Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Endocrinology Fellowship, University of Washington School of Medicine 2000 - 2003
  • M.S., University of Washington 2003
  • Internal Medicine Residency, Medicine, Duke University School of Medicine 1995 - 1998
  • M.D., Duke University School of Medicine 1995
• Research
• 

  Selected Grants

  • REGN1500 awarded by Regeneron Pharmaceuticals, Inc. 2018 - 2022
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Huang, G, Coviello, A, LaValley, MP, Ensrud, KE, Cauley, JA, Cawthon, PM, and Fredman, L. "Surgical Menopause and Frailty Risk in Community-Dwelling Older Women: Study of Osteoporotic Fractures." Journal of the American Geriatrics Society 66, no. 11 (November 2018): 2172-2177.  Full Text
    • Eriksson, AL, Perry, JRB, Coviello, AD, Delgado, GE, Ferrucci, L, Hoffman, AR, Huhtaniemi, IT, Ikram, MA, Karlsson, MK, Kleber, ME, Laughlin, GA, Liu, Y, Lorentzon, M, Lunetta, KL, Mellström, D, Murabito, JM, Murray, A, Nethander, M, Nielson, CM, Prokopenko, I, Pye, SR, Raffel, LJ, Rivadeneira, F, Srikanth, P, Stolk, L, Teumer, A, Travison, TG, Uitterlinden, AG, Vaidya, D, Vanderschueren, D, Zmuda, JM, März, W, Orwoll, ES, Ouyang, P, Vandenput, L, Wu, FCW, de Jong, FH, Bhasin, S, Kiel, DP, and Ohlsson, C. "Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men." The Journal of Clinical Endocrinology and Metabolism 103, no. 3 (March 2018): 991-1004.  Full Text
    • Stuver, SO, Lyons, J, Coviello, A, and Fredman, L. "Feasibility of 24-Hr Urine Collection for Measurement of Biomarkers in Community-Dwelling Older Adults." Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society 36, no. 11 (November 2017): 1393-1408.  Full Text
    • Jasuja, GK, Travison, TG, Murabito, JM, Davda, MN, Rose, AJ, Basaria, S, Coviello, A, Vasan, RS, D'Agostino, R, and Bhasin, S. "Circulating Estrogen Levels and Self-Reported Health and Mobility Limitation in Community-Dwelling Men of the Framingham Heart Study." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 72, no. 8 (August 2017): 1137-1142.  Full Text
    • Hinney, A, Kesselmeier, M, Jall, S, Volckmar, A-L, Föcker, M, Antel, J, GCAN, , WTCCC3, , Heid, IM, Winkler, TW, GIANT, , Grant, SFA, EGG, , Guo, Y, Bergen, AW, Kaye, W, Berrettini, W, Hakonarson, H, Price Foundation Collaborative Group, , Children’s Hospital of Philadelphia/Price Foundation, , Herpertz-Dahlmann, B, de Zwaan, M, Herzog, W, Ehrlich, S, Zipfel, S, Egberts, KM, Adan, R, Brandys, M, van Elburg, A, Boraska Perica, V, Franklin, CS, Tschöp, MH, Zeggini, E, Bulik, CM, Collier, D, Scherag, A, Müller, TD, and Hebebrand, J. "Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index." Molecular Psychiatry 22, no. 2 (February 2017): 192-201.  Full Text
    • Lunetta, KL, Day, FR, Sulem, P, Ruth, KS, Tung, JY, Hinds, DA, Esko, T, Elks, CE, Altmaier, E, He, C, Huffman, JE, Mihailov, E, Porcu, E, Robino, A, Rose, LM, Schick, UM, Stolk, L, Teumer, A, Thompson, DJ, Traglia, M, Wang, CA, Yerges-Armstrong, LM, Antoniou, AC, Barbieri, C, Coviello, AD, Cucca, F, Demerath, EW, Dunning, AM, Gandin, I, Grove, ML, Gudbjartsson, DF, Hocking, LJ, Hofman, A, Huang, J, Jackson, RD, Karasik, D, Kriebel, J, Lange, EM, Lange, LA, Langenberg, C, Li, X, Luan, J, Mägi, R, Morrison, AC, Padmanabhan, S, Pirie, A, Polasek, O, Porteous, D, Reiner, AP, Rivadeneira, F, Rudan, I, Sala, CF, Schlessinger, D, Scott, RA, Stöckl, D, Visser, JA, Völker, U, Vozzi, D, Wilson, JG, Zygmunt, M, Boerwinkle, E, Buring, JE, Crisponi, L, Easton, DF, Hayward, C, Hu, FB, Liu, S, Metspalu, A, Pennell, CE, Ridker, PM, Strauch, K, Streeten, EA, Toniolo, D, Uitterlinden, AG, Ulivi, S, Völzke, H, Wareham, NJ, Wellons, M, Franceschini, N, Chasman, DI, Thorsteinsdottir, U, Murray, A, Stefansson, K, Murabito, JM, Ong, KK, and Perry, JRB. "Corrigendum: Rare coding variants and X-linked loci associated with age at menarche." Nature Communications 6 (December 17, 2015).  Full Text
    • Day, FR, Ruth, KS, Thompson, DJ, Lunetta, KL, Pervjakova, N, Chasman, DI, Stolk, L, Finucane, HK, Sulem, P, Bulik-Sullivan, B, Esko, T, Johnson, AD, Elks, CE, Franceschini, N, He, C, Altmaier, E, Brody, JA, Franke, LL, Huffman, JE, Keller, MF, McArdle, PF, Nutile, T, Porcu, E, Robino, A, Rose, LM, Schick, UM, Smith, JA, Teumer, A, Traglia, M, Vuckovic, D, Yao, J, Zhao, W, Albrecht, E, Amin, N, Corre, T, Hottenga, JJ, Mangino, M, Smith, AV, Tanaka, T, Abecasis, GR, Andrulis, IL, Anton-Culver, H, Antoniou, AC, Arndt, V, Arnold, AM, Barbieri, C, Beckmann, MW, Beeghly-Fadiel, A, Benitez, J, Bernstein, L, Bielinski, SJ, Blomqvist, C, Boerwinkle, E, Bogdanova, NV, Bojesen, SE, Bolla, MK, Borresen-Dale, AL, Boutin, TS, Brauch, H, Brenner, H, Brüning, T, Burwinkel, B, Campbell, A, Campbell, H, Chanock, SJ, Chapman, JR, Ida Chen, YD, Chenevix-Trench, G, Couch, FJ, Coviello, AD, Cox, A, Czene, K, Darabi, H, De Vivo, I, Demerath, EW, Dennis, J, Devilee, P, Dörk, T, Dos-Santos-Silva, I, Dunning, AM, Eicher, JD, Fasching, PA, Faul, JD, Figueroa, J, Flesch-Janys, D, Gandin, I, Garcia, ME, Garciá-Closas, M, Giles, GG, Girotto, GG, Goldberg, MS, González-Neira, A, Goodarzi, MO, Grove, ML, Gudbjartsson, DF, Guénel, P, Guo, X, Haiman, CA, Hall, P, and Hamann, U. "Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair." Obstetrical and Gynecological Survey 70, no. 12 (December 1, 2015): 758-762.  Full Text
    • Day, FR, Ruth, KS, Thompson, DJ, Lunetta, KL, Pervjakova, N, Chasman, DI, Stolk, L, Finucane, HK, Sulem, P, Bulik-Sullivan, B, Esko, T, Johnson, AD, Elks, CE, Franceschini, N, He, C, Altmaier, E, Brody, JA, Franke, LL, Huffman, JE, Keller, MF, McArdle, PF, Nutile, T, Porcu, E, Robino, A, Rose, LM, Schick, UM, Smith, JA, Teumer, A, Traglia, M, Vuckovic, D, Yao, J, Zhao, W, Albrecht, E, Amin, N, Corre, T, Hottenga, J-J, Mangino, M, Smith, AV, Tanaka, T, Abecasis, G, Andrulis, IL, Anton-Culver, H, Antoniou, AC, Arndt, V, Arnold, AM, Barbieri, C, Beckmann, MW, Beeghly-Fadiel, A, Benitez, J, Bernstein, L, Bielinski, SJ, Blomqvist, C, Boerwinkle, E, Bogdanova, NV, Bojesen, SE, Bolla, MK, Borresen-Dale, A-L, Boutin, TS, Brauch, H, Brenner, H, Brüning, T, Burwinkel, B, Campbell, A, Campbell, H, Chanock, SJ, Chapman, JR, Chen, Y-DI, Chenevix-Trench, G, Couch, FJ, Coviello, AD, Cox, A, Czene, K, Darabi, H, De Vivo, I, Demerath, EW, Dennis, J, Devilee, P, Dörk, T, Dos-Santos-Silva, I, Dunning, AM, Eicher, JD, Fasching, PA, Faul, JD, Figueroa, J, Flesch-Janys, D, Gandin, I, Garcia, ME, García-Closas, M, Giles, GG, Girotto, GG, Goldberg, MS, González-Neira, A, Goodarzi, MO, Grove, ML, Gudbjartsson, DF, Guénel, P, Guo, X, Haiman, CA, Hall, P, Hamann, U, Henderson, BE, Hocking, LJ, Hofman, A, Homuth, G, Hooning, MJ, Hopper, JL, Hu, FB, Huang, J, Humphreys, K, Hunter, DJ, Jakubowska, A, Jones, SE, Kabisch, M, Karasik, D, Knight, JA, Kolcic, I, Kooperberg, C, Kosma, V-M, Kriebel, J, Kristensen, V, Lambrechts, D, Langenberg, C, Li, J, Li, X, Lindström, S, Liu, Y, Luan, J, Lubinski, J, Mägi, R, Mannermaa, A, Manz, J, Margolin, S, Marten, J, Martin, NG, Masciullo, C, Meindl, A, Michailidou, K, Mihailov, E, Milani, L, Milne, RL, Müller-Nurasyid, M, Nalls, M, Neale, BM, Nevanlinna, H, Neven, P, Newman, AB, Nordestgaard, BG, Olson, JE, Padmanabhan, S, Peterlongo, P, Peters, U, Petersmann, A, Peto, J, Pharoah, PDP, Pirastu, NN, Pirie, A, Pistis, G, Polasek, O, Porteous, D, Psaty, BM, Pylkäs, K, Radice, P, Raffel, LJ, Rivadeneira, F, Rudan, I, Rudolph, A, Ruggiero, D, Sala, CF, Sanna, S, Sawyer, EJ, Schlessinger, D, Schmidt, MK, Schmidt, F, Schmutzler, RK, Schoemaker, MJ, Scott, RA, Seynaeve, CM, Simard, J, Sorice, R, Southey, MC, Stöckl, D, Strauch, K, Swerdlow, A, Taylor, KD, Thorsteinsdottir, U, Toland, AE, Tomlinson, I, Truong, T, Tryggvadottir, L, Turner, ST, Vozzi, D, Wang, Q, Wellons, M, Willemsen, G, Wilson, JF, Winqvist, R, Wolffenbuttel, BBHR, Wright, AF, Yannoukakos, D, Zemunik, T, Zheng, W, Zygmunt, M, Bergmann, S, Boomsma, DI, Buring, JE, Ferrucci, L, Montgomery, GW, Gudnason, V, Spector, TD, van Duijn, CM, Alizadeh, BZ, Ciullo, M, Crisponi, L, Easton, DF, Gasparini, PP, Gieger, C, Harris, TB, Hayward, C, Kardia, SLR, Kraft, P, McKnight, B, Metspalu, A, Morrison, AC, Reiner, AP, Ridker, PM, Rotter, JI, Toniolo, D, Uitterlinden, AG, Ulivi, S, Völzke, H, Wareham, NJ, Weir, DR, Yerges-Armstrong, LM, PRACTICAL consortium, , kConFab Investigators, , AOCS Investigators, , Generation Scotland, , EPIC-InterAct Consortium, , LifeLines Cohort Study, , Price, AL, Stefansson, K, Visser, JA, Ong, KK, Chang-Claude, J, Murabito, JM, Perry, JRB, and Murray, A. "Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair." Nature Genetics 47, no. 11 (November 2015): 1294-1303.  Full Text
    • Lunetta, KL, Day, FR, Sulem, P, Ruth, KS, Tung, JY, Hinds, DA, Esko, T, Elks, CE, Altmaier, E, He, C, Huffman, JE, Mihailov, E, Porcu, E, Robino, A, Rose, LM, Schick, UM, Stolk, L, Teumer, A, Thompson, DJ, Traglia, M, Wang, CA, Yerges-Armstrong, LM, Antoniou, AC, Barbieri, C, Coviello, AD, Cucca, F, Demerath, EW, Dunning, AM, Gandin, I, Grove, ML, Gudbjartsson, DF, Hocking, LJ, Hofman, A, Huang, J, Jackson, RD, Karasik, D, Kriebel, J, Lange, EM, Lange, LA, Langenberg, C, Li, X, Luan, J, Mägi, R, Morrison, AC, Padmanabhan, S, Pirie, A, Polasek, O, Porteous, D, Reiner, AP, Rivadeneira, F, Rudan, I, Sala, CF, Schlessinger, D, Scott, RA, Stöckl, D, Visser, JA, Völker, U, Vozzi, D, Wilson, JG, Zygmunt, M, EPIC-InterAct Consortium, , Generation Scotland, , Boerwinkle, E, Buring, JE, Crisponi, L, Easton, DF, Hayward, C, Hu, FB, Liu, S, Metspalu, A, Pennell, CE, Ridker, PM, Strauch, K, Streeten, EA, Toniolo, D, Uitterlinden, AG, Ulivi, S, Völzke, H, Wareham, NJ, Wellons, M, Franceschini, N, Chasman, DI, Thorsteinsdottir, U, Murray, A, Stefansson, K, Murabito, JM, Ong, KK, and Perry, JRB. "Rare coding variants and X-linked loci associated with age at menarche." Nature Communications 6 (August 4, 2015): 7756-null.  Full Text
    • Basaria, S, Harman, SM, Travison, TG, Hodis, H, Tsitouras, P, Budoff, M, Pencina, KM, Vita, J, Dzekov, C, Mazer, NA, Coviello, AD, Knapp, PE, Hally, K, Pinjic, E, Yan, M, Storer, TW, and Bhasin, S. "Effects of Testosterone Administration for 3 Years on Subclinical Atherosclerosis Progression in Older Men With Low or Low-Normal Testosterone Levels: A Randomized Clinical Trial." Jama 314, no. 6 (August 2015): 570-581.  Full Text
    • Perry, JR, Day, F, Elks, CE, Sulem, P, Thompson, DJ, Ferreira, T, He, C, Chasman, DI, Esko, T, Thorleifsson, G, Albrecht, E, Ang, WQ, Corre, T, Cousminer, DL, Feenstra, B, Franceschini, N, Ganna, A, Johnson, AD, Kjellqvist, S, Lunetta, KL, McMahon, G, Nolte, IM, Paternoster, L, Porcu, E, Smith, AV, Stolk, L, Teumer, A, Tšernikova, N, Tikkanen, E, Ulivi, S, Wagner, EK, Amin, N, Bierut, LJ, Byrne, EM, Hottenga, J-J, Koller, DL, Mangino, M, Pers, TH, Yerges-Armstrong, LM, Zhao, JH, Andrulis, IL, Anton-Culver, H, Atsma, F, Bandinelli, S, Beckmann, MW, Benitez, J, Blomqvist, C, Bojesen, SE, Bolla, MK, Bonanni, B, Brauch, H, Brenner, H, Buring, JE, Chang-Claude, J, Chanock, S, Chen, J, Chenevix-Trench, G, Collée, JM, Couch, FJ, Couper, D, Coveillo, AD, Cox, A, Czene, K, D'adamo, AP, Smith, GD, De Vivo, I, Demerath, EW, Dennis, J, Devilee, P, Dieffenbach, AK, Dunning, AM, Eiriksdottir, G, Eriksson, JG, Fasching, PA, Ferrucci, L, Flesch-Janys, D, Flyger, H, Foroud, T, Franke, L, Garcia, ME, García-Closas, M, Geller, F, de Geus, EE, Giles, GG, Gudbjartsson, DF, Gudnason, V, Guénel, P, Guo, S, Hall, P, Hamann, U, Haring, R, Hartman, CA, Heath, AC, Hofman, A, Hooning, MJ, Hopper, JL, Hu, FB, Hunter, DJ, Karasik, D, Kiel, DP, Knight, JA, Kosma, V-M, Kutalik, Z, Lai, S, Lambrechts, D, Lindblom, A, Mägi, R, Magnusson, PK, Mannermaa, A, Martin, NG, Masson, G, McArdle, PF, McArdle, WL, Melbye, M, Michailidou, K, Mihailov, E, Milani, L, Milne, RL, Nevanlinna, H, Neven, P, Nohr, EA, Oldehinkel, AJ, Oostra, BA, Palotie, A, Peacock, M, Pedersen, NL, Peterlongo, P, Peto, J, Pharoah, PD, Postma, DS, Pouta, A, Pylkäs, K, Radice, P, Ring, S, Rivadeneira, F, Robino, A, Rose, LM, Rudolph, A, Salomaa, V, Sanna, S, Schlessinger, D, Schmidt, MK, Southey, MC, Sovio, U, Stampfer, MJ, Stöckl, D, Storniolo, AM, Timpson, NJ, Tyrer, J, Visser, JA, Vollenweider, P, Völzke, H, Waeber, G, Waldenberger, M, Wallaschofski, H, Wang, Q, Willemsen, G, Winqvist, R, Wolffenbuttel, BH, Wright, MJ, Australian Ovarian Cancer Study, , GENICA Network, , kConFab, , LifeLines Cohort Study, , InterAct Consortium, , Early Growth Genetics (EGG) Consortium, , Boomsma, DI, Econs, MJ, Khaw, K-T, Loos, RJ, McCarthy, MI, Montgomery, GW, Rice, JP, Streeten, EA, Thorsteinsdottir, U, van Duijn, CM, Alizadeh, BZ, Bergmann, S, Boerwinkle, E, Boyd, HA, Crisponi, L, Gasparini, P, Gieger, C, Harris, TB, Ingelsson, E, Järvelin, M-R, Kraft, P, Lawlor, D, Metspalu, A, Pennell, CE, Ridker, PM, Snieder, H, Sørensen, TI, Spector, TD, Strachan, DP, Uitterlinden, AG, Wareham, NJ, Widen, E, Zygmunt, M, Murray, A, Easton, DF, Stefansson, K, Murabito, JM, and Ong, KK. "Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche." Nature 514, no. 7520 (October 2014): 92-97.  Full Text
    • Magnani, JW, Moser, CB, Murabito, JM, Sullivan, LM, Wang, N, Ellinor, PT, Vasan, RS, Benjamin, EJ, and Coviello, AD. "Association of sex hormones, aging, and atrial fibrillation in men: the Framingham Heart Study." Circulation. Arrhythmia and Electrophysiology 7, no. 2 (April 2014): 307-312.  Full Text
    • Juang, PS, Peng, S, Allehmazedeh, K, Shah, A, Coviello, AD, and Herbst, KL. "Testosterone with dutasteride, but not anastrazole, improves insulin sensitivity in young obese men: a randomized controlled trial." The Journal of Sexual Medicine 11, no. 2 (February 2014): 563-573.  Full Text
    • Travison, TG, Zhuang, WV, Lunetta, KL, Karasik, D, Bhasin, S, Kiel, DP, Coviello, AD, and Murabito, JM. "The heritability of circulating testosterone, oestradiol, oestrone and sex hormone binding globulin concentrations in men: the Framingham Heart Study." Clinical Endocrinology 80, no. 2 (February 2014): 277-282.  Full Text
    • Mott, MM, Kitos, NR, and Coviello, AD. "Practice patterns in screening for metabolic disease in women with pcos of diverse race-ethnic backgrounds." Endocrine Practice 20, no. 9 (January 1, 2014): 855-863.  Full Text
    • Jasuja, GK, Travison, TG, Davda, M, Rose, AJ, Zhang, A, Kushnir, MM, Rockwood, AL, Meikle, W, Coviello, AD, D'Agostino, R, Vasan, RS, and Bhasin, S. "Circulating estrone levels are associated prospectively with diabetes risk in men of the Framingham Heart Study." Diabetes Care 36, no. 9 (September 2013): 2591-2596.  Full Text
    • Jasuja, GK, Travison, TG, Davda, M, Murabito, JM, Basaria, S, Zhang, A, Kushnir, MM, Rockwood, AL, Meikle, W, Pencina, MJ, Coviello, A, Rose, AJ, D'Agostino, R, Vasan, RS, and Bhasin, S. "Age trends in estradiol and estrone levels measured using liquid chromatography tandem mass spectrometry in community-dwelling men of the Framingham Heart Study." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 68, no. 6 (June 2013): 733-740.  Full Text
    • Haring, R, Teng, Z, Xanthakis, V, Coviello, A, Sullivan, L, Bhasin, S, Murabito, JM, Wallaschofski, H, and Vasan, RS. "Association of sex steroids, gonadotrophins, and their trajectories with clinical cardiovascular disease and all-cause mortality in elderly men from the Framingham Heart Study." Clinical Endocrinology 78, no. 4 (April 2013): 629-634.  Full Text
    • Haring, R, Xanthakis, V, Coviello, A, Sullivan, L, Bhasin, S, Wallaschofski, H, Murabito, JM, and Vasan, RS. "Clinical correlates of sex steroids and gonadotropins in men over the late adulthood: the Framingham Heart Study." International Journal of Andrology 35, no. 6 (December 2012): 775-782.  Full Text
    • Huang, G, and Coviello, A. "Clinical update on screening, diagnosis and management of metabolic disorders and cardiovascular risk factors associated with polycystic ovary syndrome." Current Opinion in Endocrinology, Diabetes, and Obesity 19, no. 6 (December 2012): 512-519. (Review)  Full Text
    • Stolk, L, Perry, JRB, Chasman, DI, He, C, Mangino, M, Sulem, P, Barbalic, M, Broer, L, Byrne, EM, Ernst, F, Esko, T, Franceschini, N, Gudbjartsson, DF, Hottenga, J-J, Kraft, P, McArdle, PF, Porcu, E, Shin, S-Y, Smith, AV, van Wingerden, S, Zhai, G, Zhuang, WV, Albrecht, E, Alizadeh, BZ, Aspelund, T, Bandinelli, S, Lauc, LB, Beckmann, JS, Boban, M, Boerwinkle, E, Broekmans, FJ, Burri, A, Campbell, H, Chanock, SJ, Chen, C, Cornelis, MC, Corre, T, Coviello, AD, d'Adamo, P, Davies, G, de Faire, U, de Geus, EJC, Deary, IJ, Dedoussis, GVZ, Deloukas, P, Ebrahim, S, Eiriksdottir, G, Emilsson, V, Eriksson, JG, Fauser, BCJM, Ferreli, L, Ferrucci, L, Fischer, K, Folsom, AR, Garcia, ME, Gasparini, P, Gieger, C, Glazer, N, Grobbee, DE, Hall, P, Haller, T, Hankinson, SE, Hass, M, Hayward, C, Heath, AC, Hofman, A, Ingelsson, E, Janssens, ACJW, Johnson, AD, Karasik, D, Kardia, SLR, Keyzer, J, Kiel, DP, Kolcic, I, Kutalik, Z, Lahti, J, Lai, S, Laisk, T, Laven, JSE, Lawlor, DA, Liu, J, Lopez, LM, Louwers, YV, Magnusson, PKE, Marongiu, M, Martin, NG, Klaric, IM, Masciullo, C, McKnight, B, Medland, SE, Melzer, D, Mooser, V, Navarro, P, Newman, AB, Nyholt, DR, Onland-Moret, NC, Palotie, A, Paré, G, Parker, AN, Pedersen, NL, Peeters, PHM, Pistis, G, Plump, AS, Polasek, O, Pop, VJM, Psaty, BM, Räikkönen, K, Rehnberg, E, Rotter, JI, Rudan, I, Sala, C, Salumets, A, Scuteri, A, Singleton, A, Smith, JA, Snieder, H, Soranzo, N, Stacey, SN, Starr, JM, Stathopoulou, MG, Stirrups, K, Stolk, RP, Styrkarsdottir, U, Sun, YV, Tenesa, A, Thorand, B, Toniolo, D, Tryggvadottir, L, Tsui, K, Ulivi, S, van Dam, RM, van der Schouw, YT, van Gils, CH, van Nierop, P, Vink, JM, Visscher, PM, Voorhuis, M, Waeber, G, Wallaschofski, H, Wichmann, HE, Widen, E, Wijnands-van Gent, CJM, Willemsen, G, Wilson, JF, Wolffenbuttel, BHR, Wright, AF, Yerges-Armstrong, LM, Zemunik, T, Zgaga, L, Zillikens, MC, Zygmunt, M, LifeLines Cohort Study, , Arnold, AM, Boomsma, DI, Buring, JE, Crisponi, L, Demerath, EW, Gudnason, V, Harris, TB, Hu, FB, Hunter, DJ, Launer, LJ, Metspalu, A, Montgomery, GW, Oostra, BA, Ridker, PM, Sanna, S, Schlessinger, D, Spector, TD, Stefansson, K, Streeten, EA, Thorsteinsdottir, U, Uda, M, Uitterlinden, AG, van Duijn, CM, Völzke, H, Murray, A, Murabito, JM, Visser, JA, and Lunetta, KL. "Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways." Nature Genetics 44, no. 3 (January 22, 2012): 260-268.  Full Text
    • Coviello, AD, Haring, R, Wellons, M, Vaidya, D, Lehtimäki, T, Keildson, S, Lunetta, KL, He, C, Fornage, M, Lagou, V, Mangino, M, Onland-Moret, NC, Chen, B, Eriksson, J, Garcia, M, Liu, YM, Koster, A, Lohman, K, Lyytikäinen, L-P, Petersen, A-K, Prescott, J, Stolk, L, Vandenput, L, Wood, AR, Zhuang, WV, Ruokonen, A, Hartikainen, A-L, Pouta, A, Bandinelli, S, Biffar, R, Brabant, G, Cox, DG, Chen, Y, Cummings, S, Ferrucci, L, Gunter, MJ, Hankinson, SE, Martikainen, H, Hofman, A, Homuth, G, Illig, T, Jansson, J-O, Johnson, AD, Karasik, D, Karlsson, M, Kettunen, J, Kiel, DP, Kraft, P, Liu, J, Ljunggren, Ö, Lorentzon, M, Maggio, M, Markus, MRP, Mellström, D, Miljkovic, I, Mirel, D, Nelson, S, Morin Papunen, L, Peeters, PHM, Prokopenko, I, Raffel, L, Reincke, M, Reiner, AP, Rexrode, K, Rivadeneira, F, Schwartz, SM, Siscovick, D, Soranzo, N, Stöckl, D, Tworoger, S, Uitterlinden, AG, van Gils, CH, Vasan, RS, Wichmann, H-E, Zhai, G, Bhasin, S, Bidlingmaier, M, Chanock, SJ, De Vivo, I, Harris, TB, Hunter, DJ, Kähönen, M, Liu, S, Ouyang, P, Spector, TD, van der Schouw, YT, Viikari, J, Wallaschofski, H, McCarthy, MI, Frayling, TM, Murray, A, Franks, S, Järvelin, M-R, de Jong, FH, Raitakari, O, Teumer, A, Ohlsson, C, Murabito, JM, and Perry, JRB. "A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation." Plos Genetics 8, no. 7 (January 2012): e1002805-null.  Full Text
    • Haring, R, Travison, TG, Bhasin, S, Vasan, RS, Wallaschofski, H, Davda, MN, Coviello, A, and Murabito, JM. "Relation between sex hormone concentrations, peripheral arterial disease, and change in ankle-brachial index: findings from the Framingham Heart Study." The Journal of Clinical Endocrinology and Metabolism 96, no. 12 (December 2011): 3724-3732.  Full Text
    • Bhasin, S, Jasjua, GK, Pencina, M, D'Agostino, R, Coviello, AD, Vasan, RS, and Travison, TG. "Sex hormone-binding globulin, but not testosterone, is associated prospectively and independently with incident metabolic syndrome in men: the framingham heart study." Diabetes Care 34, no. 11 (November 2011): 2464-2470.  Full Text
    • Cheng, S, Fox, CS, Larson, MG, Massaro, JM, McCabe, EL, Khan, AM, Levy, D, Hoffmann, U, O'Donnell, CJ, Miller, KK, Newton-Cheh, C, Coviello, AD, Bhasin, S, Vasan, RS, and Wang, TJ. "Relation of visceral adiposity to circulating natriuretic peptides in ambulatory individuals." The American Journal of Cardiology 108, no. 7 (October 2011): 979-984.  Full Text
    • Khan, AM, Cheng, S, Magnusson, M, Larson, MG, Newton-Cheh, C, McCabe, EL, Coviello, AD, Florez, JC, Fox, CS, Levy, D, Robins, SJ, Arora, P, Bhasin, S, Lam, CSP, Vasan, RS, Melander, O, and Wang, TJ. "Cardiac natriuretic peptides, obesity, and insulin resistance: evidence from two community-based studies." The Journal of Clinical Endocrinology and Metabolism 96, no. 10 (October 2011): 3242-3249.  Full Text
    • Travison, TG, Basaria, S, Storer, TW, Jette, AM, Miciek, R, Farwell, WR, Choong, K, Lakshman, K, Mazer, NA, Coviello, AD, Knapp, PE, Ulloor, J, Zhang, A, Brooks, B, Nguyen, A-H, Eder, R, LeBrasseur, N, Elmi, A, Appleman, E, Hede-Brierley, L, Bhasin, G, Bhatia, A, Lazzari, A, Davis, S, Ni, P, Collins, L, and Bhasin, S. "Clinical meaningfulness of the changes in muscle performance and physical function associated with testosterone administration in older men with mobility limitation." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 66, no. 10 (October 2011): 1090-1099.  Full Text
    • Coviello, AD, Zhuang, WV, Lunetta, KL, Bhasin, S, Ulloor, J, Zhang, A, Karasik, D, Kiel, DP, Vasan, RS, and Murabito, JM. "Circulating testosterone and SHBG concentrations are heritable in women: the Framingham Heart Study." The Journal of Clinical Endocrinology and Metabolism 96, no. 9 (September 2011): E1491-E1495.  Full Text
    • Lam, CSP, Cheng, S, Choong, K, Larson, MG, Murabito, JM, Newton-Cheh, C, Bhasin, S, McCabe, EL, Miller, KK, Redfield, MM, Vasan, RS, Coviello, AD, and Wang, TJ. "Influence of sex and hormone status on circulating natriuretic peptides." Journal of the American College of Cardiology 58, no. 6 (August 2011): 618-626.  Full Text
    • Bhasin, S, Pencina, M, Jasuja, GK, Travison, TG, Coviello, A, Orwoll, E, Wang, PY, Nielson, C, Wu, F, Tajar, A, Labrie, F, Vesper, H, Zhang, A, Ulloor, J, Singh, R, D'Agostino, R, and Vasan, RS. "Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the framingham heart study and applied to three geographically distinct cohorts." Journal of Clinical Endocrinology and Metabolism 96, no. 8 (2011): 2430-2439.  Full Text
    • Elks, CE, Perry, JRB, Sulem, P, Chasman, DI, Franceschini, N, He, C, Lunetta, KL, Visser, JA, Byrne, EM, Cousminer, DL, Gudbjartsson, DF, Esko, T, Feenstra, B, Hottenga, JJ, Koller, DL, Kutalik, Z, Lin, P, Mangino, M, Marongiu, M, McArdle, PF, Smith, AV, Stolk, L, Van Wingerden, SH, Zhao, JH, Albrecht, E, Corre, T, Ingelsson, E, Hayward, C, Magnusson, PKE, Smith, EN, Ulivi, S, Warrington, NM, Zgaga, L, Alavere, H, Amin, N, Aspelund, T, Bandinelli, S, Barroso, I, Berenson, GS, Bergmann, S, Blackburn, H, Boerwinkle, E, Buring, JE, Busonero, F, Campbell, H, Chanock, SJ, Chen, W, Cornelis, MC, Couper, D, Coviello, AD, D'Adamo, P, De Faire, U, De Geus, EJC, Deloukas, P, Döring, A, Smith, GD, Easton, DF, Eiriksdottir, G, Emilsson, V, Eriksson, J, Ferrucci, L, Folsom, AR, Foroud, T, Garcia, M, Gasparini, P, Geller, F, Gieger, C, Gudnason, V, Hall, P, Hankinson, SE, Ferreli, L, Heath, AC, Hernandez, DG, Hofman, A, Hu, FB, Illig, T, Järvelin, MR, Johnson, AD, Karasik, D, Khaw, KT, Kiel, DP, Kilpelänen, TO, Kolcic, I, Kraft, P, Launer, LJ, Laven, JSE, Li, S, Liu, J, Levy, D, Martin, NG, McArdle, WL, Melbye, M, Mooser, V, Murray, JC, Murray, SS, Nalls, MA, Navarro, P, Nelis, M, Ness, AR, and Northstone, K. "Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies." Nature Genetics 42, no. 12 (December 1, 2010): 1077-1085.  Full Text
    • Basaria, S, Coviello, AD, Travison, TG, Storer, TW, Farwell, WR, Jette, AM, Eder, R, Tennstedt, S, Ulloor, J, Zhang, A, Choong, K, Lakshman, KM, Mazer, NA, Miciek, R, Krasnoff, J, Elmi, A, Knapp, PE, Brooks, B, Appleman, E, Aggarwal, S, Bhasin, G, Hede-Brierley, L, Bhatia, A, Collins, L, LeBrasseur, N, Fiore, LD, and Bhasin, S. "Adverse events associated with testosterone administration." New England Journal of Medicine 363, no. 2 (July 8, 2010): 109-122.  Full Text
    • Krasnoff, JB, Basaria, S, Pencina, MJ, Jasuja, GK, Vasan, RS, Ulloor, J, Zhang, A, Coviello, A, Kelly-Hayes, M, D'Agostino, RB, Wolf, PA, Bhasin, S, and Murabito, JM. "Free testosterone levels are associated with mobility limitation and physical performance in community-dwelling men: the Framingham Offspring Study." The Journal of Clinical Endocrinology and Metabolism 95, no. 6 (June 2010): 2790-2799.  Full Text
    • Coviello, AD, Sam, S, Legro, RS, and Dunaif, A. "High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity." The Journal of Clinical Endocrinology and Metabolism 94, no. 11 (November 2009): 4361-4366.  Full Text
    • Herbst, KL, Coviello, AD, Chang, A, and Boyle, DL. "Lipomatosis-associated inflammation and excess collagen may contribute to lower relative resting energy expenditure in women with adiposis dolorosa." International Journal of Obesity (2005) 33, no. 9 (September 2009): 1031-1038.  Full Text
    • Coviello, AD. "Polycystic ovary syndrome: multiple pathways to a common phenotype?." Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 15, no. 4 (May 2009): 387-389.  Full Text
    • Bhasin, S, Zhang, A, Coviello, A, Jasuja, R, Ulloor, J, Singh, R, Vesper, H, and Vasan, RS. "The impact of assay quality and reference ranges on clinical decision making in the diagnosis of androgen disorders." Steroids 73, no. 13 (December 2008): 1311-1317.  Full Text
    • Sam, S, Coviello, AD, Sung, Y-A, Legro, RS, and Dunaif, A. "Metabolic phenotype in the brothers of women with polycystic ovary syndrome." Diabetes Care 31, no. 6 (June 2008): 1237-1241.  Full Text
    • Coviello, AD, Kaplan, B, Lakshman, KM, Chen, T, Singh, AB, and Bhasin, S. "Effects of graded doses of testosterone on erythropoiesis in healthy young and older men." The Journal of Clinical Endocrinology and Metabolism 93, no. 3 (March 2008): 914-919.  Full Text
    • Amory, JK, Coviello, AD, Page, ST, Anawalt, BD, Matsumoto, AM, and Bremner, WJ. "Serum 17-hydroxyprogesterone strongly correlates with intratesticular testosterone in gonadotropin-suppressed normal men receiving various dosages of human chorionic gonadotropin." Fertility and Sterility 89, no. 2 (February 2008): 380-386.  Full Text
    • Amory, JK, Page, ST, Anawalt, BD, Coviello, AD, Matsumoto, AM, and Bremner, WJ. "Elevated end-of-treatment serum INSL3 is associated with failure to completely suppress spermatogenesis in men receiving male hormonal contraception." Journal of Andrology 28, no. 4 (July 2007): 548-554.  Full Text
    • Bhasin, S, Enzlin, P, Coviello, A, and Basson, R. "Sexual dysfunction in men and women with endocrine disorders." Lancet (London, England) 369, no. 9561 (February 2007): 597-611. (Review)  Full Text
    • Coviello, AD, Lakshman, K, Mazer, NA, and Bhasin, S. "Differences in the apparent metabolic clearance rate of testosterone in young and older men with gonadotropin suppression receiving graded doses of testosterone." The Journal of Clinical Endocrinology and Metabolism 91, no. 11 (November 2006): 4669-4675.  Full Text
    • Coviello, AD, Legro, RS, and Dunaif, A. "Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance." The Journal of Clinical Endocrinology and Metabolism 91, no. 2 (February 2006): 492-497.  Full Text
    • Anawalt, BD, Amory, JK, Herbst, KL, Coviello, AD, Page, ST, Bremner, WJ, and Matsumoto, AM. "Intramuscular testosterone enanthate plus very low dosage oral levonorgestrel suppresses spermatogenesis without causing weight gain in normal young men: a randomized clinical trial." Journal of Andrology 26, no. 3 (May 2005): 405-413.  Full Text
    • Coviello, AD, Matsumoto, AM, Bremner, WJ, Herbst, KL, Amory, JK, Anawalt, BD, Sutton, PR, Wright, WW, Brown, TR, Yan, X, Zirkin, BR, and Jarow, JP. "Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression." The Journal of Clinical Endocrinology and Metabolism 90, no. 5 (May 2005): 2595-2602.  Full Text
    • Page, ST, Herbst, KL, Amory, JK, Coviello, AD, Anawalt, BD, Matsumoto, AM, and Bremner, WJ. "Testosterone administration suppresses adiponectin levels in men." Journal of Andrology 26, no. 1 (January 2005): 85-92.
    • Herbst, KL, Coviello, AD, Page, S, Amory, JK, Anawalt, BD, and Bremner, WJ. "A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in healthy young men." The Journal of Clinical Endocrinology and Metabolism 89, no. 12 (December 2004): 5959-5965.  Full Text
    • Coviello, AD, Bremner, WJ, Matsumoto, AM, Herbst, KL, Amory, JK, Anawalt, BD, Yan, X, Brown, TR, Wright, WW, Zirkin, BR, and Jarow, JP. "Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormonal contraceptive regimen." Journal of Andrology 25, no. 6 (November 2004): 931-938.  Full Text
    • Nusbaum, NJ. "Intensive insulin therapy in critically ill patients." The New England Journal of Medicine 346, no. 20 (May 2002): 1586-1588. (Letter)  Full Text
    • Feldman, HA, Longcope, C, Derby, CA, Johannes, CB, Araujo, AB, Coviello, AD, Bremner, WJ, and McKinlay, JB. "Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study." The Journal of Clinical Endocrinology and Metabolism 87, no. 2 (February 2002): 589-598.  Full Text
    • Goldstein, LB, and Coviello, A. "Post-lesion administration of the NMDA receptor antagonist MK-801 does not impair motor recovery after unilateral sensorimotor cortex injury in the rat." Brain Res 580, no. 1-2 (May 15, 1992): 129-136.  Link to Item
    • Goldstein, LB, Coviello, A, Miller, GD, and Davis, JN. "Norepinephrine depletion impairs motor recovery following sensorimotor cortex injury in the rat." Restor Neurol Neurosci 3, no. 1 (January 1, 1991): 41-47.  Full Text  Link to Item

  • Conference Papers

    • Ohlsson, C, Wallaschofski, H, Lunetta, KL, Stolk, L, Perry, JRB, Koster, A, Petersen, A-K, Eriksson, J, Lehtimäki, T, Huhtaniemi, IT, Hammond, GL, Maggio, M, Coviello, AD, EMAS Study Group, , Ferrucci, L, Heier, M, Hofman, A, Holliday, KL, Jansson, J-O, Kähönen, M, Karasik, D, Karlsson, MK, Kiel, DP, Liu, Y, Ljunggren, O, Lorentzon, M, Lyytikäinen, L-P, Meitinger, T, Mellström, D, Melzer, D, Miljkovic, I, Nauck, M, Nilsson, M, Penninx, B, Pye, SR, Vasan, RS, Reincke, M, Rivadeneira, F, Tajar, A, Teumer, A, Uitterlinden, AG, Ulloor, J, Viikari, J, Völker, U, Völzke, H, Wichmann, HE, Wu, T-S, Zhuang, WV, Ziv, E, Wu, FCW, Raitakari, O, Eriksson, A, Bidlingmaier, M, Harris, TB, Murray, A, de Jong, FH, Murabito, JM, Bhasin, S, Vandenput, L, and Haring, R. "Genetic determinants of serum testosterone concentrations in men." October 6, 2011.  Full Text
    • Zhai, G, Teumer, A, Stolk, L, Perry, JRB, Vandenput, L, Coviello, AD, Koster, A, Bell, JT, Bhasin, S, Eriksson, J, Eriksson, A, Ernst, F, Ferrucci, L, Frayling, TM, Glass, D, Grundberg, E, Haring, R, Hedman, AK, Hofman, A, Kiel, DP, Kroemer, HK, Liu, Y, Lunetta, KL, Maggio, M, Lorentzon, M, Mangino, M, Melzer, D, Miljkovic, I, MuTHER Consortium, , Nica, A, Penninx, BWJH, Vasan, RS, Rivadeneira, F, Small, KS, Soranzo, N, Uitterlinden, AG, Völzke, H, Wilson, SG, Xi, L, Zhuang, WV, Harris, TB, Murabito, JM, Ohlsson, C, Murray, A, de Jong, FH, Spector, TD, and Wallaschofski, H. "Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms." April 14, 2011.  Full Text
    • Coviello, AD, Zhuang, WV, Lunetta, KL, Ulloor, J, Zhang, A, Karasik, D, Kiel, DP, Bhasin, S, Vasan, RS, and Murabito, JM. "Heritability of Circulating Testosterone and SHBG in Adult Women from the Framingham Heart Study." June 2010.  Link to Item

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