins.” Iubmb Life 59, no. 8–9 (August 2007): 498–505. https://doi.org/10.1080/15216540601188546.
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    • Heymann, J. J., K. D. Weaver, T. A. Mietzner, and A. L. Crumbliss. “Sulfate as a synergistic anion facilitating iron binding by the bacterial transferrin FbpA: the origins and effects of anion promiscuity.” Journal of the American Chemical Society 129, no. 31 (August 2007): 9704–12. https://doi.org/10.1021/ja0709268.
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    • Anderson, Damon S., Pratima Adhikari, Katherine D. Weaver, Alvin L. Crumbliss, and Timothy A. Mietzner. “The Haemophilus influenzae hFbpABC Fe3+ transporter: analysis of the membrane permease and development of a gallium-based screen for mutants.” Journal of Bacteriology 189, no. 14 (July 2007): 5130–41. https://doi.org/10.1128/jb.00145-07.
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    • Anderson, D. S., P. Adhikari, K. D. Weaver, A. L. Crumbliss, and T. A. Mietzner. “The Haemophilus influenzae hFbpABC Fe3+ Transporter: Analysis of the Membrane Permease and Development of a Mutational Screen Based on Resistance to Gallium.” J. Bacteriology 189 (2007).
    • Dhungana, S., J. M. Harrington, P. Gebhardt, U. Möllmann, and A. L. Crumbliss. “Iron Coordination Properties of a Saccharide Platform Ferrichrome Analogue.” Inorg. Chem. 46 (2007).
    • Valdebenito, Marianne, Alvin L. Crumbliss, Günther Winkelmann, and Klaus Hantke. “Environmental factors influence the production of enterobactin, salmochelin, aerobactin, and yersiniabactin in Escherichia coli strain Nissle 1917.” International Journal of Medical Microbiology : Ijmm 296, no. 8 (December 2006): 513–20. https://doi.org/10.1016/j.ijmm.2006.06.003.
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    • Mies, Kassy A., Joseph I. Wirgau, and Alvin L. Crumbliss. “Ternary complex formation facilitates a redox mechanism for iron release from a siderophore.” Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 19, no. 2 (April 2006): 115–26. https://doi.org/10.1007/s10534-005-4342-1.
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    • Chesnut, D. B., and A. L. Crumbliss. “An ELF and AIM study of NO2 and N2O4.” Chemical Physics 315, no. 1–2 (August 8, 2005): 53–58. https://doi.org/10.1016/j.chemphys.2005.04.002.
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    • Dhungana, Suraj, Damon S. Anderson, Timothy A. Mietzner, and Alvin L. Crumbliss. “Kinetics of iron release from ferric binding protein (FbpA): mechanistic implications in bacterial periplasm-to-cytosol Fe3+ transport.” Biochemistry 44, no. 28 (July 2005): 9606–18. https://doi.org/10.1021/bi0505518.
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    • Summers, Jack S., Karel Base, Hakim Boukhalfa, Jason E. Payne, Barbara Ramsay Shaw, and Alvin L. Crumbliss. “Use of phosphorus ligand NMR probes to investigate electronic and second-sphere solvent effects in ligand substitution reactions at manganese(II) and manganese(III).” Inorganic Chemistry 44, no. 10 (May 2005): 3405–11. https://doi.org/10.1021/ic048618n.
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    • Dhungana, S., and A. L. Crumbliss. “Coordination chemistry and redox processes in siderophore-mediated iron transport.” Geomicrobiology Journal 22, no. 3–4 (April 1, 2005): 87–98. https://doi.org/10.1080/01490450590945870.
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    • Bonaventura, Celia, Angela Fago, Robert Henkens, and Alvin L. Crumbliss. “Critical redox and allosteric aspects of nitric oxide interactions with hemoglobin.” Antioxidants & Redox Signaling 6, no. 6 (December 2004): 979–91. https://doi.org/10.1089/ars.2004.6.979.
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    • Roulhac, Petra L., Kendall D. Powell, Suraj Dhungana, Katherine D. Weaver, Timothy A. Mietzner, Alvin L. Crumbliss, and Michael C. Fitzgerald. “SUPREX (Stability of Unpurified Proteins from Rates of H/D Exchange) analysis of the thermodynamics of synergistic anion binding by ferric-binding protein (FbpA), a bacterial transferrin.” Biochemistry 43, no. 50 (December 2004): 15767–74. https://doi.org/10.1021/bi0481848.
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    • Bonaventura, C., A. L. Crumbliss, and R. E. Weber. “New insights into the proton-dependent oxygen affinity of Root effect haemoglobins.” Acta Physiologica Scandinavica 182, no. 3 (November 2004): 245–58. https://doi.org/10.1111/j.1365-201x.2004.01359.x.
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    • Dhungana, Suraj, Damon S. Anderson, Timothy A. Mietzner, and Alvin L. Crumbliss. “Phosphate ester hydrolysis is catalyzed by a bacterial transferrin: potential implications for in vivo iron transport mechanisms.” Journal of Inorganic Biochemistry 98, no. 11 (November 2004): 1975–77. https://doi.org/10.1016/j.jinorgbio.2004.08.004.
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    • Dhungana, Suraj, Colin Ratledge, and Alvin L. Crumbliss. “Iron chelation properties of an extracellular siderophore exochelin MS.” Inorganic Chemistry 43, no. 20 (October 2004): 6274–83. https://doi.org/10.1021/ic049343e.
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    • Heymann, J. J., and A. L. Crumbliss. “Kinetics and mechanism of axial ligand substitution of alkyl cobaloximes by substituted pyridines in different solvents.” Chemtracts 17, no. 10 (October 1, 2004): 527–33.
    • Gabricević, Mario, Damon S. Anderson, Timothy A. Mietzner, and Alvin L. Crumbliss. “Kinetics and mechanism of iron(III) complexation by ferric binding protein: the role of phosphate.” Biochemistry 43, no. 19 (May 2004): 5811–19. https://doi.org/10.1021/bi036217y.
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    • Boukhalfa, Hakim, James G. Lewis, and Alvin L. Crumbliss. “Beryllium(II) binding to ATP and ADP: potentiometric determination of the thermodynamic constants and implications for in vivo toxicity.” Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 17, no. 2 (April 2004): 105–9. https://doi.org/10.1023/b:biom.0000018359.25658.9c.
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    • Dhungana, Suraj, Céline H. Taboy, Olga Zak, Mykol Larvie, Alvin L. Crumbliss, and Philip Aisen. “Redox properties of human transferrin bound to its receptor.” Biochemistry 43, no. 1 (January 2004): 205–9. https://doi.org/10.1021/bi0353631.
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    • Dhungana, Suraj, Peter S. White, and Alvin L. Crumbliss. “Crystal and molecular structures of ionophore-siderophore host-guest supramolecular assemblies relevant to molecular recognition.” Journal of the American Chemical Society 125, no. 48 (December 2003): 14760–67. https://doi.org/10.1021/ja035778+.
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    • Boukhalfa, Hakim, Damon S. Anderson, Timothy A. Mietzner, and Alvin L. Crumbliss. “Kinetics and mechanism of iron release from the bacterial ferric binding protein nFbp: exogenous anion influence and comparison with mammalian transferrin.” Journal of Biological Inorganic Chemistry : Jbic : A Publication of the Society of Biological Inorganic Chemistry 8, no. 8 (November 2003): 881–92. https://doi.org/10.1007/s00775-003-0487-y.
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    • Weaver, K. D., and A. L. Crumbliss. “High-Resolution Structure of an Alternate Form of the Ferric Ion Binding Protein from Haemophilus influenzae.” Chemtracts 16, no. 12 (November 1, 2003): 715–21.
    • Fago, Angela, Alvin L. Crumbliss, Jim Peterson, Linda L. Pearce, and Celia Bonaventura. “The case of the missing NO-hemoglobin: spectral changes suggestive of heme redox reactions reflect changes in NO-heme geometry.” Proceedings of the National Academy of Sciences of the United States of America 100, no. 21 (October 2003): 12087–92. https://doi.org/10.1073/pnas.2032603100.
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    • Wirgau, J. I., and A. L. Crumbliss. “Carrier-facilitated bulk liquid membrane transport of iron(iii) hydroxamate complexes utilizing a labile recognition agent and amine recognition in the second coordination sphere.” Journal of the Chemical Society. Dalton Transactions 3, no. 19 (September 25, 2003): 3680–85. https://doi.org/10.1039/b306810b.
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    • Wirgau, Joseph I., and Alvin L. Crumbliss. “Carrier-facilitated bulk liquid membrane transport of iron(III)-siderophore complexes utilizing first coordination sphere recognition.” Inorganic Chemistry 42, no. 18 (September 2003): 5762–70. https://doi.org/10.1021/ic034157e.
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    • Kachadourian, Remy, Meghan M. Flaherty, Alvin L. Crumbliss, Manisha Patel, and Brian J. Day. “Synthesis and in vitro antioxidant properties of manganese(III) beta-octabromo-meso-tetrakis(4-carboxyphenyl)porphyrin.” Journal of Inorganic Biochemistry 95, no. 4 (July 2003): 240–48. https://doi.org/10.1016/s0162-0134(03)00135-1.
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    • Dhungana, Suraj, Marvin J. Miller, Li Dong, Colin Ratledge, and Alvin L. Crumbliss. “Iron chelation properties of an extracellular siderophore exochelin MN.” Journal of the American Chemical Society 125, no. 25 (June 2003): 7654–63. https://doi.org/10.1021/ja029578u.
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    • Gabricević, Mario, and Alvin L. Crumbliss. “Kinetics and mechanism of iron(III)-nitrilotriacetate complex reactions with phosphate and acetohydroxamic acid.” Inorganic Chemistry 42, no. 13 (June 2003): 4098–4101. https://doi.org/10.1021/ic026281o.
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    • Dhungana, Suraj, Celine H. Taboy, Damon S. Anderson, Kevin G. Vaughan, Philip Aisen, Timothy A. Mietzner, and Alvin L. Crumbliss. “The influence of the synergistic anion on iron chelation by ferric binding protein, a bacterial transferrin.” Proceedings of the National Academy of Sciences of the United States of America 100, no. 7 (April 2003): 3659–64. https://doi.org/10.1073/pnas.0536897100.
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    • Dhungana, Suraj, Susanne Heggemann, Peter Gebhardt, Ute Möllmann, and Alvin L. Crumbliss. “Fe(III) coordination properties of a new saccharide-based exocyclic trihydroxamate analogue of ferrichrome.” Inorganic Chemistry 42, no. 1 (January 2003): 42–50. https://doi.org/10.1021/ic025647u.
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    • Boukhalfa, Hakim, and Alvin L. Crumbliss. “Chemical aspects of siderophore mediated iron transport.” Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 15, no. 4 (December 2002): 325–39. https://doi.org/10.1023/a:1020218608266.
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    • Bonaventura, Celia, Celine H. Taboy, Philip S. Low, Robert D. Stevens, Celine Lafon, and Alvin L. Crumbliss. “Heme redox properties of S-nitrosated hemoglobin A0 and hemoglobin S: implications for interactions of nitric oxide with normal and sickle red blood cells.” J Biol Chem 277, no. 17 (April 26, 2002): 14557–63. https://doi.org/10.1074/jbc.M107658200.
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    • Wirgau, Joseph I., Ivan Spasojević, Hakim Boukhalfa, Ines Batinić-Haberle, and Alvin L. Crumbliss. “Thermodynamics, kinetics, and mechanism of the stepwise dissociation and formation of Tris(L-lysinehydroxamato)iron(III) in aqueous acid.” Inorg Chem 41, no. 6 (March 25, 2002): 1464–73. https://doi.org/10.1021/ic0109795.
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    • Taboy, Céline H., Celia Bonaventura, and Alvin L. Crumbliss. “Anaerobic oxidations of myoglobin and hemoglobin by spectroelectrochemistry.” Methods in Enzymology 353 (January 2002): 187–209. https://doi.org/10.1016/s0076-6879(02)53048-2.
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    • Dhungana, S., S. Heggemann, L. Heinisch, U. Möllmann, H. Boukhalfa, and A. L. Crumbliss. “Fe(III) coordination properties of two new saccharide-based enterobactin analogues: methyl 2,3,4-tris-O-[N-[2,3-di(hydroxy)benzoyl-glycyl]-aminopropyl]-alpha-D-glucopyranoside and methyl 2,3,4-tris-O-[N-[2,3-di-(hydroxy)-benzoyl]-aminopropyl]-alpha-D-glucopyranoside.” Inorganic Chemistry 40, no. 27 (December 2001): 7079–86. https://doi.org/10.1021/ic0104003.
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    • Summers, J. S., C. G. Hoogstraten, R. D. Britt, K. Base, B. R. Shaw, A. A. Ribeiro, and A. L. Crumbliss. “31P NMR probes of chemical dynamics: paramagnetic relaxation enhancement of the (1)H and (31)P NMR resonances of methyl phosphite and methylethyl phosphate anions by selected metal complexes.” Inorganic Chemistry 40, no. 26 (December 2001): 6547–54. https://doi.org/10.1021/ic010728w.
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    • Nguyen-Van-Duong, M. K., V. Guillot, L. Nicolas, A. Gaudemer, L. Lowry, I. Spasojević, and A. L. Crumbliss. “Synthesis, ligand pK(a), and Fe(III) complexation constants for a series of bipodal dihydroxamic acids.” Inorg Chem 40, no. 23 (November 5, 2001): 5948–53. https://doi.org/10.1021/ic0103143.
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    • Trzaska, S. M., M. Kim, R. A. Bartsch, and A. L. Crumbliss. “Optimization of the lariat ether carboxylic acid host structure for ferrioxamine B: demonstration of a second coordination shell chelate effect.” Inorganic Chemistry 40, no. 23 (November 2001): 5823–28. https://doi.org/10.1021/ic010095l.
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    • Dhungana, S., P. S. White, and A. L. Crumbliss. “Crystal structure of ferrioxamine B: a comparative analysis and implications for molecular recognition.” Journal of Biological Inorganic Chemistry : Jbic : A Publication of the Society of Biological Inorganic Chemistry 6, no. 8 (October 2001): 810–18. https://doi.org/10.1007/s007750100259.
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    • Olmstead, E. G., S. W. Harman, P. L. Choo, and A. L. Crumbliss. “Use of SDS micelles to stabilize a ternary intermediate in the reaction of ferrioxamine B and 1,10-phenanthroline.” Inorganic Chemistry 40, no. 21 (October 2001): 5420–27. https://doi.org/10.1021/ic0008621.
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    • Dhungana, S., and A. L. Crumbliss. “Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm.” Chemtracts 14, no. 5 (August 6, 2001): 258–65.
    • Flaherty, M., and A. L. Crumbliss. “Electron-induced inversion of helical chirality in copper complexes of N,N-dialkylmethionines.” Chemtracts 14, no. 5 (August 6, 2001): 237–42.
    • Boukhalfa, H., and A. L. Crumbliss. “Kinetics and mechanism of a catalytic chloride ion effect on the dissociation of model siderophore hydroxamate-iron(III) complexes.” Inorganic Chemistry 40, no. 17 (August 2001): 4183–90. https://doi.org/10.1021/ic010050k.
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    • Dhungana, S., and A. L. Crumbliss. “Can octahedral t2g⁶ complexes substitute associatively? The case of the isoelectronic Ruthenium(II) and Rhodium(III) hexaaquaions.” Chemtracts 14, no. 1 (January 1, 2001): 42–47.
    • Spasojević, I., H. Boukhalfa, R. D. Stevens, and A. L. Crumbliss. “Aqueous solution speciation of Fe(III) complexes with dihydroxamate siderophores alcaligin and rhodotorulic acid and synthetic analogues using electrospray ionization mass spectrometry.” Inorg Chem 40, no. 1 (January 1, 2001): 49–58. https://doi.org/10.1021/ic991390x.
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    • Summers, J. S., C. G. Hoogstraten, R. D. Britt, K. Base, B. R. Shaw, A. A. Riberio, and A. L. Crumbliss. “Enhancement of the 1H and 31P NMR Resonances of Methylphosphite and Methylethylphosphate Anions by Selected Metal Complexes.” Inorg. Chem. 40 (2001).
    • Taboy, C. H., K. G. Vaughan, T. A. Mietzner, P. Aisen, and A. L. Crumbliss. “Fe3+ coordination and redox properties of a bacterial transferrin.” The Journal of Biological Chemistry 276, no. 4 (January 2001): 2719–24. https://doi.org/10.1074/jbc.m004763200.
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    • Boukhalfa, H., T. J. Brickman, S. K. Armstrong, and A. L. Crumbliss. “Kinetics and mechanism of iron(III) dissociation from the dihydroxamate siderophores alcaligin and rhodotorulic acid.” Inorganic Chemistry 39, no. 25 (December 2000): 5591–5602. https://doi.org/10.1021/ic000330k.
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    • Dhungana, S., and A. L. Crumbliss. “Mutations at the histidine 249 ligand profoundly alter the spectral and iron-binding properties of human serum transferrin N-lobe: Mutation of the iron ligand His 249 to Glu in the N-lobe of human transferrin abolishes the dilysine "Trigger" but does not significantly affect iron release.” Chemtracts 13, no. 12 (December 1, 2000): 770–75.
    • Taboy, C. H., K. M. Faulkner, D. Kraiter, C. Bonaventura, and A. L. Crumbliss. “Concentration-dependent effects of anions on the anaerobic oxidation of hemoglobin and myoglobin.” The Journal of Biological Chemistry 275, no. 50 (December 2000): 39048–54. https://doi.org/10.1074/jbc.m004547200.
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    • Gupta, A., and A. L. Crumbliss. “Treatment of iron deficiency anemia: are monomeric iron compounds suitable for parenteral administration?” The Journal of Laboratory and Clinical Medicine 136, no. 5 (November 2000): 371–78. https://doi.org/10.1067/mlc.2000.110368.
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    • Boukhalfa, H., and A. L. Crumbliss. “Multiple-path dissociation mechanism for mono- and dinuclear tris(hydroxamato)iron(III) complexes with dihydroxamic acid ligands in aqueous solution.” Inorganic Chemistry 39, no. 19 (September 2000): 4318–31. https://doi.org/10.1021/ic0001659.
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    • Trzaska, S. M., E. J. Toone, and A. L. Crumbliss. “Microcalorimetric determination of thermodynamic parameters for ionophore-siderophore host-guest complex formation.” Inorganic Chemistry 39, no. 6 (March 2000): 1071–75. https://doi.org/10.1021/ic9908571.
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    • Spasojevic, Ivan, Sandra K. Armstrong, Timothy J. Brickman, and Alvin L. Crumbliss. “Electrochemical Behavior of the Fe(III) Complexes of the Cyclic Hydroxamate Siderophores Alcaligin and Desferrioxamine E.” Inorg Chem 38, no. 3 (February 8, 1999): 449–54. https://doi.org/10.1021/ic980635n.
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    • Bonaventura, C., G. Godette, S. Tesh, D. E. Holm, J. Bonaventura, A. L. Crumbliss, L. L. Pearce, and J. Peterson. “Internal electron transfer between hemes and Cu(II) bound at cysteine beta93 promotes methemoglobin reduction by carbon monoxide.” The Journal of Biological Chemistry 274, no. 9 (February 1999): 5499–5507. https://doi.org/10.1074/jbc.274.9.5499.
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    • Kowall, T., P. Caravan, H. Bourgeois, L. Helm, F. P. Rotzinger, and A. E. Merbach. “Interpretation of activation volumes for water exchange reactions revisited: Ab initio calculations for Al³⁺, Ga³⁺, and In³⁺, and new experimental data.” Chemtracts 12, no. 2 (February 1, 1999): 102–9.
    • Taboy, C. H., C. Bonaventura, and A. L. Crumbliss. “Spectroelectrochemistry of heme proteins: effects of active-site heterogeneity on Nernst plots.” Bioelectrochemistry and Bioenergetics (Lausanne, Switzerland) 48, no. 1 (February 1999): 79–86. https://doi.org/10.1016/s0302-4598(98)00236-0.
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    • Spasojević, I., and A. L. Crumbliss. “PH induced active ("Uphill") liquid membrane transport of ferrioxamine B by the ionizable ionophore lasalocid.” Inorganic Chemistry 38, no. 13 (January 1, 1999): 3248–50. https://doi.org/10.1021/ic9813664.
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    • Spasojević, I., and A. L. Crumbliss. “Bulk liquid membrane transport of ferrioxamine B by neutral and ionizable carriers.” Journal of the Chemical Society  Dalton Transactions, no. 23 (December 7, 1998): 4021–27. https://doi.org/10.1039/a804391d.
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    • Urano, Y., T. Higuchi, M. Hirobe, and T. Nagano. “Pronounced axial thiolate ligand effect on the reactivity of high-valent oxo-iron porphyrin intermediate.” Chemtracts 11, no. 5 (May 1, 1998): 327–32.
    • Albrecht-Gary, A. M., and A. L. Crumbliss. “Coordination chemistry of siderophores: thermodynamics and kinetics of iron chelation and release.” Metal Ions in Biological Systems 35 (January 1998): 239–327.
    • Batinić-Haberle, I., I. Spasojević, Y. Jang, R. A. Bartsch, and A. L. Crumbliss. “Lariat Ether Carboxylic Acids as Ionizable Hosts in the Second Coordination Sphere of the Siderophore Ferrioxamine B in Chloroform.” Inorganic Chemistry 37, no. 7 (January 1, 1998): 1438–45. https://doi.org/10.1021/ic970925o.
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    • Bonaventura, C., S. Tesh, K. M. Faulkner, D. Kraiter, and A. L. Crumbliss. “Conformational fluctuations in deoxy hemoglobin revealed as a major contributor to anionic modulation of function through studies of the oxygenation and oxidation of hemoglobins A0 and Deer Lodge beta2(NA2)His --> Arg.” Biochemistry 37, no. 2 (January 1998): 496–506. https://doi.org/10.1021/bi971574s.
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    • Caldwell, C. D., and A. L. Crumbliss. “Molecular Recognition of Ferrioxamine B by Host-Guest Complex Formation with Lasalocid A in Chloroform.” Inorganic Chemistry 37, no. 8 (January 1, 1998): 1906–12. https://doi.org/10.1021/ic971038o.
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    • Ghio, A. J., D. E. Taylor, J. G. Stonehuerner, C. A. Piantadosi, and A. L. Crumbliss. “The release of iron from different asbestos structures by hydrogen peroxide with concomitant O2 generation.” Biometals 11, no. 1 (January 1998): 41–47. https://doi.org/10.1023/a:1009257323963.
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    • Kraiter, D. C., O. Zak, P. Aisen, and A. L. Crumbliss. “A Determination of the Reduction Potentials for Diferric and C- and N-Lobe Monoferric Transferrins at Endosomal pH (5.8).” Inorganic Chemistry 37, no. 5 (January 1, 1998): 964–68. https://doi.org/10.1021/ic970644g.
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    • Crumbliss, A. L. “Preorganization of ferric alcaligin, Fe 2L 3. The first structure of a ferric dihydroxamate siderophore.” Chemtracts 10, no. 5 (December 1, 1997): 354–58.
    • Batinić-Haberle, I., I. Spasojević, and A. L. Crumbliss. “Solvent effect on second-sphere coordination of ferrioxamine B with substituted 18-crown-6 and 30-crown-10 crown ethers in dichloromethane as compared to chloroform.” Inorganica Chimica Acta 260, no. 1 (July 15, 1997): 35–41. https://doi.org/10.1016/S0020-1693(96)05528-4.
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    • Ghio, A. J., C. A. Piantadosi, and A. L. Crumbliss. “Hypothesis: iron chelation plays a vital role in neutrophilic inflammation.” Biometals 10, no. 2 (April 1997): 135–42. https://doi.org/10.1023/a:1018387308517.
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    • Zhao, J., R. W. Henkens, and A. L. Crumbliss. “Mediator-free amperometric determination of toxic substances based on their inhibition of immobilized horseradish peroxidase.” Biotechnology Progress 12, no. 5 (September 1996): 703–8. https://doi.org/10.1021/bp960056q.
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    • Batinic-Haberle, Ines, Ivan Spasojevic, and Alvin L. Crumbliss. “Second-Sphere Coordination of Ferrioxamine B and Association of Deferriferrioxamine B, CH(3)(CH(2))(4)NH(3)(+), NH(4)(+), K(+), and Mg(2+) with Synthetic Crown Ethers and the Natural Ionophores Valinomycin and Nonactin in Chloroform.” Inorg Chem 35, no. 8 (April 10, 1996): 2352–59. https://doi.org/10.1021/ic951414+.
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    • Batinic-Haberle, I., I. Spasojevié, and A. L. Crumbliss. “Second-Sphere Coordination of Ferrioxamine B and Association of Deferriferrioxamine B, CH₃(CH₂)4NH₃⁺, NH₄⁺, K⁺, and Mg²⁺ with Synthetic Crown Ethers and the Natural lonophores Valinomycin and Nonactin in Chloroform.” Inorganic Chemistry 35, no. 8 (1996): 2352–59.
    • Crumbliss, A. L., I. Batinić-Haberle, and I. Spasojević. “Molecular recognition of stable metal complexes through second-sphere coordination by macrocycles.” Pure and Applied Chemistry 68, no. 6 (January 1, 1996): 1225–30. https://doi.org/10.1351/pac199668061225.
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    • Zhao, J., J. P. O’Daly, R. W. Henkens, J. Stonehuerner, and A. L. Crumbliss. “A xanthine oxidase/colloidal gold enzyme electrode for amperometric biosensor applications.” Biosensors and Bioelectronics 11, no. 5 (January 1, 1996): 493–502. https://doi.org/10.1016/0956-5663(96)86786-8.
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    • Batinić-Haberle, I., I. Spasojević, R. A. Bartsch, and A. L. Crumbliss. “Stereochemical factors affecting second-sphere co-ordination of ferrioxamine B with cis-syn-cis and cis-anti-cis isomers of dicyclohexano-18-crown-6 in chloroform and a comparison with alkali-metal and ammonium cations.” Journal of the Chemical Society, Dalton Transactions, no. 15 (December 1, 1995): 2503–8. https://doi.org/10.1039/DT9950002503.
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    • Faulkner, K. M., C. Bonaventura, and A. L. Crumbliss. “A spectroelectrochemical method for differentiation of steric and electronic effects in hemoglobins and myoglobins.” The Journal of Biological Chemistry 270, no. 23 (June 1995): 13604–12. https://doi.org/10.1074/jbc.270.23.13604.
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    • Batinić-Haberle, I., and A. L. Crumbliss. “Influence of the Anion on the Stability of Second-Sphere Coordination of Ferrioxamine B with cis-Dicyclohexano-18-crown-6 in Chloroform.” Inorganic Chemistry 34, no. 4 (February 1, 1995): 928–32. https://doi.org/10.1021/ic00108a026.
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    • Caudle, M. T., C. D. Caldwell, and A. L. Crumbliss. “Dihydroxamic acid complexes of iron (III): ligand pKa and coordinated water hydrolysis constants.” Inorganica Chimica Acta 240, no. 1–2 (January 1, 1995): 519–25. https://doi.org/10.1016/0020-1693(95)04577-5.
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    • Schiffman, S. S., M. P. Manning, Z. S. Warwick, and A. L. Crumbliss. “Detection thresholds of potassium salts are related to the molar conductivity of the anion.” Brain Research Bulletin 37, no. 6 (January 1995): 623–26. https://doi.org/10.1016/0361-9230(95)00054-i.
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    • Caudle, M. T., R. D. Stevens, and A. L. Crumbliss. “A Monomer-to-Dimer Shift in a Series of 1:1 Ferric Dihydroxamates Probed by Electrospray Mass Spectrometry.” Inorganic Chemistry 33, no. 26 (December 1, 1994): 6111–15. https://doi.org/10.1021/ic00104a020.
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    • Ghio, A. J., J. Stonehuerner, M. P. Steele, and A. L. Crumbliss. “Phagocyte-generated superoxide reduces Fe3+ to displace it from the surface of asbestos.” Archives of Biochemistry and Biophysics 315, no. 2 (December 1994): 219–25. https://doi.org/10.1006/abbi.1994.1493.
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    • Caudle, M. T., L. P. Cogswell, and A. L. Crumbliss. “Mechanistic Studies on the Dissociation of Mono- and Bimetallic 1:1 Ferric Dihydroxamate Complexes: Probing Structural Effects in Siderophore Dissociation Reactions.” Inorganic Chemistry 33, no. 21 (October 1, 1994): 4759–73. https://doi.org/10.1021/ic00099a029.
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    • Caudle, M. T., and A. L. Crumbliss. “Dissociation Kinetics of (N-Methylacetohydroxamato)iron(III) Complexes: A Model for Probing Electronic and Structural Effects in the Dissociation of Siderophore Complexes.” Inorganic Chemistry 33, no. 18 (August 1, 1994): 4077–85. https://doi.org/10.1021/ic00096a037.
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    • Batinić-Haberle, I., I. Spasojević, and A. L. Crumbliss. “Hydrolysis of Ferrioxamine B in Aqueous Micellar Solution.” Inorganic Chemistry 33, no. 14 (July 1, 1994): 3151–58. https://doi.org/10.1021/ic00092a022.
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    • Spasojević, I., I. Batinfć-Haberle, P. L. Choo, and A. L. Crumbliss. “Supramolecular Assembly Formation of Ferrioxamine B and Its Al(III), Ga(III), and In(III) Analogues with Dicyclohexano-18-Crown-6 in Chloroform.” Journal of the American Chemical Society 116, no. 13 (June 1, 1994): 5714–21. https://doi.org/10.1021/ja00092a023.
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    • Ghio, A. J., T. P. Kennedy, J. G. Stonehuerner, A. L. Crumbliss, and J. R. Hoidal. “DNA strand breaks following in vitro exposure to asbestos increase with surface-complexed [Fe3+].” Archives of Biochemistry and Biophysics 311, no. 1 (May 1994): 13–18. https://doi.org/10.1006/abbi.1994.1202.
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    • Caudle, M. T., R. D. Stevens, and A. L. Crumbliss. “Electrospray Mass Spectrometry Study of 1:1 Ferric Dihydroxamates.” Inorganic Chemistry 33, no. 5 (March 1, 1994): 843–44. https://doi.org/10.1021/ic00083a001.
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    • Skelly, J. M., N. C. Morosoff, V. T. Stannett, and A. L. Crumbliss. “Formation of Plasma Polymer Thin Films Containing Reactive Metal Chelate Sites.” Chemistry of Materials 6, no. 2 (February 1, 1994): 227–33. https://doi.org/10.1021/cm00038a022.
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    • Chaubet, F., K. N. V. Duong, J. Courtieu, A. Gaudemer, A. Gref, A. L. Crumbliss, and M. T. Caudle. “Synthesis and structural studies of new polyhydroxamic iron(III) complexes for the use in nuclear magnetic resonance imaging. Part II: Study of the complexes formed in situ from hydroxamic acids.” Canadian Journal of Chemistry 72, no. 12 (1994): 2361–68.
    • Chaubet, F., K. Nguyen Van Duong, J. Courtieu, A. Gaudemer, A. Gref, A. L. Crumbliss, and M. T. Caudle. “Synthesis and structural studies of new polyhydroxamic iron(III) complexes for the use in nuclear magnetic resonance imaging. Part II: Study of the complexes formed in situ from hydroxamic acids.” Canadian Journal of Chemistry 72, no. 12 (January 1, 1994): 2361–68. https://doi.org/10.1139/v94-302.
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    • Faulkner, K. M., C. Bonaventura, and A. L. Crumbliss. “A spectroelectrochemical method for evaluating factors which regulate the redox potential of hemoglobins.” Inorganica Chimica Acta 226, no. 1–2 (January 1, 1994): 187–94. https://doi.org/10.1016/0020-1693(94)04086-9.
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    • Crumbliss, A. L., D. Cooke, J. Castillo, and P. Wisian-Neilson. “Redox Properties of Phosphazene Polymers with Pendant Ferrocene Groups.” Inorganic Chemistry 32, no. 26 (January 1, 1993): 6088–94. https://doi.org/10.1021/ic00078a029.
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    • Crumbliss, A. L., J. G. Stonehuerner, R. W. Henkens, J. Zhao, and J. P. O’Daly. “A carrageenan hydrogel stabilized colloidal gold multi-enzyme biosensor electrode utilizing immobilized horseradish peroxidase and cholesterol oxidase/cholesterol esterase to detect cholesterol in serum and whole blood.” Biosensors & Bioelectronics 8, no. 6 (January 1993): 331–37. https://doi.org/10.1016/0956-5663(93)85014-f.
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    • Skelly, J. M., N. C. Morosoff, V. T. Stannett, and A. L. Crumbliss. “Reversible Complexation of O2 to (meso-Tetraphenylporphyrinato)cobalt(II) Plasma Polymer and Sublimed Films at Room Temperature.” Inorganic Chemistry 32, no. 7 (January 1, 1993): 1306–8. https://doi.org/10.1021/ic00059a046.
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    • Ghio, A. J., T. P. Kennedy, A. R. Whorton, A. L. Crumbliss, G. E. Hatch, and J. R. Hoidal. “Role of surface complexed iron in oxidant generation and lung inflammation induced by silicates.” The American Journal of Physiology 263, no. 5 Pt 1 (November 1992): L511–18. https://doi.org/10.1152/ajplung.1992.263.5.l511.
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    • Crumbliss, A. L., S. C. Perine, J. Stonehuerner, K. R. Tubergen, J. Zhao, R. W. Henkens, and J. P. O’Daly. “Colloidal gold as a biocompatible immobilization matrix suitable for the fabrication of enzyme electrodes by electrodeposition.” Biotechnology and Bioengineering 40, no. 4 (August 1992): 483–90. https://doi.org/10.1002/bit.260400406.
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    • Zhao, J., R. W. Henkens, J. Stonehuerner, J. P. O’Daly, and A. L. Crumbliss. “Direct electron transfer at horseradish peroxidase-colloidal gold modified electrodes.” Journal of Electroanalytical Chemistry 327, no. 1–2 (June 10, 1992): 109–19. https://doi.org/10.1016/0022-0728(92)80140-Y.
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    • Clymer, S. D., N. C. Morosoff, and A. L. Crumbliss. “Triallylphosphine plasma polymerization and reaction of the product with volatile transition metal compounds.” Journal of Applied Polymer Science 45, no. 1 (January 1, 1992): 135–45. https://doi.org/10.1002/app.1992.070450116.
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    • Crumbliss, A. L., S. C. Perine, A. K. Edwards, and D. P. Rillema. “Characterization of carrageenan hydrogel electrode coatings with immobilized cationic metal complex redox couples.” Journal of Physical Chemistry 96, no. 3 (January 1, 1992): 1388–94. https://doi.org/10.1021/j100182a067.
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    • Morosoff, N. C., S. D. Clymer, and A. L. Crumbliss. “Preparation of a plasma polymer containing phosphine complexed nickel by concurrent nickel evaporation.” Journal of Applied Polymer Science 45, no. 1 (January 1, 1992): 147–58. https://doi.org/10.1002/app.1992.070450117.
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    • Stonehuerner, J. G., J. Zhoa, J. P. O’Daly, A. L. Crumbliss, and R. W. Henkens. “Comparison of colloidal gold electrode fabrication methods: the preparation of a horseradish peroxidase enzyme electrode.” Biosensors & Bioelectronics 7, no. 6 (January 1992): 421–28. https://doi.org/10.1016/0956-5663(92)85041-8.
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    • Rillema, D. P., A. K. Edwards, S. C. Perine, and A. L. Crumbliss. “Electrochemistry and Photocurrents of the Tris(bipyridine)ruthenium(II) and Methyl Viologen Cations Immobilized in Carrageenan Hydrogel.” Inorganic Chemistry 30, no. 23 (November 1, 1991): 4421–25. https://doi.org/10.1021/ic00023a026.
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    • McLachlan, K. L., and A. L. Crumbliss. “The effect of an applied potential on the activity of carbonic anhydrase immobilized on graphite rods.” Biotechnology and Bioengineering 37, no. 5 (March 1991): 491–96. https://doi.org/10.1002/bit.260370511.
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    • Chaubet, F., M. N. V. Duong, J. Courtieu, A. Gaudemer, A. Gref, and A. L. Crumbliss. “Synthesis and structural studies of new polyhydroxamic complexes of iron(III) that can be used in NMR. I. The preparation of ligands.” Canadian Journal of Chemistry 69, no. 7 (1991): 1107–16.
    • Chaubet, F., M. Nguyen Van Duong, J. Courtieu, A. Gaudemer, A. Gref, and A. L. Crumbliss. “Synthesis and structural studies of new polyhydroxamic complexes of iron(III) that can be used in NMR. I. The preparation of ligands.” Canadian Journal of Chemistry 69, no. 7 (January 1, 1991): 1107–16. https://doi.org/10.1139/v91-164.
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    • Schiffman, S. S., A. L. Crumbliss, Z. S. Warwick, and B. G. Graham. “Thresholds for sodium salts in young and elderly human subjects: Correlation with molar conductivity of anion.” Chemical Senses 15, no. 6 (December 1, 1990): 671–78. https://doi.org/10.1093/chemse/15.6.671.
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    • McLachlan, K. L., and A. L. Crumbliss. “The use of the methyl viologen neutral species as a mediator.” Journal of Electroanalytical Chemistry 295, no. 1–2 (November 26, 1990): 113–22. https://doi.org/10.1016/0022-0728(90)85009-T.
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    • Crumbliss, A. L. “Iron bioavailability and the coordination chemistry of hydroxamic acids.” Coordination Chemistry Reviews 105, no. C (November 1, 1990): 155–79. https://doi.org/10.1016/0010-8545(90)80021-K.
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    • Ghio, A. J., T. P. Kennedy, R. M. Schapira, A. L. Crumbliss, and J. R. Hoidal. “Hypothesis: is lung disease after silicate inhalation caused by oxidant generation?” Lancet (London, England) 336, no. 8721 (October 1990): 967–69. https://doi.org/10.1016/0140-6736(90)92421-d.
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    • O’Daly, J. P., A. L. Crumbliss, and R. W. Henkens. “Activity of carbonic anhydrase immobilized on porous silica beads in organic media.” Biotechnology and Applied Biochemistry 12, no. 1 (April 18, 1990): 11–19.
    • Crumbliss, A. L., K. L. McLachlan, J. N. Siedow, and S. P. Walton. “Electrochemistry of heat-extracted methanogenic bacterial cofactor F430.” Inorganica Chimica Acta 170, no. 2 (April 17, 1990): 161–63. https://doi.org/10.1016/S0020-1693(00)80470-3.
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    • Topping, R. J., L. D. Quin, and A. L. Crumbliss. “The influence of rigid cyclic phosphine ligands in cis-Rh(COD)-(phosphine)2⁺ on inner coordination shell dynamics and catalyzed olefin hydrogenation/isomerization.” Journal of Organometallic Chemistry 385, no. 1 (March 13, 1990): 131–45. https://doi.org/10.1016/0022-328X(90)87152-4.
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    • Chaubet, F., M. N. van duong, A. Gref, J. Courtieu, A. L. Crumbliss, A. Gaudemer, and P. M. Gross. “The design of magnetic resonance contrast agents: New iron (III) dihydroxamate complexes.” Tetrahedron Letters 31, no. 40 (January 1, 1990): 5729–32. https://doi.org/10.1016/S0040-4039(00)97943-7.
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    • Clymer, S. D., A. L. Crumbliss, and N. C. Morosoff. “Plasma polymers containing uniformly dispersed nickel.” Polymeric Materials Science and Engineering, Proceedings of the Acs Division of Polymeric Materials Science and Engineering 62 (January 1, 1990): 528–32.
    • Morosoff, N. C., and A. L. Crumbliss. “Preparation of plasma polymers containing ligated transition metal atoms.” Polymeric Materials Science and Engineering, Proceedings of the Acs Division of Polymeric Materials Science and Engineering 62 (January 1, 1990): 525–27.
    • Crumbliss, A. L., and J. M. Garrison. “A Comparison of Some Aspects of the Aqueous Coordination Chemistry of Aluminum(lll) and Iron(lll).” Comments on Inorganic Chemistry 8, no. 1–2 (September 1, 1988): 1–26. https://doi.org/10.1080/02603598808048670.
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    • Mark Garrison, J., and A. L. Crumbliss. “Experimental Determination of the ²⁷Al NMR Quadrupole Coupling Constant of the Hexaaquoaluminum Ion in Aqueous Perchloric Acid and Mixed Acetone-Aqueous Perchloric Acid Solution.” Inorganic Chemistry 27, no. 17 (August 1, 1988): 3058–60. https://doi.org/10.1021/ic00290a033.
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    • Crumbliss, A. L., K. L. McLachlan, J. P. O’Daly, and R. W. Henkens. “Preparation and activity of carbonic anhydrase immobilized on porous silica beads and graphite rods.” Biotechnology and Bioengineering 31, no. 8 (May 1988): 796–801. https://doi.org/10.1002/bit.260310806.
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    • Garrison, J. M., and A. L. Crumbliss. “Hydroxamic Acid Ligand-Exchange Kinetics at Hexaaquoaluminum Ion.” Inorganic Chemistry 26, no. 22 (November 1, 1987): 3660–64. https://doi.org/10.1021/ic00269a009.
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    • L. Crumbliss, A., J. M. Garrison, C. R. Bock, A. Schaaf, C. J. Bonaventura, and J. Bonaventura. “Synthesis and characterization of iron(llI) chelating analogues of siderophores on organic solid supports.” Inorganica Chimica Acta 133, no. 2 (October 15, 1987): 281–87. https://doi.org/10.1016/S0020-1693(00)87780-4.
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    • Mark Garrison, J., and A. L. Crumbliss. “Kinetics and mechanism of aluminum(III)/siderophore ligand exchange: mono(deferriferrioxamine B)aluminum(III) formation and dissociation in aqueous acid solution.” Inorganica Chimica Acta 138, no. 1 (January 1, 1987): 61–65. https://doi.org/10.1016/S0020-1693(00)81182-2.
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    • Crumbliss, A. L., H. A. O. Hill, and D. J. Page. “The electrochemistry of hexacyanoruthenate at carbon electrodes and the use of ruthenium compounds as mediators in the glucose/glucose oxidase system.” Journal of Electroanalytical Chemistry 206, no. 1–2 (July 10, 1986): 327–31. https://doi.org/10.1016/0022-0728(86)90280-9.
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    • Crumbliss, A. L., R. J. Topping, J. Szewczyk, A. T. McPhail, and L. D. Quin. “The synthesis, x-ray crystal structure, and solution characterization of a bis(diphosphine)-bridged dirhodium(I) complex containing a Rh2P4 six-membered ring.” Journal of the Chemical Society, Dalton Transactions, no. 9 (January 1, 1986): 1895–99. https://doi.org/10.1039/DT9860001895.
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    • Crumbliss, A. L., R. J. Topping, and L. D. Quin. “Retention of phosphorus configuration on forming irontetracarbonyl complexes with phosphines in the 9-phosphabicyclo[4.2.1]nonatriene and 7-phosphanorbornene systems.” Tetrahedron Letters 27, no. 8 (January 1, 1986): 889–92. https://doi.org/10.1016/S0040-4039(00)84129-5.
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    • Fish, L. L., and A. L. Crumbliss. “Comparison of the Kinetics, Mechanism, and Thermodynamics of Aqueous Iron(III) Chelation and Dissociation by Hydroxamic Oxo and Thio Acid Ligands.” Inorganic Chemistry 24, no. 14 (July 1, 1985): 2198–2204. https://doi.org/10.1021/ic00208a018.
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    • Brink, C. P., L. L. Fish, and A. L. Crumbliss. “Temperature-Dependent Acid Dissociation Constants (KaΔHa, ΔSa) for some C-Aryl Hydroxamic Acids: The Influence of C and N Substituents on Hydroxamate Anion Solvation in Aqueous Solution.” Journal of Organic Chemistry 50, no. 13 (January 1, 1985): 2277–81. https://doi.org/10.1021/jo00213a016.
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    • Crumbliss, A. L., P. S. Lugg, J. W. Childers, and R. A. Palmer. “Fourier transform infrared photothermal spectroscopic characterization of Prussian blue surface modified electrodes. Countercation effects.” Journal of Physical Chemistry 89, no. 3 (January 1, 1985): 482–88. https://doi.org/10.1021/j100249a023.
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    • Morosoff, N., R. Hague, S. D. Clymer, and A. L. Crumbliss. “Transition metal containing plasma polymers.” Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films 3, no. 6 (January 1, 1985): 2098–2101. https://doi.org/10.1116/1.572931.
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    • Morosoff, N., P. S. Lugg, D. L. Patel, and A. L. Crumbliss. “CHEMICAL PROPERTIES OF METALLATED PLASMA POLYMERS.” Applied Polymer Symposia, December 1, 1984, 83–97.
    • Morosoff, N., D. L. Patel, A. R. White, M. Umaña, A. L. Crumbliss, P. S. Lugg, and D. B. Brown. “Plasma polymerization of iron pentacarbonyl with C2 hydrocarbons.” Thin Solid Films 117, no. 1 (July 6, 1984): 33–58. https://doi.org/10.1016/0040-6090(84)90191-3.
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    • Morosoff, N., D. L. Patel, P. S. Lugg, and A. L. Crumbliss. “Preparation of tris(η⁵-cyclopentadienylcobaltmonocarbonyl) cluster complex by a plasma technique.” Inorganica Chimica Acta 83, no. 2 (March 15, 1984): 137–41. https://doi.org/10.1016/S0020-1693(00)82522-0.
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    • Brink, C. P., and A. L. Crumbliss. “Kinetics, mechanism, and thermodynamics of aqueous iron(III) chelation and dissociation: Influence of carbon and nitrogen substituents in hydroxamic acid ligands.” Inorganic Chemistry 23, no. 26 (January 1, 1984): 4708–18. https://doi.org/10.1021/ic00194a058.
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    • Crumblis, A. L., P. S. Lug, and N. Morosoff. “Alkali metal cation effects in a prussian blue surface-modified electrode.” Inorganic Chemistry 23, no. 26 (January 1, 1984): 4701–8. https://doi.org/10.1021/ic00194a057.
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    • Monzyk, B., and A. L. Crumbliss. “Factors that influence siderophoremediated iron bioavailability: catalysis of interligand iron (III) transfer from ferrioxamine B to EDTA by hydroxamic acids.” Journal of Inorganic Biochemistry 19, no. 1 (August 1983): 19–39. https://doi.org/10.1016/0162-0134(83)85010-7.
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    • Childers, J. W., A. L. Crumbliss, P. S. Lugg, R. A. Palmer, N. Morosoff, and D. L. Patel. “SPECTRAL CHARACTERIZATION OF REDOX-ACTIVE PRUSSIAN BLUE ON METALLATED PLASMA POLYMER SURFACE MODIFIED CARBON ELECTRODES USING PHOTOTHERMAL DETECTION.” Journal De Physique (Paris), Colloque 44, no. 10 (January 1, 1983). https://doi.org/10.1051/jphyscol:1983645.
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    • Crumbliss, A. L., P. S. Lugg, D. L. Patel, and N. Morosoff. “Use of a Metal-Containing Plasma Polymer Coating to Prepare a Prussian Blue Surface Modified Electrode.” Inorganic Chemistry 22, no. 24 (January 1, 1983): 3541–48. https://doi.org/10.1021/ic00166a012.
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    • Wilmarth, W. K., K. R. Ashley, J. C. Harmon, J. Fredericks, and A. L. Crumbliss. “Kinetics and mechanism of base aquation of chloroamminebis(dimethylglyoximato)cobalt(III) and chloropyridinebis(dimethylglyoximato)cobalt(III).” Coordination Chemistry Reviews 51, no. 2 (January 1, 1983): 225–42. https://doi.org/10.1016/0010-8545(83)85013-9.
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    • Morosoff, N., D. L. Patel, A. L. Crumbliss, and P. S. Lugg. “CHEMICAL PROPERTIES OF METALLATED PLASMA POLYMERS.” Organic Coatings and Applied Polymer Science Proceedings 47 (December 1, 1982): 318–22.
    • Brink, C. P., and A. L. Crumbliss. “Temperature-Dependent Acid Dissociation Constants (Ka, ΔHa, ΔSa) for a Series of Nitrogen-Substituted Hydroxamic Acids in Aqueous Solution.” Journal of Organic Chemistry 47, no. 7 (January 1, 1982): 1171–76. https://doi.org/10.1021/jo00346a005.
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    • Monzyk, B., and A. L. Crumbliss. “Kinetics and Mechanism of the Stepwise Dissociation of Iron(III) from Ferrioxamine B in Aqueous Acid.” Journal of the American Chemical Society 104, no. 18 (January 1, 1982): 4921–29. https://doi.org/10.1021/ja00382a031.
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    • Pinault, F. S., and A. L. Crumbliss. “Cobaloxime(II)-initiated coupling of α,α,α-trihalomethylbenzenes.” Journal of Organometallic Chemistry 215, no. 2 (July 28, 1981): 229–39. https://doi.org/10.1016/S0022-328X(00)80133-3.
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    • Monzyk, B., and A. L. Crumbliss. “Kinetics and mechanism of the final stage of ferrioxamine B aquation in aqueous acid.” Inorganica Chimica Acta 55, no. C (January 1, 1981). https://doi.org/10.1016/S0020-1693(00)90753-9.
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    • Quin, L. D., K. A. Mesch, F. S. B. Pinault, and A. L. Crumbliss. “Retention of stereospecific ³¹P chemical shift and coupling phenomena in a heterocyclic diphosphine upon complexation with a cobaloxime.” Inorganica Chimica Acta 53, no. C (January 1, 1981). https://doi.org/10.1016/S0020-1693(00)84803-3.
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    • Dufour, M. N., A. L. Crumbliss, G. Johnston, and A. Gaudemer. “Reaction of indoles with molecular oxygen catalyzed by metalloporphyrins.” Journal of Molecular Catalysis 7, no. 2 (January 1, 1980): 277–87. https://doi.org/10.1016/0304-5102(80)85025-5.
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    • Monzyk, B., and A. L. Crumbliss. “Acid Dissociation Constants (Ka) and Their Temperature Dependencies (AHa, ASa) for a Series of Carbon- and Nitrogen-Substituted Hydroxamic Acids in Aqueous Solution.” Journal of Organic Chemistry 45, no. 23 (January 1, 1980): 4670–75. https://doi.org/10.1021/jo01311a024.
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    • Bruce, M., and A. Crumbliss. “Mechanism of Ligand Substitution on High-Spin Iron(III) by Hydroxamic Acid Chelators. Thermodynamic and Kinetic Studies on the Formation and Dissociation of a Series of Monohydroxamatoiron(III) Complexes.” Journal of the American Chemical Society 101, no. 21 (September 1, 1979): 6203–13. https://doi.org/10.1021/ja00515a009.
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    • Ciskowski, J. M., and A. L. Crumbliss. “Synthesis and Characterization of Neutral Thiocyanato-and Selenocyanato-Bridged Cobaloximes.” Inorganic Chemistry 18, no. 3 (January 1, 1979): 638–46. https://doi.org/10.1021/ic50193a023.
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    • Pitt, C. G., G. Gupta, W. E. Estes, H. Rosenkrantz, J. J. Metterville, A. L. Crumbliss, R. A. Palmer, et al. “The selection and evaluation of new chelating agents for the treatment of iron overload.” The Journal of Pharmacology and Experimental Therapeutics 208, no. 1 (January 1979): 12–18.
    • Gaus, P. L., and A. L. Crumbliss. “Synthesis and Characterization of Neutral Cyano-Bridged Dicobaloximes. (Alkyl)cobaloxime-μ-cyano-(ligand)cobaloxime.” Inorganic Chemistry 15, no. 9 (September 1, 1976): 2080–86. https://doi.org/10.1021/ic50163a013.
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    • Crumbliss, A. L., and P. L. Gaus. “Synthesis of Monocyanocobaloximes.” Inorganic Chemistry 15, no. 3 (March 1, 1976): 737–39. https://doi.org/10.1021/ic50157a052.
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    • Gaus, P. L., and A. L. Crumbliss. “Carbon-13 Nuclear Magnetic Resonance Spectra of Cyanocobaloximes Containing Carbon-13-Labeled Cyanide.” Inorganic Chemistry 15, no. 3 (March 1, 1976): 739–41. https://doi.org/10.1021/ic50157a053.
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    • Crumbliss, A. L., M. E. McCabe, J. A. Dilts, and H. B. Herman. “An introductory chemistry synthesis and kinetics experiment: Utilizing a low cost linear-log output spectrophotometer modification.” Journal of Chemical Education 53, no. 8 (January 1, 1976): 528–30. https://doi.org/10.1021/ed053p528.
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    • Crumbliss, A. L., and L. J. Gestaut. “Short communication Electronic Effects on the rate of Oxidation of Substituted Phenanthroline Complexes of Copper(I) by Molecular Oxygen.” Journal of Coordination Chemistry 5, no. 2 (January 1, 1976): 109–11. https://doi.org/10.1080/00958977608075930.
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    • Crumbliss, A. L., and P. L. Gaus. “Intermolecular Hydrogen Bonding in Protonated Diacidocobaloximes.” Inorganic Chemistry 14, no. 11 (November 1, 1975): 2745–47. https://doi.org/10.1021/ic50153a030.
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    • Crumbliss, A. L., and A. T. Poulos. “Kinetics of Oxidation of a Cuprous 2,2′,2″-Terpyridine Complex by Molecular Oxygen.” Inorganic Chemistry 14, no. 7 (July 1, 1975): 1529–34. https://doi.org/10.1021/ic50149a017.
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    • Butterfield, D. A., A. L. Crumbliss, and D. B. Chesnut. “Radical decay kinetics in ferrocytochrome c model membranes. A spin label study.” Journal of the American Chemical Society 97, no. 6 (March 1975): 1388–93. https://doi.org/10.1021/ja00839a018.
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    • Crumbliss, A. L., and P. L. Gaus. “Synthesis and Characterization of Protonated Alkylcobaloximes and Related Compounds.” Inorganic Chemistry 14, no. 3 (March 1, 1975): 486–90. https://doi.org/10.1021/ic50145a007.
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    • Crumbliss, A. L., L. J. Gestaut, R. C. Rickard, and A. T. McPhail. “Preparation and X-ray crystal structure of a novel tetranuclear copper(I) ethylenethiourea cluster complex, μ4-ethylenethiourea-cyclo- tetrakis-μ-(ethylenethiourea)tetrakis[ethylenethioureacopper(I)] nitrate hexahydrate.” Journal of the Chemical Society, Chemical Communications, no. 14 (January 1, 1974): 545–46. https://doi.org/10.1039/C39740000545.
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    • Crumbliss, A. L., and P. L. Gaus. “The synthesis of neutral cyano bridged dicobaloximes.” Inorganic and Nuclear Chemistry Letters 10, no. 6 (January 1, 1974): 485–90. https://doi.org/10.1016/0020-1650(74)80071-1.
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    • Crumbliss, A. L., J. T. Bowman, P. L. Gaus, and A. T. McPhail. “Isolation and characterization of chloro(ethyl) dimethylglyoximatodimethylglyoximecobalt(III) hydrate. A protonated cobaloxime.” Journal of the Chemical Society, Chemical Communications, no. 13 (December 1, 1973): 415–16. https://doi.org/10.1039/C39730000415.
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    • Crumbliss, A. L., and F. Basolo. “Isomeric Tetracyanoethylene Adducts of N,N'-Ethylenebis(acetylacetoniminato)cobalt(II).” Inorganic Chemistry 10, no. 8 (August 1, 1971): 1676–80. https://doi.org/10.1021/ic50102a029.
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    • Crumbliss, A. L., and W. K. Wilmarth. “Substitution Kinetics of Alkylbis(dimethylglyoximato)aquocoball(III) in Aqueous Solution1 Sir.” Journal of the American Chemical Society 92, no. 8 (April 1, 1970): 2593–94. https://doi.org/10.1021/ja00711a088.
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    • Crumbliss, A. L., and F. Basolo. “Monomeric Oxygen Adducts of N,N′-Ethylenebis(acetylacetoniminato) ligandcobalt (II). Preparation and Properties.” Journal of the American Chemical Society 92, no. 1 (January 1, 1970): 55–60. https://doi.org/10.1021/ja00704a009.
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    • Crumbliss, A. L., and F. Basolo. “Monomeric cobalt-oxygen complexes.” Science (New York, N.Y.) 164, no. 3884 (June 1969): 1168–70. https://doi.org/10.1126/science.164.3884.1168.
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    • Hoeg, D. F., D. I. Lusk, and A. L. Crumbliss. “Preparation and Chemistry of α-Chloroalkyllithium Compounds. Their Role as Carbenoid Intermediates¹.” Journal of the American Chemical Society 87, no. 18 (January 1, 1965): 4147–55. https://doi.org/10.1021/ja01096a025.
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  • Book Sections

    • Crumbliss, A. L. “Aqueous solution equilibrium and kinetic studies of iron siderophore and model siderophore complexes.” In Handbook of Microbial Iron Chelates (1991), 177–234, 2017. https://doi.org/10.1201/9780203712368.
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  • Conference Papers

    • Crumbliss, A. L., R. W. Henkens, S. C. Perine, K. R. Tubergen, B. S. Kitchell, and J. Stonehuerner. “Amperometric glucose sensor fabricated from glucose oxidase and a mediator coimmobilized on a colloidal gold hydrogel electrode,” 187–94, 2017. https://doi.org/10.1201/9781315138404.
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• Scholarly, Clinical, & Service Activities
• 

  Presentations & Appearances

  • Moving Iron Across Membranes and Through Compartments in Biology. September 1, 2013  2013
  • Biocoordination Chemistry of Iron Siderophore Complexes. August 1, 2008  2008
  • Iron Transport Across the Periplasm in Neisseria. August 1, 2008  2008
  • Ferric Binding Protein: Moving Iron and Anions Across the Periplasm. July 1, 2008  2008
  • A Computational Model for Metal Ion Speciation in Multiple Component Systems Applied to Gallium Sequestration by a Bacterial Transferrin. April 1, 2008  2008
  • Characterization of Second Coordination Shell Host-Guest Assemblies and Binding Selectivities by Electrospray Ionization Mass Spectrometry (ESI-MS). April 1, 2008  2008
  • Characterization of Second Coordination Shell Host-Guest Assemblies and Binding Selectivities by Electrospray Ionization Mass Spectrometry (ESI-MS. April 1, 2008  2008
  • NADH Promotes Iron Release from a Siderophore Through Reduction. April 1, 2008  2008
  • Origin of the Root Effect in fish Hbs: Moderate proton-dependence of redox potentials suggests steric hindrance dominance. April 1, 2008  2008
• 

  Service to the Profession

  • American Chemical Society Joint Board Council Committee on Publications. January 15, 2013  2013
  • American Chemical Society National Councilor. January 15, 2013  2013
  • Consultant : Alderon Biosciences. January 15, 2013  2013
  • Consultant : Keryx Biopharmaceuticals. January 15, 2013  2013
  • Consultant : Rockwell Medical Technologies. January 15, 2013  2013
  • Consultant : Savage, Turner, Pinson & Karsman. January 15, 2013  2013
  • Consultant : The Proctor & Gamble Company. January 15, 2013  2013
  • Editorial Advisory Board, Metallomics. January 15, 2013  2013
  • Executive Committee, International Biometals Society. January 15, 2013  2013
  • Organizer, BioMetals 2014 conference. January 15, 2013  2013
  • Scientific Advisory Board : Rockwell Medical Technologies. January 15, 2013  2013
  • Discussion Leader : Gordon Research Conference, Environmental BioInorganic Chemistry (EBIC). September 22, 2008  2008

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