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Andrea Mendez Colmenares

House Staff
Medicine

Scholarly Works


Measurement bias for age, sex, and years of education in selected RDoC tasks.

Journal article Journal of clinical and experimental neuropsychology · April 2026 IntroductionMeasurement bias - systematic errors that lead to inaccuracies in assessing latent constructs - threatens to invalidate analysis and interpretation of ourcome scores collected in the context of clinical trials, longtiudinal research, a ... Full text Cite

Healthcare attitudes toward depression in Latin America: a latent class analysis from Argentina, Chile, Ecuador, Peru, and Venezuela using the Spanish-validated revised depression attitude questionnaire (SR-DAQ).

Journal article International journal for equity in health · October 2025 BackgroundDepression significantly impacts health systems worldwide, particularly in Latin America, where cultural stigmatization and misconceptions about mental health deter individuals from seeking help. Healthcare professionals' attitudes towar ... Full text Cite

Psychometric Evaluation of Cognitive and Positive Valence Tasks Chosen for the NIMH Research Domain Criteria Project.

Journal article Assessment · September 2025 The NIMH Research Domain Criteria (RDoC) initiative seeks to utilize multidimensional patterns of socio-cognitive behavior to improve understanding of mental illness. We aimed to evaluate the psychometric properties of a subset of RDoC tasks. Specifically, ... Full text Cite

Testing the structural disconnection hypothesis: Myelin content correlates with memory in healthy aging.

Journal article Neurobiology of aging · September 2024 IntroductionThe "structural disconnection" hypothesis of cognitive aging suggests that deterioration of white matter (WM), especially myelin, results in cognitive decline, yet in vivo evidence is inconclusive.MethodsWe examined age differ ... Full text Cite

Correlates of axonal content in healthy adult span: Age, sex, myelin, and metabolic health.

Journal article Cerebral circulation - cognition and behavior · January 2024 As the emerging treatments that target grey matter pathology in Alzheimer's Disease have limited effectiveness, there is a critical need to identify new neural targets for treatments. White matter's (WM) metabolic vulnerability makes it a promising candida ... Full text Cite

Metabolic syndrome and adiposity: Risk factors for decreased myelin in cognitively healthy adults.

Journal article Cerebral circulation - cognition and behavior · January 2023 Metabolic syndrome (MetS) is a cluster of conditions that affects ∼25% of the global population, including excess adiposity, hyperglycemia, dyslipidemia, and elevated blood pressure. MetS is one of major risk factors not only for chronic diseases, but also ... Full text Cite

Within-person changes in the aging white matter microstructure and their modifiers: A meta-analysis and systematic review of longitudinal diffusion tensor imaging studies.

Journal article Imaging neuroscience (Cambridge, Mass.) · January 2023 This meta-analysis and systematic review synthesized data from 30 longitudinal diffusion tensor imaging (DTI) studies on the magnitude, direction, spatial patterns, and modifiers of naturally occurring within-person changes in healthy adult white matter (W ... Full text Cite

Symmetric data-driven fusion of diffusion tensor MRI: Age differences in white matter.

Journal article Frontiers in neurology · January 2023 In the past 20 years, white matter (WM) microstructure has been studied predominantly using diffusion tensor imaging (DTI). Decreases in fractional anisotropy (FA) and increases in mean (MD) and radial diffusivity (RD) have been consistently reported in he ... Full text Cite

Risk Factors for Brain Health in Agricultural Work: A Systematic Review.

Journal article International journal of environmental research and public health · March 2022 Certain exposures related to agricultural work have been associated with neurological disorders. To date, few studies have included brain health measurements to link specific risk factors with possible neural mechanisms. Moreover, a synthesis of agricultur ... Full text Cite

White matter plasticity in healthy older adults: The effects of aerobic exercise.

Journal article NeuroImage · October 2021 White matter deterioration is associated with cognitive impairment in healthy aging and Alzheimer's disease. It is critical to identify interventions that can slow down white matter deterioration. So far, clinical trials have failed to demonstrate the bene ... Full text Cite

Prevalence of depression, anxiety and stress in medical residents from a Venezuelan hospital

Journal article Gaceta Medica De Caracas · January 1, 2021 Objectives: To determine the prevalence and severity of depression, anxiety, and stress in medical residents from the University Hospital of Maracaibo, Venezuela. Materials and methods: We conducted an observational, descriptive, and cross-sectional study ... Full text Cite

Risk Factors for Orthostatic Hypotension: Differences Between Elderly Men and Women.

Journal article American journal of hypertension · June 2018 BackgroundOrthostatic hypotension (OH) occurs when mechanisms regulating blood pressure (BP) levels after standing-up are altered. It is unclear how prevalence and risk factors for OH are different between sexes. We aimed to investigate sex differ ... Full text Cite