Journal articleJournal of clinical and experimental neuropsychology · April 2026
IntroductionMeasurement bias - systematic errors that lead to inaccuracies in assessing latent constructs - threatens to invalidate analysis and interpretation of ourcome scores collected in the context of clinical trials, longtiudinal research, a ...
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Journal articleInternational journal for equity in health · October 2025
BackgroundDepression significantly impacts health systems worldwide, particularly in Latin America, where cultural stigmatization and misconceptions about mental health deter individuals from seeking help. Healthcare professionals' attitudes towar ...
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Journal articleAssessment · September 2025
The NIMH Research Domain Criteria (RDoC) initiative seeks to utilize multidimensional patterns of socio-cognitive behavior to improve understanding of mental illness. We aimed to evaluate the psychometric properties of a subset of RDoC tasks. Specifically, ...
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Journal articleNeurobiology of aging · September 2024
IntroductionThe "structural disconnection" hypothesis of cognitive aging suggests that deterioration of white matter (WM), especially myelin, results in cognitive decline, yet in vivo evidence is inconclusive.MethodsWe examined age differ ...
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Journal articleCerebral circulation - cognition and behavior · January 2024
As the emerging treatments that target grey matter pathology in Alzheimer's Disease have limited effectiveness, there is a critical need to identify new neural targets for treatments. White matter's (WM) metabolic vulnerability makes it a promising candida ...
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Journal articleCerebral circulation - cognition and behavior · January 2023
Metabolic syndrome (MetS) is a cluster of conditions that affects ∼25% of the global population, including excess adiposity, hyperglycemia, dyslipidemia, and elevated blood pressure. MetS is one of major risk factors not only for chronic diseases, but also ...
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Journal articleImaging neuroscience (Cambridge, Mass.) · January 2023
This meta-analysis and systematic review synthesized data from 30 longitudinal diffusion tensor imaging (DTI) studies on the magnitude, direction, spatial patterns, and modifiers of naturally occurring within-person changes in healthy adult white matter (W ...
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Journal articleFrontiers in neurology · January 2023
In the past 20 years, white matter (WM) microstructure has been studied predominantly using diffusion tensor imaging (DTI). Decreases in fractional anisotropy (FA) and increases in mean (MD) and radial diffusivity (RD) have been consistently reported in he ...
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Journal articleInternational journal of environmental research and public health · March 2022
Certain exposures related to agricultural work have been associated with neurological disorders. To date, few studies have included brain health measurements to link specific risk factors with possible neural mechanisms. Moreover, a synthesis of agricultur ...
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Journal articleNeuroImage · October 2021
White matter deterioration is associated with cognitive impairment in healthy aging and Alzheimer's disease. It is critical to identify interventions that can slow down white matter deterioration. So far, clinical trials have failed to demonstrate the bene ...
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Journal articleGaceta Medica De Caracas · January 1, 2021
Objectives: To determine the prevalence and severity of depression, anxiety, and stress in medical residents from the University Hospital of Maracaibo, Venezuela. Materials and methods: We conducted an observational, descriptive, and cross-sectional study ...
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Journal articleAmerican journal of hypertension · June 2018
BackgroundOrthostatic hypotension (OH) occurs when mechanisms regulating blood pressure (BP) levels after standing-up are altered. It is unclear how prevalence and risk factors for OH are different between sexes. We aimed to investigate sex differ ...
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