Scholars@Duke
Andrew John Armstrong

Andrew John Armstrong

George Barth Geller Distinguished Professor for Research in Cancer
Medicine, Medical Oncology
andrew.armstrong@duke.edu
Duke Box 103861, Durham, NC 27710
GSRB1 Room 3006, 905 La Salle St, Durham, NC 27710
Office hours

Scholarly Works - Preprints

Development of a STEAP1-Targeted Prostate Cancer Specific Antibody Drug Conjugate Platform with Immunostimulatory Properties.

Preprint · April 24, 2026 BACKGROUND: Patients with prostate cancer who develop androgen pathway modulation resistant (APMR) disease face lethal outcomes despite advances in androgen receptor-pathway inhibitors, chemotherapy, and PSMA-directed radioligands. Antibody-drug conjugates ... Full text Link to item Cite

NUAK2 is a therapeutically tractable regulator of RNA splicing and tumor progression in neuroendocrine prostate cancer.

Preprint · November 13, 2025 Prostate cancer (PC) remains the second leading cause of cancer-related mortality in men. The emergence of treatment-emergent neuroendocrine prostate cancer (NEPC) arising from androgen receptor (AR) pathway inhibition poses a significant clinical challeng ... Full text Open Access Link to item Cite