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Andrew Bradley West

Professor of Pharmacology and Cancer Biology
Pharmacology & Cancer Biology
MSRB III 5124, DUMC 103853, Durham, NC 27710
3 Genome Court, MSRB III 5th FL, Durham, NC 27710

Scholarly Works - Preprints


Accumulation of LRRK2-associated phospho-Rab12 degenerative lysosomes in tauopathies.

Preprint · June 9, 2025 Parkinson's disease (PD) pathogenic mutations in leucine-rich repeat kinase 2 (LRRK2) are associated with endolysosomal dysfunction across cell types, and carriers of LRRK2 mutations variably present with phosphorylated tau and α-synuclein deposits in post ... Full text Link to item Cite