Alexander J. Hartemink

Preprint · July 10, 2026 Profiling genomic processes during the cell cycle is challenging because synchronized populations gradually lose synchrony as individual cells progress through the cycle at different rates and divide asymmetrically. Researchers have addressed this challeng ... Full text Link to item Cite

Genome-wide nucleosome and transcription factor responses to genetic perturbations reveal chromatin-mediated mechanisms of transcriptional regulation.

Preprint · May 26, 2024 Epigenetic mechanisms contribute to gene regulation by altering chromatin accessibility through changes in transcription factor (TF) and nucleosome occupancy throughout the genome. Despite numerous studies focusing on changes in gene expression, the intric ... Full text Link to item Cite

Single-cell multiome regression models identify functional and disease-associated enhancers and enable chromatin potential analysis

Preprint · June 14, 2023 Full text Cite

Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase.

Preprint · May 26, 2023 Full text Link to item Cite