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James Andrew Alspaugh II

James B. Duke Distinguished Professor of Medicine
Medicine, Infectious Diseases
Duke Box 102359, Durham, NC 27710
DUMC Box 102359, 163 Hanes House, Trent Drive, Durham, NC 27710

Scholarly Works - Preprints


A cysteine-rich domain of the Cuf1 transcription factor is required for high copper stress sensing and fungal virulence.

Preprint · December 13, 2024 UNLABELLED: The ability to sense, import but also detoxify copper (Cu) has been shown to be crucial for microbial pathogens to survive within the host. Previous studies conducted with the opportunistic human fungal pathogen Cryptococcus neoformans ( Cn ) h ... Full text Link to item Cite