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Andrew Joseph Muir

Professor of Medicine
Medicine, Gastroenterology
Duke Box 3913, Durham, NC 27710
03137B Hosp South, Durham, NC 27710

Overview


  • Hepatitis CĀ 
  • Primary sclerosing cholangitis
  • Cirrhosis
  • Liver Transplantation
  • Clinical Trials
  • Healthcare disparities in liver diseaseĀ 
  • Outcomes Research

Current Appointments & Affiliations


Professor of Medicine · 2016 - Present Medicine, Gastroenterology, Medicine
Chief, Division of Gastroenterology in the Department of Medicine · 2014 - Present Medicine, Gastroenterology, Medicine
Member in the Duke Clinical Research Institute · 1993 - Present Duke Clinical Research Institute, Institutes and Centers
Core Faculty in Innovation & Entrepreneurship · 2021 - Present Duke Innovation & Entrepreneurship, University Initiatives & Academic Support Units

In the News


Published August 21, 2019
Hungry for Innovation: How a MEDx Dinner Led to a Newly Patented Medical Tool
Published June 17, 2015
Pill-form Hepatitis C treatment giving patients hope
Published May 11, 2015
Interferon-Free Therapy Clears Hepatitis C in 93 Percent of Patients in Trial

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Recent Publications


Short-chain per- and polyfluoroalkyl substances associate with elevated alanine aminotransferase: Cross-sectional analysis results from the STRIVE cohort.

Journal Article Environ Res · June 11, 2025 BACKGROUND: The impact of short-chain, low molecular weight polyfluoroalkyl substances (PFAS) and long-chain, high molecular weight PFAS on elevated alanine aminotransferase (ALT) remains unclear. Additionally, demographic and behavioral factors influencin ... Full text Link to item Cite

HBV-specific T-cell function is nonenhanced by tenofovir-induced decline in HBV viremia or HBsAg titer in chronic hepatitis B

Journal Article Hepatology Communications · May 16, 2025 Background: Chronic hepatitis B is associated with virus-specific and global T-cell dysfunction. We hypothesized that therapeutic reduction in serum HBV DNA, ALT, and HBsAg would restore HBV-specific T-cell function and modify T-cell regulatory phenotype, ... Full text Cite

Predictors of hepatocellular carcinoma in LR-M category lesions, a multi-institutional analysis.

Journal Article Abdom Radiol (NY) · April 28, 2025 PURPOSE: The Liver Imaging Reporting and Data System (LI-RADS, LR) provides a framework for diagnosing hepatocellular carcinoma (HCC, LR-5). However, not all HCCs meet LR-5 criteria and are instead categorized as LR-M, probably or definitely malignant but ... Full text Link to item Cite
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Recent Grants


Endocrinology and Metabolism Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029

The Southeastern Liver Health Cohort Study

ResearchCo Investigator · Awarded by North Carolina State University · 2023 - 2027

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Education, Training & Certifications


Duke University · 2001 M.H.S.
Duke University · 1993 M.D.